Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide

Circulation

Volumn 104, Issue 10, 2001, Pages 1171-1175

  Isobe, Hirotaka ^a   Okajima, Kenji ^a   Uchiba, Mitsuhiro ^a   Mizutani, Akio ^a   Harada, Naoaki ^a   Nagasaki, Akitoshi ^a   Okabe, Kazutoshi ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Anticoagulants; Infection; Nitric oxide; Shock

Indexed keywords

ACTIVATED PROTEIN C; AMINOGUANIDINE; ANTICOAGULANT AGENT; ENDOTOXIN; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; SERINE PROTEINASE; THROMBIN INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; ENZYME ACTIVITY; GENE EXPRESSION; HYPOTENSION; LEUKOPENIA; LUNG; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; TISSUE LEVEL;

EID: 0035806897     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc3501.093799     Document Type: Article

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