A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-β1 signaling cascade

Journal of Biological Chemistry

Volumn 278, Issue 10, 2003, Pages 7790-7799

  Kobayashi, Hiroshi ^a   Suzuki, Mika ^a   Tanaka, Yoshiko ^a   Kanayama, Naohiro ^a   Terao, Toshihiko ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIVES; CELL CULTURE; ENZYMES; TUMORS;

METASTASIS;

BIOCHEMISTRY;

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; CALCIUM; CALCIUM CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE; NIFEDIPINE; PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN TYROSINE KINASE; SERINE PROTEINASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1; ULINASTATIN; UROKINASE; VERAPAMIL; MEMBRANE PROTEIN; MESSENGER RNA; SOYBEAN TRYPSIN INHIBITOR; SPINT2 PROTEIN, HUMAN; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; AUTOCRINE EFFECT; CALCIUM CELL LEVEL; CANCER INVASION; CELL INVASION; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; METASTASIS; NORTHERN BLOTTING; OVARY CANCER; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENETICS; METABOLISM; OVARY TUMOR; PATHOLOGY;

CALCIUM; FEMALE; HUMANS; MEMBRANE GLYCOPROTEINS; NEOPLASM INVASIVENESS; OVARIAN NEOPLASMS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RNA, MESSENGER; SERINE PROTEINASE INHIBITORS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRYPSIN INHIBITOR, KUNITZ SOYBEAN; TUMOR CELLS, CULTURED; URINARY PLASMINOGEN ACTIVATOR;

EID: 0037424469     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210407200     Document Type: Article

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