Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor

Biochemical Journal

Volumn 338, Issue 2, 1999, Pages 281-287

  Jong, Miek C ^a   Willems Van Dijk, Ko ^b   Dahlmans, Vivian E H ^a   Van Der Boom, Hans ^a   Kobayashi, Kunisha ^c,d   Oka, Kazuhito ^c   Siest, Gerard ^e   Chan, Lawrence ^c   Hofker, Marten H ^b   Havekes, Louis M ^a,b  

^a TNO   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d CHILDREN S NUTRITION RESEARCH CENTER   (United States)

^e Centre de Medecine Preventive   (France)

Author keywords

Apolipoprotein C; Gene therapy; Lipoproteins; Receptors

Indexed keywords

APOLIPOPROTEIN C1; APOLIPOPROTEIN E; LIPID; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADENOVIRUS; ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE TARGETING; HAMSTER; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; REVERSAL REACTION; TRANSGENIC MOUSE;

EID: 0033104838     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3380281     Document Type: Article

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