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Volumn 6, Issue 1, 2005, Pages 11-19

Effects of concurrent therapy with policosanol and omega-3 fatty acids on lipid profile and platelet aggregation in rabbits

Author keywords

[No Author keywords available]

Indexed keywords

ALKANOL; ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; DOTRIACONTANOL; HEPTACOSANOL; HEXACOSANOL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ICOSAPENTAENOIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NONACOSANOL; OCATACOSANOL; OMEGA 3 FATTY ACID; POLICOSANOL; TETRACOSANOL; TETRAICONTANOL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 13844318280     PISSN: 11745886     EISSN: None     Source Type: Journal    
DOI: 10.2165/00126839-200506010-00002     Document Type: Article
Times cited : (14)

References (58)
  • 1
    • 0021350001 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trial results: I. Reduction in the incidence of coronary heart disease
    • The Lipid Research Clinics Coronary Primary Prevention Trial results: I. Reduction in the incidence of coronary heart disease. JAMA 1984; 251: 351-64
    • (1984) JAMA , vol.251 , pp. 351-364
  • 2
    • 0021349709 scopus 로고
    • The lipid research clinics coronary primary prevention trial results: II. The relationship of reduction in the incidence of coronary heart disease to cholesterol-lowering
    • Lipid Research Clinic Program
    • Lipid Research Clinic Program. The lipid research clinics coronary primary prevention trial results: II. The relationship of reduction in the incidence of coronary heart disease to cholesterol-lowering. JAMA 1984; 251: 365-74
    • (1984) JAMA , vol.251 , pp. 365-374
  • 3
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-prevention with gemfibrozil in middle-aged men with dyslipidemia
    • Frick MH, Elo O, Happa K. Helsinki Heart Study: primary-prevention with gemfibrozil in middle-aged men with dyslipidemia. N Engl J Med 1987; 317: 1237-45
    • (1987) N. Engl. J. Med. , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Happa, K.3
  • 4
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-9
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 5
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
    • for the Cholesterol and Recurrent Events Trial Investigators
    • Sacks FM, Pfeffer MA, Moyé LA, et al. for the Cholesterol and Recurrent Events Trial Investigators. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996; 335: 1001-9
    • (1996) N. Engl. J. Med. , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moyé, L.A.3
  • 6
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and deaths with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and deaths with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-57
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1349-1357
  • 7
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • for the West of Scotland Coronary Prevention
    • Shepherd J, Cobbe SM, Ford I, et al. for the West of Scotland Coronary Prevention. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995; 333: 1301-7
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 8
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS
    • for the AFCAPS/ TexCAPS Research Group
    • Downs JR, Clearfield M, Weiss S, et al. for the AFCAPS/ TexCAPS Research Group. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. JAMA 1998; 279: 1615-22
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weiss, S.3
  • 9
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomized placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomized placebo-controlled trial. Lancet 2002; 360: 7-22
    • (2002) Lancet , vol.360 , pp. 7-22
  • 10
    • 0037164314 scopus 로고    scopus 로고
    • Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomized controlled study
    • on behalf of the PROSPER Study Group
    • Shepherd J, Blauw GJ, Murphy MB, et al. on behalf of the PROSPER Study Group. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomized controlled study. Lancet 2002; 360: 1623-30
    • (2002) Lancet , vol.360 , pp. 1623-1630
    • Shepherd, J.1    Blauw, G.J.2    Murphy, M.B.3
  • 11
    • 0035897696 scopus 로고    scopus 로고
    • Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel of Detection, Evaluation and Treatment of High Blood Cholesterol in Adults
    • Expert Panel of Detection, Evaluation and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-97
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 13
    • 0343081551 scopus 로고    scopus 로고
    • Policosanol
    • Mas R. Policosanol. Drugs of the Future 2000; 25: 569-86
    • (2000) Drugs of the Future , vol.25 , pp. 569-586
    • Mas, R.1
  • 14
    • 0028577437 scopus 로고
    • Cholesterol-lowering effects of policosanol in rabbits
    • Arruzazabala ML, Carbajal D, Más R, et al. Cholesterol-lowering effects of policosanol in rabbits. Biol Res 1994; 27: 205-8
    • (1994) Biol. Res. , vol.27 , pp. 205-208
    • Arruzazabala, M.L.1    Carbajal, D.2    Más, R.3
  • 15
    • 0035057937 scopus 로고    scopus 로고
    • The effects of D-003 and policosanol on the lipid profile and endothelemia cells in normocholesterolemic rabbits: A head to head comparison
    • Mendoza S, Gámez R, Noa M, et al. The effects of D-003 and policosanol on the lipid profile and endothelemia cells in normocholesterolemic rabbits: a head to head comparison. Curr Ther Res 2001; 62: 209-20
    • (2001) Curr. Ther. Res. , vol.62 , pp. 209-220
    • Mendoza, S.1    Gámez, R.2    Noa, M.3
  • 16
    • 0030857721 scopus 로고    scopus 로고
    • A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia
    • Ortensi G, Gladstein H, Valli H, et al. A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia. Curr Ther Res 1997; 58: 390-401
    • (1997) Curr. Ther. Res. , vol.58 , pp. 390-401
    • Ortensi, G.1    Gladstein, H.2    Valli, H.3
  • 17
    • 0032970949 scopus 로고    scopus 로고
    • Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors
    • Mas R, Castaño G, Illnait J, et al. Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors. Clin Pharmacol Ther 1998; 65: 439-47
    • (1998) Clin. Pharmacol. Ther. , vol.65 , pp. 439-447
    • Mas, R.1    Castaño, G.2    Illnait, J.3
  • 18
    • 0343526455 scopus 로고    scopus 로고
    • Effects of policosanol, pravastatin on lipid profile, platelet aggregation, endothelemia in older hypercholesterolemic patients
    • Castaño G, Más R, Arruzazabala ML, et al. Effects of policosanol, pravastatin on lipid profile, platelet aggregation, endothelemia in older hypercholesterolemic patients. Int J Clin Pharm Res 1999; XIX: 105-16
    • (1999) Int. J. Clin. Pharm. Res. , vol.19 , pp. 105-116
    • Castaño, G.1    Más, R.2    Arruzazabala, M.L.3
  • 19
    • 0033936923 scopus 로고    scopus 로고
    • Effect of policosanol on postmenopausal women with type II hypercholesterolemia
    • Castaño G, Más R, Fernández L, et al. Effect of policosanol on postmenopausal women with type II hypercholesterolemia. Gynecol Endocrinol 2000; 13: 187-95
    • (2000) Gynecol. Endocrinol. , vol.13 , pp. 187-195
    • Castaño, G.1    Más, R.2    Fernández, L.3
  • 20
    • 0034913131 scopus 로고    scopus 로고
    • Effects of policosanol in older hypercholesterolemic patients with coronary disease
    • Mas R, Castaño G, Fernández L, et al. Effects of policosanol in older hypercholesterolemic patients with coronary disease. Clin Drug Invest 2001; 21: 485-97
    • (2001) Clin. Drug. Invest. , vol.21 , pp. 485-497
    • Mas, R.1    Castaño, G.2    Fernández, L.3
  • 21
    • 0345505338 scopus 로고    scopus 로고
    • Comparison of the efficacy, safety and tolerability of policosanol versus atorvastatin in elderly patients with type II hypercholesterolaemia
    • Castańo, G, Mas R, Fernández L, et al. Comparison of the efficacy, safety and tolerability of policosanol versus atorvastatin in elderly patients with type II hypercholesterolaemia. Drugs Aging 2003; 20: 153-63
    • (2003) Drugs Aging , vol.20 , pp. 153-163
    • Castańo, G.1    Mas, R.2    Fernández, L.3
  • 22
    • 0028897637 scopus 로고
    • Treatment of hypercholesterolemia in NIDDM with policosanol
    • Torres O, Agramonte AJ, Illnait J, et al. Treatment of hypercholesterolemia in NIDDM with policosanol. Diabetes Care 1995; 18: 393-7
    • (1995) Diabetes Care , vol.18 , pp. 393-397
    • Torres, O.1    Agramonte, A.J.2    Illnait, J.3
  • 23
    • 0033358535 scopus 로고    scopus 로고
    • Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and non insulin dependent diabetes mellitus
    • Crespo N, Illnait J, Mas R, et al. Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and non insulin dependent diabetes mellitus. Int J Clin Pharmacol Res 1999; XIX: 105-16
    • (1999) Int. J. Clin. Pharmacol. Res. , vol.19 , pp. 105-116
    • Crespo, N.1    Illnait, J.2    Mas, R.3
  • 24
    • 0142074299 scopus 로고    scopus 로고
    • Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation on patients with dyslipidaemia and type 2 diabetes mellitus
    • Castańo G, Fernández L, Mas R, et al. Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation on patients with dyslipidaemia and type 2 diabetes mellitus. Clin Drug Invest 2003; 23: 639-50
    • (2003) Clin. Drug Invest. , vol.23 , pp. 639-650
    • Castańo, G.1    Fernández, L.2    Mas, R.3
  • 25
    • 0028568193 scopus 로고
    • Policosanol inhibits cholesterol biosynthesis and enhances LDL processing in cultured human fibroblasts
    • Menéndez R, Fernández I, Del Río A, et al. Policosanol inhibits cholesterol biosynthesis and enhances LDL processing in cultured human fibroblasts. Biol Res 1994; 27: 199-203
    • (1994) Biol. Res. , vol.27 , pp. 199-203
    • Menéndez, R.1    Fernández, I.2    Del Río, A.3
  • 26
    • 0343052967 scopus 로고    scopus 로고
    • Cholesterol-lowering effect of policosanol on rabbits with hypercholesterolemia induced by a wheat starch-casein diet
    • Menéndez R, Arruzazabala ML, Más R, et al. Cholesterol-lowering effect of policosanol on rabbits with hypercholesterolemia induced by a wheat starch-casein diet. Br J Nutr 1996; 77: 923-32
    • (1996) Br. J. Nutr. , vol.77 , pp. 923-932
    • Menéndez, R.1    Arruzazabala, M.L.2    Más, R.3
  • 27
    • 0035098624 scopus 로고    scopus 로고
    • Policosanol modulates HMGCoA reductase activity in cultured fibroblasts
    • Menéndez R, Amor A, Rodeiro I, et al. Policosanol modulates HMGCoA reductase activity in cultured fibroblasts. Arch Med Res 2001; 32: 8-12
    • (2001) Arch. Med. Res. , vol.32 , pp. 8-12
    • Menéndez, R.1    Amor, A.2    Rodeiro, I.3
  • 28
    • 0030295032 scopus 로고    scopus 로고
    • Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers
    • Arruzazabala ML, Valdés S, Más R, et al. Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers. Pharmacol Res 1996; 34: 181-5
    • (1996) Pharmacol. Res. , vol.34 , pp. 181-185
    • Arruzazabala, M.L.1    Valdés, S.2    Más, R.3
  • 29
    • 0032467742 scopus 로고    scopus 로고
    • Effect of policosanol on platelet aggregation in type II hypercholesterolemic patients
    • Arruzazabala ML, Más R, Molina V, et al. Effect of policosanol on platelet aggregation in type II hypercholesterolemic patients. Int J Tissue React 1998; XX: 119-24
    • (1998) Int. J. Tissue React. , vol.20 , pp. 119-124
    • Arruzazabala, M.L.1    Más, R.2    Molina, V.3
  • 30
    • 0033813254 scopus 로고    scopus 로고
    • Effects of policosanol treatment on the susceptibility of low density lipoprotein (LDL) isolated from healthy volunteers to oxidative modification in vitro
    • Menéndez; R, Más R, Amor AM, et al. Effects of policosanol treatment on the susceptibility of low density lipoprotein (LDL) isolated from healthy volunteers to oxidative modification in vitro. Br J Clin Pharmacol 2000; 50: 255-62
    • (2000) Br. J. Clin. Pharmacol. , vol.50 , pp. 255-262
    • Menéndez, R.1    Más, R.2    Amor, A.M.3
  • 31
    • 0033823403 scopus 로고    scopus 로고
    • Effects of policosanol on the low density lipoprotein (LDL) isolated on hypercholesterolemic patients at high coronary risk to in vitro copper-mediated lipid peroxidation: A randomised, double-blinded pilot study
    • Menéndez R, Más R, Amor A, et al. Effects of policosanol on the low density lipoprotein (LDL) isolated on hypercholesterolemic patients at high coronary risk to in vitro copper-mediated lipid peroxidation: a randomised, double-blinded pilot study. Curr Ther Res 2000; 61: 609-20
    • (2000) Curr. Ther. Res. , vol.61 , pp. 609-620
    • Menéndez, R.1    Más, R.2    Amor, A.3
  • 32
    • 0027957267 scopus 로고
    • A 12-month study of policosanol oral toxicity in Sprague-Dawley rats
    • Alemán C, Más R, Hernández C, et al. A 12-month study of policosanol oral toxicity in Sprague-Dawley rats. Toxicol Lett 1994; 70: 77-87
    • (1994) Toxicol. Lett. , vol.70 , pp. 77-87
    • Alemán, C.1    Más, R.2    Hernández, C.3
  • 33
    • 0028122593 scopus 로고
    • Effect of policosanol chronically administered in male monkeys (Macaca arctoides)
    • Rodríguez C, Mesa R, Más R, et al. Effect of policosanol chronically administered in male monkeys (Macaca arctoides). Food Chem Toxicol 1994; 32: 565-75
    • (1994) Food Chem. Toxicol. , vol.32 , pp. 565-575
    • Rodríguez, C.1    Mesa, R.2    Más, R.3
  • 34
    • 0028174497 scopus 로고
    • Teratogenic and reproductive studies of policosanol in the rat and rabbit
    • Rodríguez MD, García H. Teratogenic and reproductive studies of policosanol in the rat and rabbit. Teratog Carcinog Mutagan 1994; 14: 107-13
    • (1994) Teratog. Carcinog. Mutagan , vol.14 , pp. 107-113
    • Rodríguez, M.D.1    García, H.2
  • 35
    • 0028144949 scopus 로고
    • Toxicity of policosanol in Beagle dogs: One year study
    • Mesa AR, Más R, Noa M, et al. Toxicity of policosanol in Beagle dogs: one year study. Toxicol Lett 1994; 73: 81-90
    • (1994) Toxicol. Lett. , vol.73 , pp. 81-90
    • Mesa, A.R.1    Más, R.2    Noa, M.3
  • 36
    • 0028033806 scopus 로고
    • Carcinogenicity of policosanol in Sprague Dawley rats: A 24-month study
    • Alemán CL, Más R, Noa M, et al. Carcinogenicity of policosanol in Sprague Dawley rats: a 24-month study. Teratog Carcinog Mutagan 1994; 14: 239-49
    • (1994) Teratog. Carcinog. Mutagan , vol.14 , pp. 239-249
    • Alemán, C.L.1    Más, R.2    Noa, M.3
  • 37
    • 0031557124 scopus 로고    scopus 로고
    • Multigeneration reproduction study of policosanol in rats
    • Rodríguez MD, Sánchez M, García H. Multigeneration reproduction study of policosanol in rats. Toxicol Lett 1997; 90: 97-106
    • (1997) Toxicol. Lett. , vol.90 , pp. 97-106
    • Rodríguez, M.D.1    Sánchez, M.2    García, H.3
  • 38
    • 0034906478 scopus 로고    scopus 로고
    • A 6-month study on the toxicity of high doses of policosanol orally administered to Sprague Dawley rats
    • Gámez R, Alemán CL, Mas R, et al. A 6-month study on the toxicity of high doses of policosanol orally administered to Sprague Dawley rats. J Med Food 2001; 4: 57-66
    • (2001) J. Med. Food , vol.4 , pp. 57-66
    • Gámez, R.1    Alemán, C.L.2    Mas, R.3
  • 39
    • 0037315079 scopus 로고    scopus 로고
    • Cardiovascular disease and long chain omega-3 fatty acids
    • Harris WS, Park Y, Isley WL. Cardiovascular disease and long chain omega-3 fatty acids. Curr Opin Lipidol 2003; 14: 9-14
    • (2003) Curr. Opin. Lipidol. , vol.14 , pp. 9-14
    • Harris, W.S.1    Park, Y.2    Isley, W.L.3
  • 40
    • 0038495550 scopus 로고    scopus 로고
    • The role of omega-3 fatty acids in the secondary prevention of cardiovascular disease
    • Lee KW, Lip GV. The role of omega-3 fatty acids in the secondary prevention of cardiovascular disease. QJM 2003; 96: 465-80
    • (2003) QJM , vol.96 , pp. 465-480
    • Lee, K.W.1    Lip, G.V.2
  • 41
    • 1542541539 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease
    • Richtner WO. Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease. Eur J Med Res 2003; 8: 332-6
    • (2003) Eur. J. Med. Res. , vol.8 , pp. 332-336
    • Richtner, W.O.1
  • 42
    • 0037307256 scopus 로고    scopus 로고
    • n-3 polyunsaturated fatty acids, fatal ischemic heart disease and non fatal myocardial infarction in older adults: The Cardiovascular Health Study
    • Lemaitre RN, King IB, Mozaffarian D, et al. n-3 polyunsaturated fatty acids, fatal ischemic heart disease and non fatal myocardial infarction in older adults: the Cardiovascular Health Study. Am J Clin Nutr 2003; 77: 319-25
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 319-325
    • Lemaitre, R.N.1    King, I.B.2    Mozaffarian, D.3
  • 43
    • 0037051975 scopus 로고    scopus 로고
    • Fish and omega-3 fatty acid intake and risk of coronary heart disease in women
    • Hu FB, Bronner L, Willett WC, et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA 2002; 287: 1815-21
    • (2002) JAMA , vol.287 , pp. 1815-1821
    • Hu, F.B.1    Bronner, L.2    Willett, W.C.3
  • 44
    • 0043197396 scopus 로고    scopus 로고
    • Antiarrhythmic effects of omega-3 fatty acids: From epidemiology to bedside
    • De Caterina R, Madonna R, Zucchi R, et al. Antiarrhythmic effects of omega-3 fatty acids: from epidemiology to bedside. Am Heart J 2003; 146: 420-30
    • (2003) Am. Heart J. , vol.146 , pp. 420-430
    • De Caterina, R.1    Madonna, R.2    Zucchi, R.3
  • 45
    • 0035144938 scopus 로고    scopus 로고
    • Long-chain omega 3 fatty acids, blood lipids and cardiovascular reduction
    • Mori TA, Beilin LJ. Long-chain omega 3 fatty acids, blood lipids and cardiovascular reduction. Curr Opin Lipidol 2001; 12: 11-7
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 11-17
    • Mori, T.A.1    Beilin, L.J.2
  • 46
    • 0024320531 scopus 로고
    • Effect of dietary omega-3-fatty acid on serum lipids, platelet function, and atherosclerosis in Watanabe heritable hyperlipidemic rabbits
    • Clubb FJ, Schmitz JM, Butler JM, et al. Effect of dietary omega-3-fatty acid on serum lipids, platelet function, and atherosclerosis in Watanabe heritable hyperlipidemic rabbits. Arteriosclerosis 1989; 9: 529-37
    • (1989) Arteriosclerosis , vol.9 , pp. 529-537
    • Clubb, F.J.1    Schmitz, J.M.2    Butler, J.M.3
  • 47
    • 0019488877 scopus 로고
    • Separation of serum high-density lipoprotein for cholesterol determination: Ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride
    • Seigler L, Wu WT. Separation of serum high-density lipoprotein for cholesterol determination: ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride. Clin Chem 1981; 27: 838-41
    • (1981) Clin. Chem. , vol.27 , pp. 838-841
    • Seigler, L.1    Wu, W.T.2
  • 48
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy IR, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Clin Chem 1972; 18: 499-502
    • (1972) Clin. Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, I.R.2    Fredrickson, D.S.3
  • 49
    • 0346367328 scopus 로고
    • Aggregation of blood platelets by adenosine diphosphate and its reversal
    • Born G. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature (L) 1962; 194: 927-30
    • (1962) Nature (L) , vol.194 , pp. 927-930
    • Born, G.1
  • 50
    • 0031034530 scopus 로고    scopus 로고
    • Interactions between dietary fat, fish and fish oils and their effects on platelet function in men at risk of cardiovascular disease
    • Mori TA, Beilin LJ, Burke V, et al. Interactions between dietary fat, fish and fish oils and their effects on platelet function in men at risk of cardiovascular disease. Arterioscler Thromb Vasc Biol 1997; 17: S79-82
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17
    • Mori, T.A.1    Beilin, L.J.2    Burke, V.3
  • 51
    • 0035700623 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids and coronary thrombosis
    • Kristensen SD, Iversen AM, Schmidt EB. N-3 polyunsaturated fatty acids and coronary thrombosis. Lipids 2001; 36 Suppl.: S79-82
    • (2001) Lipids , vol.36 , Issue.SUPPL.
    • Kristensen, S.D.1    Iversen, A.M.2    Schmidt, E.B.3
  • 52
    • 0347319081 scopus 로고    scopus 로고
    • Omega 3 fatty acids and cardiovascular disease: Fishing for a natural treatment
    • Din JN, Newby DE, Flapan AD. Omega 3 fatty acids and cardiovascular disease: fishing for a natural treatment. BMJ 2004; 32B: 30-5
    • (2004) BMJ , vol.32 B , pp. 30-35
    • Din, J.N.1    Newby, D.E.2    Flapan, A.D.3
  • 53
    • 0002223528 scopus 로고
    • Estudio farmacológico de la interacción entre el policosanol y la aspirina en animales de experimentación
    • Arruzazabala ML, Carbajal D, Molina V, et al. Estudio farmacológico de la interacción entre el policosanol y la aspirina en animales de experimentación. Rev Iberoam Tromb Hemost 1992; 5: 17-20
    • (1992) Rev. Iberoam. Tromb. Hemost. , vol.5 , pp. 17-20
    • Arruzazabala, M.L.1    Carbajal, D.2    Molina, V.3
  • 54
    • 0027183580 scopus 로고
    • Effect of policosanol on cerebral ischemia in mongolian gerbils: Role of prostacyclin and thromboxane A2
    • Arruzazabala ML, Carbajal D, Molina V, et al. Effect of policosanol on cerebral ischemia in mongolian gerbils: role of prostacyclin and thromboxane A2. Prostagl Leukotr Essent Fatty Acids 1993; 49: 695-7
    • (1993) Prostagl. Leukotr. Essent. Fatty Acids , vol.49 , pp. 695-697
    • Arruzazabala, M.L.1    Carbajal, D.2    Molina, V.3
  • 55
    • 0031962129 scopus 로고    scopus 로고
    • Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers
    • Carbajal D, Arruzazabala ML, Valdés S, et al. Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers. Prostagl Leukotr Essent Fatty Acids 1998; 58: 61-4
    • (1998) Prostagl. Leukotr. Essent. Fatty Acids , vol.58 , pp. 61-64
    • Carbajal, D.1    Arruzazabala, M.L.2    Valdés, S.3
  • 56
    • 0029838529 scopus 로고    scopus 로고
    • Antiplatelet therapy
    • Schafer A. Antiplatelet therapy. Am J Med 1996; 101: 199-209
    • (1996) Am. J. Med. , vol.101 , pp. 199-209
    • Schafer, A.1
  • 57
    • 0031257654 scopus 로고    scopus 로고
    • Comparative study of policosanol, aspirin and the combination of policosanol-aspirin on platelet aggregation in healthy volunteers
    • Arruzazabala ML, Valdés S, Más R, et al. Comparative study of policosanol, aspirin and the combination of policosanol-aspirin on platelet aggregation in healthy volunteers. Pharmacol Res 1998; 36: 293-7
    • (1998) Pharmacol. Res. , vol.36 , pp. 293-297
    • Arruzazabala, M.L.1    Valdés, S.2    Más, R.3
  • 58
    • 0028948513 scopus 로고
    • Inhibition of thromboxane biosynthesis and platelet function by simvastatin in type IIa hypercholesterolemia
    • Notarbartolo A, Davi G, Averna M, et al. Inhibition of thromboxane biosynthesis and platelet function by simvastatin in type IIa hypercholesterolemia. Arterioscler Thromb Vasc Biol 1995; 15: 247-51
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 247-251
    • Notarbartolo, A.1    Davi, G.2    Averna, M.3


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