메뉴 건너뛰기




Volumn 58, Issue 6, 1997, Pages 390-401

A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia

Author keywords

Elderly; Hypercholesterolemia; Policosanol; Simvastatin

Indexed keywords

ANTILIPEMIC AGENT; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NATURAL PRODUCT; POLICOSANOL; SIMVASTATIN; TRIACYLGLYCEROL;

EID: 0030857721     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(97)80099-9     Document Type: Article
Times cited : (68)

References (63)
  • 1
    • 0023025526 scopus 로고
    • Is the relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356 222 primary screenings of the Multiple Risk Factor Intervention Trial
    • Stamler J, Wentworth D, Neaton JD, for the MRFIT Research Group. Is the relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356 222 primary screenings of the Multiple Risk Factor Intervention Trial. JAMA. 1986;256:2823-2827.
    • (1986) JAMA , vol.256 , pp. 2823-2827
    • Stamler, J.1    Wentworth, D.2    Neaton, J.D.3
  • 2
    • 0021350001 scopus 로고
    • The lipid research clinics coronary primary prevention trial results. I. Reduction in the incidence of coronary heart disease
    • Lipid Research Clinics Program. The lipid research clinics coronary primary prevention trial results. I. Reduction in the incidence of coronary heart disease. JAMA. 1984;251: 351-364.
    • (1984) JAMA , vol.251 , pp. 351-364
  • 3
    • 0021349709 scopus 로고
    • The lipid research clinics coronary primary prevention trial results. II. The relationship of reduction in the incidence of coronary heart disease to cholesterol lowering
    • Lipid Research Clinics Program. The lipid research clinics coronary primary prevention trial results. II. The relationship of reduction in the incidence of coronary heart disease to cholesterol lowering. JAMA. 1984;251:365-374.
    • (1984) JAMA , vol.251 , pp. 365-374
  • 4
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-intervention trial with gemfibrozil in middle-aged men with dislipidemia
    • Frick MH, Elo D, Haapa K, et al. Helsinki Heart Study: Primary-intervention trial with gemfibrozil in middle-aged men with dislipidemia. NEJM. 1987;317:1237-1245.
    • (1987) NEJM , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, D.2    Haapa, K.3
  • 6
    • 0023893277 scopus 로고
    • Prevention of cardiovascular disease among elderly
    • Karvonen MJ. Prevention of cardiovascular disease among elderly. Bull WHO. 1988;66: 7-14.
    • (1988) Bull WHO , vol.66 , pp. 7-14
    • Karvonen, M.J.1
  • 7
    • 0025019678 scopus 로고
    • Is elevated serum cholesterol level a risk factor for coronary heart disease in the elderly?
    • Benfante R, Reed D. Is elevated serum cholesterol level a risk factor for coronary heart disease in the elderly? JAMA. 1990;263:393-396.
    • (1990) JAMA , vol.263 , pp. 393-396
    • Benfante, R.1    Reed, D.2
  • 8
    • 0026342525 scopus 로고
    • Clinical consideration regarding treatment of hypercholesterolemia in the elderly
    • Bilheimer DW. Clinical consideration regarding treatment of hypercholesterolemia in the elderly. Atherosclerosis. 1991;91(Suppl):S35-S57.
    • (1991) Atherosclerosis , vol.91 , Issue.SUPPL.
    • Bilheimer, D.W.1
  • 9
    • 0025316371 scopus 로고
    • Hypercholesterolemia in elderly persons: Resolving the treatment dilemma
    • Denke MA, Grundy SM. Hypercholesterolemia in elderly persons: Resolving the treatment dilemma. Ann Intern Med. 1990;112:780-792.
    • (1990) Ann Intern Med , vol.112 , pp. 780-792
    • Denke, M.A.1    Grundy, S.M.2
  • 10
    • 0024447750 scopus 로고
    • Clinical pharmacokinetic considerations in the elderly. An update
    • Dawling S, Crome P. Clinical pharmacokinetic considerations in the elderly. An update. Clin Pharmacokinet. 1989;17:236-241.
    • (1989) Clin Pharmacokinet , vol.17 , pp. 236-241
    • Dawling, S.1    Crome, P.2
  • 11
    • 0020621944 scopus 로고
    • Pharmacological basis for developing rational drug regimens for elderly patients
    • Goldberg PB, Roberts J. Pharmacological basis for developing rational drug regimens for elderly patients. Med Clin North Am. 1983;67:315-331.
    • (1983) Med Clin North Am , vol.67 , pp. 315-331
    • Goldberg, P.B.1    Roberts, J.2
  • 12
    • 0025909542 scopus 로고
    • The ambiguous relation between aging and adverse drug reactions
    • Gurwitz JH, Avorn J. The ambiguous relation between aging and adverse drug reactions. Ann Intern Med. 1991;114:956-958.
    • (1991) Ann Intern Med , vol.114 , pp. 956-958
    • Gurwitz, J.H.1    Avorn, J.2
  • 13
    • 0011325925 scopus 로고
    • Efecto del policosanol sobre el perfil lipídico de conejos normocolesterolémicos
    • Arruzazabala ML, Carbajal D, Más R, et al. Efecto del policosanol sobre el perfil lipídico de conejos normocolesterolémicos. Arch Ven Farmacol Ter. 1992;11:80-86.
    • (1992) Arch Ven Farmacol Ter , vol.11 , pp. 80-86
    • Arruzazabala, M.L.1    Carbajal, D.2    Más, R.3
  • 14
    • 0001853063 scopus 로고
    • Estudio del efecto sobre lipidos y lipoproteínas séricos y de la tolerancia al tratamiento oral con dosis crecientes de policosanol en monos (Macaca arctoides)
    • Rodríguez C, Mesa R, Más R, et al. Estudio del efecto sobre lipidos y lipoproteínas séricos y de la tolerancia al tratamiento oral con dosis crecientes de policosanol en monos (Macaca arctoides). Arch Ven Farmacol Ter. 1992;11:74-79.
    • (1992) Arch Ven Farmacol Ter , vol.11 , pp. 74-79
    • Rodríguez, C.1    Mesa, R.2    Más, R.3
  • 15
    • 0002237390 scopus 로고
    • Efecto de la administración oral del policosanol sobre el metabolismo lipídico de ratas normocolesterolémicas
    • Menéndez R, Fraga V, Sotolongo V, et al. Efecto de la administración oral del policosanol sobre el metabolismo lipídico de ratas normocolesterolémicas. Rev Mex Cien Farm. 1993; 24:16-18.
    • (1993) Rev Mex Cien Farm , vol.24 , pp. 16-18
    • Menéndez, R.1    Fraga, V.2    Sotolongo, V.3
  • 16
    • 0028568193 scopus 로고
    • Policosanol inhibits cholesterol biosynthesis and enhances LDL processing in cultured human fibroblasts
    • Menéndez R, Fernández I, Del Río A, et al. Policosanol inhibits cholesterol biosynthesis and enhances LDL processing in cultured human fibroblasts. Biol Res. 1994;27:199-203.
    • (1994) Biol Res , vol.27 , pp. 199-203
    • Menéndez, R.1    Fernández, I.2    Del Río, A.3
  • 17
    • 0344175903 scopus 로고
    • Effect of ateromixol (policosanol) on serum lipids and lipoproteins in healthy volunteers
    • Hernández F, Illnait J, Más R, et al. Effect of ateromixol (policosanol) on serum lipids and lipoproteins in healthy volunteers. Curr Ther Res. 1992;51:1-8.
    • (1992) Curr Ther Res , vol.51 , pp. 1-8
    • Hernández, F.1    Illnait, J.2    Más, R.3
  • 18
    • 0001801534 scopus 로고
    • Efectos del tratamiento con ateromixol (PPG) (5 mg) en pacientes con hiperlipoproteinemia tipo II
    • Castaño G, Zardoya R, Illnait J, et al. Efectos del tratamiento con ateromixol (PPG) (5 mg) en pacientes con hiperlipoproteinemia tipo II. Prog Cien Méd. 1991;5:21-28.
    • (1991) Prog Cien Méd , vol.5 , pp. 21-28
    • Castaño, G.1    Zardoya, R.2    Illnait, J.3
  • 19
    • 0026670821 scopus 로고
    • Efficacy and safety of policosanol in patients with primary hypercholesterolemia
    • Pons P, Más R, Illnait J, et al. Efficacy and safety of policosanol in patients with primary hypercholesterolemia. Curr Ther Res. 1992;52:507-513.
    • (1992) Curr Ther Res , vol.52 , pp. 507-513
    • Pons, P.1    Más, R.2    Illnait, J.3
  • 20
    • 0002384735 scopus 로고
    • Estudio comparativo doble ciego de la eficacia y tolerancia del policosanol vs bezafibrato en pacientes con hiperlipidemias tipo II
    • Soltero I, Fuenmayor I, Colmenares J. Estudio comparativo doble ciego de la eficacia y tolerancia del policosanol vs bezafibrato en pacientes con hiperlipidemias tipo II. Arch Ven Farmacol Ter. 1993;12:71-76.
    • (1993) Arch Ven Farmacol Ter , vol.12 , pp. 71-76
    • Soltero, I.1    Fuenmayor, I.2    Colmenares, J.3
  • 21
    • 0027439338 scopus 로고
    • Effects of successive dose increases of policosanol on the lipid profile and tolerability of treatment
    • Aneiros E, Calderón B, Más R, et al. Effects of successive dose increases of policosanol on the lipid profile and tolerability of treatment. Curr Ther Res. 1993;54:304-312.
    • (1993) Curr Ther Res , vol.54 , pp. 304-312
    • Aneiros, E.1    Calderón, B.2    Más, R.3
  • 22
    • 0028897637 scopus 로고
    • Treatment of hypercholesterolemia in NIDDM with policosanol
    • Torres O, Agramonte AJ, Illnait J, et al. Treatment of hypercholesterolemia in NIDDM with policosanol. Diabetes Care. 1995;18:393-397.
    • (1995) Diabetes Care , vol.18 , pp. 393-397
    • Torres, O.1    Agramonte, A.J.2    Illnait, J.3
  • 23
    • 0028227198 scopus 로고
    • Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolemia and tolerability to treatment
    • Pons P, Rodríguez M, Robaina C, et al. Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolemia and tolerability to treatment. J Clin Pharmacol Res. 1994;14:27-33.
    • (1994) J Clin Pharmacol Res , vol.14 , pp. 27-33
    • Pons, P.1    Rodríguez, M.2    Robaina, C.3
  • 24
    • 0027978416 scopus 로고
    • One year efficacy and safety of policosanol in patients with type II hypercholesterolemia
    • Pons P, Rodríguez M, Más R, et al. One year efficacy and safety of policosanol in patients with type II hypercholesterolemia. Curr Ther Res. 1994;55:1084-1092.
    • (1994) Curr Ther Res , vol.55 , pp. 1084-1092
    • Pons, P.1    Rodríguez, M.2    Más, R.3
  • 25
    • 0028963194 scopus 로고
    • Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia
    • Aneiros E, Más R, Calderón B, et al. Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia. Curr Ther Res. 1995;56:176-182.
    • (1995) Curr Ther Res , vol.56 , pp. 176-182
    • Aneiros, E.1    Más, R.2    Calderón, B.3
  • 26
    • 0028931289 scopus 로고
    • One-year study of the efficacy and safety of policosanol (5 mg twice daily) in the treatment of type II hypercholesterolemia
    • Castaño G, Más R, Nodarse M, et al. One-year study of the efficacy and safety of policosanol (5 mg twice daily) in the treatment of type II hypercholesterolemia. Curr Ther Res. 1995;56:296-304.
    • (1995) Curr Ther Res , vol.56 , pp. 296-304
    • Castaño, G.1    Más, R.2    Nodarse, M.3
  • 27
    • 0029083862 scopus 로고
    • One year study on the effect of policosanol (5 mg-twice-a-day) on lipid profile in patients with type II hypercholesterolemia
    • Canetti M, Moreira M, Illnait J, et al. One year study on the effect of policosanol (5 mg-twice-a-day) on lipid profile in patients with type II hypercholesterolemia. Adv Ther. 1995;12:245-254.
    • (1995) Adv Ther , vol.12 , pp. 245-254
    • Canetti, M.1    Moreira, M.2    Illnait, J.3
  • 28
    • 0029589212 scopus 로고    scopus 로고
    • A two year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinemia
    • Canetti M, Moreira M, Más R, et al. A two year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinemia. Int J Clin Pharmacol Res. 1997;15:159-165.
    • (1997) Int J Clin Pharmacol Res , vol.15 , pp. 159-165
    • Canetti, M.1    Moreira, M.2    Más, R.3
  • 30
    • 0002891838 scopus 로고
    • Estudio genotoxico del ateromixol (PPG), un nuevo medicamento hipolipemiante
    • Ferná;ndez SI, Rendón A, de las Cajigas A, et al. Estudio genotoxico del ateromixol (PPG), un nuevo medicamento hipolipemiante. Rev Cienc Biol. 1991;22:98-101.
    • (1991) Rev Cienc Biol , vol.22 , pp. 98-101
    • Ferná1    ndez, S.I.2    Rendón, A.3    De Las Cajigas, A.4
  • 31
    • 0028174497 scopus 로고
    • Teratogenic and reproductive studies of policosanol in the rat and rabbit
    • Rodríguez MD, García H. Teratogenic and reproductive studies of policosanol in the rat and rabbit. Teratog Carcinog Mutag. 1994;14:107-113.
    • (1994) Teratog Carcinog Mutag , vol.14 , pp. 107-113
    • Rodríguez, M.D.1    García, H.2
  • 32
    • 0027957267 scopus 로고
    • A 12 month study of policosanol oral toxicity in Sprague-Dawley rats
    • Alemán CL, Más R, Hernández C, et al. A 12 month study of policosanol oral toxicity in Sprague-Dawley rats. Toxicol Lett. 1994;70:77-87.
    • (1994) Toxicol Lett , vol.70 , pp. 77-87
    • Alemán, C.L.1    Más, R.2    Hernández, C.3
  • 33
    • 0028144949 scopus 로고
    • Toxicity of policosanol in beagle dogs: One year study
    • Mesa AR, Más R, Noa M, et al. Toxicity of policosanol in beagle dogs: One year study. Toxicol Lett. 1994;73:81-90.
    • (1994) Toxicol Lett , vol.73 , pp. 81-90
    • Mesa, A.R.1    Más, R.2    Noa, M.3
  • 34
    • 0028122593 scopus 로고
    • Effect of policosanol chronically administered in male monkeys (Macaca arctoides)
    • Rodrígues C, Mesa R, Más R, et al. Effect of policosanol chronically administered in male monkeys (Macaca arctoides). Food Chem Toxicol. 1994;32:565-575.
    • (1994) Food Chem Toxicol , vol.32 , pp. 565-575
    • Rodrígues, C.1    Mesa, R.2    Más, R.3
  • 35
    • 0028033806 scopus 로고
    • Carcinogenicity of policosanol in Sprague Dawley rats: A 24 month study
    • Alemán CL, Más R, Noa M, et al. Carcinogenicity of policosanol in Sprague Dawley rats: A 24 month study. Teratog Carcinog Mutag. 1994;14:239-249.
    • (1994) Teratog Carcinog Mutag , vol.14 , pp. 239-249
    • Alemán, C.L.1    Más, R.2    Noa, M.3
  • 36
    • 0029164702 scopus 로고
    • Carcinogenicity of policosanol in mice: An 18 month study
    • Alemán C, Noa M, Cerejido E, et al. Carcinogenicity of policosanol in mice: An 18 month study. Food Chem Toxicol. 1995;33:573-578.
    • (1995) Food Chem Toxicol , vol.33 , pp. 573-578
    • Alemán, C.1    Noa, M.2    Cerejido, E.3
  • 37
    • 0027513940 scopus 로고
    • Effects of policosanol in elderly hypercholesterolemic patients
    • Pons P, Jiménez A, Rodríguez M, et al. Effects of policosanol in elderly hypercholesterolemic patients. Curr Ther Res. 1993;53:265-269.
    • (1993) Curr Ther Res , vol.53 , pp. 265-269
    • Pons, P.1    Jiménez, A.2    Rodríguez, M.3
  • 38
    • 0029155739 scopus 로고
    • Efficacy and tolerability of policosanol in elderly patients with type II hyperlipoproteinemia: A 12-month study
    • Castaño G, Canetti M, Moreira M, et al. Efficacy and tolerability of policosanol in elderly patients with type II hyperlipoproteinemia: A 12-month study. Curr Ther Res. 1995;56: 819-828.
    • (1995) Curr Ther Res , vol.56 , pp. 819-828
    • Castaño, G.1    Canetti, M.2    Moreira, M.3
  • 39
    • 0018939225 scopus 로고
    • Mevinolin, a highly potent competitive inhibitor of hydroxymethyl glutaryl-coenzyme A reductase and a cholesterol lowering agent
    • Alberts AW, Chen J, Kuron G, et al. Mevinolin, a highly potent competitive inhibitor of hydroxymethyl glutaryl-coenzyme A reductase and a cholesterol lowering agent. Proc Natl Acad Sci USA. 1980;77:3957-3961.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 3957-3961
    • Alberts, A.W.1    Chen, J.2    Kuron, G.3
  • 40
    • 0028364181 scopus 로고
    • Therapeutic use of lovastatin in the treatment of hypercholesterolemia
    • Illingworth DR. Therapeutic use of lovastatin in the treatment of hypercholesterolemia. Clin Ther. 1994;16:2-26.
    • (1994) Clin Ther , vol.16 , pp. 2-26
    • Illingworth, D.R.1
  • 41
    • 0023185909 scopus 로고
    • Current pharmacologic treatment of elevated serum cholesterol
    • Matti J, Tikkanen MD, Eski A, et al. Current pharmacologic treatment of elevated serum cholesterol. Circulation. 1987;76:529-533.
    • (1987) Circulation , vol.76 , pp. 529-533
    • Matti, J.1    Tikkanen, M.D.2    Eski, A.3
  • 42
    • 0002573175 scopus 로고
    • The long-term tolerability profile of lovastatin and simvastatin
    • Mitchel YB. The long-term tolerability profile of lovastatin and simvastatin. Atherosclerosis. 1992;97(Suppl):S33-S39.
    • (1992) Atherosclerosis , vol.97 , Issue.SUPPL.
    • Mitchel, Y.B.1
  • 43
    • 0024972456 scopus 로고
    • Simvastatin: The clinical profile
    • Walker JF. Simvastatin: The clinical profile. Am J Med. 1989;87(Suppl 4A):44S-48S.
    • (1989) Am J Med , vol.87 , Issue.SUPPL. 4A
    • Walker, J.F.1
  • 44
    • 8544238663 scopus 로고
    • Comparison of simvastatin and ciprofibrate in the treatment of primary hypercholesterolaemia - A French multicentre study
    • Farnier M, and the French Study Group. Comparison of simvastatin and ciprofibrate in the treatment of primary hypercholesterolaemia - a French multicentre study. Atherosclerosis. 1992;97(Suppl):S59-S66.
    • (1992) Atherosclerosis , vol.97 , Issue.SUPPL.
    • Farnier, M.1
  • 45
    • 0024544020 scopus 로고
    • Effects of simvastatin and probucol in hypercholesterolemia
    • Pietro DA, Alexander S, Mantell G, et al. (Simvastatin Multicenter Study Group II). Effects of simvastatin and probucol in hypercholesterolemia. Am J Cardiol. 1989;63:682-686.
    • (1989) Am J Cardiol , vol.63 , pp. 682-686
    • Pietro, D.A.1    Alexander, S.2    Mantell, G.3
  • 46
    • 0024972418 scopus 로고
    • Comparison of low doses of simvastatin and gemfibrozil in the treatment of elevated plasma cholesterol: A multicenter study
    • Tikkanen MJ, Bocanegra TS, Walker JF, et al. Comparison of low doses of simvastatin and gemfibrozil in the treatment of elevated plasma cholesterol: A multicenter study. Am J Med. 1989;87(Suppl 4A):47S-49S.
    • (1989) Am J Med , vol.87 , Issue.SUPPL. 4A
    • Tikkanen, M.J.1    Bocanegra, T.S.2    Walker, J.F.3
  • 47
    • 0023847607 scopus 로고
    • Comparison between simvastatin and bezafibrate in effect on plasma lipoproteins and apolipoproteins in primary hypercholesterolemia
    • Schulzack P, Bojanovski M, Jochim A, et al. Comparison between simvastatin and bezafibrate in effect on plasma lipoproteins and apolipoproteins in primary hypercholesterolemia. Lancet. 1988;1:611-613.
    • (1988) Lancet , vol.1 , pp. 611-613
    • Schulzack, P.1    Bojanovski, M.2    Jochim, A.3
  • 48
    • 8544238663 scopus 로고
    • Comparison of simvastatin and ciprofibrate in the treatment of hypercholesterolemia
    • Farnier M, and the French Study Group. Comparison of simvastatin and ciprofibrate in the treatment of hypercholesterolemia. Atherosclerosis. 1992;97:59-66.
    • (1992) Atherosclerosis , vol.97 , pp. 59-66
    • Farnier, M.1
  • 49
    • 0025688791 scopus 로고
    • Safety, tolerability and efficacy of simvastatin and fenofibrate - A multicenter study
    • Ziegler O, Drouin P. Safety, tolerability and efficacy of simvastatin and fenofibrate - a multicenter study. Cardiology. 1990;77:50-57.
    • (1990) Cardiology , vol.77 , pp. 50-57
    • Ziegler, O.1    Drouin, P.2
  • 50
    • 0028273352 scopus 로고
    • Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia
    • Farnier M, Bonnefous F, Debbas N, et al. Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia. Arch Intern Med. 1994;154:441-449.
    • (1994) Arch Intern Med , vol.154 , pp. 441-449
    • Farnier, M.1    Bonnefous, F.2    Debbas, N.3
  • 51
    • 0024396392 scopus 로고
    • Dose-dependent lipid-lowering effects of simvastatin (MK-733) in the elderly
    • Kuhn P, Darioli R, Bovet P, et al. Dose-dependent lipid-lowering effects of simvastatin (MK-733) in the elderly. Curr Ther Res. 1989;46:381-389.
    • (1989) Curr Ther Res , vol.46 , pp. 381-389
    • Kuhn, P.1    Darioli, R.2    Bovet, P.3
  • 53
    • 8044251981 scopus 로고
    • A comparative study of simvastatin versus pravastatin in patients with primary hypercholesterolemia
    • Malini PL, de Divitiis O, di Somma S, et al. A comparative study of simvastatin versus pravastatin in patients with primary hypercholesterolemia. Atherosclerosis. 1992; 97(Suppl):S41-S47.
    • (1992) Atherosclerosis , vol.97 , Issue.SUPPL.
    • Malini, P.L.1    De Divitiis, O.2    Di Somma, S.3
  • 54
    • 0026341760 scopus 로고
    • Long-term efficacy and safety of simvastatin alone and in combination therapy in treatment of hypercholesterolemia
    • Mölgaard J, Lundh BJ, Von Schenck H, et al. Long-term efficacy and safety of simvastatin alone and in combination therapy in treatment of hypercholesterolemia. Atherosclerosis. 1991;91(Suppl):S21-S28.
    • (1991) Atherosclerosis , vol.91 , Issue.SUPPL.
    • Mölgaard, J.1    Lundh, B.J.2    Von Schenck, H.3
  • 55
    • 8544262352 scopus 로고
    • Efficacy and safety of simvastatin and pravastatin in patients with primary hypercholesterolemia (a comparative study in different countries)
    • The European Study Group. Efficacy and safety of simvastatin and pravastatin in patients with primary hypercholesterolemia (a comparative study in different countries). Am J Cardiol. 1992;70:1-7.
    • (1992) Am J Cardiol , vol.70 , pp. 1-7
  • 56
    • 0019488877 scopus 로고
    • Separation of serum high-density lipoprotein for cholesterol determination: Ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride
    • Seigler L, Wu WT. Separation of serum high-density lipoprotein for cholesterol determination: Ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride. Clin Chem. 1981;27:838-841.
    • (1981) Clin Chem , vol.27 , pp. 838-841
    • Seigler, L.1    Wu, W.T.2
  • 57
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density-lipoprotein cholesterol in plasma without preparative ultracentrifugue
    • Friedewald WT, Levy RI, Friederickson SD. Estimation of the concentration of low-density-lipoprotein cholesterol in plasma without preparative ultracentrifugue. Clin Chem. 1972;18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Friederickson, S.D.3
  • 58
    • 0024150417 scopus 로고
    • An overview of lipid lowering drugs
    • Illingworth DR. An overview of lipid lowering drugs. Drugs. 1988;36(Suppl 3):63-71.
    • (1988) Drugs , vol.36 , Issue.3 SUPPL. , pp. 63-71
    • Illingworth, D.R.1
  • 59
    • 0024972417 scopus 로고
    • Efficacy and tolerability of simvastatin (MK-733)
    • Stalenhoff ARH, Marc JTM, Stuyt PMJ. Efficacy and tolerability of simvastatin (MK-733). Am J Med. 1989;87(Suppl 4A):4A-395-4A-435.
    • (1989) Am J Med , vol.87 , Issue.SUPPL. 4A
    • Stalenhoff, A.R.H.1    Marc, J.T.M.2    Stuyt, P.M.J.3
  • 61
    • 0026608091 scopus 로고
    • The efficacy and safety of pravastatin and simvastatin in patients with primary hypercholesterolemia
    • Volpe R, Area M, Ginnetti MG, et al. The efficacy and safety of pravastatin and simvastatin in patients with primary hypercholesterolemia. Curr Ther Res. 1992;51:422-430.
    • (1992) Curr Ther Res , vol.51 , pp. 422-430
    • Volpe, R.1    Area, M.2    Ginnetti, M.G.3
  • 62
    • 8544271818 scopus 로고
    • Efficacy and safety of simvastatin in long-term treatment of severe primary hypercholesterolemia
    • Halpem MJ, ed. John Libbey and Company Ltd.
    • Volpe R, Area M, Ginnetti MG, et al. Efficacy and safety of simvastatin in long-term treatment of severe primary hypercholesterolemia. In: Halpem MJ, ed. Molecular Biology of Atherosclerosis. John Libbey and Company Ltd.; 1992:619-621.
    • (1992) Molecular Biology of Atherosclerosis , pp. 619-621
    • Volpe, R.1    Area, M.2    Ginnetti, M.G.3
  • 63
    • 0025612463 scopus 로고
    • Effects of simvastatin, bezafibrate and gemfibrozil on the quantity and composition of plasma lipoproteins
    • Nakandakare E, Garcia RC, Rocha JC, et al. Effects of simvastatin, bezafibrate and gemfibrozil on the quantity and composition of plasma lipoproteins. Atherosclerosis. 1990;85:211-217.
    • (1990) Atherosclerosis , vol.85 , pp. 211-217
    • Nakandakare, E.1    Garcia, R.C.2    Rocha, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.