Investigation into 64Cu-labeled Bis(selenosemicarbazone) and Bis(thiosemicarbazone) complexes as hypoxia imaging agents

Nuclear Medicine and Biology

Volumn 32, Issue 2, 2005, Pages 147-156

  McQuade, Paul ^a   Martin, Katherine E ^b   Castle, Thomas C ^b   Went, Michael J ^b   Blower, Philip J ^b   Welch, Michael J ^a,c   Lewis, Jason S ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENT   (United Kingdom)

^c USA   (United States)

Author keywords

Bis(thiosemicarbazones); Cu radionuclides; Hypoxia; MicroPET

Indexed keywords

DIACETYL BIS(N 4 ETHYLTHIOSEMICARBAZONE) CU 64; DIACETYL BIS(N 4 METHYLTHIOSEMICARBAZONE) CU 64; DIACETYL BIS(SELENOSEMICARBAZONE) CU 64; RADIOLIGAND; UNCLASSIFIED DRUG; COPPER; DIAGNOSTIC AGENT; OXYGEN; RADIOPHARMACEUTICAL AGENT; SEMICARBAZONE DERIVATIVE;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CANCER TRANSPLANTATION; CARCINOMA CELL; COMPARATIVE STUDY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; OXYGEN CONCENTRATION; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; ANIMAL; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; CELL HYPOXIA; EXPERIMENTAL NEOPLASM; FEMALE; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; SCINTISCANNING; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; COPPER RADIOISOTOPES; FEMALE; ISOTOPE LABELING; MAMMARY NEOPLASMS, ANIMAL; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED BALB C; ORGAN SPECIFICITY; OXYGEN; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SEMICARBAZONES; TISSUE DISTRIBUTION;

EID: 13844305880     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2004.10.004     Document Type: Article

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