-
2
-
-
0033599057
-
Disorders of iron metabolism
-
Andrews NC. Disorders of iron metabolism. N Engl J Med 1999; 341: 1986-95.
-
(1999)
N Engl J Med
, vol.341
, pp. 1986-1995
-
-
Andrews, N.C.1
-
3
-
-
0033861745
-
A navel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A, et al. A navel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 2000; 5: 299-309.
-
(2000)
Mol Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
-
4
-
-
0034733635
-
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
-
Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 2000; 275: 19906-12.
-
(2000)
J Biol Chem
, vol.275
, pp. 19906-19912
-
-
Abboud, S.1
Haile, D.J.2
-
5
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, et al. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 2000; 403: 776-81.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
-
6
-
-
0035793856
-
An iron-regulated ferric reductase associated with the absorption of dietary iron
-
McKie AT, Barrow D, Latunde-Dada GO, et al. An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 2001; 291: 1755-9.
-
(2001)
Science
, vol.291
, pp. 1755-1759
-
-
McKie, A.T.1
Barrow, D.2
Latunde-Dada, G.O.3
-
7
-
-
0346461664
-
Ferroportin/IREG-1/MTP-1/ SLC40A1 modulates the uptake of iron at the apical membrane of enterocytes
-
Thomas C, Oates PS. Ferroportin/IREG-1/MTP-1/ SLC40A1 modulates the uptake of iron at the apical membrane of enterocytes. Gut 2004; 53: 44-9.
-
(2004)
Gut
, vol.53
, pp. 44-49
-
-
Thomas, C.1
Oates, P.S.2
-
8
-
-
0032909207
-
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
-
Vulpe CD, Kuo YM, Murphy TL, et al. Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat Genet 1999; 21: 195-9.
-
(1999)
Nat Genet
, vol.21
, pp. 195-199
-
-
Vulpe, C.D.1
Kuo, Y.M.2
Murphy, T.L.3
-
9
-
-
1642451921
-
Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse
-
Kuo YM, Su T, Chen H, et al. Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse. Gut 2004; 53: 201-6.
-
(2004)
Gut
, vol.53
, pp. 201-206
-
-
Kuo, Y.M.1
Su, T.2
Chen, H.3
-
10
-
-
2942588454
-
Role of copper in the proteosome-mediated degradation of the multicopper oxidase hephaestin
-
Nittis T, Gitlin JD. Role of copper in the proteosome-mediated degradation of the multicopper oxidase hephaestin. J Biol Chem 2004; 279: 25696-702.
-
(2004)
J Biol Chem
, vol.279
, pp. 25696-25702
-
-
Nittis, T.1
Gitlin, J.D.2
-
11
-
-
1842504248
-
Aceruloplasminemia: An inherited neurodegenerative disease with impairment of iron homeostasis
-
Xu X, Pin S, Gathinji M, Fuchs R, Harris ZL. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Ann N Y Acad Sci 2004; 1012: 299-305.
-
(2004)
Ann N Y Acad Sci
, vol.1012
, pp. 299-305
-
-
Xu, X.1
Pin, S.2
Gathinji, M.3
Fuchs, R.4
Harris, Z.L.5
-
12
-
-
0029921680
-
A permease-oxidase complex involved in high-affinity iron uptake in yeast
-
Stearman R, Yuan DS, Yamaguchi-Iwai Y, Klausner RD, Dancis A. A permease-oxidase complex involved in high-affinity iron uptake in yeast. Science 1996; 271: 1552-7.
-
(1996)
Science
, vol.271
, pp. 1552-1557
-
-
Stearman, R.1
Yuan, D.S.2
Yamaguchi-Iwai, Y.3
Klausner, R.D.4
Dancis, A.5
-
13
-
-
0026673757
-
Coordination of cellular iron metabolism by post-transcriptional gene regulation
-
Kuhn LC, Hentze MW. Coordination of cellular iron metabolism by post-transcriptional gene regulation. J Inorg Biochem 1992; 47: 183-95.
-
(1992)
J Inorg Biochem
, vol.47
, pp. 183-195
-
-
Kuhn, L.C.1
Hentze, M.W.2
-
14
-
-
0344974223
-
Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation
-
Liu XB, Hill P, Haile DJ. Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation. Blood Cells Mol Dis 2002; 29: 315-26.
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 315-326
-
-
Liu, X.B.1
Hill, P.2
Haile, D.J.3
-
15
-
-
0242521527
-
The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression
-
Lymboussaki A, Pignotti E, Montosi G, Garuti C, Haile DJ, Pietrangelo A. The role of the iron responsive element in the control of ferroportin1/IREG1/ MTP1 gene expression. J Hepatol 2003; 39: 710-5.
-
(2003)
J Hepatol
, vol.39
, pp. 710-715
-
-
Lymboussaki, A.1
Pignotti, E.2
Montosi, G.3
Garuti, C.4
Haile, D.J.5
Pietrangelo, A.6
-
16
-
-
0345688910
-
Iron loading and erythrophagocytosis increase ferroportin1 (FPN1) expression in J774 macrophages
-
Knutson MD, Vofo MR, Haile DJ, Wessling-Resnick M. Iron loading and erythrophagocytosis increase ferroportin1 (FPN1) expression in J774 macrophages. Blood 2003; 102: 4191-7.
-
(2003)
Blood
, vol.102
, pp. 4191-4197
-
-
Knutson, M.D.1
Vofo, M.R.2
Haile, D.J.3
Wessling-Resnick, M.4
-
17
-
-
1542357700
-
Copper-induced ferroportin1 expression in J774 macrophages is associated with increased iron efflux
-
Chung J, Haile DJ, Wessling-Resnick M. Copper-induced ferroportin1 expression in J774 macrophages is associated with increased iron efflux. Proc Natl Acad Sci USA 2004; 101: 2700-5.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2700-2705
-
-
Chung, J.1
Haile, D.J.2
Wessling-Resnick, M.3
-
18
-
-
10844258104
-
Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization
-
e-pub ahead of print
-
Nemath E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Gantz T, Kaplan J. Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization. Science 2004; 28: [e-pub ahead of print].
-
(2004)
Science
, vol.28
-
-
Nemath, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
Gantz, T.7
Kaplan, J.8
-
19
-
-
0037259376
-
L'Hepcidine, un régulateur majeur du métabolisme du fer
-
Beaumont C, Nicolas G, Vaulont S. L'Hepcidine, un régulateur majeur du métabolisme du fer. Hématologie 2003; 9: 27-36.
-
(2003)
Hématologie
, vol.9
, pp. 27-36
-
-
Beaumont, C.1
Nicolas, G.2
Vaulont, S.3
-
20
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Caurselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001; 276: 7811-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Caurselaud, B.3
-
21
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I, et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001; 98: 8780-5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
22
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas G, Bennoun M, Parteu A, et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci USA 2002; 99: 4596-601.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Parteu, A.3
-
23
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 2003; 33: 21-2.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
-
24
-
-
0037847496
-
Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis
-
Nicolas G, Viatte L, Lau DQ, et al. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nat Genet 2003; 34: 97-101.
-
(2003)
Nat Genet
, vol.34
, pp. 97-101
-
-
Nicolas, G.1
Viatte, L.2
Lau, D.Q.3
-
25
-
-
1642464613
-
Diversity of folds in animal toxins acting on ion channels
-
Mouhat S, Jouirou B, Mosbah A, De Waard M, Sabatier JM. Diversity of folds in animal toxins acting on ion channels. Biochem J 2004; 378: 717-26.
-
(2004)
Biochem J
, vol.378
, pp. 717-726
-
-
Mouhat, S.1
Jouirou, B.2
Mosbah, A.3
De Waard, M.4
Sabatier, J.M.5
-
26
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 2004; 113: 1271-6.
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
-
27
-
-
0037131264
-
Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation
-
Yang F, Liu XB, Quinones M, Melby PC, Ghio A, Haile DJ. Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation. J Biol Chem 2002; 277: 39786-91.
-
(2002)
J Biol Chem
, vol.277
, pp. 39786-39791
-
-
Yang, F.1
Liu, X.B.2
Quinones, M.3
Melby, P.C.4
Ghio, A.5
Haile, D.J.6
-
28
-
-
0036727925
-
Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats
-
Frazer DM, Wilkins SJ, Becker EM, et al. Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology 2002; 123: 835-44.
-
(2002)
Gastroenterology
, vol.123
, pp. 835-844
-
-
Frazer, D.M.1
Wilkins, S.J.2
Becker, E.M.3
-
29
-
-
4644320292
-
Inhibition of iron transport across human intestinal epithelial cells by hepcidin
-
Yamaji S, Sharp P, Ramesh B, Srai SK. Inhibition of iron transport across human intestinal epithelial cells by hepcidin. Blood 2004; 104: 2178-80.
-
(2004)
Blood
, vol.104
, pp. 2178-2180
-
-
Yamaji, S.1
Sharp, P.2
Ramesh, B.3
Srai, S.K.4
-
30
-
-
0037954281
-
HFE, the MHC and hemochromatosis: Paradigm for an extended function for MHC class I
-
Cardoso CS, De Sousa M. HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I. Tissue Antigens 2003; 61: 263-75.
-
(2003)
Tissue Antigens
, vol.61
, pp. 263-275
-
-
Cardoso, C.S.1
De Sousa, M.2
-
31
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 2004; 36: 77-82.
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
32
-
-
1442306702
-
Non-HFE hemochromatosis
-
Pietrangelo A. Non-HFE hemochromatosis. Hepatology 2004; 39: 21-9.
-
(2004)
Hepatology
, vol.39
, pp. 21-29
-
-
Pietrangelo, A.1
-
33
-
-
0033517341
-
Hereditary hemochromatosis in adults without pathogenic mutations in the hemochromatosis gene
-
Pietrangelo A, Montosi G, Totaro A, et al. Hereditary hemochromatosis in adults without pathogenic mutations in the hemochromatosis gene. N Engl J Med 1999; 341: 725-32.
-
(1999)
N Engl J Med
, vol.341
, pp. 725-732
-
-
Pietrangelo, A.1
Montosi, G.2
Totaro, A.3
-
34
-
-
17944380796
-
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
-
Montosi G, Donovan A, Totaro A, et al. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 2001; 108: 619-23.
-
(2001)
J Clin Invest
, vol.108
, pp. 619-623
-
-
Montosi, G.1
Donovan, A.2
Totaro, A.3
-
35
-
-
0242724167
-
Dominant hemochromatosis due to N144H mutation of SLC11A3: Clinical and biological characteristics
-
Njajou OT, De Jong G, Berghuis B, et al. Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics. Blood Cells Mol Dis 2002; 29: 439-43.
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 439-443
-
-
Njajou, O.T.1
De Jong, G.2
Berghuis, B.3
-
36
-
-
10744232713
-
Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroporrtn1) gene
-
Gordeuk VR, Caleffi A, Corradini E, et al. Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroporrtn1) gene. Blood Cells Mol Dis 2003; 31: 299-304.
-
(2003)
Blood Cells Mol Dis
, vol.31
, pp. 299-304
-
-
Gordeuk, V.R.1
Caleffi, A.2
Corradini, E.3
-
37
-
-
0242724153
-
Ferroportin1 (SCL40A1) variant associated with iron overload in African-Americans
-
Beutler E, Bartan JC, Felitti VJ, et al. Ferroportin1 (SCL40A1) variant associated with iron overload in African-Americans. Blood Cells Mol Dis 2003; 31: 305-9.
-
(2003)
Blood Cells Mol Dis
, vol.31
, pp. 305-309
-
-
Beutler, E.1
Bartan, J.C.2
Felitti, V.J.3
-
38
-
-
1642280929
-
Autosomal dominant iron overload due to a novel mutation of ferroportin1 associated with parenchymal iron loading and cirrhosis
-
Wallace DF, Clark RM, Harley HA, Subramaniam VN. Autosomal dominant iron overload due to a novel mutation of ferroportin1 associated with parenchymal iron loading and cirrhosis. J Hepatol 2004; 40: 710-3.
-
(2004)
J Hepatol
, vol.40
, pp. 710-713
-
-
Wallace, D.F.1
Clark, R.M.2
Harley, H.A.3
Subramaniam, V.N.4
-
39
-
-
0038536855
-
Autosomal dominant reticuloendothelial iron overload (HFE type 4) due to a new missense mutation in the ferroportin1 gene (SLC11A3) in a large French-Canadian family
-
Rivard SR, Lanzara C, Grimard D, et al. Autosomal dominant reticuloendothelial iron overload (HFE type 4) due to a new missense mutation in the ferroportin1 gene (SLC11A3) in a large French-Canadian family. Haematologica 2003; 88: 824-6.
-
(2003)
Haematologica
, vol.88
, pp. 824-826
-
-
Rivard, S.R.1
Lanzara, C.2
Grimard, D.3
-
40
-
-
0037100382
-
Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin1 gene (SLC11A3)
-
Devalia V, Carter K, Walker AP, et al. Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin1 gene (SLC11A3). Blood 2002; 100: 695-7.
-
(2002)
Blood
, vol.100
, pp. 695-697
-
-
Devalia, V.1
Carter, K.2
Walker, A.P.3
-
41
-
-
0037100517
-
Novel mutation in ferroportin1 is associated with autosomal dominant hemochromatosis
-
Wallace DF, Pedersen P, Dixon JL, et al. Novel mutation in ferroportin1 is associated with autosomal dominant hemochromatosis. Blood 2002; 100: 692-4.
-
(2002)
Blood
, vol.100
, pp. 692-694
-
-
Wallace, D.F.1
Pedersen, P.2
Dixon, J.L.3
-
42
-
-
0037100383
-
A valine deletion of ferroportin1: A common mutation in hemochromastosis type 4
-
Roetto A, Merryweather-Clarke AT, Daraio F, et al. A valine deletion of ferroportin1: a common mutation in hemochromastosis type 4. Blood 2002; 100: 733-4.
-
(2002)
Blood
, vol.100
, pp. 733-734
-
-
Roetto, A.1
Merryweather-Clarke, A.T.2
Daraio, F.3
-
43
-
-
18744400781
-
Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3)
-
Cazzola M, Cremonesi L, Papaioannou M, et al. Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3). Br J Haematol 2002; 119: 539-46.
-
(2002)
Br J Haematol
, vol.119
, pp. 539-546
-
-
Cazzola, M.1
Cremonesi, L.2
Papaioannou, M.3
-
44
-
-
0037622887
-
A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient
-
Arden KE, Wallace DF, Dixon JL, et al. A novel mutation in ferroportin1 is associated with haemochromatosis in a Solomon Islands patient. Gut 2003; 52: 1215-7.
-
(2003)
Gut
, vol.52
, pp. 1215-1217
-
-
Arden, K.E.1
Wallace, D.F.2
Dixon, J.L.3
-
45
-
-
0037860450
-
Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations
-
Hetet G, Devaux I, Soufir N, Grandchamp B, Beaumont C. Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations. Blood 2003; 102: 1904-10.
-
(2003)
Blood
, vol.102
, pp. 1904-1910
-
-
Hetet, G.1
Devaux, I.2
Soufir, N.3
Grandchamp, B.4
Beaumont, C.5
-
46
-
-
0011062558
-
Hereditary hyperferritinemia cataract syndrome
-
Templeton DM, ed . New York: Marcel Dekker
-
Beaumont C, Girelli D. Hereditary hyperferritinemia cataract syndrome. In: Templeton DM, ed. Molecular and cellular iron transport. New York: Marcel Dekker, 2002: 761-74.
-
(2002)
Molecular and Cellular Iron Transport
, pp. 761-774
-
-
Beaumont, C.1
Girelli, D.2
-
47
-
-
0742272103
-
The ferroportin disease
-
Pietrangelo A. The ferroportin disease. Blood Cells Mol Dis 2004; 32: 131-8.
-
(2004)
Blood Cells Mol Dis
, vol.32
, pp. 131-138
-
-
Pietrangelo, A.1
-
48
-
-
10744219904
-
Novel mutation in ferroportin1 gene is associated with autosomal dominant iron overload
-
Jouanolle AM, Douabin-Gicquel V, Halimi C, et al. Novel mutation in ferroportin1 gene is associated with autosomal dominant iron overload. J Hepatol 2003; 39: 286-9.
-
(2003)
J Hepatol
, vol.39
, pp. 286-289
-
-
Jouanolle, A.M.1
Douabin-Gicquel, V.2
Halimi, C.3
|