메뉴 건너뛰기




Volumn 49, Issue 3, 2000, Pages 411-417

The novel hypoglycemic agent YM440 normalizes hyperglycemia without changing body fat weight in diabetic db/db mice

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BIS[4 [(3,5 DIOXO 1,2,4 OXADIAZOLIDIN 2 YL)METHYL]PHENOXY]BUT 2 ENE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; FATTY ACID BINDING PROTEIN; GLUCOSE; MESSENGER RNA; ORAL ANTIDIABETIC AGENT; OXADIAZOLE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; TROGLITAZONE; UNCLASSIFIED DRUG; YM 440;

EID: 0034021443     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(00)90440-2     Document Type: Article
Times cited : (38)

References (35)
  • 1
    • 0031823401 scopus 로고    scopus 로고
    • Importance of glucose control
    • Edelman SV: Importance of glucose control. Med Clin North Am 82:665-687, 1998
    • (1998) Med Clin North Am , vol.82 , pp. 665-687
    • Edelman, S.V.1
  • 2
    • 0024160854 scopus 로고
    • Characterization of new oral antidiabetic agent CS-045
    • Fujiwara T, Yoshioka S, Yoshioka T, et al: Characterization of new oral antidiabetic agent CS-045. Diabetes 31:1549-1558, 1988
    • (1988) Diabetes , vol.31 , pp. 1549-1558
    • Fujiwara, T.1    Yoshioka, S.2    Yoshioka, T.3
  • 3
    • 0026517631 scopus 로고
    • Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects
    • Suter SL, Nolan JJ, Wallace P, et al: Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care 15:193-203, 1992
    • (1992) Diabetes Care , vol.15 , pp. 193-203
    • Suter, S.L.1    Nolan, J.J.2    Wallace, P.3
  • 4
    • 0032568310 scopus 로고    scopus 로고
    • Effect of troglitazone in insulin-treated patients with type II diabetes mellitus
    • Schwartz S, Raskin P, Fonseca V, et al: Effect of troglitazone in insulin-treated patients with type II diabetes mellitus. N Engl J Med 338:861-866, 1998
    • (1998) N Engl J Med , vol.338 , pp. 861-866
    • Schwartz, S.1    Raskin, P.2    Fonseca, V.3
  • 5
    • 0027303172 scopus 로고
    • In vivo metformin treatment ameliorates insulin resistance: Evidence for potentiation of insulin-induced translocation and increased functional activity of glucose transporters in obese (fa/fa) Zucker rat adipocytes
    • Matthaei S, Reibold JP, Hamann A, et al: In vivo metformin treatment ameliorates insulin resistance: Evidence for potentiation of insulin-induced translocation and increased functional activity of glucose transporters in obese (fa/fa) Zucker rat adipocytes. Endocrinology 133:304-311, 1993
    • (1993) Endocrinology , vol.133 , pp. 304-311
    • Matthaei, S.1    Reibold, J.P.2    Hamann, A.3
  • 6
    • 0029133235 scopus 로고
    • Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
    • Stumvoll M, Nurjahan N, Perriello G, et al: Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med 333:550-554, 1995
    • (1995) N Engl J Med , vol.333 , pp. 550-554
    • Stumvoll, M.1    Nurjahan, N.2    Perriello, G.3
  • 7
    • 0031657607 scopus 로고    scopus 로고
    • Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus
    • Serrano Rios M: Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus. Eur J Clin Invest 28:14-18, 1998 (suppl 2)
    • (1998) Eur J Clin Invest , vol.28 , Issue.2 SUPPL. , pp. 14-18
    • Serrano Rios, M.1
  • 8
    • 0027082775 scopus 로고
    • Risk of obesity in type II diabetes mellitus
    • Berger M: Risk of obesity in type II diabetes mellitus. Int J Obes Relat Metab Disord 4:S29-S33, 1992 (suppl)
    • (1992) Int J Obes Relat Metab Disord , vol.4 , Issue.SUPPL.
    • Berger, M.1
  • 9
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
    • Speigelman BM: PPAR-γ: Adipogenic regulator and thiazolidinedione receptor. Diabetes 47:507-514, 1998
    • (1998) Diabetes , vol.47 , pp. 507-514
    • Speigelman, B.M.1
  • 10
    • 0029977518 scopus 로고    scopus 로고
    • A human peroxisome-proliferator-activated receptor-γ is activated by inducers of adipogenesis, including thiazolidinedione drugs
    • Lambe KG, Tugwood JD: A human peroxisome-proliferator-activated receptor-γ is activated by inducers of adipogenesis, including thiazolidinedione drugs. Eur J Biochem 239:1-7, 1996
    • (1996) Eur J Biochem , vol.239 , pp. 1-7
    • Lambe, K.G.1    Tugwood, J.D.2
  • 11
    • 0031720840 scopus 로고    scopus 로고
    • YM268 increases the glucose uptake, cell differentiation, and mRNA expression of glucose transporter in 3T3-L1 adipocytes
    • Shimaya A, Kurosaki E, Shioduka K, et al: YM268 increases the glucose uptake, cell differentiation, and mRNA expression of glucose transporter in 3T3-L1 adipocytes. Horm Metab Res 30:543-548, 1998
    • (1998) Horm Metab Res , vol.30 , pp. 543-548
    • Shimaya, A.1    Kurosaki, E.2    Shioduka, K.3
  • 12
    • 0031437981 scopus 로고    scopus 로고
    • Insulin sensitizer YM268 ameliorates insulin resistance by normalizing the decreased content of GLUT4 in adipose tissue of obese Zucker rats
    • Shimaya A, Noshiro O, Hirayama R, et al: Insulin sensitizer YM268 ameliorates insulin resistance by normalizing the decreased content of GLUT4 in adipose tissue of obese Zucker rats. Eur J Endocrinol 137:693-700, 1997
    • (1997) Eur J Endocrinol , vol.137 , pp. 693-700
    • Shimaya, A.1    Noshiro, O.2    Hirayama, R.3
  • 13
    • 0031018421 scopus 로고    scopus 로고
    • Role of plasma insulin concentration in regulating glucose and lipid metabolism in lean and obese Zucker rats
    • Noshiro O, Hirayama R, Shimaya A, et al: Role of plasma insulin concentration in regulating glucose and lipid metabolism in lean and obese Zucker rats. Int J Obes Relat Metab Disord 21:115-121, 1997
    • (1997) Int J Obes Relat Metab Disord , vol.21 , pp. 115-121
    • Noshiro, O.1    Hirayama, R.2    Shimaya, A.3
  • 14
    • 1842279106 scopus 로고
    • Expression of specific mRNA during adipose differentiation: Identification of an mRNA encoding a homologue of myelin P2 protein
    • Bemlohr DA, Angus CW, Lane MD, et al: Expression of specific mRNA during adipose differentiation: Identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci USA 81:5468-5472, 1984
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5468-5472
    • Bemlohr, D.A.1    Angus, C.W.2    Lane, M.D.3
  • 15
    • 0027460648 scopus 로고
    • Regulated expression of an insulin-responsive glucose transporter (GLUT4) minigene in 3T3-L1 adipocytes and transgenic mice
    • Ezaki O, Flores-Riveros JR, Kaestner KH, et al: Regulated expression of an insulin-responsive glucose transporter (GLUT4) minigene in 3T3-L1 adipocytes and transgenic mice. Proc Natl Acad Sci USA 90:3348-3352, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3348-3352
    • Ezaki, O.1    Flores-Riveros, J.R.2    Kaestner, K.H.3
  • 16
    • 0015902527 scopus 로고
    • Effect of cell chromosome number on simian virus 40 replication
    • Robb JA, Huebner K: Effect of cell chromosome number on simian virus 40 replication. Exp Cell Res 81:120-126, 1973
    • (1973) Exp Cell Res , vol.81 , pp. 120-126
    • Robb, J.A.1    Huebner, K.2
  • 17
    • 0028321529 scopus 로고
    • Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
    • Kliewer SA, Forman BM, Blumberg B, et al: Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci US A 91:7355-7359, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7355-7359
    • Kliewer, S.A.1    Forman, B.M.2    Blumberg, B.3
  • 18
    • 0028886694 scopus 로고
    • Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
    • Kato S, Endoh H, Masuhiro Y, et al: Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270:1491-1494, 1995
    • (1995) Science , vol.270 , pp. 1491-1494
    • Kato, S.1    Endoh, H.2    Masuhiro, Y.3
  • 19
    • 0022483765 scopus 로고
    • Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice
    • Prochazka M, Premdas FH, Leiter EH, et al: Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice. Diabetes 35:725-728, 1986
    • (1986) Diabetes , vol.35 , pp. 725-728
    • Prochazka, M.1    Premdas, F.H.2    Leiter, E.H.3
  • 20
    • 0014805928 scopus 로고
    • Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets
    • Like AA, Chick WL: Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets. Diabetologia 6:207-215, 1970
    • (1970) Diabetologia , vol.6 , pp. 207-215
    • Like, A.A.1    Chick, W.L.2
  • 21
    • 0025938575 scopus 로고
    • Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/sJ-db/db mice
    • Fujiwara T, Wada M, Fukuda K, et al: Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/sJ-db/db mice. Metabolism 40:1213-1218, 1991
    • (1991) Metabolism , vol.40 , pp. 1213-1218
    • Fujiwara, T.1    Wada, M.2    Fukuda, K.3
  • 22
    • 0021244284 scopus 로고
    • Ciglitazone, a new hypoglycemic agent. IV. Effect on pancreatic islets of C57BL/6J-ob/ob and C57BL/KsJ-db/db mice
    • Diani AR, Peterson T, Sawada GA, et al: Ciglitazone, a new hypoglycemic agent. IV. Effect on pancreatic islets of C57BL/6J-ob/ob and C57BL/KsJ-db/db mice. Diabetologia 27:225-234, 1984
    • (1984) Diabetologia , vol.27 , pp. 225-234
    • Diani, A.R.1    Peterson, T.2    Sawada, G.A.3
  • 23
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ)
    • Lehmann JM, Moore LB, Smith-Oliver TA, et al: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ). J Biol Chem 270:12953-12956, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3
  • 24
    • 14444281382 scopus 로고    scopus 로고
    • Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma
    • Young PW, Buckle DR, Cantello BC, et al: Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma. J Pharmacol Exp Ther 284:751-759, 1998
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 751-759
    • Young, P.W.1    Buckle, D.R.2    Cantello, B.C.3
  • 25
    • 0027524987 scopus 로고
    • Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus
    • Rebuffé-Scrive M, Surwit R, Feinglos M, et al: Regional fat distribution and metabolism in a new mouse model (C57BL/6J) of non-insulin-dependent diabetes mellitus. Metabolism 42:1405-1409, 1993
    • (1993) Metabolism , vol.42 , pp. 1405-1409
    • Rebuffé-Scrive, M.1    Surwit, R.2    Feinglos, M.3
  • 26
    • 0018144330 scopus 로고
    • Evidence for a single locus controlling susceptibility to virus-induced diabetes mellitus
    • Onodera T, Yoon JW, Brown KS, et al: Evidence for a single locus controlling susceptibility to virus-induced diabetes mellitus. Nature 274:693-696, 1978
    • (1978) Nature , vol.274 , pp. 693-696
    • Onodera, T.1    Yoon, J.W.2    Brown, K.S.3
  • 27
    • 0030027918 scopus 로고    scopus 로고
    • Insulin resistance and body fat distribution
    • Yamashita S, Nakamura T, Shimomura I, et al: Insulin resistance and body fat distribution. Diabetes Care 19:287-291, 1996
    • (1996) Diabetes Care , vol.19 , pp. 287-291
    • Yamashita, S.1    Nakamura, T.2    Shimomura, I.3
  • 28
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
    • Okuno A, Tamemoto H, Tobe K, et al: Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest 101:1354-1361, 1998
    • (1998) J Clin Invest , vol.101 , pp. 1354-1361
    • Okuno, A.1    Tamemoto, H.2    Tobe, K.3
  • 29
    • 15444347751 scopus 로고    scopus 로고
    • Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rats
    • Hallakou S, Doaré L, Foufelle F, et al: Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rats. Diabetes 46:1393-1399, 1997
    • (1997) Diabetes , vol.46 , pp. 1393-1399
    • Hallakou, S.1    Doaré, L.2    Foufelle, F.3
  • 30
    • 0027080932 scopus 로고
    • Adipocyte fatty acid - Binding protein: Regulation of gene expression in vivo and in vitro by an insulin-sensitizing agent
    • Kletzien RF, Foellmi LA, Harris PKW, et al: Adipocyte fatty acid - binding protein: Regulation of gene expression in vivo and in vitro by an insulin-sensitizing agent. Mol Pharmacol 42:558-562, 1992
    • (1992) Mol Pharmacol , vol.42 , pp. 558-562
    • Kletzien, R.F.1    Foellmi, L.A.2    Harris, P.K.W.3
  • 31
    • 0032484224 scopus 로고    scopus 로고
    • A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties
    • Reginato MJ, Bailey ST, Krakow SI, et al: A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties. J Biol Chem 273:32679-32684, 1998
    • (1998) J Biol Chem , vol.273 , pp. 32679-32684
    • Reginato, M.J.1    Bailey, S.T.2    Krakow, S.I.3
  • 32
    • 0031800882 scopus 로고    scopus 로고
    • Development of infrared imaging to measure thermogenesis in cell culture: Thermogenic effects of uncoupling protein-2, troglitazone, and β-adrenoceptor agents
    • Paulik MA, Buckholz RG, Lancaster ME, et al: Development of infrared imaging to measure thermogenesis in cell culture: Thermogenic effects of uncoupling protein-2, troglitazone, and β-adrenoceptor agents. Pharm Res 6:944-949, 1998
    • (1998) Pharm Res , vol.6 , pp. 944-949
    • Paulik, M.A.1    Buckholz, R.G.2    Lancaster, M.E.3
  • 33
    • 0031985802 scopus 로고    scopus 로고
    • Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes
    • Digby JE, Montague CT, Sewter CP, et al: Thiazolidinedione exposure increases the expression of uncoupling protein 1 in cultured human preadipocytes. Diabetes 47:138-141, 1998
    • (1998) Diabetes , vol.47 , pp. 138-141
    • Digby, J.E.1    Montague, C.T.2    Sewter, C.P.3
  • 34
    • 0032500802 scopus 로고    scopus 로고
    • In vivo effects of pioglitazone on uncoupling protein-2 and -3 mRNA levels in skeletal muscle of hyperglycemic KK mice
    • Shimokawa T, Kato M, Watanabe Y, et al: In vivo effects of pioglitazone on uncoupling protein-2 and -3 mRNA levels in skeletal muscle of hyperglycemic KK mice. Biochem Biophys Res Commun 251:374-378, 1998
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 374-378
    • Shimokawa, T.1    Kato, M.2    Watanabe, Y.3
  • 35
    • 0030582447 scopus 로고    scopus 로고
    • Induction of uncoupling protein in brown adipose tissue: Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent
    • Foellmi-Adams LA, Wyse BM, Herron D, et al: Induction of uncoupling protein in brown adipose tissue: Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent. Biochem Pharmacol 52:693-701, 1996
    • (1996) Biochem Pharmacol , vol.52 , pp. 693-701
    • Foellmi-Adams, L.A.1    Wyse, B.M.2    Herron, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.