Protein-polymer nano-machines. Toward synthetic control of biological processes

Journal of Nanobiotechnology

Volumn 2, Issue , 2004, Pages

  Pennadam, Sivanand S ^a   Firman, Keith ^a   Alexander, Cameron ^a   Górecki, Dariusz C ^a  

^a UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIALS; BIOTECHNOLOGY; CELLS; ENZYMES; PHASE TRANSITIONS; POLYMERS;

BIOLOGICAL MEDIA; BIOLOGICAL PROCESSES; MOLECULAR MOTORS; MOLECULAR SWITCHES; NANO-SCALE MACHINES;

NANOTECHNOLOGY;

COPOLYMER; DNA METHYLTRANSFERASE; NANOPARTICLE; POLY(N ISOPROPYLACRYLAMIDE); POLYMER;

CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; CONJUGATION; DEVICE; DNA CLEAVAGE; ENERGY RESOURCE; EQUIPMENT DESIGN; GENE TRANSLOCATION; MOLECULAR BIOLOGY; MOTOR PERFORMANCE; NANOTECHNOLOGY; PHASE TRANSITION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SYNTHESIS; TEMPERATURE DEPENDENCE;

EID: 13644256398     PISSN: 14773155     EISSN: None     Source Type: Journal    
DOI: 10.1186/1477-3155-2-8     Document Type: Review

References (54)

1. Ishii Y, Ishijima A, Yanagida T: Single molecule nanomanipulation of biomolecules. Trends in Biotechnology 2001, 19:211-216.
2. Wang MD: Manipulation of single molecules in biology. Current Opinions in Biotechnology 1999, 10:81-86.
3. Badjic JD, Balzani V, Credi A, Silvi S, Stoddart JF: A Molecular Elevator. Science 2004, 303:1845-1849.
4. Firman K, Dutta C, Weiserova M, Janscak P: The role of subunit assembly in the functional control of type I restriction-modification enzymes. Molecular Biology Today 2000, 1:1-8.
5. Murray NE: Type I restriction systems: sophisticated molecular machines (a legacy of Bertani and Weigle). Microbiology and Molecular Biology Reviews 2000, 64:412-434.
6. Barcus VA, Titheradge AJB, Murray NE: The diversity of alleles at the hsd locus in natural populations of Escherichia coli. Genetics 1995, 140:1187-1197.
7. Lee NS, Rutebuka O, Arakawa T, Bickle TA, Ryu J: KpnAI, a new type I restriction-modification system in Klebsiella pneumoniae. J Mol Biol 1997, 271:342-8.
8. Titheradge AJB, Ternent D, Murray NE: A third family of allelic hsd genes in Salmonella enterica: sequence comparisons with related proteins identify conserved regions implicated in restriction of DNA. Mol Microbiol 1996, 22:437-447.
9. Price C, Shepherd JCW, Bickle TA: DNA recognition by a new family of type I restriction enzymes: a unique relationship between two different DNA specificities. European Molecular Biology Organisation Journal 1987, 6:1493-1498.
10. Dryden DTF, Davies GD, Martin I, Powell LM, Murray NE, Ellis DJ, Berge T, Edwardson JM, Henderson RM: The assembly of the Eco KI type I DNA restriction/modification enzyme and its interaction with DNA. Biochem Soc Trans 1999, 27:691-696.
11. Janscák P, Dryden D, Firman K: Analysis of the subunit assembly of the type IC restriction-modification enzyme Eco R124I. Nucleic Acids Res 1998, 26:4439-4445.
12. Firman K, Szczelkun M: Measuring motion on DNA by the type I restriction endonuclease Eco R124I using triplex dissociation. European Molecular Biology Organisation Journal 2000, 19: 094-2102.
13. Dryden DTF, Cooper LP, Murray NE: Purification and characterisation of the methyltransferase from the type I restriction and modification system of Escherichia coli K12. J Biol Chem 1993, 268:13228-13236.
14. Taylor I, Patel J, Firman K, Kneale GG: Purification and biochemical characterisation of the Eco R124 modification methylase. Nucleic Acids Res 1992, 20:179-186.
15. Davies GP, Powell LM, Webb JL, Cooper LP, Murray NE: Eco KI with an amino acid substitution in any one of seven DEADbox motifs has impaired ATPase and endonuclease activities. Nucleic Acids Res 1998, 26:4828-36.
16. Davies GP, Kemp P, Molineux IJ, Murray NE: The DNA translocation and ATPase activities of restriction-deficient mutants of Eco KI. J Mol Biol 1999, 292:787-796.
17. Gorbalenya AE, Koonin EV: Endonuclease (R) subunits of type I and type III restriction-modification enzymes contain a helicase-like domain. FEBS Letts 1991, 291:277-281.
18. Murray NE, Daniel AS, Cowan GM, Sharp PM: Conservation of motifs within the unusually variable polypeptide sequences of type I restriction and modification enzymes. Mol Microbiol 1993, 9: 33-143.
19. Cooper LP, Dryden DTF: The domains of a type I DNA methyltransferase. Interactions and role in recognition of DNA methylation. J Mol Biol 1994, 236:1011-1021.
20. Szczelkun MD, Dillingham MS, Janscák P, Firman K, Halford SE: Repercussions of DNA tracking by the type IC restriction endonuclease Eco R124I on linear, circular and catenated substrates. European Molecular Biology Organisation Journal 1996, 15:6335-6347.
21. Studier FW, Bandyopadhyay PK: Model for how type I restriction enzymes select cleavage sites in DNA. Proceedings of the National Academy of Sciences USA 1988, 85:4677-4681.
22. Szczelkun MD, Janscák P, Firman K, Halford SE: Selection of non-specific DNA cleavage sites by the type IC restriction endonuclease Eco R124I. J Mol Biol 1997, 271: 12-123.
23. Linder P, Doelz R, Gubler M, Bickle TA: An anticodon nuclease gene inserted into a hsd region encoding a type I DNA restriction system. Nucleic Acids Res 1990, 18:7170.
24. Tyndall C, Lehnherr H, Sandmeier U, Kulik E, Bickle TA: The type IC hsd loci of the enterobacteria are flanked by DNA with high homology to the phage P1 genome: implications for the evolution and spread of DNA restriction systems. Mol Microbiol 1997, 23: 29-736.
25. Tyndall C, Meister J, Bickle TA: The Escherichia coli prr region encodes a functional type IC DNA restriction system closely integrated with an anticodon nuclease gene. J Mol Biol 1994, 237:266-274.
26. Price C, Bickle TA: A possible role for restriction in bacterial evolution. Micro Sci 1986, 3:296-299.
27. Bickle TA, Krüger DH: Biology of DNA restriction. Microbiological Reviews 1993, 57:434-450.
28. Holubová I, Janscák P, Weiserová M, Benada O, Hubácek J, Firman K: Cellular localisation of the type I restriction and modification system of Escherichia coli K-12. 1994:A76.
29. Holubová I, Vejsadová S, Weiserová M, Firman K: Localisation of the type I restriction-modification enzyme Eco KI in the bacterial cell. Biochem Biophys Res Commun 2000, 270: 6-51.
30. Barker SLR, Ross D, Tarlov MJ, Gaitan M, Locascio LE: Control of Flow Direction in Microfluidic Devices With Polyelectrolyte Multilayers. Anal Chem 2000, 72:5925-5929.
31. Kikuchi A, Okano T: Pulsatile drug release control using hydrogels. Advanced Drug Delivery Reviews 2002, 54:53-77.
32. Li SK, D'emanuele A: On-Off Transport Through a Thermoresponsive Hydrogel Composite Membrane. J Controlled Release 2001, 75:55-67.
33. Kost J, Langer R: Responsive Polymeric Delivery Systems. Advanced Drug Delivery Reviews 2001, 46:125-148.
34. Peppas N: Hydrogels and drug delivery. Current Opinion In Colloid & Interface Science 1997, 2:531-537.
35. Ista LK, Lopez GP: Lower critical solubility temperature materials as biofouling release agents. J Indust Microbiol Biotechnol 1998, 20:121-125.
36. Cunliffe D, Alarcon CD, Peters V, Smith JR, Alexander C: Thermoresponsive Surface-Grafted Poly(N-Isopropylacrylamide) Copolymers: Effect of Phase Transitions on Protein and Bacterial Attachment. Langmuir 2003, 19:2888-2899.
37. Kwon OH, Kikuchi A, Yamato M, Okano T: Accelerated Cell Sheet Recovery by Co-Grafting of Peg With Pipaam Onto Porous Cell Culture Membranes. Biomaterials 2003, 24:1223-1232.
38. Yamato M, Konno C, Utsumi M, Kikuchi A, Okano T: Thermally responsive polymer-grafted surfaces facilitate patterned cell seeding and co-culture. Biomaterials 2002, 23:561-567.
39. Raucher D, Chilkoti A: Enhanced Uptake of a Thermally Responsive Polypeptide by Tumor Cells in Response to Its Hyperthermia-Mediated Phase Transition. Cancer Res 2001, 61: 163-7170.
40. Hoffmann J, Plotner M, Kuckling D, Fischer WJ: Photopatterning of Thermally Sensitive Hydrogels Useful for Microactuators. Sensors and Actuators a-Physical 1999, 77: 39-144.
41. Szczubialka K, Jankowska M, Nowakowska M: "Smart" Polymeric Nanospheres as New Materials for Possible Biomedical Applications. Journal of Materials Science-Materials in Medicine 2003, 14:699-703.
42. Schild HG: Poly(N-Isopropylacrylamide): experiment, theory and application. Prog Polym Sci 1992, 17:163-249.
43. Caliceti P, Veronese FM: Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates. Advanced Drug Delivery Reviews 2003, 55:1261-1277.
44. Youngster S, Wang YS, Grace M, Bausch J, Bordens R, Wyss DF: Structure, Biology, and Therapeutic Implications of Pegylated Interferon Alpha-2b. Current Pharmaceutical Design 2002, 8: 139-2157.
45. Maeda H: Smancs and Polymer-Conjugated Macromolecular Drugs: Advantages in Cancer Chemotherapy. Advanced Drug Delivery Reviews 2001, 46:169-185.
46. Ulbrich K, Strohalm J, Subr V, Plocova D, Duncan R, Rihova B: Polymeric Conjugates of Drugs and Antibodies for Site-Specific Drug Delivery. Macromolecular Symposia 1996, 103:177-192.
47. Omelyanenko V, Kopeckova P, Gentry C, Shiah JG, Kopecek J: Hpma Copolymer-Anticancer Drug-Ov-Tl16 Antibody Conjugates .1. Influence of the Method of Synthesis on the Binding Affinity to Ovcar-3 Ovarian Carcinoma Cells in Vitro. Journal of Drug Targeting 1996, 3 : 57-373.
48. Duncan R, Spreafico F: Polymer Conjugates - Pharmacokinetic Considerations for Design and Development. Clinical Pharmacokinetics 1994, 27:290-306.
49. Chilkoti A, Chen GH, Stayton PS, Hoffman AS: Site-Specific Conjugation of a Temperature-Sensitive Polymer to a Genetically-Engineered Protein. Bioconjugate Chemistry 1994, 5:504-507.
50. Hoffman AS: Bioconjugates of Intelligent Polymers and Recognition Proteins for Use in Diagnostics and Affinity Separations. Clinical Chemistry 2000, 46:1478-1486.
51. Shimoboji T, Larenas E, Fowler T, Hoffman AS, Stayton PS: Temperature-Induced Switching of Enzyme Activity With Smart Polymer-Enzyme Conjugates. Bioconjugate Chemistry 2003, 14: 17-525.
52. Shimoboji T, Larenas E, Fowler T, Kulkarni S, Hoffman AS, Stayton PS: Photoresponsive Polymer-Enzyme Switches. Proceedings of the National Academy of Sciences USA 2002, 99:16592-16596.
53. Pennadam SS, Lavigne M, Firman K, Mernagh D, Alexander C, Górecki DC: A molecular motor controlled by a thermoresponsive polymer switch. 6th International Symposium on Polymer Therapeutics 2004:A52.
54. Pennadam SS, Lavigne M, Dutta CF, Firman K, Mernagh D, Górecki DC, Alexander C: Control of a multi-subunit DNA motor by a thermo responsive polymer switch. JACS 2004 in press.