Plasmacytoid precursor dendritic cells facilitate allogeneic hematopoietic stem cell engraftment

Journal of Experimental Medicine

Volumn 201, Issue 3, 2005, Pages 373-383

  Fugier Vivier, Isabelle J ^a,b   Rezzoug, Francine ^a   Huang, Yiming ^a   Graul Layman, Amanda J ^a   Schanie, Carrie L ^a   Xu, Hong ^a   Chilton, Paula M ^a   Ildstad, Suzanne T ^a  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; FLT3 LIGAND; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ARTICLE; CELL MATURATION; CELL SUBPOPULATION; CHIMERA; CONTROLLED STUDY; DENDRITIC CELL; GRAFT VERSUS HOST REACTION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SKIN ALLOGRAFT;

ANIMALS; ANTIGENS, CD11C; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CYTOKINES; DENDRITIC CELLS; DNA; FLOW CYTOMETRY; GRAFT SURVIVAL; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED STRAINS; PLASMA CELLS; STEM CELLS; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS;

EID: 13644256027     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041399     Document Type: Article

References (50)

1. Ildstad, S.T., and D.H. Sachs. 1984. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature. 307:168-170.
2. Billingham, R.E., L. Brent, and P.B. Medawar. 1953. Actively acquired tolerance to foreign cells. Nature. 172:603-607.
3. Lu, L., R.N. Shen, and H.E. Broxmeyer. 1996. Stem cells from bone marrow, umbilical cord blood and peripheral blood for clinical application: current status and future application. Crit. Rev. Oncol. Hematol. 22:61-78.
4. Korbling, M., and P. Anderlini. 2001. Peripheral blood stem cell versus bone marrow allotransplantation: does the source of hematopoietic stem cells matter? Blood. 98:2900-2908.
5. Champlin, R. 1990. T-cell depletion to prevent graft-versus-host disease after bone marrow transplantation. Hematol. Oncol. Clin. North Am. 4:687-698.
6. Blazar, B.R., A.M. Filipovich, J.H. Kersey, F.M. Uckun, N.C. Ramsay, P.B. McGlave, and D.A. Vallera. 1987. T-cell depletion of donor marrow grafts: Effects on graft-versus-host disease and engraftment. Wiley-Liss, New York, NY, 381 pp.
7. Drobyski, W., R. Ash, J.T. Casper, T. McAuliffe, M.M. Horowitz, C. Lawton, C. Keever, L.A. Baxter-Lowe, B. Camitta, F. Garbrecht, et al. 1994. Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia. Blood. 83:1980-1987.
8. - cells in whole bone marrow facilitate the engraftment of hematopoietic stem cells across allogeneic barriers. Immunity. 11:579-590.
9. Kaufman, C.L., Y.L. Colson, S.M. Wren, S.L. Watkins, R.L. Simmons, and S.T. Ildstad. 1994. Phenotypic characterization of a novel bone-marrow derived cell that facilitates engraftment of allogeneic bone marrow stem cells. Blood. 84:2436-2446.
10. Colson, Y.L., K. Christopher, J. Glickman, K.N. Taylor, R. Wright, and D.L. Perkins. 2004. Absence of clinical gvhd and the in vivo induction of regulatory t cells following facilitating cell transplantation. Blood. 104:3829-3835.
11. Grimes, H.L., C.L. Schanie, Y. Huang, D. Cramer, F. Rezzoug, I. Fugier-Vivier, and S.T. Ildstad. 2004. Graft facilitating cells are derived from hematopoietic stem cells and functionally require CD3, but are distinct from T lymphocytes. Exp. Hematol. 32:946-954.
12. Morelli, A.E., H. Hackstein, and A.W. Thomson. 2001. Potential of tolerogenic dendritic cells for transplantation. Semin. Immunol. 13:323-335.
13. Thomson, A.W., and L. Lu. 1999. Dendritic cells as regulators of immune reactivity: implications for transplantation. Transplantation. 68:1-8.
14. Guermonprez, P., J. Valladeau, L. Zitvogel, C. Thery, and S. Amigorena. 2002. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20:621-667.
15. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y.J. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18:767-811.
16. Liu, Y.J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell. 106:259-262.
17. Shortman, K., and W.R. Heath. 2001. Immunity or tolerance? That is the question for dendritic cells. Nat. Immunol. 2:988-989.
18. Kalinski, P., C.M. Hilkens, E.A. Wierenga, and M.L. Kapsenberg. 1999. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal. Immunol. Today. 20:561-567.
19. Boonstra, A., C. Asselin-Paturel, M. Gilliet, C. Crain, G. Trinchieri, Y.J. Liu, and A. O'Garra. 2003. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J. Exp. Med. 197:101-109.
20. Arpinati, M., C.L. Green, S. Heimfeld, J.E. Heuser, and C. Anasetti. 2000. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood. 95:2484-2490.
21. Rossi, M., M. Arpinati, D. Rondelli, and C. Anasetti. 2002. Plasmacytoid dendritic cells: do they have a role in immune responses after hematopoietic cell transplantation? Hum. Immunol. 63:1194-1200.
22. Liu, Y.J., and B. Blom. 2000. Introduction: TH2-inducing DC2 for immunotherapy. Blood. 95:2482-2483.
23. Siegal, F.P., N. Kadowaki, M. Shodell, P.A. Fitzgerald-Bocarsly, K. Shah, S. Ho, S. Antonenko, and Y.J. Liu. 1999. The nature of the principal type 1 interferon-producing cells in human blood. Science. 284:1835-1837.
24. Asselin-Paturel, C., A. Boonstra, M. Dalod, I. Durand, N. Yessaad, C. Dezutter-Dambuyant, A. Vicari, A. O'Garra, C. Biron, F. Briere, and G. Trinchieri. 2001. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2:1144-1150.
25. Bjorck, P. 2001. Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice. Blood. 98:3520-3526.
26. Fonteneau, J.F., M. Gilliet, M. Larsson, I. Dasilva, C. Munz, Y.J. Liu, and N. Bhardwaj. 2003. Activation of influenza virus-specific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity. Blood. 101:3520-3526.
27. Kadowaki, N., S. Antonenko, J.Y. Lau, and Y.J. Liu. 2000. Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J. Exp. Med. 192:219-226.
28. Gilliet, M., A. Boonstra, C. Paturel, S. Antonenko, X.L. Xu, G. Trinchieri, A. O'Garra, and Y.J. Liu. 2002. The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 195:953-958.
29. Brawand, P., D.R. Fitzpatrick, B.W. Greenfield, K. Brasel, C.R. Maliszewski, and T. De Smedt. 2002. Murine plasmacytoid pre-dendritic cells generated from Flt3 ligand-supplemented bone marrow cultures are immature APCs. J. Immunol. 169:6711-6719.
30. + dendritic cells only after microbial stimulus. J. Exp. Med. 196:1307-1319.
31. Martin, P., G.M. Del Hoyo, F. Anjuere, C.F. Arias, H.H. Vargas, L. Fernandez, V. Parrillas, and C. Ardavin. 2002. Characterization of a new subpopulation of mouse CD8alpha(+) B220(+) dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential. Blood. 100:383-390.
32. Maraskovsky, E., K. Brasel, M. Teepe, E.R. Roux, S.D. Lyman, K. Shortman, and H.J. McKenna. 1996. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J. Exp. Med. 184:1953-1962.
33. Neipp, M., T. Zorina, M.A. Domenick, B.G. Exner, and S.T. Ildstad. 1998. Effect of FLT3 ligand and granulocyte colony-stimulating factor on expansion and mobilization of facilitating cells and hematopoietic stem cells in mice: kinetics and repopulating potential. Blood. 92:3177-3188.
34. Bilsborough, J., T.C. George, A. Norment, and J.L. Viney. 2003. Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties. Immunology. 108:481-492.
35. Nikolic, T., G.M. Dingjan, P.J. Leenen, and R.W. Hendriks. 2002. A subfraction of B220(+) cells in murine bone marrow and spleen does not belong to the B cell lineage but has dendritic cell characteristics. Eur. J. Immunol. 32:686-692.
36. Hochrein, H., M. O'Keeffe, and H. Wagner. 2002. Human and mouse plasmacytoid dendritic cells. Hum. Immunol. 63:1103-1110.
37. Kuwana, M., J. Kaburaki, T.M. Wright, Y. Kawakami, and Y. Ikeda. 2001. Induction of antigen-specific human CD4(+) T cell anergy by peripheral blood DC2 precursors. Eur. J. Immunol. 31:2547-2557.
38. Rissoan, M.C., V. Soumelis, N. Kadowaki, G. Grouard, F. Briere, M.R. de Waal, and Y.J. Liu. 1999. Reciprocal control of T helper cell and dendritic cell differentiation. Science. 283:1183-1186.
39. Kuwana, M. 2002. Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets. Hum. Immunol. 63:1156-1163.
40. de Heer, H.J., H. Hammad, T. Soullie, D. Hijdra, N. Vos, M. Willart, H. Hoogsteden, and N. Lambrecht. 2004. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 200:89-98.
41. Moore, K.W., M.R. de Waal, R.L. Coffman, and A. O'Garra. 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19:683-765.
42. Wakkach, A., N. Foumier, V. Brun, J.P. Breittmayer, F. Cottrez, and H. Groux. 2003. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity. 18:605-617.
43. Wakkach, A., F. Cottrez, and H. Groux. 2001. Differentiation of regulatory T cells 1 is induced by CD2 costimulation. J. Immunol. 167:3107-3113.
44. O'Connell, P.J., W. Li, Z. Wang, S.M. Specht, A.J. Logar, and A.W. Thomson. 2002. Immature and mature CD8alpha+ dendritic cells prolong the survival of vascularized heart allografts. J. Immunol. 168:143-154.
45. Kadowaki, N., S. Antonenko, S. Ho, M.C. Rissoan, V. Soumelis, S.A. Porcelli, L.L. Lanier, and Y.J. Liu. 2001. Distinct cytokine profiles of neonatal natural killer T cells after expansion with subsets of dendritic cells. J. Exp. Med. 193:1221-1226.
46. Colson, Y.L., and S.T. Ildstad. 1997. Characterization of two unique cell surface molecules on the facilitating cell. Surg. Forum. 48:481-484.
47. Schuchert, M.J., R.D. Wright, and Y.L. Colson. 2000. Characterization of a newly discovered T-cell receptor beta-chain heterodimer expressed on a CD8+ bone marrow subpopulation that promotes allogeneic stem cell engraftment. Nat. Med. 6:904-909.
48. Huang, Y., F. Rezzoug, P.M. Chilton, H.L. Grimes, D.E. Cramer, and S.T. Ildstad. 2004. Matching at the MHC class I K locus is essential for long-term engraftment of purified hematopoietic stem cells: a role for host NK cells in regulating HSC engraftment. Blood. 104:873-880.
49. Xu, H., P.M. Chilton, Y. Huang, C.L. Schanie, and S.T. Ildstad. 2004. Production of donor T cells is critical for induction of donor-specific tolerance and maintenance of chimerism. J. Immunol. 172:1463-1471.
50. Billingham, M.E. 1994. Pathology and etiology of chronic rejection of the heart. Clin. Transplant. 8:289-292.