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Volumn 6, Issue 1, 2005, Pages 27-36

Genetic factors in aminoglycoside toxicity

Author keywords

Aminoglycosides; Maternally inherited deafness; Mitochondrial mutations; Ototoxicity; Pharmacogenomics

Indexed keywords

AMINOGLYCOSIDE; EAR DROPS; GENTAMICIN; GLYCOPROTEIN P; IMATINIB; KANAMYCIN; MITOCHONDRIAL RNA; N METHYL DEXTRO ASPARTIC ACID; NEOMYCIN; NEUROTROPHIC FACTOR; NUCLEAR FACTOR; PHOSPHOLIPID; STREPTOMYCIN; TOBRAMYCIN;

EID: 13544261687     PISSN: 14622416     EISSN: None     Source Type: Journal    
DOI: 10.1517/14622416.6.1.27     Document Type: Review
Times cited : (122)

References (89)
  • 1
    • 0000043793 scopus 로고
    • Antimicrobial agents
    • (8th edn). Gilman AG, Rall TW, Nies AS, Taylor P (Eds), Pergamon Press, Inc., Elmsford, NY, USA
    • Sande MA, Mandell GL: Antimicrobial agents. In: The Pharmacological Basis of Therapeutics (8th edn). Gilman AG, Rall TW, Nies AS, Taylor P (Eds), Pergamon Press, Inc., Elmsford, NY, USA 1098-1116 (1990).
    • (1990) The Pharmacological Basis of Therapeutics , pp. 1098-1116
    • Sande, M.A.1    Mandell, G.L.2
  • 3
    • 0022618766 scopus 로고
    • Aminoclycoside research 1975-1985: Prospects for development of improved agents
    • Price KE: Aminoclycoside research 1975-1985: prospects for development of improved agents. Antimicrobial Agents Chemother. 29, 543-548 (1986).
    • (1986) Antimicrobial Agents Chemother. , vol.29 , pp. 543-548
    • Price, K.E.1
  • 4
    • 0016276843 scopus 로고
    • Ototoxicity with children caused by streptomycin
    • Prazic M, Salaj B: Ototoxicity with children caused by streptomycin. Audiology 14, 173-176 (1975).
    • (1975) Audiology , vol.14 , pp. 173-176
    • Prazic, M.1    Salaj, B.2
  • 6
    • 0021365039 scopus 로고
    • Risk factors for the development of auditory toxicity in patients receiving aminoglycosides
    • Moore RD, Smith CR, Lietman PS: Risk factors for the development of auditory toxicity in patients receiving aminoglycosides. J. Infect. Dis. 149, 23-30 (1984).
    • (1984) J. Infect. Dis. , vol.149 , pp. 23-30
    • Moore, R.D.1    Smith, C.R.2    Lietman, P.S.3
  • 7
    • 0000771721 scopus 로고
    • Streptomycin sulfate and dihydrostreptomycin toxicity. Behavioural and histopathologic studies
    • McGee TM, Olszewski J: Streptomycin sulfate and dihydrostreptomycin toxicity. Behavioural and histopathologic studies. Arch. Otolaryngol. 75, 295-311 (1962).
    • (1962) Arch. Otolaryngol. , vol.75 , pp. 295-311
    • McGee, T.M.1    Olszewski, J.2
  • 8
    • 0002945653 scopus 로고
    • Structural damage of the organ of Corti and the vestibular epithelia caused by aminoglycoside antibiotics in the guinea-pig
    • Lerner SA, Matz GJ, Hawkins JE Jr (Eds), Little, Brown & Co., Boston, MA, USA
    • Wersall J: Structural damage of the organ of Corti and the vestibular epithelia caused by aminoglycoside antibiotics in the guinea-pig. In: Aminoglycoside Ototoxicity. Lerner SA, Matz GJ, Hawkins JE Jr (Eds), Little, Brown & Co., Boston, MA, USA 197-214 (1981).
    • (1981) Aminoglycoside Ototoxicity , pp. 197-214
    • Wersall, J.1
  • 9
    • 0023231026 scopus 로고
    • Cochlear neural degeneration without hair cell loss in two patients with aminoglycoside ototoxicity
    • Hinojosa R, Lerner SA. Cochlear neural degeneration without hair cell loss in two patients with aminoglycoside ototoxicity. J. Infect. Dis. 156(3), 449-455 (1987).
    • (1987) J. Infect. Dis. , vol.156 , Issue.3 , pp. 449-455
    • Hinojosa, R.1    Lerner, S.A.2
  • 10
    • 0000782819 scopus 로고
    • Site of action of streptomycin upon inner ear sensory cells
    • Duvall AJ, Wersall J: Site of action of streptomycin upon inner ear sensory cells. Acta Otolaryngol. 57, 581-598 (1964).
    • (1964) Acta Otolaryngol. , vol.57 , pp. 581-598
    • Duvall, A.J.1    Wersall, J.2
  • 11
    • 0016349423 scopus 로고
    • Ototoxicite de la kanamycin au jour le jour. Etude experimentale en microscopie electronique
    • Darrouzet J, Guilhaume A: [Ototoxicite de la kanamycin au jour le jour. Etude experimentale en microscopie electronique.] Rev. Laryngol. Otol. Rhinol. 95, 601-621 (1974).
    • (1974) Rev. Laryngol. Otol. Rhinol. , vol.95 , pp. 601-621
    • Darrouzet, J.1    Guilhaume, A.2
  • 12
  • 13
    • 0017645661 scopus 로고
    • Effects of perilymphatic perfusion with neomycin on the cochlear microphonic potential in the guinea-pig
    • Nuttall AL, Marques DM, Lawrence M: Effects of perilymphatic perfusion with neomycin on the cochlear microphonic potential in the guinea-pig. Acta Otolaryngol. 83, 393-400 (1977).
    • (1977) Acta Otolaryngol. , vol.83 , pp. 393-400
    • Nuttall, A.L.1    Marques, D.M.2    Lawrence, M.3
  • 14
    • 0024535053 scopus 로고
    • Blockage of the transduction channels of hair cells in the bullftog's sacculus by aminoglycoside antibiotics
    • Kroese ABA, Das A, Hudspeth AJ: Blockage of the transduction channels of hair cells in the bullftog's sacculus by aminoglycoside antibiotics. Hear. Res. 37, 203-217 (1989).
    • (1989) Hear. Res. , vol.37 , pp. 203-217
    • Kroese, A.B.A.1    Das, A.2    Hudspeth, A.J.3
  • 15
    • 0023153006 scopus 로고
    • Dose-dependent changes in the rat cochlea following aminoglycoside intoxication. I. Physiological study
    • Puel JL, Lenoir M, Uziel A: Dose-dependent changes in the rat cochlea following aminoglycoside intoxication. I. Physiological study. Hear. Res. 26, 191-197 (1987).
    • (1987) Hear. Res. , vol.26 , pp. 191-197
    • Puel, J.L.1    Lenoir, M.2    Uziel, A.3
  • 16
    • 0013798626 scopus 로고
    • A study of the relative concentrations of antibiotics in the blood, spinal fluid and perilymph in animals
    • Vrabec DP, Cody DT, Ulrich JA: A study of the relative concentrations of antibiotics in the blood, spinal fluid and perilymph in animals. Ann. Otol. Rhinol. Laryngol. 74, 689 (1965).
    • (1965) Ann. Otol. Rhinol. Laryngol. , vol.74 , pp. 689
    • Vrabec, D.P.1    Cody, D.T.2    Ulrich, J.A.3
  • 17
    • 0023918234 scopus 로고
    • Pharmacokinetics of aminoglycoside antibiotics in blood, inner-ear fluids and tissues and their relationship to ototoxicity
    • Henley CM, Schacht J: Pharmacokinetics of aminoglycoside antibiotics in blood, inner-ear fluids and tissues and their relationship to ototoxicity. Audiology 27, 137-146 (1988).
    • (1988) Audiology , vol.27 , pp. 137-146
    • Henley, C.M.1    Schacht, J.2
  • 18
    • 0022640994 scopus 로고
    • A review: Effects of noise and ototoxic drugs at the cellular level in the cochlea
    • Lim DJ: A review: effects of noise and ototoxic drugs at the cellular level in the cochlea. Am. J. Otolaryngol. 7, 73-99 (1986 ).
    • (1986) Am. J. Otolaryngol. , vol.7 , pp. 73-99
    • Lim, D.J.1
  • 20
    • 0023573969 scopus 로고
    • Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells
    • Williams SE, Zenner HP, Schacht J: Three molecular steps of aminoglycoside ototoxicity demonstrated in outer hair cells. Hear. Res. 30, 11-18 (1987).
    • (1987) Hear. Res. , vol.30 , pp. 11-18
    • Williams, S.E.1    Zenner, H.P.2    Schacht, J.3
  • 21
    • 0017659506 scopus 로고
    • Gentamicin-induced changes in RNA content in sensory and ganglionic cells in the hearing organ of the lizard Calotes versicolor: A cytochemical and morphological investigation
    • Jarlstedt J, Bagger-Sjoback D: Gentamicin-induced changes in RNA content in sensory and ganglionic cells in the hearing organ of the lizard Calotes versicolor: a cytochemical and morphological investigation. Acta Otolaryngol 84, 361-369 (1977).
    • (1977) Acta Otolaryngol. , vol.84 , pp. 361-369
    • Jarlstedt, J.1    Bagger-Sjoback, D.2
  • 22
    • 0017621924 scopus 로고
    • Radioactive labelling of phospholipids and proteins by cochlear perfusion in the guinea-pig and the effect of neomycin
    • Stockhorst W, Schacht J: Radioactive labelling of phospholipids and proteins by cochlear perfusion in the guinea-pig and the eff-ect of neomycin. Acta Otolaryngol. 83, 401-409 (1977).
    • (1977) Acta Otolaryngol. , vol.83 , pp. 401-409
    • Stockhorst, W.1    Schacht, J.2
  • 23
    • 0030068133 scopus 로고    scopus 로고
    • Variable efficacy of radical scavengers and iron chelators to attenuate gentamycin ototoxicity in guinea pigs in vivo
    • Song BB, Schacht J: Variable efficacy of radical scavengers and iron chelators to attenuate gentamycin ototoxicity in guinea pigs in vivo. Hear. Res. 94, 87-93 (1996).
    • (1996) Hear. Res. , vol.94 , pp. 87-93
    • Song, B.B.1    Schacht, J.2
  • 24
    • 1842337282 scopus 로고
    • Gene mutations in human haemoglobin: The chemical difference between normal and sickle cell haemoglobin
    • Ingram VM: Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature 180, 326 (1957).
    • (1957) Nature , vol.180 , pp. 326
    • Ingram, V.M.1
  • 25
    • 0021346853 scopus 로고
    • Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
    • Groffen J, Stephenson JR, Heisterkamp N, de Klein A, Bartram CR, Grosveld G: Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 36, 93-99 (1984).
    • (1984) Cell , vol.36 , pp. 93-99
    • Groffen, J.1    Stephenson, J.R.2    Heisterkamp, N.3    de Klein, A.4    Bartram, C.R.5    Grosveld, G.6
  • 26
    • 0025043959 scopus 로고
    • The t(15;17) translocation of acute promyelocytic leukemia fuses the retinoic acid receptor α gene to a novel transcribed locus
    • de The H, Chomienne C, Lanotte M, Degos L, Dejean A. The t(15;17) translocation of acute promyelocytic leukemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature 347, 558-561 (1990).
    • (1990) Nature , vol.347 , pp. 558-561
    • de The, H.1    Chomienne, C.2    Lanotte, M.3    Degos, L.4    Dejean, A.5
  • 27
    • 0025201879 scopus 로고
    • All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results
    • Castaigne S, Chomienne C, Daniel MT et al.: All- trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood 76, 1704-1709 (1990).
    • (1990) Blood , vol.76 , pp. 1704-1709
    • Castaigne, S.1    Chomienne, C.2    Daniel, M.T.3
  • 28
    • 0037672877 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive leukaemias: From basic mechanisms to molecular therapeutics
    • Kurzrock R, Kantarjian HM, Druker BJ, Talpaz M: Philadelphia chromosome-positive leukaemias: from basic mechanisms to molecular therapeutics. Ann. Internal Med. 138, 819-830 (2003).
    • (2003) Ann. Internal Med. , vol.138 , pp. 819-830
    • Kurzrock, R.1    Kantarjian, H.M.2    Druker, B.J.3    Talpaz, M.4
  • 29
    • 0001447272 scopus 로고
    • Ototoxicity
    • (3rd edn). Paparella WM, Shumrick DA, Gluckman JL, Meyerhoff WL (Eds), W.B. Saunders Co., Philadelphia, PA, USA
    • Stringer SP, Meyerhoff WL, Wright CG: Ototoxicity. In: Otolaryngology (3rd edn). Paparella WM, Shumrick DA, Gluckman JL, Meyerhoff WL (Eds), W.B. Saunders Co., Philadelphia, PA, USA 1653-1669 (1991).
    • (1991) Otolaryngology , pp. 1653-1669
    • Stringer, S.P.1    Meyerhoff, W.L.2    Wright, C.G.3
  • 30
    • 0024360825 scopus 로고
    • Unique inheritance of streptomycin-induced deafness
    • Higashi K: Unique inheritance of streptomycin-induced deafness. Clin. Genet. 35, 433-436 (1989).
    • (1989) Clin. Genet. , vol.35 , pp. 433-436
    • Higashi, K.1
  • 32
    • 0015120431 scopus 로고
    • Familial incidence of streptomycin hearing loss and hereditary weakness of the cochlea
    • Tsuiki T, Murai S: Familial incidence of streptomycin hearing loss and hereditary weakness of the cochlea. Audiology 10, 315-322 (1971).
    • (1971) Audiology , vol.10 , pp. 315-322
    • Tsuiki, T.1    Murai, S.2
  • 34
    • 0025980075 scopus 로고
    • Genetic aspects of antibiotic induced deafness: Mitochondrial inheritance
    • Hu D-N, Qiu W-Q, Wu B-T et al.: Genetic aspects of antibiotic induced deafness: mitochondrial inheritance. J. Med. Genet. 28, 79-83 (1991).
    • (1991) J. Med. Genet. , vol.28 , pp. 79-83
    • Hu, D.-N.1    Qiu, W.-Q.2    Wu, B.-T.3
  • 35
    • 0002520417 scopus 로고
    • Animal models in the study of ototoxic hearing loss
    • Lerner SA, Matz GL, Hawkins JE Jr (Eds), Little, Brown and Co., Boston, MA, USA
    • Stebbins WC, McGinn CS, Feitosa AG et al.: Animal models in the study of ototoxic hearing loss. In: Aminoglycoside Ototoxicity. Lerner SA, Matz GL, Hawkins JE Jr (Eds), Little, Brown and Co., Boston, MA, USA, 5-25 (1981).
    • (1981) Aminoglycoside Ototoxicity , pp. 5-25
    • Stebbins, W.C.1    McGinn, C.S.2    Feitosa, A.G.3
  • 36
    • 0023579725 scopus 로고
    • Decoding at the ribosomal A site: Antibiotics, misreading and energy of aminoacyl-tRNA binding
    • Hornig H, Woolley P, Luhrmann R. Decoding at the ribosomal A site: antibiotics, misreading and energy of aminoacyl-tRNA binding. Biochimie 69, 803-813 (1987).
    • (1987) Biochimie , vol.69 , pp. 803-813
    • Hornig, H.1    Woolley, P.2    Luhrmann, R.3
  • 37
    • 0014429801 scopus 로고
    • Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics
    • Davis J, Davis BD: Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. J. Biol. Chem. 243, 3312-3316 (1968).
    • (1968) J. Biol. Chem. , vol.243 , pp. 3312-3316
    • Davis, J.1    Davis, B.D.2
  • 38
    • 0025733603 scopus 로고
    • Ribosomal RNA and translation
    • Noller HF: Ribosomal RNA and translation. Annu. Rev. Biochem. 60, 191-227 (1991).
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 191-227
    • Noller, H.F.1
  • 39
    • 0027226069 scopus 로고
    • Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness
    • Prezant TR, Agapian JV, Bohlman MC et al.: Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness. Nat. Genet. 4, 289-294 (1993).
    • (1993) Nat. Genet. , vol.4 , pp. 289-294
    • Prezant, T.R.1    Agapian, J.V.2    Bohlman, M.C.3
  • 40
    • 0023226742 scopus 로고
    • Crosslinking of streptomycin to the 16S ribosomal RNA of Escherichia coli
    • Gravel M, Melancon P, Brakier-Gingras L: Crosslinking of streptomycin to the 16S ribosomal RNA of Escherichia coli. Biochemistry 26, 6227-6232 (1987).
    • (1987) Biochemistry , vol.26 , pp. 6227-6232
    • Gravel, M.1    Melancon, P.2    Brakier-Gingras, L.3
  • 41
    • 0019908820 scopus 로고
    • Identification of the paromomycin-resistance mutation in the 15S rRNA gene of yeast mitochondria
    • Li M, Tzagaloff A, Underbrink-Lyon K, Martin NC: Identification of the paromomycin-resistance mutation in the 15S rRNA gene of yeast mitochondria. J. Biol. Chem. 257, 5921-5928 (1982).
    • (1982) J. Biol. Chem. , vol.257 , pp. 5921-5928
    • Li, M.1    Tzagaloff, A.2    Underbrink-Lyon, K.3    Martin, N.C.4
  • 42
    • 0021892944 scopus 로고
    • The nucleotide sequence of the 17S ribosomal RNA gene of Tetrahymena thermophila and the identification of point mutations resulting in resistance to the antibiotics paromomycin and hygromycin
    • Spangler EA, Blackburn EH: The nucleotide sequence of the 17S ribosomal RNA gene of Tetrahymena thermophila and the identification of point mutations resulting in resistance to the antibiotics paromomycin and hygromycin. J. Biol. Chem. 260, 6334-6340 (1985).
    • (1985) J. Biol. Chem. , vol.260 , pp. 6334-6340
    • Spangler, E.A.1    Blackburn, E.H.2
  • 43
    • 0027218979 scopus 로고
    • A molecular basis for human hypersensitivity to aminoglycoside antibiotics
    • Hutchin T, Haworth I, Higashi K et al.: A molecular basis for human hypersensitivity to aminoglycoside antibiotics. Nucleic Acids Res. 21, 4174-4179 (1993).
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4174-4179
    • Hutchin, T.1    Haworth, I.2    Higashi, K.3
  • 44
    • 0029916599 scopus 로고    scopus 로고
    • Non-syndromic deafness associated with a mutation and a polymorphism in the mitochondrial 12S ribosomal RNA gene in a large Zairean pedigree
    • Matthijs G, Claes S, Longo-Mbenza B, Cassiman J-J: Non-syndromic deafness associated with a mutation and a polymorphism in the mitochondrial 12S ribosomal RNA gene in a large Zairean pedigree. Eur. J. Hum. Genet. 4, 46-51 (1996).
    • (1996) Eur. J. Hum. Genet. , vol.4 , pp. 46-51
    • Matthijs, G.1    Claes, S.2    Longo-Mbenza, B.3    Cassiman, J.-J.4
  • 45
    • 0031055387 scopus 로고    scopus 로고
    • Mutation in the mitochondrial 12S rRNA gene in two families from Mongolia with matrilineal aminoglycoside ototoxicity
    • Pandya A, Xia X, Radnaabazar J et al.: Mutation in the mitochondrial 12S rRNA gene in two families from Mongolia with matrilineal aminoglycoside ototoxicity. J. Med. Genet. 34, 169-172 (1997).
    • (1997) J. Med. Genet. , vol.34 , pp. 169-172
    • Pandya, A.1    Xia, X.2    Radnaabazar, J.3
  • 46
    • 0343852695 scopus 로고    scopus 로고
    • Two large Spanish pedigrees with non-syndromic sensorineural deafness and the mtDNA mutation at nt 1555 in the 12SrRNA gene: Evidence of heteroplasmy
    • El-Schahawi M, deMunain L, Sarrazin AM et al.: Two large Spanish pedigrees with non-syndromic sensorineural deafness and the mtDNA mutation at nt 1555 in the 12SrRNA gene: evidence of heteroplasmy. Neurology 48, 453-456 (1997).
    • (1997) Neurology , vol.48 , pp. 453-456
    • El-Schahawi, M.1    deMunain, L.2    Sarrazin, A.M.3
  • 47
    • 17344365276 scopus 로고    scopus 로고
    • Familial progressive sensorineural deafness is mainly due to the mtDNA A1555G mutation and is enhanced by treatment with aminoglycosides
    • Estivill X, Govea N, Barcelo A et al.: Familial progressive sensorineural deafness is mainly due to the mtDNA A1555G mutation and is enhanced by treatment with aminoglycosides. Am. J. Hum. Genet. 62, 27-35 (1998).
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 27-35
    • Estivill, X.1    Govea, N.2    Barcelo, A.3
  • 48
    • 0032942192 scopus 로고    scopus 로고
    • Aminoglycoside induced deafness in an Israeli Jewish family with a mitochondrial ribosomal RNA gene mutation
    • Shohat M, Fischel-Ghodsian N, Legum C, Halpern GJ: Aminoglycoside induced deafness in an Israeli Jewish family with a mitochondrial ribosomal RNA gene mutation. Am. J. Otolaryngol. 20, 64-67 (1999).
    • (1999) Am. J. Otolaryngol. , vol.20 , pp. 64-67
    • Shohat, M.1    Fischel-Ghodsian, N.2    Legum, C.3    Halpern, G.J.4
  • 49
    • 0344167734 scopus 로고    scopus 로고
    • Cosegregation of C-insertion at position 961 with A1555G mutation of mitochondrial 12S rRNA gene in a large Chinese family with maternally inherited hearing loss
    • Li R, Xing G, Yan M et al: Cosegregation of C-insertion at position 961 with A1555G mutation of mitochondrial 12S rRNA gene in a large Chinese family with maternally inherited hearing loss. Am. J. Med. Genet. 124A, 113-117 (2004).
    • (2004) Am. J. Med. Genet. , vol.124 A , pp. 113-117
    • Li, R.1    Xing, G.2    Yan, M.3
  • 50
    • 0027515721 scopus 로고
    • Mitochondrial ribosomal RNA mutation associated with aminoglycoside ototoxicity
    • Fischel-Ghodsian N, Prezant TR, Bu X, Oztas S: Mitochondrial ribosomal RNA mutation associated with aminoglycoside ototoxicity. Am. J. Otolaryngol. 14, 399-403 (1993).
    • (1993) Am. J. Otolaryngol. , vol.14 , pp. 399-403
    • Fischel-Ghodsian, N.1    Prezant, T.R.2    Bu, X.3    Oztas, S.4
  • 51
    • 0030974247 scopus 로고    scopus 로고
    • Mitochondrial gene mutations: A common predisposing factor in aminoglycoside ototoxicity
    • Fischel-Ghodsian N, Prezant TR, Chaltraw W et al.: Mitochondrial gene mutations: a common predisposing factor in aminoglycoside ototoxicity. Am. J. Otolaryngol. 18, 173-178 (1997 ).
    • (1997) Am. J. Otolaryngol. , vol.18 , pp. 173-178
    • Fischel-Ghodsian, N.1    Prezant, T.R.2    Chaltraw, W.3
  • 52
    • 0042828920 scopus 로고    scopus 로고
    • Heteroplasmy for the 1555A > G mutation in the mitochondrial 12S rRNA gene in six Spanish families with non-syndromic hearing loss: Implications for genetic diagnosis and counseling
    • del Castillo FJ, Rodriguez-Ballesteros M, Martin Y et al. Heteroplasmy for the 1555A > G mutation in the mitochondrial 12S rRNA gene in six Spanish families with non-syndromic hearing loss: implications for genetic diagnosis and counseling. J. Med. Genet. 40, 632-636 (2003).
    • (2003) J. Med. Genet. , vol.40 , pp. 632-636
    • del Castillo, F.J.1    Rodriguez-Ballesteros, M.2    Martin, Y.3
  • 54
    • 0031958231 scopus 로고    scopus 로고
    • Mitochondrial genetics and hearing loss - The missing link between genotype and phenotype
    • Fischel-Ghodsian N: Mitochondrial genetics and hearing loss - the missing link between genotype and phenotype. Proc. Soc. Exp. Biol. Med. 218, 1-6 (1998).
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.218 , pp. 1-6
    • Fischel-Ghodsian, N.1
  • 55
    • 0031917201 scopus 로고    scopus 로고
    • Mitochondrial mutations and hearing loss - Paradigm for mitochondrial genetics
    • Fischel-Ghodsian N: Mitochondrial mutations and hearing loss - paradigm for mitochondrial genetics. Am. J. Hum. Genet. 62, 15-19 (1998).
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 15-19
    • Fischel-Ghodsian, N.1
  • 56
    • 0033911449 scopus 로고    scopus 로고
    • Candidate locus for a nuclear modifier gene for maternally inherited deafness
    • Bykhovskaya Y, Estivill X, Taylor K et al.: Candidate locus for a nuclear modifier gene for maternally inherited deafness. Am. J. Hum. Genet. 66, 1905-1910 (2000).
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 1905-1910
    • Bykhovskaya, Y.1    Estivill, X.2    Taylor, K.3
  • 57
    • 18544371057 scopus 로고    scopus 로고
    • Linkage and linkage disequilibrium mapping of a nuclear modifier gene for maternally inherited deafness
    • Bykhovskaya Y, Yang H, Taylor K et al.: Linkage and linkage disequilibrium mapping of a nuclear modifier gene for maternally inherited deafness. Genet. Med. 3, 177-180 (2001).
    • (2001) Genet. Med. , vol.3 , pp. 177-180
    • Bykhovskaya, Y.1    Yang, H.2    Taylor, K.3
  • 58
    • 1942425120 scopus 로고    scopus 로고
    • Human mitochondrial transcription factor B1 as a modifier gene for hearing loss associated with the mitochondrial A1555G mutation
    • Bykhovskaya Y, Mengesha E, Wang D et al.: Human mitochondrial transcription factor B1 as a modifier gene for hearing loss associated with the mitochondrial A1555G mutation. Mol. Genet. Metab. 82, 27-32 (2004).
    • (2004) Mol. Genet. Metab. , vol.82 , pp. 27-32
    • Bykhovskaya, Y.1    Mengesha, E.2    Wang, D.3
  • 59
    • 8144221376 scopus 로고    scopus 로고
    • Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3
    • Bykhovskaya Y, Mengesha E, Wang D et al.: Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3. Mol. Genet. Metab. 83, 199-206 (2004).
    • (2004) Mol. Genet. Metab. , vol.83 , pp. 199-206
    • Bykhovskaya, Y.1    Mengesha, E.2    Wang, D.3
  • 60
    • 0037178851 scopus 로고    scopus 로고
    • Isolation and chanracterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12S rRNA A1555G mutation
    • Li X, Li R, Lin X, Guan MX: Isolation and chanracterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12S rRNA A1555G mutation. J. Biol. Chem. 277, 27256-27264 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 27256-27264
    • Li, X.1    Li, R.2    Lin, X.3    Guan, M.X.4
  • 61
    • 0036837683 scopus 로고    scopus 로고
    • A human mitochondrial GTP binding protein related to tRNA modification may modulate the phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation
    • Li X, Guan MX: A human mitochondrial GTP binding protein related to tRNA modification may modulate the phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. Mol. Cell. Biol. 22, 7701-7711 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7701-7711
    • Li, X.1    Guan, M.X.2
  • 62
    • 0029003553 scopus 로고
    • Susceptibility mutations in the mitochondrial small ribosomal RNA gene in aminoglycoside induced deafness
    • Bacino CM, Prezant TR, Bu X, Fournier P, Fischel-Ghodsian N: Susceptibility mutations in the mitochondrial small ribosomal RNA gene in aminoglycoside induced deafness. Pharmacogenetics 5, 165-172 (1995).
    • (1995) Pharmacogenetics , vol.5 , pp. 165-172
    • Bacino, C.M.1    Prezant, T.R.2    Bu, X.3    Fournier, P.4    Fischel-Ghodsian, N.5
  • 63
    • 13044279515 scopus 로고    scopus 로고
    • Inherited susceptibility to aminoglycoside ototoxicity: Genetic heterogeneity and clinical implications
    • Casano RAMS, Johnson DF, Hamon M et al.: Inherited susceptibility to aminoglycoside ototoxicity: genetic heterogeneity and clinical implications. Am. J. Otolaryngol. 20, 151-156 (1999).
    • (1999) Am. J. Otolaryngol. , vol.20 , pp. 151-156
    • Casano, R.A.M.S.1    Johnson, D.F.2    Hamon, M.3
  • 65
    • 85028790817 scopus 로고    scopus 로고
    • Relative frequencies of the mitochondrial A1555G and 961 delT mutations in the 12SrRNA gene in a large sample of deaf probands from the United States
    • (Abstract)
    • Arnos K, Xia XJ, Norris G et al.: Relative frequencies of the mitochondrial A1555G and 961 delT mutations in the 12SrRNA gene in a large sample of deaf probands from the United States. Am. J. Hum. Genet. 73, 2196 (2003) (Abstract).
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 2196
    • Arnos, K.1    Xia, X.J.2    Norris, G.3
  • 66
    • 0347003512 scopus 로고    scopus 로고
    • Maternally inherited aminoglycoside-induced and non-syndromic deafness associated with the novel C1494T mutation in the mitochondrial 12S rRNA gene in a large Chinese family
    • Zhao H, li R, Wang Q et al.: Maternally inherited aminoglycoside-induced and non-syndromic deafness associated with the novel C1494T mutation in the mitochondrial 12S rRNA gene in a large Chinese family. Am. J. Hum. Genet. 74, 139-152 (2004).
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 139-152
    • Zhao, H.1    Li, R.2    Wang, Q.3
  • 67
    • 0033768121 scopus 로고    scopus 로고
    • A novel mitochondrial 12SrRNA point mutation in parkinsonism, deafness and neuropathy
    • Thyagarajan D, Bressman S, Bruno C et al.: A novel mitochondrial 12SrRNA point mutation in parkinsonism, deafness and neuropathy. Ann. Neurol. 48, 730-736 (2000).
    • (2000) Ann. Neurol. , vol.48 , pp. 730-736
    • Thyagarajan, D.1    Bressman, S.2    Bruno, C.3
  • 69
    • 8844236333 scopus 로고    scopus 로고
    • Clinical evaluation and sequence analysis of the complete mitochondrial genome of three Chinese patients with hearing impairment associated with the 12S rRNA T1095C mutation
    • Zhao L, Young W-Y, Li R, Wang Q, Qian Y, Guan M-X: Clinical evaluation and sequence analysis of the complete mitochondrial genome of three Chinese patients with hearing impairment associated with the 12S rRNA T1095C mutation. Biochem. Biophys. Red. Com. 325, 1503-1508 (2004).
    • (2004) Biochem. Biophys. Red. Com. , vol.325 , pp. 1503-1508
    • Zhao, L.1    Young, W.-Y.2    Li, R.3    Wang, Q.4    Qian, Y.5    Guan, M.-X.6
  • 70
    • 2342572275 scopus 로고    scopus 로고
    • A novel mitochondrial mutation, 1556C→T, in a Japanese patient with streptomycin-induced tinnitus
    • Tanimoto H, Nishio H, Matsuo M, Nibu K-I: A novel mitochondrial mutation, 1556C→T, in a Japanese patient with streptomycin-induced tinnitus. Acta Otolaryngol. 124, 258-261 (2004).
    • (2004) Acta Otolaryngol. , vol.124 , pp. 258-261
    • Tanimoto, H.1    Nishio, H.2    Matsuo, M.3    Nibu, K.-I.4
  • 71
    • 0027404833 scopus 로고
    • Ultrastructural evidence for hair cell regeneration in the mammalian inner ear
    • Forge A, Li L, Corwin JT. Nevill G: Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science 259, 1616-1619 (1993).
    • (1993) Science , vol.259 , pp. 1616-1619
    • Forge, A.1    Li, L.2    Corwin, J.T.3    Nevill, G.4
  • 72
    • 0027531639 scopus 로고
    • Regenerative proliferation in inner ear sensory epithelia from adult guinea-pigs and humans
    • Warchol ME, Lambert PR, Goldstein BJ, Forge A, Corwin JT. Regenerative proliferation in inner ear sensory epithelia from adult guinea-pigs and humans. Science 259, 1619-1622 (1993).
    • (1993) Science , vol.259 , pp. 1619-1622
    • Warchol, M.E.1    Lambert, P.R.2    Goldstein, B.J.3    Forge, A.4    Corwin, J.T.5
  • 74
    • 0030460674 scopus 로고    scopus 로고
    • Identification of an overexpressed yeast gene which prevents aminoglycoside toxicity
    • Prezant TR, Chaltraw W. Fischel-Ghodsian N: Identification of an overexpressed yeast gene which prevents aminoglycoside toxicity. Microbiol. 142, 3407-3414 (1996).
    • (1996) Microbiol. , vol.142 , pp. 3407-3414
    • Prezant, T.R.1    Chaltraw, W.2    Fischel-Ghodsian, N.3
  • 76
    • 0015450966 scopus 로고
    • The genetics of bacterial ribosomes
    • Davies J, Nomura M: The genetics of bacterial ribosomes. Annu. Rev. Genet. 6, 203-234 (1972).
    • (1972) Annu. Rev. Genet. , vol.6 , pp. 203-234
    • Davies, J.1    Nomura, M.2
  • 77
    • 0016725415 scopus 로고
    • Analysis of ribosomal proteins in streptomycin resistant and dependent mutants isolated from streptomycin independent Escherichia coli strains
    • Wittmann HG, Apirion D: Analysis of ribosomal proteins in streptomycin resistant and dependent mutants isolated from streptomycin independent Escherichia coli strains. Mol. Gen. Genet. 141, 331-341 (1975).
    • (1975) Mol. Gen. Genet. , vol.141 , pp. 331-341
    • Wittmann, H.G.1    Apirion, D.2
  • 78
    • 0016797562 scopus 로고
    • Protein chemical studies on ribosomal proteins S4 and S12 from ram (ribosomal ambiguity) mutants of Escherichia coli
    • Van Acken U: Protein chemical studies on ribosomal proteins S4 and S12 from ram (ribosomal ambiguity) mutants of Escherichia coli. Mol. Gen. Genet. 140, 61-68 (1975).
    • (1975) Mol. Gen. Genet. , vol.140 , pp. 61-68
    • Van Acken, U.1
  • 79
    • 0026592739 scopus 로고
    • Nam9 nuclear suppressor of mitochondrial ochre mutations in Saccharomyces cerevisiae codes for a protein homologous to S4 ribosomal proteins from chloroplasts, bacteria, and eukaryotes
    • Boguta M, Dmochowska A, Borsuk P et al.: Nam9 nuclear suppressor of mitochondrial ochre mutations in Saccharomyces cerevisiae codes for a protein homologous to S4 ribosomal proteins from chloroplasts, bacteria, and eukaryotes. Mol. Cell Biol. 12(1 , 402-412 (1992).
    • (1992) Mol. Cell Biol. , vol.12 , Issue.1 , pp. 402-412
    • Boguta, M.1    Dmochowska, A.2    Borsuk, P.3
  • 80
    • 0023663056 scopus 로고
    • The tko locus, site of a behavioural mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12
    • Royden, CS, Pirrotta V, Jan LY. The tko locus, site of a behavioural mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12. Cell 51, 165-173 (1987).
    • (1987) Cell , vol.51 , pp. 165-173
    • Royden, C.S.1    Pirrotta, V.2    Jan, L.Y.3
  • 81
    • 0032531250 scopus 로고    scopus 로고
    • Cloning and characterization of the human mitochondrial ribosomal S12 gene
    • Johnson DF, Hamon M, Fischel-Ghodsian N: Cloning and characterization of the human mitochondrial ribosomal S12 gene. Genomics 52, 363-368 (1998).
    • (1998) Genomics , vol.52 , pp. 363-368
    • Johnson, D.F.1    Hamon, M.2    Fischel-Ghodsian, N.3
  • 82
    • 0030827973 scopus 로고    scopus 로고
    • Specific binding of aminoglycosides to a human rRNA construct based on a DNA polymorphism which causes aminoglycoside-induced deafness
    • Hamasaki K, Rando RR: Specific binding of aminoglycosides to a human rRNA construct based on a DNA polymorphism which causes aminoglycoside-induced deafness. Biochemistry 36, 12323-12328 (1997).
    • (1997) Biochemistry , vol.36 , pp. 12323-12328
    • Hamasaki, K.1    Rando, R.R.2
  • 83
    • 0030016359 scopus 로고    scopus 로고
    • Biochemical evidence for nuclear gene involvement in phenotype of non-syndromic deafness associated with mitochondrial 12S rRNA mutation
    • Guan MX, Fischel-Ghodsian N, Attardi G: Biochemical evidence for nuclear gene involvement in phenotype of non-syndromic deafness associated with mitochondrial 12S rRNA mutation. Hum. Mol. Genet. 5, 963-972 (1996).
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 963-972
    • Guan, M.X.1    Fischel-Ghodsian, N.2    Attardi, G.3
  • 84
    • 0033858002 scopus 로고    scopus 로고
    • A biochemical basis for the inherited susceptibility to aminoglycoside ototoxicity
    • Guan MX, Fischel-Ghodsian N, Attardi G: A biochemical basis for the inherited susceptibility to aminoglycoside ototoxicity Hum. Mol. Genet. 9, 1787-1793 (2000).
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1787-1793
    • Guan, M.X.1    Fischel-Ghodsian, N.2    Attardi, G.3
  • 86
    • 0029832209 scopus 로고    scopus 로고
    • Audio-vestibular findings in patients with deafness caused by a mitochondrial susceptibility mutation and precipitated by an inherited nuclear mutation or aminoglycosides
    • Braverman I, Jaber L, Levi H et al.: Audio-vestibular findings in patients with deafness caused by a mitochondrial susceptibility mutation and precipitated by an inherited nuclear mutation or aminoglycosides. Arch. Otolaryngol. Head Neck Surg. 122, 1001-1004 (1996).
    • (1996) Arch. Otolaryngol. Head Neck Surg. , vol.122 , pp. 1001-1004
    • Braverman, I.1    Jaber, L.2    Levi, H.3
  • 87
    • 0030778977 scopus 로고    scopus 로고
    • Protection from gentamicin ototoxicity by iron chelators in guinea-pig in vivo
    • Song BB, Anderson DJ, Schacht J: Protection from gentamicin ototoxicity by iron chelators in guinea-pig in vivo. J. Pharmacol. Exp. Ther. 282, 369-377 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 369-377
    • Song, B.B.1    Anderson, D.J.2    Schacht, J.3
  • 88
    • 0029850284 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss
    • Basile S, Huang J-M, Xie C, Webster D, Berlin C, Skolnick P: N-Methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. Nat. Med. 2, 1338-1343 (1996).
    • (1996) Nat. Med. , vol.2 , pp. 1338-1343
    • Basile, S.1    Huang, J.-M.2    Xie, C.3    Webster, D.4    Berlin, C.5    Skolnick, P.6
  • 89
    • 19144362852 scopus 로고    scopus 로고
    • Protection of auditory neurons from aminoglycoside toxicity by neurotrophin-3
    • Ernfors P, Duan ML, ElShamy WM, Canlon B: Protection of auditory neurons from aminoglycoside toxicity by neurotrophin-3. Nat. Med. 2, 463-467 (1996).
    • (1996) Nat. Med. , vol.2 , pp. 463-467
    • Ernfors, P.1    Duan, M.L.2    ElShamy, W.M.3    Canlon, B.4


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