Design, synthesis and evaluation of novel hydroxyamides as orally available anticonvulsants

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 5, 2004, Pages 979-993

  Schenck, Hilary A ^a   Lenkowski, Paul W ^a   Choudhury Mukherjee, Indrani ^a   Ko, Seong Hoon ^b   Stables, James P ^c   Patel, Manoj K ^b   Brown, Milton L ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Alcohols; Amides; Calcium channel; Ion channel

Indexed keywords

3,3,3 TRIFLUORO 2 HYDROXY 2 PHENYLPROPIONAMIDE; AMIDE; ANTICONVULSIVE AGENT; ATROLACTAMIDE; CALCIUM ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PATCH CLAMP; RAT; STRUCTURE ACTIVITY RELATION;

TRIFLUORO;

EID: 1342323482     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.12.011     Document Type: Article

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