Topical treatments in equine wound management

Veterinary Clinics of North America - Equine Practice

Volumn 21, Issue 1, 2005, Pages 77-89

  Dart, Andrew J ^a,b   Dowling, Brad A ^a   Smith, Christine L ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Univ Centre Veterinary Centre PMB 4   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACEMANNAN; ALOE VERA EXTRACT; CARRASORB; CARRAVET; COPPER COMPLEX; CORTICOSTEROID; EQUIGEN; GROWTH FACTOR; GROWTH HORMONE; INTRACELL; KETANSERIN; MALTODEXTRIN; PHENYLALANINE; PHENYTOIN; RECOMBINANT GROWTH HORMONE; SOLCOSERYL; SUGAR; TETRAPEPTIDE; TRANSFORMING GROWTH FACTOR BETA; TRIPEPTIDE DERIVATIVE;

ALOE VERA; EPITHELIZATION; GRANULATION TISSUE; HORSE; INFLAMMATION; LEUKOCYTE; NONHUMAN; OXYGEN TENSION; REVIEW; SCAR FORMATION; SUPERNATANT; TEMPERATURE; THROMBOCYTE RICH PLASMA; VASCULARIZATION; WOUND CONTRACTION; WOUND HEALING;

ADMINISTRATION, TOPICAL; ANIMALS; CYTOKINES; GROWTH SUBSTANCES; HORSE DISEASES; HORSES; WOUND HEALING; WOUND INFECTION; WOUNDS AND INJURIES;

ALOE; ALOE VERA; EQUIDAE; EQUUS CABALLUS;

EID: 13244279675     PISSN: 07490739     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cveq.2004.11.003     Document Type: Review

References (75)

1. C.L. Theoret Growth factors in pathologic wound repair in horses Compend Contin Educ Pract Vet 23 2001 479 482
2. D.C. Knottenbelt Equine wound management: are there significant differences in healing at different sites on the body? Vet Dermatol 8 1997 273 290
3. J.M. Wilmink, P.R. Van Weeren, and P.W. Stolk Differences in second intention wound healing between horses and ponies: histological aspects Equine Vet J 31 1999 61 67
4. J.M. Wilmink, J.N. Veenman, and R. van den Boom Differences in polymorphonucleocyte function and local inflammatory response between horses and ponies Equine Vet J 35 2003 561 569
5. J.M. Wilmink, P.W. Stolk, and P.R. Van Weeren Differences in second intention wound healing between horses and ponies: macroscopic aspects Equine Vet J 31 1999 53 60
6. C. Bacon Miller, D.A. Wilson, and K.G. Keegan Growth characteristic of fibroblasts isolated from the trunk and distal aspect of the limb of horses and ponies Vet Surg 29 2000 1 7
7. R. Van den Boom, J.M. Wilmink, and S. Okane Transforming growth factor-β levels during second-intention healing are related to the different course of wound contraction in horses and ponies Wound Repair Regen 10 2002 188 194
8. C.L. Theoret, S.M. Barber, and T.N. Moyana Expression of transforming growth factor β1, β3 and basic fibroblast growth factor in full-thickness skin wounds of equine limbs and thorax Vet Surg 30 2001 269 277
9. C.L. Theoret, S.M. Barber, and T.N. Moyana Preliminary observations on the expression of transforming growth factors β1 and β3 in equine full thickness skin wounds healing normally or with exuberant granulation tissue Vet Surg 31 2002 266 273
10. M. Shah, D.M. Foreman, and M.W.J. Ferguson Neutralization of TGF β1 and TGF β2 to cutaneous rat wounds reduces scarring J Cell Sci 108 1995 985 1002
11. K.A. Jacobs, D.H. Leach, and P.B. Fretz Comparative aspects of the healing of excisional wounds of the leg and body of horses Vet Surg 12 1984 83 90
12. S.F. Swaim, S.H. Hinkle, and D.M. Bradley Wound contraction: basic and clinical factors Compend Contin Educ Pract Vet 23 2001 20 34
13. J.M. Wilmink, H. Nederbrag, and P.R. van Weeren Differences in wound contraction between horses and ponies: the in vitro contraction capacity of fibroblasts Equine Vet J 33 2001 499 505
14. A.J. Schwartz, D.A. Wilson, and K.G. Keegan Factors regulating collagen synthesis and degradation during second-intention healing of wounds in the thoracic region and the distal aspect of the forelimb in horses Am J Vet Res 63 2002 1564 1570
15. C.A. Carter, D.G. Jolly, and C.E. Worden Platelet rich plasma gel promotes differentiation and regeneration during equine wound healing Exp Mol Pathol 74 2003 244 255
16. G.A. Ksander, G.H. Chu, and H. McMuillin Transforming growth factors-β1 and β2 enhance connective tissue formation in animal models of dermal wound healing by secondary intent Ann NY Acad Sci 593 1990 135 137
17. M.C. Robson, T.A. Mustoe, and T.K. Hunt The future of recombinant growth factors in wound healing Am J Surg 176 1998 80 82
18. G.S. Ashcroft, X. Yang, and A.B. Glick Mice lacking Smad 3 show accelerated wound healing and an impaired local inflammatory response Nat Cell Biol 1 1999 260 266
19. C.M. Steel, I.D. Robertson, and J. Thomas Effect of topical rh-TGF-β-1 on second intention wound healing in horses Aust Vet J 77 1999 734 737
20. B.M. Choi, H.J. Kwak, and C.D. Jun Control of scarring in adult wounds using antisense transforming growth factor β1 oligodeoxynucleotides Immunol Cell Biol 74 1996 144 150
21. I. De Martin, and C.L. Theoret Spatial and temporal expression of types I and II receptors for transforming growth factor β in normal equine and dermal wounds Vet Surg 33 2004 70 76
22. P. Harrison, and E.M. Cramer Platelet α-granules Blood Rev 7 1993 52 62
23. A.R. Sanchez, P.J. Sheridan, and L.I. Kupp Is platelet-rich plasma the perfect enhancement factor? A current review Int J Oral Maxillofac Implants 18 2003 93 103
24. D.R. Knighton, K. Ciresi, and V.D. Fiegel Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula Surg Gynecol Obstet 170 1990 56 60
25. H. Renz, J.H. Gong, and A. Schmidt Release of tumour necrosis factor-α from macrophages: enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleopeptides J Immunol 141 1988 2388 2393
26. M.J. Concannon, B.B. Barrett, and E.H. Adelstein The inhibition of fibroblast proliferation by a novel monokine: an in vitro and in vivo study J Burn Care Rehabil 14 1993 141 147
27. D.A. Wilson, E.H. Adelstein, and K.G. Keegan In vitro and in vivo effects of activated macrophage supernatant on distal limb wounds in ponies Am J Vet Res 57 1996 1220 1224
28. A.J. Dart, L. Creis, and L.B. Jeffcott The effect of equine recombinant growth hormone on second intention wound healing in horses Vet Surg 31 2002 314 319
29. M. Seyer-Hansen, T.T. Andreassen, and H. Oxlund Strength of colonic anastomoses and skin incisional wounds in old rats - influence by diabetes and growth hormone Growth Horm IGF Res 9 1999 254 261
30. I.S. Thorey, B. Hinz, and A. Hoeflich Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis and myofibroblast differentiation J Biol Chem 279 2004 2667 2684
31. J.M. Wilmink, P.W.Th Stolk, and R. van Weeren The effectiveness of the haemodialysate Solcoseryl for second intention wound healing in horses and ponies J Vet Med 47 2000 311 318
32. T. Schreier, E. Degen, and W. Baschong Fibroblast migration and proliferation during in vitro wound healing Res Exp Med 193 1993 195 205
33. P. Spessato, P. Dri, and W. Baschong Effect of a protein-free dialysate from calf blood on human monocyte differentiation in vitro Arzneimittelforschung 43 1993 747 751
34. W. Jochle, and D. Hamm Effects of topical treatment with Solcoseryl and its fraction 3 on wound healing after burns and surgical lesions in horses S.R. May G. Dogo Care of the burn wound 1983 Karger Basel 83 89
35. H.G. Liebich, W. Hamm, and W. Jochle Histological evaluation of wound healing in horses treated with the protein-free haemodialysate Solcoseryl and its hexosylceramide fraction J Vet Med 35 1988 84 95
36. J. Marichy, and J. Eyraud The wound healing effect of Solcoseryl ointment in the treatment of children with burns Acta Ther 10 1984 107 117
37. C.M. Lawrence, J.N.S. Matthews, and N.H. Cox The effect of ketanserin on healing of fresh surgical wounds Br J Dermatol 132 1995 580 586
38. R.P. Rooman, and H. Janssen Ketanserin promotes wound healing: clinical and preclinical results Prog Clin Biol Res 365 1991 115 128
39. P. Roelens Double-blind placebo-controlled study with topical 2% ketanserin ointment in the treatment of ulcers Dermatologica 178 1989 98 102
40. M. Engelen, B. Besche, and M.P. Lefay Effects of ketanserin on hypergranulation tissue formation, infection, and healing of equine lower limb wounds Can Vet J 45 2004 144 149
41. S.F. Swaim, K.P. Riddell, and J.A. McGuire Effects of topical medication on the healing of open pad wounds in dogs J Am Anim Hosp Assoc 28 1992 1 4
42. S.F. Swaim Advances in wound healing in small animal practice: current status and lines of development Vet Dermatol 8 1997 249 257
43. S.F. Swaim, D.M. Bradley, and J.S. Spano Evaluation of multipeptide-copper complex medications on open wound healing in dogs J Am Anim Hosp Assoc 29 1993 519 525
44. Swaim SF. Emergency wound management. In: Proceedings of the Fifth International Veterinary Emergency Critical Care Symposium. 1996. p. 638-42.
45. S.F. Swaim, and R.L. Gillette An update on wound medications and dressings Compend Contin Educ Pract Vet 20 1998 1133 1144
46. Silvetti AN. The antimicrobial effect of maltodextrin NF in the healing of chronic wounds and ulcers including pressure ulcers. In: Proceedings of the Symposium of Advances in Wound Care Medical and Research Forum into Wound Repair. 1995. p. 70.
47. S. Thomas, and P. Hay Fluid handling properties of hydrogel dressings Ostomy Wound Manage 41 1995 54 59
48. J.M. Liptak An overview of topical management of wounds Aust Vet J 75 1997 408 413
49. J.T. Blackford, L.W. Blackford, and H.S. Adair The use of antimicrobial glucocorticosteroid ointment on granulating lower leg wounds in horses Proc Am Assoc Equine Pract 37 1991 71 77
50. R.B. Bigbie, J. Schumacher, and S.F. Swaim Effects of amnion and live yeast cell derivative on second intention wound healing in horses Am J Vet Res 52 1991 1376 1382
51. S.F. Swaim, and R.A. Hendersen Small animal wound management 2nd edition 1997 Williams & Wilkins Baltimore 53 85
52. W.T. Lawrence Clinical management of nonhealing wounds I.K. Cohen R.F. Diegelmann W.J. Linblad Wound healing: biochemical and clinical aspects 1992 WB Saunders Philadelphia 541 561
53. S.M. Barber Second intention wound healing in the horse: the effect of bandages and topical corticosteroids Proc Am Assoc Equine Pract 35 1989 107 116
54. P. Atherton Aloe vera revisited Br J Phytotherapy 4 1998 176 183
55. J.P. Heggars, A. Kucukelebi, and D. Listengarten Beneficial effect of aloe on wound healing in an excisional wound model J Altern Complement Med 2 1996 271 277
56. J. Gallagher, and M. Gray Is aloe vera effective for healing chronic wounds J Wound Ostomy Contin Nurs 30 2002 68 71
57. M.J. Muller, M.A. Hollyoak, and Z. Maoveni Retardation of wound healing by silver sulfadiazine is reversed by aloe vera and nystatin Burns 29 2003 834 836
58. R.A. Knutson, L.A. Merbitz, and M.A. Creekmore Use of sugar and povidone-iodine to enhance wound healing: five years experience South Med J 74 1981 1329 1335
59. P.C. Molan, and R.A. Cooper Honey and sugar as a dressing for wounds and ulcers Trop Doct 30 2000 249 251
60. O.A. Moore, L.A. Smith, and F. Campbell Systematic review of honey as a wound dressing BMC Complement Altern Med 1 2001 2 7
61. N. Kamat Use of sugar as a dressing for wounds and ulcers Trop Doct 3 2000 1
62. R.A. Cooper, P.C. Molan, and K.G. Harding Antibacterial activity of honey against strains of Staphylococcus aureus from infected wounds J R Soc Med 92 1999 283 285
63. A.J. Tonks, R.A. Cooper, and K.P. Jones Honey stimulates cytokine production from monocytes Cytokine 21 2003 242 247
64. K. Matthews, and A.G. Binnington Wound management using honey Compend Contin Educ Pract Vet 24 2002 53 60
65. P.C. Molan Potential of honey in the treatment of wounds and burns Am J Clin Dermatol 2 2001 13 19
66. K.L. Allen, P.C. Molan, and G.M. Reid A survey of the antibacterial activity of some of New Zealand honeys J Pharm Pharmacol 43 1991 817 822
67. D.J. Willix, P.C. Molan, and C.G. Harfoot A comparison of the sensitivity of wound infecting species of bacteria to the antibacterial activity of Manuka honey and other honey J Appl Bacteriol 73 1992 388 394
68. M.G. Muthukumarasamy, G. Sivakumar, and G. Manoharan Topical phenytoin in diabetic foot ulcers Diabetes Care 14 1991 909 911
69. G. Talas, R.A. Brown, and D.A. McGrouther Role of phenytoin in wound healing - a wound pharmacology perspective Biochem Pharmacol 57 1999 1085 1094
70. P.M.R. Carneiro, and E.T.M. Nyawawa Topical phenytoin versus eusol in the treatment of non-malignant chronic leg ulcers East Afr Med J 80 2004 124 129
71. A.K. Pendse, A. Sharma, and A. Sodani Topical phenytoin in wound healing Int J Dermatol 32 1996 214 217
72. R.A. Sherman Maggot versus conservative debridement therapy for the treatment of pressure ulcers Wound Repair Regen 10 2002 208 215
73. A.J. Horobin, K.M. Shakesheff, and S. Woodrow Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon interactions between human dermal fibroblasts and extracellular matrix components Br J Dermatol 148 2003 923 931
74. U. Wollina, K. Kerte, and C. Herold Biosurgery in wound healing - the renaissance of maggot therapy J Eur Acad Dermatol Venereol 14 2000 285 291
75. Mumcouglu KY, Miller J, Ioffe-Upensky I, et al. The potential of maggots to secrete cytokines in vitro. In: Proceedings of the Fifth International Conference on Biotherapy, Wurzburg, Germany, 2000. p. 23.