Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation

Journal of Biological Chemistry

Volumn 279, Issue 25, 2004, Pages 26674-26684

  Thorey, Irmgard S ^a,b   Hinz, Boris ^c   Hoeflich, Andreas ^b   Kaesler, Susanne ^a   Bugnon, Philippe ^a   Elmlinger, Martin ^d   Wanke, Rüdiger ^b   Wolf, Eckhard ^b   Werner, Sabine ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

^c EPFL   (Switzerland)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; ENZYME INHIBITION; GRANULATION; TISSUE;

GROWTH HARMONE (GH); MYOFIBROBLAST DIFFERENTIATION; VASCULARIZED GRANULATION TISSUE;

BIOCHEMISTRY;

COLLAGEN; GROWTH HORMONE; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY GROWTH; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; FEMALE; GRANULATION TISSUE; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; WOUND CLOSURE; WOUND CONTRACTION; WOUND HEALING;

ACETIC ACID; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; COLLAGEN; DOWN-REGULATION; FEMALE; FIBROBLASTS; GROWTH HORMONE; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; LIGANDS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; MUSCLES; NEOVASCULARIZATION, PHYSIOLOGIC; RADIOIMMUNOASSAY; SEX FACTORS; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

ANIMALIA; MUS MUSCULUS;

EID: 2942726274     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311467200     Document Type: Article

References (48)

1. Martin, P. (1997) Science 276, 75-81
2. Werner, S., and Grose, R. (2003) Physiol. Rev. 83, 835-870
3. Ashcroft, G. S., Dodsworth, J., van Boxtel, E., Tarnuzzer, R. W., Horan, M. A., Schultz, G. S., and Ferguson, M. W. (1997) Nat. Med. 3, 1209-1215
4. Grose, R., Werner, S., Kessler, D., Tuckermann, J., Huggel, K., Durka, S., Reichardt, H. M., and Werner, S. (2002) EMBO Rep. 3, 575-582
5. Ashcroft, G. S., and Mills, S. J. (2002) J. Clin. Investig. 110, 615-624
6. Cummings, D. E., and Merriam, G. R. (2003) Annu. Rev. Med. 54, 513-533
7. Lal, S. O., Wolf, S. E., and Herndon, D. N. (2000) Growth Horm. IGF Res. 10, Suppl. B, 39-43
8. Steenfos, H. H., and Jansson, J. O. (1992) J. Endocrinol. 132, 293-298
9. Seyer-Hansen, M., Andreassen, T. T., Jorgensen, P. H., and Oxlund, H. (1993) Eur. Surg. Res. 25, 162-168
10. Rasmussen, L. H., Garbarsch, C., Schuppan, D., Moe, D., Horslev-Pedersen, K., Gottrup, F., and Steenfos, H. (1995) Eur. J. Surg. 161, 157-162
11. Ghofrani, A., Holler, D., Schuhmann, D., Saldern, S., and Messmer, B. J. (1999) Plast. Reconstr. Surg. 104, 470-475
12. Seyer-Hansen, M., Andreasen, T. T., and Oxlund, H. (1999) Growth Horm. IGF Res. 9, 254-261
13. Welsh, K. M., Lamit, M., and Morhenn, V. B. (1991) J. Dermatol. Surg. Oncol. 17, 942-945
14. Green, H., Morikawa, M., and Nixon, T. (1985) Differentiation 29, 195-198
15. Eming, S. A., Snow, R. G., Yarmush, M. L., and Morgan, J. R. (1996) J. Investig. Dermatol. 107, 113-120
16. Martin, J. L., and Baxter, R. C. (1999) in Contemporary Endocrinology; The IGF System (Rosenfeld, R., and Roberts, C., eds) pp. 227-254, Humana Press Inc., Totowa, NJ
17. Kuroda, K., Utani, A., Hamasaki, Y., and Shinkai, H. (2001) J. Dermatol. Sci. 26, 156-160
18. Clemmons, D. R. (1999) in Contemporary Endocrinology; The IGF System (Rosenfeld, R., and Roberts C., Jr., eds) pp. 273-279, Humana Press Inc., Totowa, NJ
19. Schneider, M. R., Wolf, E., Hoeflich, A., and Lahm, H. (2002) J. Endocrinol. 172, 423-440
20. Lynch, S. E., Colvin, R. B., and Antoniades, H. N. (1989) J. Clin. Investig. 84, 640-646
21. Jyung, R. W., Mustoe, J. A., Busby, W. H., and Clemmons, D. R. (1994) Surgery 115, 233-239
22. Bitar, M. S. (1997) Horm. Metab. Res. 29, 383-386
23. Jeschke, M. G., Barrow, R. E., Hawkins, H. K., Yang, K., Hayes, R. L., Lichtenbelt, B. J., Perez-Polo, J. R., and Herndon, D. N. (1999) Gene Ther. 6, 1015-1020
24. Dunaiski, V., and Belford, D. A. (2002) Growth Horm. IGF Res. 12, 381-387
25. Wolf, E., and Wanke, R. (1996) in Welfare of Transgenic Animals (Zutphen, L. F. M., and van der Meer, M., eds) pp. 26-47, Springer-Verlag, Heidelberg
26. Wanke, R., Milz, S., Rieger, N., Ogiolda, L., Renner-Muller, I., Brem, G., Hermanns, W., and Wolf, E. (1999) J. Investig. Dermatol. 113, 967-971
27. Hoeflich, A., Nedbal, S., Blum, W. F., Erhard, M., Lahm, H., Brem, G., Kolb, H. J., Wanke, R., and Wolf, E. (2001) Endocrinology 142, 1889-1898
28. Skalli, O., Ropraz, P., Trzeciak, A., Benzonana, G., Gillessen, D., and Gabbiani, G. (1986) J. Cell Biol. 103, 2787-2796
29. Borsi, L., Carnemolla, B., Castellani, P., Rosellini, C., Vecchio, D., Allemanni, G., Chang, S. E., Taylor-Papadimitriou, J., Pande, H., and Zardi, L. (1987) J. Cell Biol. 104, 595-600
30. Hinz, B., Mastrangelo, D., Iselin, C. E., Chaponnier, C., and Gabbiani, G. (2001) Am. J. Pathol. 159, 1009-1020
31. Hinz, B., Celetta, G., Tomasek, J. J., Gabbiani, G., and Chaponnier, C (2001) Mol. Biol. Cell 12,2730-2741
32. Kessler, D., Dethlefsen, S., Haase, I., Plomann, M., Hirche, F., Krieg, T., and Eckes, B. (2001) J. Biol. Chem. 276, 36575-36585
33. Hossenlopp, P., Seurin, D., Segovia Quinson, B., Hardouin, S., and Binoux, M. (1986) Anal. Biochem. 154, 138-143
34. Wolf, E., Kramer, R., Blum, W. F., Foll, J., and Brem, G. (1994) Endocrinology 135, 1877-1886
35. Bang, P., Baxter, R. C., Blum, W. F., Breier, B. H., Clemmons, D. R., Hall, K., Hintz, R. L., Holly, J. M., Rosenfeld, R. G., and Zapf, J. (1994) J. Endocrinol. 143, C1-C2
36. Hoeflich, A., Wu, M., Mohan, S., Föll, J., Wanke, R., Froehlich, T., Arnold, G., Lahm, H., Kolb, H. J., and Wolf, E. (1999) Endocrinology 140, 5488-5496
37. Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., and Brown, R. A. (2002) Nat. Rev. Mol. Cell Biol. 3, 349-363
38. Serini, G., Bochaton-Piallat, M. L., Ropraz, P., Geinoz, A., Borsi, L., Zardi, L., and Gabbiani, G. (1998) J. Cell Biol. 142, 873-881
39. Bell, E., Ivarsson, B., and Merrill, C. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 1274-1278
40. Desmouliere, A., Geinoz, A., Gabbiani, F., and Gabbiani, G. (1993) J. Cell Biol. 122, 103-111
41. Frank, S., Madlener, M., and Werner, S. (1996) J. Biol. Chem. 271, 10188-10193
42. Giannini, S., Mohan, S., Kasuya, J., Galli, G., Rotella, C. M., LeBon, T. R., and Fujita-Yamaguichi, Y. (1994) J. Clin. Endocrinol. Metabol. 79, 1824-1830
43. Zaizen, Z., Ford, E. G., Shimada, H., Kosi, M., Costin, G., and Atkinson, J. B. (1995) Eur. J. Pediatr. Surg. 5, 226-230
44. Gould, J., Aramburo, C., Capdevielle, M., and Scanes, C. G. (1995) Life Sci. 56, 587-594
45. Struman, I., Bentzien, F., Lee, H., Mainfroid, V., D'Angelo, G., Goffin, V., Weiner, R. I., and Martial, J. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1246-12451
46. Ehrlich, H. P., and Rajaratnam, J. B. (1990) Tissue & Cell 22, 407-417
47. Lee, Y. R., Oshita, Y., and Tsuboi, R. (1996) Endocrinology 137, 5378-5383
48. Kanekar, S., Borg, T. K., Terracio, L., and Carver, W. (2000) Cell Adhes. Commun. 7, 513-523