Neurotoxic regimens of methamphetamine induce persistent expression of phospho-c-Jun in somatosensory cortex and substantia nigra

Synapse

Volumn 55, Issue 3, 2005, Pages 137-147

  O'Dell, Steven J ^a   Marshall, John F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Barrel field; Excitotoxicity; Fluoro Jade; Parietal; S1

Indexed keywords

METHAMPHETAMINE; PHOSPHOTRANSFERASE; PROTEIN C JUN;

ACCIDENT PREVENTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; HEMISPHERE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOMATOSENSORY CORTEX; SOMATOSENSORY DISORDER; STAINING; SUBSTANTIA NIGRA; VIBRISSA;

AFFERENT PATHWAYS; ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELL SURVIVAL; DENERVATION; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FLUORESCENT DYES; IMMUNOHISTOCHEMISTRY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; METHAMPHETAMINE; NERVE DEGENERATION; NEUROTOXINS; ORGANIC CHEMICALS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX; SUBSTANTIA NIGRA; TIME FACTORS; VIBRISSAE;

EID: 13244277690     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.20098     Document Type: Article

References (65)

1. Behrens A, Sibilia M, Wagner EF. 1999. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat Genet 21:326-329.
2. Bowyer JF, Tank AW, Newport GD, Slikker W Jr, Ali SF, Holson RR. 1992. The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum. J Pharmacol Exp Ther 260:817-824.
3. Bowyer JF, Davies DL, Schmued L, Broening HW, Newport GD, Slikker W, Jr., Holson RR. 1994. Further studies of the role of hyperthermia in methamphetamine neurotoxicity. J Pharmacol Exp Ther 268:1571-1580.
4. Bowyer JF, Peterson SL, Rountree RL, Tor-Agbidye J, Wang GJ. 1998. Neuronal degeneration in rat forebrain resulting from D-amphetamine-induced convulsions is dependent on seizure severity and age. Brain Res 809:77-90.
5. Brecht S, Martin-Villalba A, Zuschratter W, Bravo R, Herdegen T. 1995. Transection of rat fimbria-fornix induces lasting expression of c-Jun protein in axotomized septal neurons immunonegative for choline acetyltransferase and nitric oxide synthase. Exp Neurol 134:112-125.
6. Brown JM, Yamamoto BK. 2003. Effects of amphetamines on mitochondrial function: role of free radicals and oxidative stress. Pharmacol Ther 99:45-53.
7. Brunswick DJ, Benmansour S, Tejani-Butt SM, Hauptmann M. 1992. Effects of high-dose methamphetamine on monoamine uptake sites in rat brain measured by quantitative autoradiography. Synapse 11:287-293.
8. Cass WA. 2000. Attenuation and recovery of evoked overflow of striatal serotonin in rats treated with neurotoxic doses of methamphetamine. J Neurochem 74:1079-1085.
9. Cass WA, Manning MW. 1999. Recovery of presynaptic dopaminergic functioning in rats treated with neurotoxic doses of methamphetamine. J Neurosci 19:7653-7660.
10. Commins DL, Seiden LS. 1986. alpha-Methyltyrosine blocks methylamphetamine-induced degeneration in the rat somatosensory cortex. Brain Res 365:15-20.
11. Commins DL, Axt KJ, Vosmer G, Seiden LS. 1987a. Endogenously produced 5,6-dihydroxytryptamine may mediate the neurotoxic effects of para-chloroamphetamine. Brain Res 419:253-261.
12. Commins DL, Vosmer G, Virus RM, Woolverton WL, Schuster CR, Seiden LS. 1987b. Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain. J Pharmacol Exp Ther 241:338-345.
13. Cosi C, Guerin K, Marien M, Koek W, Rollet K. 2004. The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo. Brain Res 996:1-8.
14. Deng X, Wang Y, Chou J, Cadet JL. 2001. Methamphetamine causes widespread apoptosis in the mouse brain: evidence from using an improved TUNEL histochemical method. Brain Res Mol Brain Res 93:64-69.
15. Deng X, Jayanthi S, Ladenheim B, Krasnova IN, Cadet JL. 2002. Mice with partial deficiency of c-Jun show attenuation of methamphetamine-induced neuronal apoptosis. Mol Pharmacol 62:993-1000.
16. Dihne M, Block F, Korr H, Topper R. 2001. Time course of glial proliferation and glial apoptosis following excitotoxic CNS injury. Brain Res 902:178-189.
17. Eisch AJ, Marshall JF. 1998. Methamphetamine neurotoxicity: dissociation of striatal dopamine terminal damage from parietal cortical cell body injury. Synapse 30:433-445.
18. Eisch AJ, Gaffney M, Weihmuller FB, O'Dell SJ, Marshall JF. 1992. Striatal subregions are differentially vulnerable to the neurotoxic effects of methamphetamine. Brain Res 598:321-326.
19. Eisch AJ, O'Dell SJ, Marshall JF. 1996. Striatal and cortical NMDA receptors are altered by a neurotoxic regimen of methamphetamine. Synapse 22:217-225.
20. Eisch AJ, Schmued LC, Marshall JF. 1998. Characterizing cortical neuron injury with Fluoro-Jade labeling after a neurotoxic regimen of methamphetamine. Synapse 30:329-333.
21. Ferrer I, Blanco R, Carmona M, Puig B, Dominguez I, Vinals F. 2002. Active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates are differentially expressed following systemic administration of kainic acid to the adult rat. Acta Neuropathol (Berl) 103:391-407.
22. Hajnal A, Lenard L, Czurko A, Sandor P, Karadi Z. 1997. Distribution and time course of appearance of "dark" neurons and EEG activity after amygdaloid kainate lesion. Brain Res Bull 43:235-243.
23. Ham J, Eilers A, Whitfield J, Neame SJ, Shah B. 2000. c-Jun and the transcriptional control of neuronal apoptosis. Biochem Pharmacol 60:1015-1021.
24. Herdegen T, Leah JD 1998. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Brain Res Rev 28:370-490.
25. Herdegen T, Waetzig V. 2001a. AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration. Oncogene 20:2424-2437.
26. Herdegen T, Waetzig V. 2001b. The JNK and p38 signal transduction following axotomy. Restor Neurol Neurosci 19:29-39.
27. Herdegen T, Skene P, Bahr M. 1997. The c-Jun transcription factor: bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci 20:227-231.
28. Herdegen T, Claret FX, Kallunki T, Martin-Villalba A, Winter C, Hunter T, Karin M. 1998. Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J Neurosci 18:5124-5135.
29. Hotchkiss AJ, Gibb JW. 1980. Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain. J Pharmacol Exp Ther 214:257-262.
30. Hughes PE, Alexi T, Walton M, Williams CE, Dragunow M, Clark RG, Gluckman PD. 1999. Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system. Prog Neurobiol 57:421-450.
31. Imam SZ, Crow JP, Newport GD, Islam F, Slikker W, Jr., Ali SF. 1999. Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst. Brain Res 837:15-21.
32. Kita T, Takahashi M, Kubo K, Wagner GC, Nakashima T. 1999. Hydroxyl radical formation following methamphetamine administration to rats. Pharmacol Toxicol 85:133-137.
33. Kita T, Wagner GC, Nakashima T. 2003. Current research on methamphetamine-induced neurotoxicity: animal models of monoamine disruption. J Pharmacol Sci 92:178-195.
34. Kogan FJ, Nichols WK, Gibb JW. 1976. Influence of methamphetamine on nigral and striatal tyrosine hydroxylase activity and on striatal dopamine levels. Eur J Pharmacol 36:363-371.
35. Kuo YM, Chen HH, Shieh CC, Chuang KP, Cherng CG, Yu L. 2003. 4-Hydroxytamoxifen attenuates methamphetamine-induced nigrostriatal dopaminergic toxicity in intact and gonadetomized mice. J Neurochem 87:1436-1443.
36. La Voie MJ, Hastings TG. 1999a. Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine. J Neurosci 19:1484-1491.
37. LaVoie MJ, Hastings TG. 1999b. Peroxynitrite- and nitrite-induced oxidation of dopamine: implications for nitric oxide in dopaminergic cell loss. J Neurochem 73:2546-2554.
38. Leppa S, Saffrich R, Ansorge W, Bohman D. 1998. Differential regulation of c-Jun by ERK and JNK during PC 12 cell differentiation. Embo J 17:4404-4413.
39. Marshall JF, O'Dell SJ, Weihmuller FB. 1993. Dopamine-glutamate interactions in methamphetamine-induced neurotoxicity. J Neural Transm Gen Sect 91:241-254.
40. Mielke K, Brecht S, Dorst A, Herdegen T. 1999. Activity and expression of JNK1, p38 and ERK kinases, c-Jun N-terminal phosphorylation, and c-jun promoter binding in the adult rat brain following kainate-induced seizures. Neuroscience 91:471-483.
41. Miller DB, O'Callaghan JP. 1994. Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. J Pharmacol Exp Ther 270:752-760.
42. Nash JF, Yamamoto BK. 1992. Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine. Brain Res 581:237-243.
43. Nowak TS Jr, Ikeda J, Nakajima T. 1990. 70-kDa heat shock protein and c-fos gene expression after transient ischemia. Stroke 21:III 107-111.
44. O'Dell SJ, Marshall JF. 2000. Repeated administration of methamphetamine damages cells in the somatosensory cortex: overlap with cytochrome oxidase-rich barrels. Synapse 37:32-37.
45. O'Dell SJ, Marshall JF. 2002. Effects of vibrissae removal on methamphetamine-induced damage to rat somatosensory cortical neurons. Synapse 43:122-130.
46. O'Dell SJ, Weihmuller FB, Marshall JF. 1991. Multiple methamphetamine injections induce marked increases in extracellular striatal dopamine which correlate with subsequent neurotoxicity. Brain Res 564:256-260.
47. Pu C, Vorhees CV. 1993. Developmental dissociation of methamphetamine-induced depletion of dopaminergic terminals and astrocyte reaction in rat striatum. Brain Res Dev Brain Res 72:325-328.
48. Pu C, Broening HW, Vorhees CV. 1996. Effect of methamphetamine on glutamate-positive neurons in the adult and developing rat somatosensory cortex. Synapse 23:328-334.
49. Ricaurte GA, Schuster CR, Seiden LS. 1980. Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: a regional study. Brain Res 193:153-163.
50. Ricaurte GA, Guillery RW, Seiden LS, Schuster CR, Moore RY. 1982. Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain. Brain Res 235:93-103.
51. Saluja I, O'Regan MH, Song D, Phillis JW. 1999. Activation of cPLA2, PKC, and ERKs in the rat cerebral cortex during ischemia/reperfusion. Neurochem Res 24:669-677.
52. Schmued LC, Bowyer JF. 1997. Methamphetamine exposure can produce neuronal degeneration in mouse hippocampal remnants. Brain Res 759:135-140.
53. Schmued LC, Albertson C, Slikker W Jr. 1997. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 751:37-46.
54. Seiden LS, Commins DL, Vosmer G, Axt K, Marek G. 1988. Neurotoxicity in dopamine and 5-hydroxytryptamine terminal fields: a regional analysis in nigrostriatal and mesolimbic projections. Ann NY Acad Sci 537:161-172.
55. Smeal T, Binetruy B, Mercola DA, Birrer M, Karin M. 1991. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 354:494-496.
56. Smeal T, Hibi M, Karin M. 1994. Altering the specificity of signal transduction cascades: positive regulation of c-Jun transcriptional activity by protein kinase A. Embo J 13:6006-6010.
57. Sonsalla PK, Gibb JW, Hanson GR. 1986. Roles of D1 and D2 dopamine receptor subtypes in mediating the methamphetamine-induced changes in monoamine systems. J Pharmacol Exp Ther 238:932-937.
58. Sonsalla PK, Giovanni A, Sieber BA, Donne KD, Manzino L. 1992. Characteristics of dopaminergic neurotoxicity produced by MPTP and methamphetamine. Ann NY Acad Sci 648:229-238.
59. Stephans SE, Yamamoto BK. 1994. Methamphetamine-induced neurotoxicity: roles for glutamate and dopamine efflux. Synapse 17:203-209.
60. Sulzer D, Zecca L. 2000. Intraneuronal dopamine-quinone synthesis: a review. Neurotox Res 1:181-195.
61. Wagner GC, Ricaurte GA, Seiden LS, Schuster CR, Miller RJ, Westley J. 1980. Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine. Brain Res 181:151-160.
62. Weihmuller FB, O'Dell SJ, Marshall JF. 1993. L-dopa pretreatment potentiates striatal dopamine overflow and produces dopamine terminal injury after a single methamphetamine injection. Brain Res 623:303-307.
63. Wong-Riley M. 1979. Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res 171:11-28.
64. Yamamoto BK, Zhu W. 1998. The effects of methamphetamine on the production of free radicals and oxidative stress. J Pharmacol Exp Ther 287:107-114.
65. Yang DD, Kuan CY, Whitmarsh AJ, Rincon M, Zheng TS, Davis RJ, Rakic P, Flavell RA. 1997. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389:865-870.