4-Hydroxytamoxifen attenuates methamphetamine-induced nigrostriatal dopaminergic toxicity in intact and gonadetomized mice

Journal of Neurochemistry

Volumn 87, Issue 6, 2003, Pages 1436-1443

  Kuo, Yu Min ^a   Chen, Hsiang Hua ^a   Shieh, Chih Chang ^a   Chuang, Kuo Pin ^a   Cherng, Chianfang G ^b   Yu, Lung ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b DEPARTMENT OF ELECTRONIC ENGINEERING   (Taiwan)

Author keywords

Anti estrogen; Antioxidation; Dopamine; Neurotoxicity; Striatum

Indexed keywords

4 HYDROXYTAMOXIFEN; COPPER ZINC SUPEROXIDE DISMUTASE; DOPAMINE; METHAMPHETAMINE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BASAL BODY TEMPERATURE; CHEMOLUMINESCENCE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE BRAIN LEVEL; DOPAMINERGIC SYSTEM; DRUG EFFECT; FEMALE; GONADECTOMY; HYPERTHERMIA; MALE; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; STRIATE CORTEX;

ANIMALIA;

EID: 0347064335     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02089.x     Document Type: Article

References (44)

1. Agarwal V. R., Sinton C. M., Liang C., Fisher C., German D. C. and Simpson E. R. (2000) Upregulation of estrogen receptors in the forebrain of aromatases knockout (ArKO) mice. Mol. Cell Endocrinol. 162, 9-16.
2. Bowyer J. F., Davis D. L., Schmued L., Broening H. W., Newport G. D., Slikker W. J. and Holson R. R. (1994) Further studies of the role of hyperthermia in methamphetamine neurotoxicity. J. Pharmacol. Exper Ther. 268, 1571-1580.
3. Cadet J. L., Sheng P., Ali S. F., Rothman R., Carlson E. and Epstein C. (1994) Attenuation of methamphetamine-induced neurotoxicity in copper/zinc superoxide dismutase transgenic mice. J. Neurochem. 62, 380-383.
4. Cardoso C., Moreno A., Almeida L. and Lustodio J. (2002) 4-Hydroxytamoxifen induces slight uncoupling of mitochondrial oxidative phosphorylation system in relation to the deterious effects of tamoxifen. Toxicology 179, 221-232.
5. Daosukho C., Kiningham K., Kasarskis E. J., Ittarat W. and St Clair D. K. (2002) Tamoxifen enhancement of TNF-alpha induced MnSOD expression: modulation of NF-kappaB dimerization. Oncogene 21, 3603-3610.
6. Davidson C., Gow A. J., Lee T. H. and Ellinwood E. H. (2001) Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res. Rev. 36, 1-21.
7. De Vito M. J. and Wagner G. C. (1989) Methamphetamine-induced neuronal damage: a possible role for free radicals. Neuropharmacology 28, 1145-1150.
8. Deng X. and Cadet J. L. (2000) Methamphetamine-induced apoptosis is attenuated in the striata of copper-zinc superoxide dismutase transgenic mice. Brain Res. Mol. Brain Res. 83, 121-124.
9. Dluzen D. E. (1997) Estrogen decreases corpus striatal neurotoxicity in response to 6-hydroxydopamine. Brain Res. 767, 340-344.
10. Dluzen D. E. and McDermott J. L. (2002) Estrogen, anti-estrogen, and gender: differences in methamphetamine neurotoxicity. Ann. N.Y. Acad. Sci. 965, 136-156.
11. Dluzen D. E., McDermott J. L. and Liu B. (1996) Estrogen alters MPTP-induced neurotoxicity in female mice: effects on striatal dopamine concentrations and release. J. Neurochem. 66, 658-666.
12. Dluzen D. E., McDermott J. L. and Anderson L. I. (2001) Tamoxifen diminishes methamphetamine-induced striatal dopamine depletion in intact female and male mice. J. Neuroendocrinol. 13, 618-624.
13. Farfel G. M. and Seiden L. S. (1995) Role of hyperthermia in the mechanism of protection against toxicity: II. Experiments with methamphetamine, p-chloroamphetamine, fenfluramine, dizocilpine and dextromethorphan. J. Pharmacol. Exp. Ther. 272, 868-875.
14. Fleckenstein A. E., Metzger R. R., Wilkins D. G., Gibb J. W. and Hanson G. R. (1997) Rapid and reversible effects of methamphetamine on dopamine transporters. J. Pharmacol. Exp. Ther. 282, 834-838.
15. Gao X. and Dluzen D. E. (2001) Tamoxifen abolishes estrogen's neuroprotective effect upon methamphetamine neurotoxicity of the nigrostriatal dopaminergic system. Neuroscience 103, 385-394.
16. Ickenstein L. M. and Bandiera S. M. (2002) Persistent suppression of hepatic CYP2A1 expression and serum triiodothyronine levels by tamoxifen in intact female rats: dose-response analysis and comparison with 4-hydroxytamoxifen, fulvestrant (ICI 182,780), and 17beta-estradiol-3-benzoate. J. Pharmacol. Exp. Ther 302, 584-593.
17. Imam S. Z. and Ali S. F. (2000) Selenium, an antioxidant, attenuates methamphetamine-induced dopaminergic toxicity and peroxy-nitrite generation. Brain Res. 855, 186-191.
18. Imam S. Z., el-Yazal J., Newport G. D., Itzhak Y., Cadet J. L., Slikker W. Jr and Ali S. F. (2001) Methamphetamine-induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts. Ann. N.Y. Acad. Sci. 939, 366-380.
19. Kita T., Takahashi M., Kubo K., Wagner G. C. and Nakashima T. (1999) Hydroxyl radical formation following methamphetamine administration to rats. Pharmacol. Toxicol. 85, 133-137.
20. Kita T., Shimada K., Mastunari Y., Wagner G. C., Kubo K. and Nakashima T. (2000) Methamphetamine-induced striatal dopamine neurotoxicity and cyclooxygenase-2 protein expression in BALB/c mice. Neuropharmacology 39, 399-406.
21. LaVoie M. J. and Hastings T. G. (1999) Dopamine quinone formation and protein modification associated with the striatal neurotoxicity of methamphetamine: evidence against a role for extracellular dopamine. J. Neurosci. 19, 1484-1491.
22. Li Y., Zhu H., Kuppusamy P., Roubaud V., Zweier J. L. and Trush M. A. (1998) Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J. Biol. Chem. 273, 2015-2023.
23. Mandlekar S., Hebbar V., Christov K. and Kong A. N. (2000) Pharmacodynamics of tamoxifen and its 4-hydroxy and N-desmethyl metabolites: activation of caspases and induction of apoptosis in rat mammary tumors and in human breast cancer cell lines. Cancer Res. 60, 6601-6606.
24. Maragos W. F., Jakel R., Chesnut D., Pocernich C. B., Butterfield D. A., St Clair D. and Cass W. A. (2000) Methamphetamine toxicity is attenuated in mice that overexpress human manganese superoxide dismutase. Brain Res. 878, 218-222.
25. Marek G. J., Vosmer G. and Seiden L. S. (1990) Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons. Brain Res. 513, 274-279.
26. May F. E. and Westley B. R. (1987) Effects of tamoxifen and 4-hydroxytamoxifen on the pNR-1 and pNR-2 estrogen-regulated RNAs in human breast cancer cells. J. Biol. Chem. 262, 15894-15899.
27. Miller D. B., Ali S. F., O'Callaghan J. P. and Laws S. C. (1998) The impact of gender and estrogen on striatal dopaminergic neurotoxicity. Ann. N.Y. Acad. Sci. 844, 153-165.
28. Pu C., Fisher J. E., Cappon G. D. and Vorhees C. V. (1994) The effects of amfonelic acid, a dopamine uptake inhibitor, on methamphetamine-induced dopaminergic terminal degeneration and astrocytic response in rat striatum. Brain Res. 649, 217-224.
29. Ricaurte G. A., Guillery R. W., Seiden L. S., Schuster C. R. and Moore R. Y. (1982) Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain. Brain Res. 235, 93-103.
30. Sakamoto T., Eguchi H., Omoto Y., Ayabe T., Mori H. and Hayashi S. (2002) Estrogen receptor-mediated effects of tamoxifen on human endometrial cancer cells. Mol. Cell Endocrinol. 192, 93-104.
31. Simerly R. B., Chang C., Muramatsu M. and Swanson L. W. (1990) Distribution of androgen and estrogen receptor mRNA containing cells in the rat brain: an in situ hybridization study. J. Comp. Neurol. 294, 76-95.
32. Sonsalla P. K., Jochnowitz N. D., Zeevalk G. D., Oostveen J. A. and Hall E. D. (1996) Treatment of mice with methamphetamine produces cell loss in the substantia nigra. Brain Res. 738, 172-175.
33. Styles J. A., Davies A., Lim C. K., De Matteis F., Stanley L. A., White I. N., Yuan Z. X. and Smith L. L. (1994) Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s. Carcinogenesis 15, 5-9.
34. Thangaraju M., Vijayalakshmi T. and Sachdanandam P. (1994) Effect of tamoxifen on lipid peroxide and antioxidative system in postmenopausal women with breast cancer. Cancer 74, 78-82.
35. Thangaraju M., Ezhilarasi R. and Sachdanandam P. (1995) Effect of tamoxifen on erythrocyte membrane lipids, lipid peroxides, and antioxidative enzymes in breast cancer women. Cancer Biochem. Biophys. 14, 297-302.
36. Wagner G. C., Seiden L. S. and Schuster C. R. (1979) Methamphetamine-induced changes in brain catecholamines in rats and guinea pigs. Drug Alcohol Depend. 4, 435-438.
37. Wagner G. C., Ricaute G. A., Seiden L. S., Schuster C. R., Miller J. M. and Westly J. (1980) Long-lasting depletion of striatal DA and loss of DA uptake sites following the repeated administration of methamphetamine. Brain Res. 171, 151-160.
38. Wagner G. C., Tekirian T. L. and Cheo C. T. (1993) Sexual differences in sensitivity to methamphetamine toxicity. J. Neural. Transm. 93, 67-70.
39. Xie T., Tong L., Barrett T., Yuan J., Hatzidimitriou G., McCann U. D., Becker K. G., Donovan D. M. and Ricaurte G. A. (2002) Changes in gene expression linked to methamphetamine-induced dopaminergic neurotoxicity. J. Neurosci. 22, 274-283.
40. Yu Y.-L. and Wagner G. C. (1994) Influence of gonadal hormones on sexual differences in sensitivity to methamphetamine-induced neurotoxicity. J. Neural Transm. Park. Dis. Dement. Sect. 8, 215-221.
41. Yu L. and Liao P. C. (2000a) Sexual differences and estrous cycle in methamphetamine-induced dopamine and serotonin depletions in the striatum of mice. J. Neural. Transm. 107, 419-427.
42. Yu L. and Liao P. C. (2000b) Estrogen and progesterone distinctively modulate methamphetamine-induced dopamine and serotonin depletions in C57BL/6J mice. J. Neural. Transm. 107, 1139-1147.
43. Yu L., Cherng C. G. and Chen C. (2002b) Melatonin in concentrated ethanol and ethanol alone attenuate methamphetamine-induced dopamine depletions in C57BL/6J mice. J. Neural Transm. 109, 1477-1490.
44. Yu L., Kuo Y. M., Cherng C. G., Chen H. H. and Hsu C. H. (2002a) Ovarian hormones do not attenuate methamphetamine-induced dopaminergic neurotoxicity in mice gonadectomized at 4 weeks postpartum. Neuroendocrinology 75, 282-287.