Bcl-2 inhibitors potentiate the cytotoxic effects of radiation in Bcl-2 overexpressing radioresistant tumor cells

International Journal of Radiation Oncology Biology Physics

Volumn 61, Issue 2, 2005, Pages 517-528

  Hara, Takamitsu ^a   Omura Minamisawa, Motoko ^a   Chao, Cheng ^a   Nakagami, Yoshihiro ^a   Ito, Megumi ^a   Inoue, Tomio ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Antisense oligonucleotide; Apoptosis; Bcl 2; Radiosensitizer; Tetrocarcin A

Indexed keywords

BIOASSAY; BIOLOGICAL RADIATION EFFECTS; CELLS; ENZYME INHIBITION; OLIGOMERS; TOXICITY; TUMORS;

APOPTOTIC CELLS; CYTOTOXICITY; OLIGONUCLEOTIDES; RADIORESISTANT TUMOR CELLS;

RADIOTHERAPY;

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BLOCKING AGENT; PROTEIN BCL 2; PROTEIN BCL 2 INHIBITOR; RADIOSENSITIZING AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; INCUBATION TIME; IRRADIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION; RADIOSENSITIVITY; TUMOR CELL; WILD TYPE;

AMINOGLYCOSIDES; ANALYSIS OF VARIANCE; APOPTOSIS; CELL SURVIVAL; HELA CELLS; HUMANS; OLIGONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; RNA, MESSENGER; TUMOR STEM CELL ASSAY;

EID: 12844276074     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2004.10.008     Document Type: Article

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