A novel assay for discovery and characterization of pro-apoptotic drugs and for monitoring apoptosis in patient sera

Apoptosis

Volumn 8, Issue 3, 2003, Pages 263-268

  Biven K ^a   Erdal, H ^a   Hagg M ^a   Ueno, T ^a   Zhou, R ^a   Lynch, M ^b   Rowley, B ^b   Wood, J ^b   Zhang, C ^b   Toi, M ^c   Shoshan, M C ^a   Linder, S ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b BAYER CORPORATION   (United States)

^c TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

Author keywords

Apoptosis; Caspase; Cytokeratin 18; Drug discovery; Therapy

Indexed keywords

6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; 6 PROPANAMINE; CAMPTOTHECIN; CISPLATIN; CYTOKERATIN 18; CYTOTOXIC AGENT; DIANEMYCIN; ELLIPTICINE; MONOCLONAL ANTIBODY M30; PRO APOPTOTIC AGENT; PROTEIN P53; UNCLASSIFIED DRUG; WH 236; WH 237; WH 28; WH 411; WH 533; WH 802;

APOPTOSIS; ARTICLE; CELL DEATH; DRUG CYTOTOXICITY; DRUG SCREENING; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; PRIORITY JOURNAL; SERUM;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; ASPARTIC ACID; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HUMANS; KERATINS; MEMBRANE POTENTIALS; MITOCHONDRIA; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS; PEPTIDE FRAGMENTS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME;

EID: 12444342652     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023672805949     Document Type: Article

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