Comparative evaluation of the in vitro micronucleus test and the in vitro chromosome aberration test: Industrial experience

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 392, Issue 1-2, 1997, Pages 45-59

  Miller, Beate ^a   Albertini, Silvio ^b   Locher, Franziska ^c   Thybaud, Veronique ^d   Lorge, Elisabeth ^e  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c NOVARTIS PHARMA AG   (Switzerland)

^d SANOFI   (France)

^e INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

In vitro chromosome aberration test; In vitro micronucleus test; Routine genotoxicity screening

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; BLEOMYCIN; CIPROFLOXACIN; CLASTOGEN; CP 67804; CYCLOPHOSPHAMIDE; ENROFLOXACIN; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; MITOMYCIN C; MUTAGENIC AGENT; NALIDIXIC ACID; NORFLOXACIN; PROMUTAGEN; UNCLASSIFIED DRUG; WATER;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; BLOOD; CHO CELL; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CONTROLLED STUDY; DRUG COMPARISON; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERMETHOD COMPARISON; LYMPHOCYTE CULTURE; MICRONUCLEUS TEST; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL;

ANIMALS; CELLS, CULTURED; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; HUMANS; LYMPHOCYTES; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; REPRODUCIBILITY OF RESULTS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0030789581     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(97)00044-X     Document Type: Article

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