Improved growth response of antibody/receptor chimera attained by the engineering of transmembrane domain

Protein Engineering, Design and Selection

Volumn 17, Issue 10, 2004, Pages 715-719

  Kawahara, Masahiro ^a   Ogo, Yuko ^a   Ueda, Hiroshi ^a   Nagamune, Teruyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Antibody; Chimeric receptor; Cytokine receptor; Mutation; Transmembrane domain

Indexed keywords

ANTIBODIES; CELL MEMBRANES; GENES; GROWTH KINETICS; MUTAGENESIS;

CELL AMPLIFICATION; INTERCHAIN INTERACTION; RECEPTOR CHIMERA; RESIDUAL GROWTH; TRANSMEMBRANE (TM) DOMAIN;

ANTIGEN-ANTIBODY REACTIONS;

ANTIBODY; BOVINE SERUM ALBUMIN; CYTOKINE RECEPTOR; ERYTHROPOIETIN RECEPTOR; FLUORESCEIN; INTERLEUKIN 6; LEUCINE ZIPPER PROTEIN; LIGAND; RETROVIRUS VECTOR;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; CELL GROWTH; CELL STRAIN 7TD1; CHIMERA; CONTROLLED STUDY; DNA MODIFICATION; GENETICALLY MODIFIED CELL AMPLIFICATION; HYBRIDOMA CELL CULTURE; MOLECULAR INTERACTION; MOLECULAR MIMICRY; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSMEMBRANE DOMAIN;

ANIMALS; ANTIBODIES; CELL DIVISION; CELL LINE; HUMANS; MICE; MUTATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOKINE; RECOMBINANT FUSION PROTEINS;

ANIMALIA; BOVINAE; UNIDENTIFIED RETROVIRUS;

EID: 12444252157     PISSN: 17410126     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/gzh088     Document Type: Article

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