Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain

EMBO Journal

Volumn 18, Issue 12, 1999, Pages 3334-3347

  Constantinescu, Stefan N ^a   Liu, Xuedong ^a   Beyer, Wendy ^a,b   Fallon, Amy ^a   Shekar, Srinivasan ^c   Henis, Yoav I ^a,d   Smith, Steven O ^c   Lodish, Harvey F ^a,e  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b KENYON COLLEGE   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Epo receptor signaling; Red cell formation; SFFV gp55 env proteins; Transmembrane coiled coil interactions

Indexed keywords

ERYTHROPOIETIN RECEPTOR; ISOLEUCINE; LEUCINE; MUTANT PROTEIN; SERINE; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FETUS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; RECEPTOR SENSITIVITY; RECEPTOR UPREGULATION; SPLEEN FOCUS FORMING VIRUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANEMIA; ANIMALS; BINDING SITES; CELL LINE; CELL MEMBRANE; DIMERIZATION; ERYTHROCYTES; ERYTHROPOIETIN; HUMANS; METHYLATION; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POLYCYTHEMIA; RECEPTORS, ERYTHROPOIETIN; SIGNAL TRANSDUCTION; STEM CELLS; TRANSFECTION; VIRAL ENVELOPE PROTEINS;

EID: 0033564715     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.12.3334     Document Type: Article

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