Phagocytes: Mechanisms of inflammation and tissue destruction

Rheumatic Disease Clinics of North America

Volumn 30, Issue 1, 2004, Pages 19-39

  Liu, Hongtao ^a,b   Pope, Richard M ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; GLYCOPROTEIN; GROWTH FACTOR; LIGAND; MESSENGER RNA; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PADGEM PROTEIN; REACTIVE OXYGEN METABOLITE;

ANTIGEN ANTIBODY COMPLEX; APOPTOSIS; CELL ACTIVITY; CELL ADHESION; CELL MIGRATION; CLEARANCE; CYTOKINE RELEASE; HUMAN; IMMUNITY; INFLAMMATION; LEUKOCYTE ACTIVATION; LYSOSOME; MACROPHAGE; MEDIATOR RELEASE; NEUTROPHIL; PATHOGENESIS; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN MOTIF; REVIEW; TISSUE INJURY; TRANSCRIPTION REGULATION; VASCULITIS;

EID: 1242340409     PISSN: 0889857X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-857X(03)00107-8     Document Type: Review

References (74)

1. Worthylake R.A., Burridge K. Leukocyte transendothelial migration: orchestrating the underlying molecular machinery. Curr Opin Cell Biol. 13:2001;569-577.
2. Johnson-Leger C., Aurrand-Lions M., Imhof B.A. The parting of the endothelium: miracle, or simply a junctional affair? J Cell Sci. 113(Pt 6):2000;921-933.
3. McEver R.P. Selectins: lectins that initiate cell adhesion under flow. Curr Opin Cell Biol. 14:2002;581-586.
4. Moore K.L., Patel K.D., Bruehl R.E., Li F., Johnson D.A., Lichenstein H.S.et al. P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin. J Cell Biol. 128:1995;661-671.
5. McEver R.P., Cummings R.D. Role of PSGL-1 binding to selectins in leukocyte recruitment. J Clin Invest. 100:1997;S97-S103.
6. Xia L., Sperandio M., Yago T., McDaniel J.M., Cummings R.D., Pearson-White S.et al. P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. J Clin Invest. 109:2002;939-950.
7. Ramachandran V., Yago T., Epperson T.K., Kobzdej M.M., Nollert M.U., Cummings R.D.et al. Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow. Proc Natl Acad Sci USA. 98:2001;10166-10171.
8. Zimmerman G.A. Two by two: the pairings of P-selectin and P-selectin glycoprotein ligand 1. Proc Natl Acad Sci USA. 98:2001;10023-10024.
9. Lindemann S., Tolley N.D., Eyre J.R., Kraiss L.W., Mahoney T.M., Weyrich A.S. Integrins regulate the intracellular distribution of eukaryotic initiation factor 4E in platelets. A checkpoint for translational control. J Biol Chem. 276:2001;33947-33951.
10. Mahoney T.S., Weyrich A.S., Dixon D.A., McIntyre T., Prescott S.M., Zimmerman G.A. Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes. Proc Natl Acad Sci USA. 98:2001;10284-10289.
11. Zhou Z., Penn M.S., Forudi F., Zhou X., Tarakji K., Topol E.J.et al. Administration of recombinant P-selectin glycoprotein ligand Fc fusion protein suppresses inflammation and neointimal formation in Zucker diabetic rat model. Arterioscler Thromb Vasc Biol. 22:2002;1598-1603.
12. Hicks A.E., Leppanen A., Cummings R.D., McEver R.P., Hellewell P.G., Norman K.E. Glycosulfopeptides modeled on P-selectin glycoprotein ligand 1 inhibit P-selectin-dependent leukocyte rolling in vivo. FASEB J. 16:2002;1461-1462.
13. Molenaar T.J., Appeldoorn C.C., de Haas S.A., Michon I.N., Bonnefoy A., Hoylaerts M.F.et al. Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists. Blood. 100:2002;3570-3577.
14. Laudanna C., Kim J.Y., Constantin G., Butcher E. Rapid leukocyte integrin activation by chemokines. Immunol Rev. 186:2002;37-46.
15. Johnston B., Butcher E.C. Chemokines in rapid leukocyte adhesion triggering and migration. Semin Immunol. 14:2002;83-92.
16. Ley K. Integration of inflammatory signals by rolling neutrophils. Immunol Rev. 186:2002;8-18.
17. Zhou M., Brown E.J. Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst. J Exp Med. 178:1993;1165-1174.
18. Rossetti G., Collinge M., Bender J.R., Molteni R., Pardi R. Integrin-dependent regulation of gene expression in leukocytes. Immunol Rev. 186:2002;189-207.
19. Piali L., Hammel P., Uherek C., Bachmann F., Gisler R.H., Dunon D.et al. CD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endothelium. J Cell Biol. 130:1995;451-460.
20. Buckley C.D., Doyonnas R., Newton J.P., Blystone S.D., Brown E.J., Watt S.M.et al. Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1. J Cell Sci. 109(Pt 2):1996;437-445.
21. Muller W.A., Weigl S.A., Deng X., Phillips D.M. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med. 178:1993;449-460.
22. Martin-Padura I., Lostaglio S., Schneemann M., Williams L., Romano M., Fruscella P.et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol. 142:1998;117-127.
23. de Fougerolles A.R., Chi-Rosso G., Bajardi A., Gotwals P., Green C.D., Koteliansky V.E. Global expression analysis of extracellular matrix-integrin interactions in monocytes. Immunity. 13:2000;749-758.
24. de Fougerolles A.R., Koteliansky V.E. Regulation of monocyte gene expression by the extracellular matrix and its functional implications. Immunol Rev. 186:2002;208-220.
25. Kobayashi S.D., Voyich J.M., Buhl C.L., Stahl R.M., DeLeo F.R. Global changes in gene expression by human polymorphonuclear leukocytes during receptor-mediated phagocytosis: cell fate is regulated at the level of gene expression. Proc Natl Acad Sci USA. 99:2002;6901-6906.
26. Hurst S.M., Wilkinson T.S., McLoughlin R.M., Jones S., Horiuchi S., Yamamoto N.et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity. 14:2001;705-714.
27. Kobayashi H., Ohshima S., Nishioka K., Yamaguchi N., Umeshita-Sasai M., Ishii T.et al. Antigen induced arthritis (AIA) can be transferred by bone marrow transplantation: evidence that interleukin 6 is essential for induction of AIA. J Rheumatol. 29:2002;1176-1182.
28. Boe A., Baiocchi M., Carbonatto M., Papoian R., Serlupi-Crescenzi O. Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis. Cytokine. 11:1999;1057-1064.
29. Alonzi T., Fattori E., Lazzaro D., Costa P., Probert L., Kollias G.et al. Interleukin 6 is required for the development of collagen-induced arthritis. J Exp Med. 187:1998;461-468.
30. Ohshima S., Saeki Y., Mima T., Sasai M., Nishioka K., Nomura S.et al. Interleukin 6 plays a key role in the development of antigen-induced arthritis. Proc Natl Acad Sci USA. 95:1998;8222-8226.
31. Choy E.H., Isenberg D.A., Garrood T., Farrow S., Ioannou Y., Bird H.et al. Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial. Arthritis Rheum. 46:2002;3143-3150.
32. Nishimoto N., Yoshizaki K., Maeda K., Kuritani T., Deguchi H., Sato B.et al. Toxicity, pharmacokinetics, and dose-finding study of repetitive treatment with the humanized anti-interleukin 6 receptor antibody MRA in rhematoid arthritis Phase I/II clinical study. J Rheumatol. 30(7):2003;1426-1435.
33. Ji H., Ohmura K., Mahmood U., Lee D.M., Hofhuis F.M., Boackle S.A.et al. Arthritis critically dependent on innate immune system players. Immunity. 16:2002;157-168.
34. Nieto A., Caliz R., Pascual M., Mataran L., Garcia S., Martin J. Involvement of Fcgamma receptor IIIA genotypes in susceptibility to rheumatoid arthritis. Arthritis Rheum. 43:2000;735-739.
35. Kimberly R.P., Wu J., Gibson A.W., Su K., Qin H., Li X.et al. Diversity and duplicity: human FCgamma receptors in host defense and autoimmunity. Immunol Res. 26:2002;177-189.
36. Savill J., Dransfield I., Gregory C., Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol. 2:2002;965-975.
37. van Lent P.L., Licht R., Dijkman H., Holthuysen A.E., Berden J.H., van den Berg W.B. Uptake of apoptotic leukocytes by synovial lining macrophages inhibits immune complex-mediated arthritis. J Leukoc Biol. 70:2001;708-714.
38. Harper L., Ren Y., Savill J., Adu D., Savage C.O. Antineutrophil cytoplasmic antibodies induce reactive oxygen-dependent dysregulation of primed neutrophil apoptosis and clearance by macrophages. Am J Pathol. 157:2000;211-220.
39. Taylor P.R., Carugati A., Fadok V.A., Cook H.T., Andrews M., Carroll M.C.et al. A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med. 192:2000;359-366.
40. Vieira O.V., Botelho R.J., Grinstein S. Phagosome maturation: aging gracefully. Biochem J. 366:2002;689-704.
41. Fossati G., Moots R.J., Bucknall R.C., Edwards S.W. Differential role of neutrophil Fcgamma receptor IIIB (CD16) in phagocytosis, bacterial killing, and responses to immune complexes. Arthritis Rheum. 46:2002;1351-1361.
42. Lei B., DeLeo F.R., Hoe N.P., Graham M.R., Mackie S.M., Cole R.L.et al. Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis. Nat Med. 7:2001;1298-1305.
43. Babior B.M. Phagocytes and oxidative stress. Am J Med. 109:2000;33-44.
44. Bogdan C., Rollinghoff M., Diefenbach A. Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr Opin Immunol. 12:2000;64-76.
45. Parente L., Perretti M. Advances in the pathophysiology of constitutive and inducible cyclooxygenases: two enzymes in the spotlight. Biochem Pharmacol. 65:2003;153-159.
46. Lawrence T., Willoughby D.A., Gilroy D.W. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol. 2:2002;787-795.
47. Pope R.M., Perlman H. Rheumatoid Arthritis. Tsokas G.C. Principles of molecular rheumatology. 2000;325-361 Humana Press, Totowa (NJ).
48. Martel-Pelletier J., Welsch D.J., Pelletier J.P. Metalloproteases and inhibitors in arthritic diseases. Best Pract Res Clin Rheumatol. 15:2001;805-829.
49. Muller Kobold A.C., van der Geld Y.M., Limburg P.C., Tervaert J.W., Kallenberg C.G. Pathophysiology of ANCA-associated glomerulonephritis. Nephrol Dial Transplant. 14:1999;1366-1375.
50. Weidner S., Neupert W., Goppelt-Struebe M., Rupprecht H.D. Antineutrophil cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro. Arthritis Rheum. 44:2001;1698-1706.
51. Harper L., Radford D., Plant T., Drayson M., Adu D., Savage C.O. IgG from myeloperoxidase-antineutrophil cytoplasmic antibody-positive patients stimulates greater activation of primed neutrophils than IgG from proteinase 3-antineutrophil cytosplasmic antibody-positive patients. Arthritis Rheum. 44:2001;921-930.
52. Yamanishi Y., Boyle D.L., Rosengren S., Green D.R., Zvaifler N.J., Firestein G.S. Regional analysis of p53 mutations in rheumatoid arthritis synovium. Proc Natl Acad Sci USA. 99:2002;10025-10030.
53. Yamashiro S., Kamohara H., Wang J.M., Yang D., Gong W.H., Yoshimura T. Phenotypic and functional change of cytokine-activated neutrophils: inflammatory neutrophils are heterogeneous and enhance adaptive immune responses. J Leukoc Biol. 69:2001;698-704.
54. Scapini P., Nardelli B., Nadali G., Calzetti F., Pizzolo G., Montecucco C.et al. G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med. 197:2003;297-302.
55. Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 3:2003;23-35.
56. Mosser D.M. The many faces of macrophage activation. J Leukoc Biol. 73:2003;209-212.
57. Boehm U., Klamp T., Groot M., Howard J.C. Cellular responses to interferon-gamma. Annu Rev Immunol. 15:1997;749-795.
58. Bosisio D., Polentarutti N., Sironi M., Bernasconi S., Miyake K., Webb G.R.et al. Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood. 99:2002;3427-3431.
59. Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol. 1:2001;135-145.
60. Andonegui G., Goyert S.M., Kubes P. Lipopolysaccharide-induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels. J Immunol. 169:2002;2111-2119.
61. Gerber J.S., Mosser D.M. Reversing lipopolysaccharide toxicity by ligating the macrophage Fc gamma receptors. J Immunol. 166:2001;6861-6868.
62. Donnelly R.P., Dickensheets H., Finbloom D.S. The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J Interferon Cytokine Res. 19:1999;563-573.
63. Joyce D.A., Gibbons D.P., Green P., Steer J.H., Feldmann M., Brennan F.M. Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes. Eur J Immunol. 24:1994;2699-2705.
64. Lang R., Rutschman R.L., Greaves D.R., Murray P.J. Autocrine deactivation of macrophages in transgenic mice constitutively overexpressing IL-10 under control of the human CD68 promoter. J Immunol. 168:2002;3402-3411.
65. Pilette C., Ouadrhiri Y., Van Snick J., Renauld J.C., Staquet P., Vaerman J.P.et al. IL-9 inhibits oxidative burst and TNF-alpha release in lipopolysaccharide-stimulated human monocytes through TGF-beta. J Immunol. 168:2002;4103-4111.
66. Gratchev A., Guillot P., Hakiy N., Politz O., Orfanos C.E., Schledzewski K.et al. Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3. Scand J Immunol. 53:2001;386-392.
67. Koch R.M., Roche N.S., Parks W.T., Ashcroft G.S., Letterio J.J., Roberts A.B. Incisional wound healing in transforming growth factor-beta1 null mice. Wound Repair Regen. 8:2000;179-191.
68. Glick A., Popescu N., Alexander V., Ueno H., Bottinger E., Yuspa S.H. Defects in transforming growth factor-beta signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes. Proc Natl Acad Sci USA. 96:1999;14949-14954.
69. Berrebi D., Bruscoli S., Cohen N., Foussat A., Migliorati G., Bouchet-Delbos L.et al. Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10. Blood. 101:2003;729-738.
70. Katsikis P.D., Chu C.Q., Brennan F.M., Maini R.N., Feldmann M. Immunoregulatory role of interleukin 10 in rheumatoid arthritis. J Exp Med. 179:1994;1517-1527.
71. Firestein G.S., Manning A.M. Signal transduction and transcription factors in rheumatic disease. Arthritis Rheum. 42:1999;609-621.
72. Bondeson J., Foxwell B., Brennan F., Feldmann M. Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci USA. 96:1999;5668-5673.
73. Clark A. Post-transcriptional regulation of pro-inflammatory gene expression. Arthritis Res. 2:2000;172-174.
74. Gracie J.A., Leung B.P., McInnes I.B. Novel pathways that regulate tumor necrosis factor-alpha production in rheumatoid arthritis. Curr Opin Rheumatol. 14:2002;270-275.