Abnormalities in the reproductive health of flounder Platichthys flesus exposed to effluent from a sewage treatment works

Marine Pollution Bulletin

Volumn 34, Issue 1, 1997, Pages 34-41

  Lye, C M ^a   Frid, C L J ^a   Gill, M E ^a   McCormick, D ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; VITELLOGENIN;

ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ESTUARY; FEMALE; FLATFISH; GENITAL MALFORMATION; GEOGRAPHIC DISTRIBUTION; GONAD; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; REPRODUCTION; REPRODUCTIVE TOXICITY; SEWAGE TREATMENT PLANT; TESTIS; UNITED KINGDOM;

PLATICHTHYS FLESUS; PLEURONECTOIDEI;

ABNORMALITIES; FLOUNDER; OESTROGENIC SUBSTANCE; OESTROGENIC SUBSTANCES; POLLUTION; POLLUTION EFFECTS; REPRODUCTION; SEWAGE;

UK, ENGLAND;

EID: 0030621165     PISSN: 0025326X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0025-326X(96)00061-6     Document Type: Article

References (78)

1. Ahel, M., Giger, W. & Schaffner, C. (1994). Behaviour of alkylphenol polyethoxylate surfactants in the aquatic environment. II. Occurrence and transformation in rivers. Wat. Res. 28, 1143-1152.
2. Barr, W. A. (1963). The endocrine control of the sexual cycle in the plaice, Pleuronectes platessa L. III. The endocrine control of spermatogenesis. Gen. Comp. Endocrinol. 3, 216-225.
3. Billard, R., Breton, R. & Richard, M. (1981). On the inhibitory effect of some steroids on spermatogenesis in adult rainbow trout (Salmo gairdneri). Can. J. Zool. 59, 1379-1487.
4. Bitman, J. & Cecil, H. C. (1970). Estrogenic activity of DDT analogs and polychlorinated biphenyls. J. Agr. Food Chem. 18, 1108-1112.
5. Blomquist, G., Roos, A., Jensen, S., Bignert, A. & Olsson, M. (1992). Concentrations of DDTs and PCBs in seals from Swedish and Scottish Waters. Ambio 21, 539-545.
6. Bradford, M. M. (1976). A rapid and sensitive method for the quantification of microgram quantities utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-257.
7. Brennan, M. D. & Mahowald, A. P. (1982). Phosphorylation of the vitellogenin polypeptides of Drosophila melanogaster. Insect. Biochem. 12, 669-673.
8. Bromage, N. R. & Cumaranatunga, R. (1988). Egg production in the rainbow trout. Rec. Adv. Aquacult. 3, 65-138.
9. Brotons, J. A., Olea-Serrano, M. F., Villalobos, M., Pedraza, V. & Olea, N. (1995). Xenoestrogens released from lacquer coatings in food cans. Environ. Health Perspect. 103, 608-613.
10. Bryan, G. W., Langston, W. J., Hummerstone, L. G. & Burt, G. R. (1985). A guide to the assessment of heavy-metal contamination in estuaries using biological indicators. Mar. biol. Ass. U.K. Occ. Publ. 4, 92.
11. Bulger, W. H. & Kupfer, D. (1985). Estrogenic activity of pesticides and other xenobiotics on the uterus and male reproductive tract. In Endocrine Toxicology (J. A. Thomas, K. S. Korach & J. A. McLachlan, eds), pp. 1-33. Raven Press, New York.
12. Campbell, C. M. & Idler, D. R. (1976). Hormonal control of vitellogenesis in hypophysectomized winter flounder Pseudopleuronectes americanus Walbum. Gen. Comp. Endocrinol. 28, 143-150.
13. Campbell, C. M. & Idler, D. R. (1980). Characterisation of an estradiol-induced protein from rainbow trout plasma as vitellogenin by the composition and radioimmunological cross-reactivity to other yolk fractions. Biol. Reprod. 22, 605-617.
14. CES (1993). Uses, Fate and Entry to the Environment of Nonyl Ethoxylates. Consultants in Environmental Sciences Ltd (for the Department of Environment, UK), Beckenham, Kent.
15. Clemens, M. J. (1978). Regulation of egg protein synthesis by steroid hormones. Prog. Biophys. Mol. Biol. 28, 71-108.
16. Colborn, T. & Clement, C. (1992). Chemically-Induced Alterations in Sexual and Functional Development: The Human and Wildlife Conncection. Princeton Scientific, Princeton, New Jersey.
17. Colborn, T., vom Saal, F. S. & Soto, A. M. (1993). Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 101, 378-384.
18. Denison, M. S., Chambers, M. S. & Yarbrough, J. D. (1981). Persistent vitellogenin-like protein and binding to DDT in the serum of insecticide-resistent mosquito fish (Gambusia affinis). Comp. Biochem. Physiol. 69C, 109-112.
19. DiMario, P. J., Warren, T. G. & Mahowald, A. P. (1987). The purification and in vitro phosphorylation of vitellogenin from Drosophila melanogaster. Insect. Biochem. 17, 1187-1192.
20. Egami, N. (1955). Effect of estrogen and androgen on the weight and structure of the liver of the fish Oryzias latipez. Annot. Zool. Jpn. 28, 79-85.
21. Ekelund, R., Bergman, Å., Granmo, Å. & Berggren, M. (1990). Bioaccumulation of 4-nonylphenol in marine animals - a reevaluation. Environ. Poll. 64, 107-120.
22. Emmersen, B. K. & Petersen, I. M. (1976). Natural occurrence and experimental induction by estradiol 17β, of a lipophosphoprotein (vitellogenin) in flounder (Platichthys flesus L.). Comp. Biochem. Physiol. 54B, 443-446.
23. Emmersen, B. K. & Emmersen, J. (1976). Protein, RNA, DNA metabolism in relation to ovarian vitellogenic growth in the flounder (Platichthys flesus L.). Comp. Biochem. Physiol. 55B, 315-321.
24. Facemire, C. F., Gross, T. S. & Guillette, L. J., Jr (1995). Reproductive impairment in the Florida panther: nature or nurture? Environ. Health Perspect. 103 Suppl 4, 79-86.
25. Fagerlund, U. H. M. & McBride, J. R. (1975). Growth increments and some flesh and gonad characteristics of juvenile coho salmon receiveing diets supplemented with 17α-methyltestosterone. J. Fish Biol. 7, 305-314.
26. Fagerlund, U. H. M. & McBride, J. R. (1977). Effect of 17α-methyltestosterone on growth, gonad development, external features and proximate composition of muscle of steelhead trout, coho and pink salmon. Fisheries and Marine Service Technical Report, No. 716, pp. 37. Research and Resource Services, West Vancouver, British Coloumbia.
27. Giger, W., Brunner, P. H. & Schaffner, C. (1984). 4-nonylphenol in sewage sludge: accumulation of toxic metabolites from nonionic surfactants. Science 225, 623-625.
28. Giger, W., Ahel, M., Koch, M., Laubscher, H. U., Schaffner, C. S. & Schneider, J. (1987). Behaviour of alkylphenol polyethoxylate surfactants and of nitrilotriacetate in sewage treatment. Wat. Sci. Tech. 19, 449-460.
29. Gorski, J., Furlow, J. D., Murdoch, F. E., Fritsch, M., Kaneko, K., Ying, D. & Malayer, J. R. (1993). Perturbations in the model of estrogen receptor regulation of gene expression. Biol. Reprod. 48, 8-14.
30. Grier, H. J. (1981). Cellular organization of the testis and spermatogenesis in fishes. Amer. Zool. 21, 345-357.
31. Guillette, L. J., Jr, Gross, T. S., Masson, G. R., Matter, J. M., Percival, H. F. & Woodward, A. R. (1994). Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ. Health Perspect. 102, 680-688.
32. Harries, J. E., Jobling, S., Matthiessen, P., Sheahan, D. A. & Sumpter, J. P. (1995). Effects on trace organics on fish - phase 2. Publ. on behalf of Dep. of Environment (DoE) by Foundation for Water Research (FWR), pp. 90. Allen House, The Listons, Marlow, Bucks. FR/D 0022.
33. Harrison, P. T. C., Humfrey, C. D. N., Litchfield, M., Peakall, D. & Shuker, L. K. (1995). Environmental Oestrogens: Consequences to Human and Wildlife. Institute for Environment and Health, University of Leicester, Leicester.
34. Heppell, S. A., Denslow, N. D., Folmar, L. C. & Sullivan, C. V. (1995). Universal assay of vitellogenin as a biomarker for environmental estrogens. Environ. Health Perspect. 103 (Suppl 7), 9-15.
35. Hickey, E. D. & Wallace, R. A. (1974). A study of the vitellogenic protein in the serum of oestrogen-treated Ictalurus nebulosus. Biol. Bull. 147, 481-493.
36. Janssen, P. (1996). Reproduction of the flounder, P Latichthys flesus (L), in relation to environmental pollution: steroids and vitellogenesis. Doctoral thesis, University of Utrecht, Faculty of Biology, The Netherlands.
37. Jobling, S. & Sumpter, J. P. (1993). Detergent components in sewage effluent are weakly oestrogenic to fish: an in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquatic Toxicol. 27, 361-372.
38. Jobling, S., Reynolds, T., White, R., Parker, M. G. & Sumpter, J. P. (1995). A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environ. Health Perspect. 103, 582-587.
39. Johnson, L. L., Casillas, E., Myers, M. S., Rhodes, L. D. & Olson, O. P. (1991). Patterns of oocyte development and related changes in plasma 17β estradiol, vitellogenin and plasma chemistry in English sole Parophrys vetulus Girard. J. Exp. Mar. Biol. Ecol. 152, 161-185.
40. Kime, D. E. (1995). The effect of pollution on reproduction in fish. Rev. Fish. Biol. Fisheries 5, 52-96.
41. Köhler, A., Harms, U. & Luckas, B. (1986). Accumulation of organochlorines and mercury in flounder - an approach to pollution assessment. Helgoländer Meeresunters. 40, 431-440.
42. Field, B., Selub, M. & Hughes, C. L. (1990). Reproductive effects of environmental agents. Sem. Reprod. Endocrinol. 8, 44-54.
43. Laemlli, U. K. & Favre, M. (1973). Maturation of the head of bacteriophage T4. J. Mol. Biol. 80, 575-599.
44. Medda, A. K., Dasmahapatra, A. K. & Ray, A. K. (1980). Effect of estrogen and testosterone on the protein and nucleic acid contents of liver, muscle and gonad and plasma protein content of male and female (vitellogenic and nonvitellogenic) singi fish, Heteropneustes fossilis Bloch. Gen. Comp. Endocrinol. 42, 427-436.
45. McLachlan, J. A. (1981). Estrogens in the Environment. Elsevier North Holland Inc., New York.
46. McLachlan, J. A. (1985). Estrogens in the Environment. II. Influences of Development. Elsevier Science, New York.
47. Nagahama, Y. (1983). The functional morphology of teleost gonads. In Fish Physiology Vol. IXA. Reproduction (W. S. Hoar, D. J. Randall & E. M. Donaldson, eds), pp. 223-275. Academic Press, London.
48. Nagler, J. J. & Idler, D. R. (1987). Evidence for another yolk precursor protein, distinct from vitellogenin, in winter flounder (Pseudopleuronectes americanus). In Proceedings of the Third International Symposium on Reproductive Physiology of Fish (D. R. Idler, L. W. Crim & J. M. Walsh, eds), pp. 209-210. St John's, Newfoundland, Canada.
49. Naylor, C. G. (1992). Environmental fate of alkylphenol ethoxylates. Soap Cosmet. Chem. Spec. Aug., 27-32.
50. Ng, T. B. & Idler, D. R. (1983). Yolk formation and differentiation in teleost fishes. In Fish Physiology Vol. IXA Reproduction (W. S. Hoar, D. J. Randall & E. M. Donaldson, eds), pp. 373-404. Academic Press, London.
51. NRA (1994). Derwent and Cumbria coast catchment management plan consultation report, 149 pp. National Rivers Authority, North West Region, Carlisle, UK.
52. NRA (1995). Eden and Solway coast catchment management plan consultation report. National Rivers Authority, 102 pp. North West Region, Carlisle, UK.
53. Pelissero, C., Cuisset, B. & Le Menn, F. (1989). The influence of sex steroid in commercial fish meals and fish diets on plasma concentrations of estrogens and vitellogenin in cultured siberian sturgeon (Acipenser baeri). Aquat. Living Resour. 2, 161-168.
54. Pelissero, C., Bennetau, B., Babin, P., Le Menn, F. & Dunogues, J. (1991). The estrogenic activity of certain phytoestrogens in the siberian sturgeon (Acipenser baeri). J. Steroid Biochem. Molec. Biol. 38, 293-299.
55. Pelissero, C., Flouriot, B., Bennetau, B., Dunogues, J., Le Gac, F. & Sumpter, J. P. (1993). Vitellogenin synthesis in cultured hepatocytes: an in vitro test for the estrogenic potency of chemicals. J. Steroid Biochem. Molec. Biol. 44, 263-272.
56. Pereira, J. J., Ziskowski, J., Mercaldo-Allen, R., Kuropat, C., Luedke, D. & Gould, E. (1992). Vitellogenin in winter flounder (Pleuronectes americanus) from Long Island Sound and Boston harbor. Estuaries 15, 289-297.
57. Pereira, J. J., Mercaldo-Allen, R., Kuropat, C., Luedke, D. & Sennefelder, G. (1993). Effect of cadmium accumulation on serum vitellogenin levels and hepatosomatic and gonadosomatic indices of winter flounder (Pleuronectes americanus). Arch. Environ. Contam. Toxicol. 24, 427-431.
58. Plack, P. A., Pritchard, D. J. & Fraser, N. W. (1971). Egg proteins in cod serum. Natural occurrence and induction by injections of oestradiol 3-benzoate. Biochem. J. 121, 847-856.
59. Purdom, C. E., Hardiman, P. A., Bye, V. J., Eno, N. C., Tyler, C. R. & Sumpter, J. P. (1994). Estrogenic effects on effluents from sewage treatment works. Chem. Ecol. 8, 275-285.
60. Reimann, E. M. & Beham, R. A. (1983). Catalytic subunit of cAMP-dependent protein kinase. Methods Enzymol. 99, 51-55.
61. Sharpe, R. M., Fisher, J. S., Millar, M. M. & Sumpter, J. P. (1995). Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production. Environ. Health Pespeet. 12, 1136-1143.
62. Sheahan, D. A., Bucke, D., Matthiessen, P., Sumpter, J. P., Kirby, M. F., Neall, P. & Waldock, M. (1994). The effects of low levels of 17α-ethynylestradiol upon plasma vitellogenin levels in male and female rainbow trout Oncorhynchus mykiss held at two acclimation temperatures. In Sublethal and Chronic Effects of Pollutants on Freshwater (R. Muller & R. Lloyd, eds), pp. 99-112. Fishing News Books, Oxford, by arrangement with FAO, Rome.
63. Shore, L. S., Gurevitz, M. & Shemesh, M. (1993). Estrogen as an environmental pollutant. Bull. Environ. Contam. Toxicol. 51, 361-366.
64. Silversand, C. & Haux, C. (1989). Isolation of turbot (Scophthalmus maximus) vitellogenin by high-performance anion-exchange chromatography. J. Chromatogr. 478, 387-397.
65. Soto, A. M., Justicia, H., Wray, J. W. & Sonnenschein, C. (1991). p-nonylphenol: an estrogenic xenobiotic released from modified polystyrene. Environ. Health Perspect. 92, 167-173.
66. Soto, A. M., Lin, T.-M., Justicia, H., Silvia, R. M. & Sonnenschein, C. (1992). An in culture bioassay to assess the estrogenicity of xenobiotics (e-screen). In Chemically-Induced Alterations in Sexual and Functional Development: the Wildlife/Human Connection (T. Colborn & C. Clement, eds), pp. 295-309. Princeton Scientific, Princeton, New Jersey.
67. Soto, A. M., Sonnenschein, C., Chung, K. L., Fernandez, M. F., Olea, N. & Serrano, F. O. (1995). The E-screen assay as a tool to identify oestrogens: an update on oestrogenic environmental pollutants. Environ. Health Perspect. 103 (Suppl 7), 113-122.
68. Specker, J. L. & Sullivan, C. V. (1994). Vitellogenesis in fishes: status and perspectives. In Perspectives in Comparative Endocrinology (K. G. Davey, R. E. Peter & S. S. Tobe, eds), pp. 304-315. National Research Council of Canada, Ottawa.
69. Sumpter, J. P. & Jobling, S. (1995). Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Perspect. 103 (Suppl 7), 173-178.
70. Swedmark, M., Braaten, B., Emanuelsson, E. & Granmo, Å. (1971). Biological effects of surface active agents on marine animals. Mar. Biol. 9, 183-201.
71. Toppari, J., Larsen, J. C., Christiansen, P., Giwercman, A., Grandjean, P., Guillette, L. J. Jr, Jégou, B., Jensen, T. K., Jouannet, P., Keiding, N., Leffers, H., McLachlan, J. A., Meyer, O., Müller, J., Rajpert-De Meyts, E., Scheike, T., Sharpe, R., Sumpter, J. & Skakkebæk, E. (1995). Male Reproductive Health and Environmental Chemicals with Estrogenic Effects. Miljøprojekt 290. Copenhagen, Danish Ministry of Energy and Environment, Copenhagen.
72. Truscott, B., Idler, D. R. & Fletcher, G. L. (1992). Alteration of reproductive steroids of male winter flounder (Pleuronectes americanus) chronically exposed to low levels of crude oil in sediments. Can. J. Fish Aquat. Sci. 49, 2190-2195.
73. Van Bohemen, Ch. G., Lambert, J. G. D. & Peute, J. (1981). Annual changes in plasma and liver in relation to vitellogenesis in the female rainbow trout, Salmo gairdneri. Gen. Comp. Endocrinol. 44, 94-107.
74. Wallace, R. A. (1985). Vitellogenesis and oocyte growth in nonmammalian vertebrates. In Developmental Biology (L. W. Browder, ed.), pp. 127-177. Plenum, New York.
75. Warhurst, A. M. (1995). An Environmental Assessment of Alkylphenol Ethoxylates and Alkylphenols. Friends of the Earth, Edinburgh. Bonnington Mill.
76. Weber, K. & Osborn, M. (1969). The reliability of molecular weight determinations by dodecyl-sulfate-polyacrylamide gel elecro-phoresis. J. Biol. Chem. 244, 4406-4412.
77. White, R., Jobling, S., Hoare, S. A., Sumpter, J. P. & Parker, M. G. (1994). Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 135, 175-182.
78. Zar, J. H. (1984). Biostatistical Analysis, Prentice-Hall, London.