The sodium/calcium exchanger family - SLC8

Pflugers Archiv European Journal of Physiology

Volumn 447, Issue 5, 2004, Pages 543-548

  Quednau, Beate D ^a   Nicoll, Debora A ^a   Philipson, Kenneth D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antiport; Calcium; Myocardium; Sodium; Sodium calcium exchange

Indexed keywords

CALCIUM ION; COTRANSPORTER; POTASSIUM ION; PROTEIN; PROTEIN NCX1; PROTEIN NCX2; PROTEIN NCX3; SLC24 PROTEIN; SLC8 PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; UNCLASSIFIED DRUG;

BRAIN TISSUE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; DRUG ACTIVITY; DRUG MECHANISM; GENE EXPRESSION REGULATION; HEART ARRHYTHMIA; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; MULTIGENE FAMILY; NONHUMAN; PATHOPHYSIOLOGY; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVIEW; SKELETAL MUSCLE; SODIUM CALCIUM EXCHANGE; SODIUM CELL LEVEL; SODIUM TRANSPORT; TISSUE DISTRIBUTION;

BIOLOGICAL TRANSPORT; CALCIUM; HUMANS; MULTIGENE FAMILY; MYOCARDIUM; SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 1242317702     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-003-1065-4     Document Type: Review

References (89)

1. 2+ exchanger. J Gen Physiol 109:717-729
2. Baker PF, Blaustein MP, Hodgkin AL, Steinhardt RA (1969) The influence of calcium on sodium efflux in squid axons. J Physiol (Lond) 200:431-458
3. Barnes KV, Cheng G, Dawson MM, Menick DR (1997) Cloning of cardiac, kidney, and brain promoters of the feline ncx1 gene. J Biol Chem 272:11510-11517
4. 2+ exchange in failing myocardium: friend or foe? Circ Res 87:529-531
5. Blaustein MP, Lederer WJ (1999) Sodium/calcium exchange: its physiological implications. Physiol Rev 79:763-854
6. 2+ exchanger peak near birth in developing rabbit and rat hearts. Circ Res 74:354-359
7. 2+ exchange protein in developing rabbit myocytes. Am J Physiol 268:C1126-C1132
8. 2+ exchanger gene. J Biol Chem 274:12819-12826
9. 2+ exchanger is essential for embryonic heart development in mice. Mol Cell 10:712-722
10. 2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice. Circ Res 83:1215-1223
11. Deval E, Levitsky DO, Constantin B, Raymond G, Cognard C (2000) Expression of the sodium/calcium exchanger in mammalian skeletal muscle cells in primary culture. Exp Cell Res 255:291-302
12. 2+ exchanger. J Biol Chem 273:778-783
13. 2+ exchanger. J Gen Physiol 114:701-711
14. 2+ exchanger expressed in Sf9 cells. Am J Physiol 45:C1184-C1192
15. 2+ exchanger in failing human myocardium. Circulation 94:992-1002
16. 2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study. J Cell Biol 117:337-345
17. 2+ exchanger in skeletal muscle. Am J Physiol 280:C146-C154
18. 2+ exchange in inside-out patches excised from guinea-pig ventricular myocytes. J Physiol (Lond) 523:339-351
19. Goldhaber JI (1999) Sodium-calcium exchange: the phantom menace. Circ Res 85:982-984
20. 2+ exchanger attenuates ischemic and hypoxic contractile dysfunction. Am J Physiol 279:H2846-H2854
21. 2+ exchanger protein levels and diastolic function of failing human myocardium. Circulation 99:641-648
22. 2 with the XIP region of the cardiac Na/Ca exchanger. Am J Physiol 278:C661-C666
23. 2. Science 273:956-959
24. Hilgemann DW, Collins A, Matsuoka S. (1992) Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP. J Gen Physiol 100:933-961
25. Hilgemann DW, Matsuoka S, Nagel GA, Collins A (1992) Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation. J Gen Physiol 100:905-932
26. 2+ exchange activity in canine pacing-induced heart failure. Circ Res 87:690-698
27. Houser SR, Piacentino V III, Weisser J (2000) Abnormalities of calcium cycling in the hypertrophied and failing heart. J Mol Cell Cardiol 32:1595-1607
28. 2+ exchanger. Mol Pharmacol 59:524-531
29. 2+ exchanger isoforms by divalent cations and isothiourea derivative. Am J Physiol 275:C423-C430
30. 2+ affinity. J Biol Chem 275:38571-38580
31. Jordan MC, Quednau BD, Roos KP, Ross RS, Philipson KD, Nicholas SB (2002) Cyclosporin A regulates sodium-calcium exchanger (NCX1) gene expression in vitro and cardiac hypertrophy in NCX1 transgenic mice. Ann NY Acad Sci 976:259-267
32. Juhaszova M, Church P, Blaustein MP, Stanley EF (2000) Location of calcium transporters at presynaptic terminals. Eur J Neurosci 12:839-846
33. Kaczorowski GJ, Slaughter RS, King VF, Garcia ML (1989) Inhibitors of sodium-calcium exchange: identification and development of probes of transport activity. Biochim Biophys Acta 988:287-302
34. 2+ exchanger in response to cardiac pressure overload. Am J Physiol 265:H1024-H1029
35. 2+ exchange system. Biochemistry 29:2437-2442
36. 2+ exchange in cardiac sarcolemmal vesicles. J Biol Chem 268:200-205
37. Kieval RS, Bloch GE, Lindenmayer A, Ambesi A, Lederer WJ (1992) Immunofluorescence localization of the Na-Ca exchanger in heart cells. Am J Physiol 263:C545-C550
38. Kofuji P, Lederer WJ, Schulze DH (1994) Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger. J Biol Chem 269:5145-5149
39. Koushik SV, Bundy J, Conway SJ (1999) Sodium-calcium exchanger is initially expressed in a heart-restricted pattern within the early mouse embryo. Mech Develop 88:119-122
40. Koushik SV, Wang J, Rogers R, Moskophidis D, Lambert NA, Creazzo TL, Conway SJ (2001) Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. FASEB J 15:1209-1211
41. 2+ exchanger isoforms. J Biol Chem 269:14849-14852
42. 2+ exchanger. Mol Cell Biochem 160/161:27-32
43. 2+ exchanger. J Biol Chem 269:22847-22852
44. 2+ exchanger isoforms in developing cerebellar neurons. J Biol Chem 275:20903-20910
45. 2+ exchanger binds to the cytoskeletal protein ankyrin. J Biol Chem 268:11489-11491
46. 2+ exchanger. J Biol Chem 269:17434-17439
47. 2+ exchanger. J Biol Chem 266:1014-1020
48. 2+ exchanger (NCX1, NCX2, NCX3). Am J Physiol 274:C415-C423
49. Luther PW, Yip RK, Bloch RJ, Ambesi A, Lindenmayer GE, Blaustein MP (1992) Presynaptic localization of sodium/ calcium exchangers in neuromuscular preparations. J Neurosci 12:4898-4904
50. Marlier LN, Zheng T, Tang J, Grayson DR (1993) Regional distribution in the rat central nervous system of a mRNA encoding a portion of the cardiac sodium/calcium exchanger isolated from cerebellar granule neurons. Mol Brain Res 20:21-39
51. 2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models. J Pharmacol Exp Ther 298:249-56
52. 2+ exchanger by the endogenous XIP region. J Gen Physiol 109:273-286
53. 2+-binding domain. J Gen Physiol 105:403-420
54. 2+ exchanger. Proc Natl Acad Sci USA 90:3870-3874
55. 2+ exchange assessed in transgenic mouse hearts. Am J Physiol 277:H2212-H2221
56. 2+ exchanger gene H1-promoter in a transgenic mouse model. Circ Res 90:158-164
57. Müller JG, Thompson JT, Edmonson AM, Rackley MS, Kasahara H, Izumo S, McQuinn TC, Menick DR, O'Brien TX (2002) Differential regulation of the cardiac sodium calcium exchanger promoter in adult and neonatal cardiomyocytes by Nkx2.5 and serum response factor. J Mol Cell Cardiol 34:807-821
58. 2+ exchanger and tissue-specific expression of isoforms. J Biochem 114:528-534
59. 2+ exchanger NCX1 is GATA factor dependent. Am J Physiol 277:H324-H330
60. 2+ exchanger gene. Am J Physiol 274:H217-H232
61. 2+ exchanger. J Biol Chem 271:13385-13391
62. 2+ exchanger. Science 250:562-565
63. 2+ exchanger. J Biol Chem 274:910-917
64. 2+ exchanger, NCX3. J Biol Chem 271:24914-24921
65. Philipson KD (1985) Sodium-calcium exchange in plasma membrane vesicles. Annu Rev Physiol 47:561-571
66. 2+ exchanger in the failing heart. Circ Res 87:641-643
67. 2+ exchanger in an arrhythmogenic rabbit model of heart failure. Circ Res 85:1009-1019
68. Qiu ZY, Chen J, Nicoll DA, Philipson KD (2001) A disulfide bond is required for functional assembly of NCX1 from complementary fragments. Biochem Biophys Res Commun 287:825-828
69. 2+ exchanger. J Biol Chem 276:194-199
70. 2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat. Am J Physiol 272:C1250-C1261
71. Reeves JP, Hale CC (1984) The stoichiometry of the cardiac sodium-calcium exchange system. J Biol Chem 259:7733-7739
72. 2+ exchanger in rabbit kidney. Am J Physiol 265:F327-F332
73. 2+ exchange inhibitors. Circ Res 91:90-92
74. 2+ exchanger is essential for the action of cardiac glycosides. Circ Res 90:305-308
75. Reuter H, Seitz N (1968) The dependence of calcium efflux from cardiac muscle on temperature and external ion composition. J Physiol (Lond) 195:45-70
76. 2+ exchanger. J Biol Chem 275:182-188
77. 2+ exchanger. Circ Res 87:581-587
78. Schwarz EM, Benzer S (1997) Calx, a Na-Ca exchanger gene of Drosophila melanogaster. Proc Natl Acad Sci USA 94:10249-10254
79. Scriven DRL, Dan P, Moore EDW (2000) Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes. Biophys J 79:2682-2691
80. + exchanger. EMBO J 18:3973-3980
81. 2+ exchanger expressed in CCL39 fibroblasts. Pflugers Arch 440:819-827
82. 2+ exchanger. J Gen Physiol 512.3:651-667
83. Thurneysen T, Nicoll DA, Philipson KD, Porzig H (2002) Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus cultures. Mol Brain Res 107:145-156
84. +-dependent alkaline earth metal uptake in cardiac sarcolemmal vesicles. Biochim Biophys Acta 817:327-332
85. 2+ exchanger gene leads to Cardiomyocyte apoptosis and defects in heartbeat. J Biol Chem 275:36991-36998
86. 2+ exchanger remodeling in pressure overload cardiac hypertrophy. J Biol Chem 276:17706-17711
87. 2+ exchange activity is localized in the T-tubules of rat ventricular myocytes. Circ Res 91:315-322
88. i transients in murine ventricular myocytes. Circ Res 82:657-665
89. 2+ exchanger isoforms in rat brain. Mol Brain Res 50:285-292