Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat

American Journal of Physiology - Cell Physiology

Volumn 272, Issue 4 41-4, 1997, Pages

  Quednau, Beate D ^a   Nicoll, Debora A ^a   Philipson, Kenneth D ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

developmental regulation; membrane protein; reverse transcriptase polymerase chain reaction

Indexed keywords

MEMBRANE PROTEIN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN; BRAIN CELL; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; DELETION MUTANT; EXON; GENE EXPRESSION; HEART; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SODIUM CALCIUM EXCHANGE; TISSUE SPECIFICITY;

ANIMALIA;

EID: 0030912068     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.272.4.c1250     Document Type: Article

References (18)

1. Aceto, J. F., M. Condrescu, C. Kroupis, H. Nelson, N. Nelson, D. Nicoll, K. D. Philipson, and J. P. Reeves. Cloning and expression of the bovine cardiac sodium-calcium exchanger. Arch. Biochem. Biophys. 298: 553-560, 1992.
2. Andreadis, A., M. E. Gallego, and B. Nadal-Ginard. Generation of protein isoform diversity by alternative splicing: mechanistic and biological implications. Annu. Rev. Cell Biol. 3: 207-242, 1987.
3. Ariano, M. A., R. B. Armstrong, and V. R. Edgerton. Hind-limb muscle fiber populations of five mammals. J. Histochem. Cytochem. 21: 51-55, 1973.
4. Blaustein, M. P., W. F. Goldman, G. Fontana, B. K. Krueger, E. M. Santiago, T. D. Steele, D. N. Weiss, and P. J. Yarowsky. Physiological roles of the sodium-calcium exchanger in nerve and muscle. Ann. NY Acad. Sci. 639: 254-274, 1991.
5. 2+ exchanger peak near birth in developing rabbit and rat hearts. Circ. Res. 74: 354-359, 1994.
6. Breitbart, R. E., and B. Nadal-Ginard. Developmentally induced, muscle-specific trans factors control the differential splicing of alternative and constitutive troponin T exons. Cell 49: 793-803, 1987.
7. Chelly, J., J.-P. Concordet, J.-C. Kaplan, and A. Kahn. Illegitimate transcription: transcription of any gene in any cell type. Proc. Natl. Acad. Sci. USA 86: 2617-2621, 1989.
8. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
9. Cole, R., and J. de Vellis. A Dissection and Tissue Culture Manual of the Nervous System, edited by A.-Shahar, J. de Vellis, A. Vernadakis, and B. Haber. New York: Liss, 1989, p. 121-133.
10. Condrescu, M., J. P. Gardner, G. Chernaya, J. F. Aceto, C. Kroupis, and J. P. Reeves. ATP-dependent regulation of sodium-calcium exchange in Chinese hamster ovary cells transfected with the bovine cardiac sodium-calcium exchanger. J. Biol. Chem. 270: 9137-9146, 1995.
11. Cooper, J. A., F. S. Esch, S. S. Taylor, and T. Hunter. Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro. J. Biol. Chem. 259: 7835-7841, 1984.
12. 1-subunit gene generates developmentally regulated isoforms in the rat heart. Proc. Natl. Acad. Sci. USA 89: 1497-1501, 1992.
13. DiPolo, R., and L. Beauge. Regulation of Na-Ca exchange. Ann. NY Acad. Sci. 639: 100-111, 1991.
14. 2+ exchanger gene and their functional expression in HeLa cells. FEBS Lett. 319: 105-109, 1993.
15. 2+ exchanger. J. Biol. Chem. 270: 6917-6924, 1995.
16. Goldman, W. F., P. J. Yarowsky, M. Juhaszova, B. K. Krueger, and M. P. Blaustein. Sodium/calcium exchange in rat cortical astrocytes. J. Neurosci. 14: 5834-5843, 1994.
17. Gordon, D., D. Merrick, V. Auld, R. Dunn, A. L. Goldin, N. Davidson, and W. A. Catterall. Tissue-specific expression of the R I and RII sodium channel subtypes. Proc. Natl. Acad. Sci. USA 84: 8682-8686, 1987.
18. 2+-transporting ATPase that is expressed predominantly in brain and skeletal muscle. J. Biol. Chem. 264: 18569-18576, 1989.