Thiopurine methyltransferase (TPMT) genotype distribution in azathioprine-tolerant and -intolerant patients with various disorders. The impact of TPMT genotyping in predicting toxicity

European Journal of Clinical Pharmacology

Volumn 59, Issue 11, 2004, Pages 797-801

  Reuther, Lene O ^a   Vainer, Ben ^b   Sonne, Jesper ^a   Larsen, Niels Erik ^b  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Azathioprine; Intolerance; Thiopurine methyltransferase

Indexed keywords

AZATHIOPRINE; DRUG METABOLITE; THIOPURINE METHYLTRANSFERASE;

ADULT; AGED; ARTICLE; BONE MARROW SUPPRESSION; BONE MARROW TOXICITY; CONTROLLED STUDY; DRUG METABOLISM; DRUG TOLERANCE; FEMALE; GENE MUTATION; GENETIC SCREENING; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TOXICITY;

6-MERCAPTOPURINE; ADJUVANTS, IMMUNOLOGIC; ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AZATHIOPRINE; FEMALE; GENOTYPE; GUANINE NUCLEOTIDES; HUMANS; MALE; METHYLTRANSFERASES; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; THIONUCLEOTIDES;

EID: 1242314812     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-003-0698-8     Document Type: Article

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