Emerging clinical applications of nucleic acids

Journal of Clinical Investigation

Volumn 106, Issue 8, 2000, Pages 921-922

  Sullenger, Bruce A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEASE; NUCLEIC ACID; RIBOZYME; RNA; TRANSCRIPTION FACTOR; TUMOR ANTIGEN; VIRUS PROTEIN; VIRUS VECTOR;

CANCER IMMUNOTHERAPY; CATALYSIS; GENE THERAPY; GENE TRANSFER; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOTHERAPY; PRIORITY JOURNAL; RNA CLEAVAGE; SHORT SURVEY; VACCINATION; VIRUS REPLICATION;

EID: 0033791887     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI11343     Document Type: Short Survey

References (11)

1. Overexertion of TAR sequences renders cells resistant to human immunodeficiency virus replication
2. Regulation of gene expression with double stranded phosphorothioate oligonucleotides
3. Systemic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
4. In vitro selection of RNA molecules that bind specific ligands
5. Dendritic cells and immune-based therapies
6. Self-splicing RNA: Autoexcision and autocyclizarion of the ribosomal RNA intervening sequence of Terrahymena
7. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
8. The Tetrahymena ribozyme acts like an RNA restriction endonuclease
9. Simple RNA enzymes with new and highly specific endoribonuclease activities
10. Ribozyme-mediated repair of defective mRNA by targeted trans-splicing
11. A DNA enzyme that cleaves RNA