메뉴 건너뛰기




Volumn 64, Issue 4, 2004, Pages 1266-1277

The Ews/Fli-1 Fusion Gene Switches the Differentiation Program of Neuroblastomas to Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumors

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; RNA BINDING PROTEIN EWS; TRANSCRIPTION FACTOR FLI 1; UNCLASSIFIED DRUG;

EID: 1242293672     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3274     Document Type: Article
Times cited : (72)

References (91)
  • 2
    • 0028997723 scopus 로고
    • Molecular basis for heterogeneity in human neuroblastomas
    • Brodeur, G. M. Molecular basis for heterogeneity in human neuroblastomas. Eur. J. Cancer, 31A: 505-510, 1995.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 505-510
    • Brodeur, G.M.1
  • 3
    • 0028855789 scopus 로고
    • A functional analysis of tumor suppressor activity for peripheral neuroepitheliomas by monochromosome transfer
    • Chen, P., Lin, H. H., and Weissman, B. E. A functional analysis of tumor suppressor activity for peripheral neuroepitheliomas by monochromosome transfer. Oncogene, 10: 577-586, 1995.
    • (1995) Oncogene , vol.10 , pp. 577-586
    • Chen, P.1    Lin, H.H.2    Weissman, B.E.3
  • 4
    • 0028232680 scopus 로고
    • Cytogenetics and experimental models of sarcomas
    • Fletcher, J. A. Cytogenetics and experimental models of sarcomas. Curr. Opin. Oncol., 6: 367-371, 1994.
    • (1994) Curr. Opin. Oncol. , vol.6 , pp. 367-371
    • Fletcher, J.A.1
  • 6
    • 0028225262 scopus 로고
    • Comparison of Ewing's sarcoma of bone and peripheral neuroepithelioma. An immunocytochemical and ultrastructural analysis of two primitive neuroectodermal neoplasms
    • Navarro, S., Cavazzana, A. O., Llombart-Bosch, A., and Triche, T. J. Comparison of Ewing's sarcoma of bone and peripheral neuroepithelioma. An immunocytochemical and ultrastructural analysis of two primitive neuroectodermal neoplasms. Arch. Pathol. Lab. Med., 118: 608-615, 1994.
    • (1994) Arch. Pathol. Lab. Med. , vol.118 , pp. 608-615
    • Navarro, S.1    Cavazzana, A.O.2    Llombart-Bosch, A.3    Triche, T.J.4
  • 7
    • 0031803306 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in Ewing's sarcomas and primitive neuroectodermal tumors revealed by reverse transcriptase-polymerase chain reaction of chromogranin mRNA
    • Pagani, A., Macri, L., Rosolen, A., Toffolatti, L., Stella, A., and Bussolati, G. Neuroendocrine differentiation in Ewing's sarcomas and primitive neuroectodermal tumors revealed by reverse transcriptase-polymerase chain reaction of chromogranin mRNA. Diagn. Mol. Pathol., 7: 36-43, 1998.
    • (1998) Diagn. Mol. Pathol. , vol.7 , pp. 36-43
    • Pagani, A.1    Macri, L.2    Rosolen, A.3    Toffolatti, L.4    Stella, A.5    Bussolati, G.6
  • 8
    • 0030862075 scopus 로고    scopus 로고
    • The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors
    • Grier, H. E. The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors. Pediatr. Clin. North Am., 44: 991-1004, 1997.
    • (1997) Pediatr. Clin. North Am. , vol.44 , pp. 991-1004
    • Grier, H.E.1
  • 9
    • 0001045505 scopus 로고    scopus 로고
    • Neuroblastoma and related tumors
    • D. M. Parham (ed.). Philadelphia: Lippincott-Raven
    • Kelly, D. R., and Joshi, V. V. Neuroblastoma and related tumors. In: D. M. Parham (ed.), Pediatric Neoplasia: Morphology and Biology, pp. 105-152. Philadelphia: Lippincott-Raven, 1996.
    • (1996) Pediatric Neoplasia: Morphology and Biology , pp. 105-152
    • Kelly, D.R.1    Joshi, V.V.2
  • 10
    • 0029061588 scopus 로고
    • Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome
    • Hedborg, F., Bjelfman, C., Sparen, P., Sandstedt, B., and Pahlman, S. Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome. Eur. J. Cancer, 31A: 435-443, 1995.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 435-443
    • Hedborg, F.1    Bjelfman, C.2    Sparen, P.3    Sandstedt, B.4    Pahlman, S.5
  • 11
    • 0032531963 scopus 로고    scopus 로고
    • Prognostic discrimination among neuroblastomas according to Ha-ras/trk A gene expression: A comparison of the profiles of neuroblastomas detected clinically and those detected through mass screening
    • Tanaka, T., Sugimoto, T., and Sawada, T. Prognostic discrimination among neuroblastomas according to Ha-ras/trk A gene expression: a comparison of the profiles of neuroblastomas detected clinically and those detected through mass screening. Cancer (Phila.), 83: 1626-1633, 1998.
    • (1998) Cancer (Phila.) , vol.83 , pp. 1626-1633
    • Tanaka, T.1    Sugimoto, T.2    Sawada, T.3
  • 12
    • 0032152769 scopus 로고    scopus 로고
    • Molecular basis of spontaneous regression of neuroblastoma: Role of neurotrophic signals and genetic abnormalities
    • Nakagawara, A. Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities. Hum. Cell, 11: 115-124, 1998.
    • (1998) Hum. Cell , vol.11 , pp. 115-124
    • Nakagawara, A.1
  • 13
    • 0025415390 scopus 로고
    • Human neuroblastoma tumor cell lines correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts
    • Cooper, M. J., Hutchins, G. M., Cohen, P. S., Helman, L. J., Mennie, R. J., and Israel, M. A. Human neuroblastoma tumor cell lines correspond to the arrested differentiation of chromaffin adrenal medullary neuroblasts. Cell Growth Differ., 1: 149-159, 1990.
    • (1990) Cell Growth Differ. , vol.1 , pp. 149-159
    • Cooper, M.J.1    Hutchins, G.M.2    Cohen, P.S.3    Helman, L.J.4    Mennie, R.J.5    Israel, M.A.6
  • 14
    • 0025339153 scopus 로고
    • β2-Microglobulin expression in human embryonal neuroblastoma reflects its developmental regulation
    • Cooper, M. J., Hutchins, G. M., Mennie, R. J., and Israel, M. A. β2-Microglobulin expression in human embryonal neuroblastoma reflects its developmental regulation. Cancer Res., 50: 3694-3700, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 3694-3700
    • Cooper, M.J.1    Hutchins, G.M.2    Mennie, R.J.3    Israel, M.A.4
  • 15
    • 0003625904 scopus 로고    scopus 로고
    • Ewing's sarcoma, peripheral neuroepithelioma, and related tumors
    • D. M. Parham (ed.). Philadelphia: Lippincott-Raven
    • Parham, D. M. Ewing's sarcoma, peripheral neuroepithelioma, and related tumors. In: D. M. Parham (ed.), Pediatric Neoplasia: Morphology and Biology, pp. 65-85. Philadelphia: Lippincott-Raven, 1996.
    • (1996) Pediatric Neoplasia: Morphology and Biology , pp. 65-85
    • Parham, D.M.1
  • 16
    • 0027230568 scopus 로고
    • Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FL11 for transformation
    • May, W. A., Gishizky, M. L., Lessnick, S. L., Lunsford, L. B., Lewis, B. C., Delattre, O., Zucman, J., Thomas, G., and Denny, C. T. Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FL11 for transformation. Proc. Natl. Acad. Sci. USA, 90: 5752-5756, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5752-5756
    • May, W.A.1    Gishizky, M.L.2    Lessnick, S.L.3    Lunsford, L.B.4    Lewis, B.C.5    Delattre, O.6    Zucman, J.7    Thomas, G.8    Denny, C.T.9
  • 17
    • 0027136095 scopus 로고
    • EWS/Fli-1 chimeric protein is a transcriptional activator
    • Ohno, T., Rao, V. N., and Reddy, E. S. EWS/Fli-1 chimeric protein is a transcriptional activator. Cancer Res., 53: 5859-5863, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5859-5863
    • Ohno, T.1    Rao, V.N.2    Reddy, E.S.3
  • 18
    • 0028821578 scopus 로고
    • Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene
    • Lessnick, S. L., Braun, B. S., Denny, C. T., and May, W. A. Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene. Oncogene, 10: 423-431, 1995.
    • (1995) Oncogene , vol.10 , pp. 423-431
    • Lessnick, S.L.1    Braun, B.S.2    Denny, C.T.3    May, W.A.4
  • 20
    • 0029873111 scopus 로고    scopus 로고
    • Gene rearrangements in Ewing's sarcoma
    • Denny, C. T. Gene rearrangements in Ewing's sarcoma. Cancer Investig., 14: 83-88, 1996.
    • (1996) Cancer Investig. , vol.14 , pp. 83-88
    • Denny, C.T.1
  • 21
    • 0028209984 scopus 로고
    • DNA-binding and transcriptional activation properties of the EWS-FL1-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma
    • Bailly, R. A., Bosselut, R., Zucman, J., Cormier, F., Delattre, O., Roussel, M., Thomas, G., and Ghysdael, J. DNA-binding and transcriptional activation properties of the EWS-FL1-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma. Mol. Cell. Biol., 14: 3230-3241, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3230-3241
    • Bailly, R.A.1    Bosselut, R.2    Zucman, J.3    Cormier, F.4    Delattre, O.5    Roussel, M.6    Thomas, G.7    Ghysdael, J.8
  • 23
    • 0023502622 scopus 로고
    • Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system
    • Thiele, C. J., McKeon, C., Triche, T. J., Ross, R. A., Reynolds, C. P., and Israel, M. A. Differential protooncogene expression characterizes histopathologically indistinguishable tumors of the peripheral nervous system. J. Clin. Investig., 80: 804-811, 1987.
    • (1987) J. Clin. Investig. , vol.80 , pp. 804-811
    • Thiele, C.J.1    McKeon, C.2    Triche, T.J.3    Ross, R.A.4    Reynolds, C.P.5    Israel, M.A.6
  • 24
    • 0035866778 scopus 로고    scopus 로고
    • The Ewing's sarcoma gene product functions as a transcriptional activator
    • Rossow, K. L., and Janknecht, R. The Ewing's sarcoma gene product functions as a transcriptional activator. Cancer Res., 61: 2690-2695, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 2690-2695
    • Rossow, K.L.1    Janknecht, R.2
  • 26
    • 0036739384 scopus 로고    scopus 로고
    • Affymetrix, Inc
    • Yap, G. Affymetrix, Inc. Pharmacogenomics, 3: 709-711, 2002.
    • (2002) Pharmacogenomics , vol.3 , pp. 709-711
    • Yap, G.1
  • 27
    • 17644440115 scopus 로고    scopus 로고
    • Microarray data analysis: A practical approach for selecting differentially expressed genes
    • PREPRINT0009
    • Mutch, D. M., Berger, A., Mansourian, R., Rytz, A., and Roberts, M. A. Microarray data analysis: a practical approach for selecting differentially expressed genes. Genome Biol., 2: PREPRINT0009, 2001.
    • (2001) Genome Biol. , vol.2
    • Mutch, D.M.1    Berger, A.2    Mansourian, R.3    Rytz, A.4    Roberts, M.A.5
  • 28
    • 0016937419 scopus 로고
    • Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol
    • Davidson, R. L., and Gerald, P. S. Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol. Somatic Cell Genet., 2: 165-176, 1976.
    • (1976) Somatic Cell Genet. , vol.2 , pp. 165-176
    • Davidson, R.L.1    Gerald, P.S.2
  • 29
    • 0023948089 scopus 로고
    • Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences
    • Kirschmeier, P. T., Housey, G. M., Johnson, M. D., Perkins, A. S., and Weinstein, I. B. Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences. DNA, 7: 219-225, 1988.
    • (1988) DNA , vol.7 , pp. 219-225
    • Kirschmeier, P.T.1    Housey, G.M.2    Johnson, M.D.3    Perkins, A.S.4    Weinstein, I.B.5
  • 30
    • 0023850352 scopus 로고
    • SR α promoter: An efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type I long terminal repeat
    • Takebe, Y., Seiki, M., Fujisawa, J., Hoy, P., Yokota, K., Arai, K., Yoshida, M., and Arai, N. SR α promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type I long terminal repeat. Mol. Cell. Biol., 8: 466-472, 1988.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 466-472
    • Takebe, Y.1    Seiki, M.2    Fujisawa, J.3    Hoy, P.4    Yokota, K.5    Arai, K.6    Yoshida, M.7    Arai, N.8
  • 33
    • 0000778479 scopus 로고
    • Extraction, purification, and analysis of messenger RNA from eukaryotic cells
    • C. Nolan (ed.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Sambrook, J., Fritsch, E. F., and Maniatis, T. Extraction, purification, and analysis of messenger RNA from eukaryotic cells, In: C. Nolan (ed.), Molecular Cloning: A Laboratory Manual, Vol. 1, pp. 7.3-7.84. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
    • (1989) Molecular Cloning: A Laboratory Manual , vol.1 , pp. 73-784
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 34
    • 0029961705 scopus 로고    scopus 로고
    • A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain
    • O'Bryan, J. P., Songyang, Z., Cantley, L., Der, C. J., and Pawson, T. A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain. Proc. Natl. Acad. Sci. USA, 93: 2729-2734, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2729-2734
    • O'Bryan, J.P.1    Songyang, Z.2    Cantley, L.3    Der, C.J.4    Pawson, T.5
  • 35
    • 0016293482 scopus 로고
    • HeLa-like marker chromosomes and type-A variant glucose-6-phosphate dehydrogenase isoenzyme in human cell cultures producing Mason-Pfizer monkey virus-like particles
    • Nelson-Rees, W. A., Zhdanov, V. M., Hawthorne, P. K., and Flandermeyer, R. R. HeLa-like marker chromosomes and type-A variant glucose-6-phosphate dehydrogenase isoenzyme in human cell cultures producing Mason-Pfizer monkey virus-like particles. J. Natl. Cancer Inst. (Bethesda), 53: 751-757, 1974.
    • (1974) J. Natl. Cancer Inst. (Bethesda) , vol.53 , pp. 751-757
    • Nelson-Rees, W.A.1    Zhdanov, V.M.2    Hawthorne, P.K.3    Flandermeyer, R.R.4
  • 36
    • 0028153706 scopus 로고
    • Functional evidence for a second tumor suppressor gene on human chromosome 17
    • Chen, P., Ellmore, N., and Weissman, B. E. Functional evidence for a second tumor suppressor gene on human chromosome 17. Mol. Cell. Biol., 14: 534-542, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 534-542
    • Chen, P.1    Ellmore, N.2    Weissman, B.E.3
  • 37
    • 0035328667 scopus 로고    scopus 로고
    • Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein
    • Chansky, H. A., Hu, M., Hickstein, D. D., and Yang, L. Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein. Cancer Res., 61: 3586-3590, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 3586-3590
    • Chansky, H.A.1    Hu, M.2    Hickstein, D.D.3    Yang, L.4
  • 39
    • 0034021393 scopus 로고    scopus 로고
    • Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis
    • Singh, N., Phillips, R. A., Iscove, N. N., and Egan, S. E. Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis. Exp. Hematol., 28: 527-534, 2000.
    • (2000) Exp. Hematol. , vol.28 , pp. 527-534
    • Singh, N.1    Phillips, R.A.2    Iscove, N.N.3    Egan, S.E.4
  • 40
    • 0033969388 scopus 로고    scopus 로고
    • Demarcation of early mammalian cortical development by differential expression of fringe genes
    • Ishii, Y., Nakamura, S., and Osumi, N. Demarcation of early mammalian cortical development by differential expression of fringe genes. Brain Res. Dev. Brain Res., 119: 307-320, 2000.
    • (2000) Brain Res. Dev. Brain Res. , vol.119 , pp. 307-320
    • Ishii, Y.1    Nakamura, S.2    Osumi, N.3
  • 41
    • 0031737362 scopus 로고    scopus 로고
    • Differential expression pattern of the three Fringe genes is associated with epidermal differentiation
    • Thelu, J., Viallet, J. P., and Dhouailly, D. Differential expression pattern of the three Fringe genes is associated with epidermal differentiation. J. Investig. Dermatol., 111: 903-906, 1998.
    • (1998) J. Investig. Dermatol. , vol.111 , pp. 903-906
    • Thelu, J.1    Viallet, J.P.2    Dhouailly, D.3
  • 42
    • 0032848660 scopus 로고    scopus 로고
    • Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLII oncoprotein
    • Hahm, K. B., Cho, K., Lee, C., Im, Y. H., Chang, J., Choi, S. G., Sorensen, P. H., Thiele, C. J., and Kim, S. J. Repression of the gene encoding the TGF-β type II receptor is a major target of the EWS-FLII oncoprotein. Nat. Genet., 23: 222-227, 1999.
    • (1999) Nat. Genet. , vol.23 , pp. 222-227
    • Hahm, K.B.1    Cho, K.2    Lee, C.3    Im, Y.H.4    Chang, J.5    Choi, S.G.6    Sorensen, P.H.7    Thiele, C.J.8    Kim, S.J.9
  • 43
    • 0036888335 scopus 로고    scopus 로고
    • Integration of the TGF-β pathway into the cellular signalling network
    • Lutz, M., and Knaus, P. Integration of the TGF-β pathway into the cellular signalling network. Cell Signalling, 14: 977-988, 2002.
    • (2002) Cell Signalling , vol.14 , pp. 977-988
    • Lutz, M.1    Knaus, P.2
  • 44
    • 0029809187 scopus 로고    scopus 로고
    • N-Shc: A neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway
    • Nakamura, T., Sanokawa, R., Sasaki, Y., Ayusawa, D., Oishi, M., and Mori, N. N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway. Oncogene, 13: 1111-1121, 1996.
    • (1996) Oncogene , vol.13 , pp. 1111-1121
    • Nakamura, T.1    Sanokawa, R.2    Sasaki, Y.3    Ayusawa, D.4    Oishi, M.5    Mori, N.6
  • 45
    • 0028293929 scopus 로고
    • Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC γ
    • Obermeier, A., Bradshaw, R. A., Seedorf, K., Choidas, A., Schlessinger, J., and Ullrich, A. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC γ. EMBO J., 13: 1585-1590, 1994.
    • (1994) EMBO J. , vol.13 , pp. 1585-1590
    • Obermeier, A.1    Bradshaw, R.A.2    Seedorf, K.3    Choidas, A.4    Schlessinger, J.5    Ullrich, A.6
  • 46
    • 0028199799 scopus 로고
    • Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ I to mediate NGF responses
    • Stephens, R. M., Loeb, D. M., Copeland, T. D., Pawson, T., Greene, L. A., and Kaplan, D. R. Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ I to mediate NGF responses. Neuron, 12: 691-705, 1994.
    • (1994) Neuron , vol.12 , pp. 691-705
    • Stephens, R.M.1    Loeb, D.M.2    Copeland, T.D.3    Pawson, T.4    Greene, L.A.5    Kaplan, D.R.6
  • 47
    • 0032213730 scopus 로고    scopus 로고
    • Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain
    • Cattaneo, E., and Pelicci, P. G. Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain. Trends Neurosci., 21: 476-481, 1998.
    • (1998) Trends Neurosci. , vol.21 , pp. 476-481
    • Cattaneo, E.1    Pelicci, P.G.2
  • 48
    • 0030860786 scopus 로고    scopus 로고
    • Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain
    • Conti, L., De Fraja, C., Gulisano, M., Migliaccio, E., Govoni, S., and Cattaneo, E. Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain. Proc. Natl. Acad. Sci. USA, 94: 8185-8190, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8185-8190
    • Conti, L.1    De Fraja, C.2    Gulisano, M.3    Migliaccio, E.4    Govoni, S.5    Cattaneo, E.6
  • 49
    • 0031842341 scopus 로고    scopus 로고
    • Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
    • Ganju, P., O'Bryan, J. P., Der, C., Winter, J., and James, I. F. Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells. Eur. J. Neurosci., 10: 1995-2008, 1998.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1995-2008
    • Ganju, P.1    O'Bryan, J.P.2    Der, C.3    Winter, J.4    James, I.F.5
  • 50
    • 0034520582 scopus 로고    scopus 로고
    • The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons
    • Sakai, R., Henderson, J. T., O'Bryan, J. P., Elia, A. J., Saxton, T. M., and Pawson, T. The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons. Neuron, 28: 819-833, 2000.
    • (2000) Neuron , vol.28 , pp. 819-833
    • Sakai, R.1    Henderson, J.T.2    O'Bryan, J.P.3    Elia, A.J.4    Saxton, T.M.5    Pawson, T.6
  • 51
    • 0029556562 scopus 로고
    • Structural and functional properties of the TRK family of neurotrophin receptors
    • Barbacid, M. Structural and functional properties of the TRK family of neurotrophin receptors. Ann. N. Y. Acad. Sci., 766: 442-458, 1995.
    • (1995) Ann. N. Y. Acad. Sci. , vol.766 , pp. 442-458
    • Barbacid, M.1
  • 52
    • 0025281397 scopus 로고
    • The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain
    • Klein, R., Conway, D., Parada, L. F., and Barbacid, M. The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain. Cell, 61: 647-656, 1990.
    • (1990) Cell , vol.61 , pp. 647-656
    • Klein, R.1    Conway, D.2    Parada, L.F.3    Barbacid, M.4
  • 55
    • 0036042919 scopus 로고    scopus 로고
    • Software and methods for oligonucleotide and cDNA array data analysis
    • SOFTWARE0001
    • Zapala, M. A., Lockhart, D. J., Pankratz, D. G., Garcia, A. J., and Barlow, C. Software and methods for oligonucleotide and cDNA array data analysis. Genome Biol., 3: 6 SOFTWARE0001, 2002.
    • (2002) Genome Biol. , vol.3 , pp. 6
    • Zapala, M.A.1    Lockhart, D.J.2    Pankratz, D.G.3    Garcia, A.J.4    Barlow, C.5
  • 56
    • 0015170823 scopus 로고
    • Expression of differentiated functions in hepatoma cell hybrids: Reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes
    • Weiss, M. C., and Chaplain, M. Expression of differentiated functions in hepatoma cell hybrids: reappearance of tyrosine aminotransferase inducibility after the loss of chromosomes. Proc. Natl. Acad. Sci. USA, 68: 3026-3030, 1971.
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 3026-3030
    • Weiss, M.C.1    Chaplain, M.2
  • 57
    • 0016586393 scopus 로고
    • Expression of differentiated functions in hepatoma cell hybrids: IX extinction and reexpression of liver-specific enzymes in rat hepatoma-Chinese hamster fibroblast hybrids
    • Weiss, M. C., Sparkes, R. S., and Bertolotti, R. Expression of differentiated functions in hepatoma cell hybrids: IX extinction and reexpression of liver-specific enzymes in rat hepatoma-Chinese hamster fibroblast hybrids. Somatic Cell Genet., 1: 27-40, 1975.
    • (1975) Somatic Cell Genet. , vol.1 , pp. 27-40
    • Weiss, M.C.1    Sparkes, R.S.2    Bertolotti, R.3
  • 58
    • 0021133977 scopus 로고
    • A genetic analysis of extinction: Trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells
    • Killary, A. M., and Fournier, R. E. A genetic analysis of extinction: trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells. Cell, 38: 523-534, 1984.
    • (1984) Cell , vol.38 , pp. 523-534
    • Killary, A.M.1    Fournier, R.E.2
  • 59
    • 0014976174 scopus 로고
    • Expression of differentiated functions in hepatoma cell hybrids. I. Tyrosine aminotransferase in hepatoma-fibroblast hybrids
    • Schneider, J. A., and Weiss, M. C. Expression of differentiated functions in hepatoma cell hybrids. I. Tyrosine aminotransferase in hepatoma-fibroblast hybrids. Proc. Natl. Acad. Sci. USA, 68: 127-131, 1971.
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 127-131
    • Schneider, J.A.1    Weiss, M.C.2
  • 60
    • 0033945495 scopus 로고    scopus 로고
    • Analysis of cranial neural crest migratory pathways in axolotl using cell markers and transplantation
    • Epperlein, H., Meulemans, D., Bronner-Fraser, M., Steinbeisser, H., and Selleck, M. A. Analysis of cranial neural crest migratory pathways in axolotl using cell markers and transplantation. Development (Camb.), 127: 2751-2761, 2000.
    • (2000) Development (Camb.) , vol.127 , pp. 2751-2761
    • Epperlein, H.1    Meulemans, D.2    Bronner-Fraser, M.3    Steinbeisser, H.4    Selleck, M.A.5
  • 61
    • 0029035156 scopus 로고
    • Retinoic acid and cAMP differentially regulate human chromogranin A promoter activity during differentiation of neuroblastoma cells
    • Gaetano, C., Manni, I., Bossi, G., Piaggio, G., Soddu, S., Farina, A., Helman, L. J., and Sacchi, A. Retinoic acid and cAMP differentially regulate human chromogranin A promoter activity during differentiation of neuroblastoma cells. Eur. J. Cancer, 31A: 447-452, 1995.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 447-452
    • Gaetano, C.1    Manni, I.2    Bossi, G.3    Piaggio, G.4    Soddu, S.5    Farina, A.6    Helman, L.J.7    Sacchi, A.8
  • 62
    • 0030931381 scopus 로고    scopus 로고
    • Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter
    • Jensen, D. E., Black, A. R., Swick, A. G., and Azizkhan, J. C. Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter. J. Cell. Biochem., 67: 24-31, 1997.
    • (1997) J. Cell. Biochem. , vol.67 , pp. 24-31
    • Jensen, D.E.1    Black, A.R.2    Swick, A.G.3    Azizkhan, J.C.4
  • 64
    • 0027154784 scopus 로고
    • Multiple DNA-protein interactions at the CpG island of the human pseudoautosomal gene MIC2
    • Braghetti, A., Piazzi, G., Lanfranco, L., and Mondello, C. Multiple DNA-protein interactions at the CpG island of the human pseudoautosomal gene MIC2. Somatic Cell Mol. Genet., 19: 51-63, 1993.
    • (1993) Somatic Cell Mol. Genet. , vol.19 , pp. 51-63
    • Braghetti, A.1    Piazzi, G.2    Lanfranco, L.3    Mondello, C.4
  • 65
    • 0026544309 scopus 로고
    • Ewing's tumor X mouse hybrids expressing the MIC2 antigen: Analyses using fluorescence CDD-banding and non-isotopic ISH
    • Dworzak, M., Stock, C., Strehl, S., Gadner, H., and Ambros, P. F. Ewing's tumor X mouse hybrids expressing the MIC2 antigen: analyses using fluorescence CDD-banding and non-isotopic ISH. Hum. Genet., 88: 273-278, 1992.
    • (1992) Hum. Genet. , vol.88 , pp. 273-278
    • Dworzak, M.1    Stock, C.2    Strehl, S.3    Gadner, H.4    Ambros, P.F.5
  • 66
    • 0034968428 scopus 로고    scopus 로고
    • Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression
    • Dauphinot, L., De Oliveira, C., Melot, T., Sevenet, N., Thomas, V., Weissman, B. E., and Delattre, O. Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression. Oncogene, 20: 3258-3265, 2001.
    • (2001) Oncogene , vol.20 , pp. 3258-3265
    • Dauphinot, L.1    De Oliveira, C.2    Melot, T.3    Sevenet, N.4    Thomas, V.5    Weissman, B.E.6    Delattre, O.7
  • 67
    • 0029981560 scopus 로고    scopus 로고
    • Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction
    • Lin, S. Y., Black, A. R., Kostic, D., Pajovic, S., Hoover, C. N., and Azizkhan, J. C. Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol. Cell. Biol., 16: 1668-1675, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1668-1675
    • Lin, S.Y.1    Black, A.R.2    Kostic, D.3    Pajovic, S.4    Hoover, C.N.5    Azizkhan, J.C.6
  • 68
    • 0030028934 scopus 로고    scopus 로고
    • Transcriptional regulation of the dihydrofolate reductase gene
    • Slansky, J. E., and Farnham, P. J. Transcriptional regulation of the dihydrofolate reductase gene. Bioessays, 18: 55-62, 1996.
    • (1996) Bioessays , vol.18 , pp. 55-62
    • Slansky, J.E.1    Farnham, P.J.2
  • 69
    • 0028791358 scopus 로고
    • Neural and mesenchymal differentiations in Ewing's sarcoma cell lines. Morphological, immunophenotypic, molecular biological and cytogenetic evidence
    • Pagani, A., Fischer-Colbrie, R., Eder, U., Pellin, A., Llombart-Bosch, A., and Bussolati, G. Neural and mesenchymal differentiations in Ewing's sarcoma cell lines. Morphological, immunophenotypic, molecular biological and cytogenetic evidence. Int. J. Cancer, 63: 738-743, 1995.
    • (1995) Int. J. Cancer , vol.63 , pp. 738-743
    • Pagani, A.1    Fischer-Colbrie, R.2    Eder, U.3    Pellin, A.4    Llombart-Bosch, A.5    Bussolati, G.6
  • 70
    • 0034684616 scopus 로고    scopus 로고
    • Expression and function of Ets transcription factors in mammalian development: A regulatory network
    • Maroulakou, I. G., and Bowe, D. B. Expression and function of Ets transcription factors in mammalian development: a regulatory network. Oncogene, 19: 6432-6442, 2000.
    • (2000) Oncogene , vol.19 , pp. 6432-6442
    • Maroulakou, I.G.1    Bowe, D.B.2
  • 71
    • 0033602173 scopus 로고    scopus 로고
    • FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts
    • Pereira, R., Quang, C. T., Lesault, I., Dolznig, H., Beug, H., and Ghysdael, J. FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts. Oncogene, 18: 1597-1608, 1999.
    • (1999) Oncogene , vol.18 , pp. 1597-1608
    • Pereira, R.1    Quang, C.T.2    Lesault, I.3    Dolznig, H.4    Beug, H.5    Ghysdael, J.6
  • 73
    • 0026166356 scopus 로고
    • Dissociation of suppression of tumorigenicity and differentiation in vitro effected by transfer of single human chromosomes into human neuroblastoma cells
    • Bader, S. A., Fasching, C., Brodeur, G. M., and Stanbridge, E. J. Dissociation of suppression of tumorigenicity and differentiation in vitro effected by transfer of single human chromosomes into human neuroblastoma cells. Cell Growth Differ., 2: 245-255, 1991.
    • (1991) Cell Growth Differ. , vol.2 , pp. 245-255
    • Bader, S.A.1    Fasching, C.2    Brodeur, G.M.3    Stanbridge, E.J.4
  • 74
    • 0033034390 scopus 로고    scopus 로고
    • Molecular biology of neuroblastoma
    • Maris, J. M., and Matthay, K. K. Molecular biology of neuroblastoma. J. Clin. Oncol., 17: 2264-2279, 1999.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2264-2279
    • Maris, J.M.1    Matthay, K.K.2
  • 75
    • 0028923604 scopus 로고
    • Constitutional translocation t(1; 17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NFI/SCYA7 on chromosome 17 as breakpoint flanking single copy markers
    • Laureys, G., Speleman, F., Versteeg, R., van der Drift, P., Chan, A., Leroy, J., Francke, U., Opdenakker, G., and Van Roy, N. Constitutional translocation t(1; 17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NFI/SCYA7 on chromosome 17 as breakpoint flanking single copy markers. Oncogene, 10: 1087-1093, 1995.
    • (1995) Oncogene , vol.10 , pp. 1087-1093
    • Laureys, G.1    Speleman, F.2    Versteeg, R.3    Van Der Drift, P.4    Chan, A.5    Leroy, J.6    Francke, U.7    Opdenakker, G.8    Van Roy, N.9
  • 77
    • 0037742405 scopus 로고    scopus 로고
    • Ewing tumor fusion proteins block the differentiation of pluripotent marrow stromal cells
    • Torchia, E. C., Jaishankar, S., and Baker, S. J. Ewing tumor fusion proteins block the differentiation of pluripotent marrow stromal cells. Cancer Res., 63: 3464-3468, 2003.
    • (2003) Cancer Res. , vol.63 , pp. 3464-3468
    • Torchia, E.C.1    Jaishankar, S.2    Baker, S.J.3
  • 78
    • 0036965929 scopus 로고    scopus 로고
    • TGF-β the Smad signal transduction pathway
    • Mehra, A., and Wrana, J. L. TGF-β and the Smad signal transduction pathway. Biochem. Cell Biol., 80: 605-622, 2002.
    • (2002) Biochem. Cell Biol. , vol.80 , pp. 605-622
    • Mehra, A.1    Wrana, J.L.2
  • 80
    • 0031895560 scopus 로고    scopus 로고
    • Cyclin D1 and human neoplasia
    • Donnellan, R., and Chetty, R. Cyclin D1 and human neoplasia. Mol. Pathol., 51: 1-7, 1998.
    • (1998) Mol. Pathol. , vol.51 , pp. 1-7
    • Donnellan, R.1    Chetty, R.2
  • 81
    • 0037376168 scopus 로고    scopus 로고
    • Cyclin DI serves as a cell cycle regulatory switch in actively proliferating cells
    • Stacey, D. W. Cyclin DI serves as a cell cycle regulatory switch in actively proliferating cells. Curr. Opin. Cell Biol., 15: 158-163, 2003.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 158-163
    • Stacey, D.W.1
  • 85
    • 0037427070 scopus 로고    scopus 로고
    • Upregulation of Id2, an oncogenic helix-loop-helix protein, is mediated by the chimeric EWS/ets protein in Ewing sarcoma
    • Fukuma, M., Okita, H., Hata, J., and Umezawa, A. Upregulation of Id2, an oncogenic helix-loop-helix protein, is mediated by the chimeric EWS/ets protein in Ewing sarcoma. Oncogene, 22: 1-9, 2003.
    • (2003) Oncogene , vol.22 , pp. 1-9
    • Fukuma, M.1    Okita, H.2    Hata, J.3    Umezawa, A.4
  • 87
    • 0035193372 scopus 로고    scopus 로고
    • Negative regulators of cyclin-dependent kinases and their roles in cancers
    • Lee, M. H., and Yang, H. Y. Negative regulators of cyclin-dependent kinases and their roles in cancers. Cell Mol. Life Sci., 58: 1907-1922, 2001.
    • (2001) Cell Mol. Life Sci. , vol.58 , pp. 1907-1922
    • Lee, M.H.1    Yang, H.Y.2
  • 88
    • 0020044112 scopus 로고
    • Definition of a Thy-1 determinant on human neuroblastoma, glioma, sarcoma, and teratoma cells with a monoclonal antibody
    • Seeger, R. C., Danon, Y. L., Rayner, S. A., and Hoover, F. Definition of a Thy-1 determinant on human neuroblastoma, glioma, sarcoma, and teratoma cells with a monoclonal antibody. J. Immunol., 128: 983-989, 1982.
    • (1982) J. Immunol. , vol.128 , pp. 983-989
    • Seeger, R.C.1    Danon, Y.L.2    Rayner, S.A.3    Hoover, F.4
  • 89
    • 0017698493 scopus 로고
    • Chromosomal aberrations in human neuroblastomas
    • Brodeur, G. M., Sekhon, G., and Goldstein, M. N. Chromosomal aberrations in human neuroblastomas. Cancer (Phila.), 40: 2256-2263, 1977.
    • (1977) Cancer (Phila.) , vol.40 , pp. 2256-2263
    • Brodeur, G.M.1    Sekhon, G.2    Goldstein, M.N.3
  • 91
    • 0015817744 scopus 로고
    • Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture
    • Biedler, J. L., Helson, L., and Spengler, B. A. Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res., 33: 2643-2652, 1973.
    • (1973) Cancer Res. , vol.33 , pp. 2643-2652
    • Biedler, J.L.1    Helson, L.2    Spengler, B.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.