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Volumn 63, Issue 13, 2003, Pages 3464-3468

Ewing tumor fusion proteins block the differentiation of pluripotent marrow stromal cells

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN;

EID: 0037742405     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (105)

References (31)
  • 2
    • 0035839938 scopus 로고    scopus 로고
    • Biology of EWS/ETS fusions in Ewing's family tumors
    • Arvand, A., and Denny, C. T. Biology of EWS/ETS fusions in Ewing's family tumors. Oncogene, 20: 5747-5754, 2001.
    • (2001) Oncogene , vol.20 , pp. 5747-5754
    • Arvand, A.1    Denny, C.T.2
  • 3
    • 0034684619 scopus 로고    scopus 로고
    • Ets target genes: Past, present and future
    • Sementchenko, V. I., and Watson, D. K. Ets target genes: past, present and future. Oncogene, 19: 6533-6548, 2000.
    • (2000) Oncogene , vol.19 , pp. 6533-6548
    • Sementchenko, V.I.1    Watson, D.K.2
  • 4
    • 0035933847 scopus 로고    scopus 로고
    • EWS/FLI alters 5′-splice site selection
    • Knoop, L. L., and Baker, S. J. EWS/FLI alters 5′-splice site selection. J. Biol. Chem., 276: 22317-22322, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22317-22322
    • Knoop, L.L.1    Baker, S.J.2
  • 5
    • 0023215290 scopus 로고
    • Experimental evidence for a neural origin of Ewing's sarcoma of bone
    • Cavazzana, A. O., Miser, J. S., Jefferson, J., and Triche, T. J. Experimental evidence for a neural origin of Ewing's sarcoma of bone. Am. J. Pathol., 127: 507-518, 1987.
    • (1987) Am. J. Pathol. , vol.127 , pp. 507-518
    • Cavazzana, A.O.1    Miser, J.S.2    Jefferson, J.3    Triche, T.J.4
  • 6
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop, D. J. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science (Wash. DC), 276: 71-74, 1997.
    • (1997) Science (Wash. DC) , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 7
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey, E., Chandross, K. J., Harta, G., Maki, R. A., and McKercher, S. R. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science (Wash. DC), 290: 1779-1782, 2000.
    • (2000) Science (Wash. DC) , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3    Maki, R.A.4    McKercher, S.R.5
  • 8
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • Brazelton, T. R., Rossi, F. M., Keshet, G. I., and Blau, H. M. From marrow to brain: expression of neuronal phenotypes in adult mice. Science (Wash. DC), 290: 1775-1779, 2000.
    • (2000) Science (Wash. DC) , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.2    Keshet, G.I.3    Blau, H.M.4
  • 10
    • 0033559266 scopus 로고    scopus 로고
    • Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: Variations in yield, growth, and differentiation
    • Phinney, D. G., Kopen, G., Isaacson, R. L., and Prockop, D. J. Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation. J. Cell. Biochem., 72: 570-585, 1999.
    • (1999) J. Cell. Biochem. , vol.72 , pp. 570-585
    • Phinney, D.G.1    Kopen, G.2    Isaacson, R.L.3    Prockop, D.J.4
  • 11
    • 0027362619 scopus 로고
    • The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1
    • May, W. A., Lessnick, S. L., Braun, B. S., Klemsz, M., Lewis, B. C., Lunsford, L. B., Hromas, R., and Denny, C. T. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol. Cell. Biol., 13: 7393-7398, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7393-7398
    • May, W.A.1    Lessnick, S.L.2    Braun, B.S.3    Klemsz, M.4    Lewis, B.C.5    Lunsford, L.B.6    Hromas, R.7    Denny, C.T.8
  • 13
    • 0034282763 scopus 로고    scopus 로고
    • Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases
    • Groth, A., Weber, J. D., Willumsen, B. M., Sherr, C. J., and Roussel, M. F. Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases. J. Biol. Chem., 275: 27473-27480, 2000.
    • (2000) J. Biol. Chem. , vol.275 , pp. 27473-27480
    • Groth, A.1    Weber, J.D.2    Willumsen, B.M.3    Sherr, C.J.4    Roussel, M.F.5
  • 14
    • 0033619101 scopus 로고    scopus 로고
    • Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity
    • Jaishankar, S., Zhang, J., Roussel, M. F., and Baker, S. J. Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity. Oncogene, 18: 5592-5597, 1999.
    • (1999) Oncogene , vol.18 , pp. 5592-5597
    • Jaishankar, S.1    Zhang, J.2    Roussel, M.F.3    Baker, S.J.4
  • 15
    • 0035361602 scopus 로고    scopus 로고
    • PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells
    • Zhu, X., Kwon, C. H., Schlosshauer, P. W., Ellenson, L. H., and Baker, S. J. PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells. Cancer Res., 61: 4569-4575, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 4569-4575
    • Zhu, X.1    Kwon, C.H.2    Schlosshauer, P.W.3    Ellenson, L.H.4    Baker, S.J.5
  • 16
    • 0034980666 scopus 로고    scopus 로고
    • Induction of senescence by oncogenic Ras
    • Palmero, I., and Serrano, M. Induction of senescence by oncogenic Ras. Methods Enzymol., 333: 247-256, 2001.
    • (2001) Methods Enzymol. , vol.333 , pp. 247-256
    • Palmero, I.1    Serrano, M.2
  • 17
    • 0030783770 scopus 로고    scopus 로고
    • Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors
    • Kovar, H., Jug, G., Aryee, D. N., Zoubek, A., Ambros, P., Gruber, B., Windhager, R., and Gadner, H. Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors. Oncogene, 15: 2225-2232, 1997.
    • (1997) Oncogene , vol.15 , pp. 2225-2232
    • Kovar, H.1    Jug, G.2    Aryee, D.N.3    Zoubek, A.4    Ambros, P.5    Gruber, B.6    Windhager, R.7    Gadner, H.8
  • 19
    • 0034661248 scopus 로고    scopus 로고
    • Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma
    • Tsuchiya, T., Sekine, K., Hinohara, S., Namiki, T., Nobori, T., and Kaneko, Y. Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma. Cancer Genet. Cytogenet., 120: 91-98, 2000.
    • (2000) Cancer Genet. Cytogenet. , vol.120 , pp. 91-98
    • Tsuchiya, T.1    Sekine, K.2    Hinohara, S.3    Namiki, T.4    Nobori, T.5    Kaneko, Y.6
  • 21
    • 0035845859 scopus 로고    scopus 로고
    • Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation
    • Deneen, B., and Denny, C. T. Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation. Oncogene, 20: 6731-6741, 2001.
    • (2001) Oncogene , vol.20 , pp. 6731-6741
    • Deneen, B.1    Denny, C.T.2
  • 22
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury, D., Schwarz, E. J., Prockop, D. J., and Black, I. B. Adult rat and human bone marrow stromal cells differentiate into neurons. J. Neurosci. Res., 61: 364-370, 2000.
    • (2000) J. Neurosci. Res. , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 23
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen, G. C., Prockop, D. J., and Phinney, D. G. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl. Acad. Sci. USA, 96: 10711-10716, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 24
    • 0037218795 scopus 로고    scopus 로고
    • Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma
    • Eliazer, S., Spencer, J., Ye, D., Olson, E., and Ilaria, R. L., Jr. Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma. Mol. Cell. Biol., 23: 482-492, 2003.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 482-492
    • Eliazer, S.1    Spencer, J.2    Ye, D.3    Olson, E.4    Ilaria R.L., Jr.5
  • 25
    • 0023354739 scopus 로고
    • The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation
    • Olson, E. N., Spizz, G., and Tainsky, M. A. The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation. Mol. Cell. Biol., 7: 2104-2111, 1987.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2104-2111
    • Olson, E.N.1    Spizz, G.2    Tainsky, M.A.3
  • 26
    • 0024370528 scopus 로고
    • Transformation by activated ras or fos prevents myogenesis by inhibiting expression of MyoD1
    • Lassar, A. B., Thayer, M. J., Overell, R. W., and Weintraub, H. Transformation by activated ras or fos prevents myogenesis by inhibiting expression of MyoD1. Cell, 58: 659-667, 1989.
    • (1989) Cell , vol.58 , pp. 659-667
    • Lassar, A.B.1    Thayer, M.J.2    Overell, R.W.3    Weintraub, H.4
  • 27
    • 0030658039 scopus 로고    scopus 로고
    • Oncogenic transcription factors in the human acute leukemias
    • Look, A. T. Oncogenic transcription factors in the human acute leukemias. Science (Wash. DC), 278: 1059-1064, 1997.
    • (1997) Science (Wash. DC) , vol.278 , pp. 1059-1064
    • Look, A.T.1
  • 28
    • 0037315894 scopus 로고    scopus 로고
    • Disruption of differentiation in human cancer: AML shows the way
    • Tenen, D. G. Disruption of differentiation in human cancer: AML shows the way. Nat. Rev. Cancer, 3: 89-101, 2003.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 89-101
    • Tenen, D.G.1
  • 29
    • 0034684609 scopus 로고    scopus 로고
    • The role of Fli-1 in normal cell function and malignant transformation
    • Truong, A. H., and Ben-David, Y. The role of Fli-1 in normal cell function and malignant transformation. Oncogene, 19: 6482-6489, 2000.
    • (2000) Oncogene , vol.19 , pp. 6482-6489
    • Truong, A.H.1    Ben-David, Y.2
  • 30
    • 0035834675 scopus 로고    scopus 로고
    • DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis
    • Welford, S. M., Hebert, S. P., Deneen, B., Arvand, A., and Denny, C. T. DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis. J. Biol. Chem., 276: 41977-41984, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41977-41984
    • Welford, S.M.1    Hebert, S.P.2    Deneen, B.3    Arvand, A.4    Denny, C.T.5
  • 31
    • 0035393826 scopus 로고    scopus 로고
    • The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1
    • Arvand, A., Welford, S. M., Teitell, M. A., and Denny, C. T. The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1. Cancer Res., 61: 5311-5317, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 5311-5317
    • Arvand, A.1    Welford, S.M.2    Teitell, M.A.3    Denny, C.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.