Synthesis of New Pyrrolo[2, 3-b]pyridines as a Potent Inhibitor of Tumour Necrosis Factor Alpha

Archiv der Pharmazie

Volumn 337, Issue 1, 2004, Pages 15-19

  Mohammed, Khalid ^a,b   Hilmy, Hassan ^a,b  

^a MENOUFIA UNIVERSITY   (Egypt)

^b NONE   (Egypt)

Author keywords

Pyrrolo 2,3 b pyridines; TNF inhibitor

Indexed keywords

2 AMINO 3 CYANOPYRROLE DERIVATIVE; 2 AMINO 5 (4 BROMOPHENYL) 1 PHENYL 1H PYRROLE 3 CARBONITRILE; 2 AMINO 5 (4 FLUOROPHENYL) 1 PHENYL 1H PYRROLE 3 CARBONITRILE; 2 AMINO 5 (4 METHOXYPHENYL) 1 PHENYL 1H PYRROLE 3 CARBONITRILE; 3 (3 CYANO 1,5 DIPHENYL 1H PYRROL 2 YLAMINO)BUT 2 ENOIC ACID ETHYL ESTER; 3 [3 CYANO 5 (4 FLUOROPHENYL) 1 PHENYL 1H PYRROL 2 YLAMINO]BUT 2 ENOIC ACID ETHYL ESTER; 3 [3 CYANO 5 (4 METHOXYPHENYL) 1 PHENYL 1H PYRROL 2 YLAMINO]BUT 2 ENOIC ACID ETHYL ESTER; 3 [5 (4 BROMOPHENYL) 3 CYANO 1 PHENYL 1H PYRROL 2 YLAMINO]BUT 2 ENOIC ACID ETHYL ESTER; 4 AMINO 2 (4 BROMOPHENYL) 6 METHYL 1 PHENYL 1H PYRROLO[2,3 B]PYRIDINE 5 CARBOXYLIC ACID ETHYL ESTER; 4 AMINO 2 (4 FLUOROPHENYL) 6 METHYL 1 PHENYL 1H PYRROLO[2,3 B]PYRIDINE 5 CARBOXYLIC ACID ETHYL ESTER; 4 AMINO 2 (4 METHOXYPHENYL) 6 METHYL 1 PHENYL 1H PYRROLO[2,3 B]PYRIDINE 5 CARBOXYLIC ACID ETHYL ESTER; 4 AMINO 6 METHYL 1,2 DIPHENYL 1H PYRROLO[2,3 B]PYRIDINE 5 CARBOXYLIC ACID ETHYL ESTER; BACTERIUM LIPOPOLYSACCHARIDE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEW DRUG; PROPENYLAMINOPYRROLE DERIVATIVE; PYRROLE DERIVATIVE; PYRROLO[2,3 B]PYRIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADMINISTRATION, ORAL; ANIMALS; ESCHERICHIA COLI; INJECTIONS, INTRAPERITONEAL; LIPOPOLYSACCHARIDES; MALE; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; PYRIDINES; PYRROLES; RATS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; TUMOR NECROSIS FACTOR DECOY RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 1242269373     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200300773     Document Type: Article

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