Identification of novel ethanol-sensitive genes by expression profiling

Pharmacology and Therapeutics

Volumn 92, Issue 2-3, 2001, Pages 123-134

  Rahman, Sajida ^a   Miles, Michael F ^a  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

Author keywords

Alcoholism; Ethanol; Gene expression; Microarray; Neural cells

Indexed keywords

ALCOHOL; CHAPERONE; MESSENGER RNA; MYELIN; NEUROENDOCRINE SPECIFIC PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; TROPOMYOSIN;

BEHAVIOR; CONCENTRATION RESPONSE; DIFFERENTIAL DISPLAY; DNA MICROARRAY; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HUMAN; HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; TECHNOLOGY;

CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION;

EID: 0035726695     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(01)00163-2     Document Type: Review

References (84)

1. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
2. The significance of digital gene expression profiles
3. Stimulation of synaptosomal free radical production by fatty acids: Relation to esterification and to degree of unsaturation
4. Knowledge-based analysis of microarray gene expression data by using support vector machines
5. A receptor subunit mRNAs: Relationship to genetic differences in ethanol withdrawal seizure severity
6. Ethanol increases the expression of functional delta-opioid receptors in neuroblastoma x glioma NG108-15 hybrid cells
7. Ethanol increases δ-opioid receptor gene expression in neuronal cell lines
8. Differential expression of mitochondrial NADH dehydrogenase in ethanol-treated rat brain: Revealed by differential display
9. Computational methods for the identification of differential and coordinated gene expression
10. Studies on the effect of ethanol on eucaryotic protein synthesis in vitro
11. Use of a cDNA microarray to analyse gene expression patterns in human cancer
12. Exploring the metabolic and genetic control of gene expression on a genomic scale
13. A receptor subunit peptide levels in rat cortex during chronic ethanol consumption and withdrawal
14. Linear modeling of mRNA expression levels during CNS development and injury
15. Cluster analysis and display of genome-wide expression patterns
16. Data management and analysis for gene expression arrays
17. Increased expression of mitochondrial genes in human alcoholic brain revealed by differential display
18. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: Common adaptations among cross-sensitizing agents
19. Ethanol increases tyrosine hydroxylase gene expression in N1E-115 neuroblastoma cells
20. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
21. Alcoholism: A possible G-protein disorder
22. Exploring expression data: Identification and analysis of coexpressed genes
23. Statistical analysis of array expression data as applied to the problem of tamoxifen resistance
24. Norepinephrine and serotonin receptors in the paraventricular nucleus interactively modulate ethanol consumption
25. The effect of ethanol on HSP70 in cultured rat glial cells and in brain areas of rat pups exposed to ethanol in utero
26. Fundamental patterns underlying gene expression profiles: Simplicity from complexity
27. Interaction of ethanol with inducers of glucose-regulated stress proteins: Ethanol potentiates induction of GRP78 transcription
28. Functional discovery via a compendium of expression profiles
29. The transcriptional program in the response of human fibroblasts to serum
30. Preparation of cDNA from single cells and subcellular regions
31. Drug abuse: Hedonic homeostatic dysregulation
32. Ethanol-induced retention of nascent proteins in rat hepatocytes is accompanied by altered distribution of the small GTP-binding protein rab2
33. Molecular characterization of fetal alcohol syndrome using mRNA differential display
34. Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations
35. Gene expression in human alcoholism: Microarray analysis of frontal cortex
36. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
37. Expression monitoring by hybridization to high-density oligonucleotide arrays
38. Ethanol inhibition of neuronal glutamate receptor function
39. Drug target validation and identification of secondary drug target effects using DNA microarrays
40. Ethanol regulates calcium channels in clonal neural cells
41. A receptor gene expression
42. A and glycine receptors
43. Alcohol's effects on gene expression
44. Neurologic complications of alcoholism and alcohol abuse
45. Mechanisms of neuronal adaptation to ethanol: Ethanol induces Hsc70 gene transcription in NG108-15 neuroblastom x glioma cells
46. Ethanol-responsive genes in neural cell cultures
47. Phosducin-like protein (PhLP): An ethanol-responsive potential modulator of G-protein function
48. Ethanol-responsive genes in neural cells include the molecular chaperones GRP78 and GRP94
49. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
50. s mRNA
51. Ethanol increases cytochrome P450-2E1 and induces oxidative stress in astrocytes
52. A receptor α subunit mRNAs in the rat cerebral cortex
53. Molecular and cellular basis of addiction
54. Restricted expression of the actin-regulatory protein, tropomyosin, defines distinct boundaries, evaginating neuroepithelium, and choroid plexus forerunners during early CNS development
55. Differential display of ethanol-induced gene in N18TG2 cells
56. Molecular portraits of human breast tumours
57. Changes in in vivo rates of protein synthesis on free and membrane-bound polysomes in rat brain during the development of physical dependence on ethanol and after the withdrawal of ethanol
58. Nucleic acid and protein synthesis inhibition in developing brain by ethanol in the absence of hypothermia
59. Principal components analysis to summarize microarray experiments: Application to sporulation time series
60. Systematic variation in gene expression patterns in human cancer cell lines
61. Identification of neuroendocrine-specific protein as an ethanol-regulated gene with mRNA differential display
62. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
63. Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes
64. Inhibition of G-protein βγ-subunit functions by phosducin-like protein
65. Identification of a C-terminal binding site for G-protein βγ-subunits in phosducin-like protein
66. Neuroendocrine-specific protein C (NSP-C): Subcellular localization and differential expression in relation to NSP-A
67. Molecular interactions on microarrays
68. Discrimination of fibroblast subtypes by multivariate analysis of gene expression
69. 1-mediated cyclic AMP formation by a murine neuroblastoma clone
70. Ethanol stimulates γ-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes
71. Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
72. Interaction of phosducin-like protein with G protein βγ subunits
73. Expression profiling of neural cells reveals specific patterns of ethanol-responsive gene expression
74. Alcohol and GABA-benzodiazepine receptor function
75. Analysis of gene expression data using self-organizing maps
76. Subtractive cloning of complementary DNAs and analysis of messenger RNAs with regional heterogeneous distributions in primate cortex
77. Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus
78. In vivo modulation of 73 kDa heat shock cognate and 78 kDa glucose-regulating protein gene expression in rat liver and brain by ethanol
79. Molecular analysis of expression in rat brain of NSP-A, a novel neuroendocrine-specific protein of the endoplasmic reticulum
80. Computational aspects of expression data
81. A receptors expressed in Xenopus oocytes
82. Characterization of promoter elements mediating ethanol regulation of hsc70 gene transcription
83. Searching for evidence of altered gene expression: A comment on statistical analysis of microarray data
84. Large-scale gene expression data analysis: A new challenge to computational biologists