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Volumn 288, Issue 2 57-2, 2005, Pages

VEGF receptor antagonism blocks arteriogenesis, but only partially inhibits angiogenesis, in skeletal muscle of exercise-trained rats

Author keywords

F1t; Kinase insert domain containing receptor; Receptor tyrosine kinase inhibition; Treadmill running; Vascular endothelial growth factor

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; N (4 BROMO 2 FLUOROPHENYL) 6 METHOXY 7 [2 (1H 1,2,3 TRIAZOL 1 YL)ETHOXY] 4 QUINAZOLINAMINE; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 12344330190     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00786.2004     Document Type: Article
Times cited : (73)

References (57)
  • 1
    • 0035260068 scopus 로고    scopus 로고
    • Angiogenesis induced by electrical stimulation is mediated by angiotensin II and VEGF
    • Amaral SL, Linderman JR, Morse MM, and Greene AS. Angiogenesis induced by electrical stimulation is mediated by angiotensin II and VEGF. Microcirculation 8: 57-67, 2001.
    • (2001) Microcirculation , vol.8 , pp. 57-67
    • Amaral, S.L.1    Linderman, J.R.2    Morse, M.M.3    Greene, A.S.4
  • 2
    • 0034829216 scopus 로고    scopus 로고
    • Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training
    • Amaral SL, Papanek PE, and Greene AS. Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training. Am J Physiol Heart Circ Physiol 281: H1163-H1169, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Amaral, S.L.1    Papanek, P.E.2    Greene, A.S.3
  • 3
    • 0028288687 scopus 로고
    • Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs
    • Banai S, Jaklitsch MT, Shou M, Lazarous DF, Scheinowitz M, Biro S, Epstein SE, and Unger EF. Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs. Circulation 89: 2183-2189, 1994.
    • (1994) Circulation , vol.89 , pp. 2183-2189
    • Banai, S.1    Jaklitsch, M.T.2    Shou, M.3    Lazarous, D.F.4    Scheinowitz, M.5    Biro, S.6    Epstein, S.E.7    Unger, E.F.8
  • 5
    • 0142245805 scopus 로고    scopus 로고
    • Modulation of physiological angiogenesis in skeletal muscle by mechanical forces: Involvement of VEGF and metalloproteinases
    • Brown MD and Hudlicka O. Modulation of physiological angiogenesis in skeletal muscle by mechanical forces: involvement of VEGF and metalloproteinases. Angiogenesis 6: 1-14, 2003.
    • (2003) Angiogenesis , vol.6 , pp. 1-14
    • Brown, M.D.1    Hudlicka, O.2
  • 10
    • 0031792206 scopus 로고    scopus 로고
    • Capillary growth in relation to blood flow and performance in overloaded rat skeletal muscle
    • Egginton S, Hudlicka O, Brown MD, Walter H, Weiss JB, and Bate A. Capillary growth in relation to blood flow and performance in overloaded rat skeletal muscle. J Appl Physiol 85: 2025-2032, 1998.
    • (1998) J Appl Physiol , vol.85 , pp. 2025-2032
    • Egginton, S.1    Hudlicka, O.2    Brown, M.D.3    Walter, H.4    Weiss, J.B.5    Bate, A.6
  • 11
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, and LeCouter J. The biology of VEGF and its receptors. Nat Med 9: 669-676, 2003.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 12
    • 0035103678 scopus 로고    scopus 로고
    • Effect of short-term exercise training on angiogenic growth factor gene responses in rats
    • Gavin TP and Wagner PD. Effect of short-term exercise training on angiogenic growth factor gene responses in rats. J Appl Physiol 90: 1219-1226, 2001.
    • (2001) J Appl Physiol , vol.90 , pp. 1219-1226
    • Gavin, T.P.1    Wagner, P.D.2
  • 15
    • 0028788730 scopus 로고
    • VEGF gene expression is upregulated in electrically stimulated rat skeletal muscle
    • Hang J, Kong L, Gu JW, and Adair TH. VEGF gene expression is upregulated in electrically stimulated rat skeletal muscle. Am J Physiol Heart Circ Physiol 269: H1827-H1831, 1995.
    • (1995) Am J Physiol Heart Circ Physiol , vol.269
    • Hang, J.1    Kong, L.2    Gu, J.W.3    Adair, T.H.4
  • 16
    • 0037075812 scopus 로고    scopus 로고
    • Novel 4-anilinoquinazolines with C-7 basic side chains: Design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors
    • Hennequin LF, Stokes ES, Thomas AP, Johnstone C, Ple PA, Ogilvie DJ, Dukes M, Wedge SR, Kendrew J, and Curwen JO. Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors. J Med Chem 45: 1300-1312, 2002.
    • (2002) J Med Chem , vol.45 , pp. 1300-1312
    • Hennequin, L.F.1    Stokes, E.S.2    Thomas, A.P.3    Johnstone, C.4    Ple, P.A.5    Ogilvie, D.J.6    Dukes, M.7    Wedge, S.R.8    Kendrew, J.9    Curwen, J.O.10
  • 18
  • 20
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, and Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309, 1989.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 21
    • 0037405671 scopus 로고    scopus 로고
    • Angiogenic growth factor expression in rat skeletal muscle in response to exercise training
    • Lloyd PG, Prior BM, Yang HT, and Terjung RL. Angiogenic growth factor expression in rat skeletal muscle in response to exercise training. Am J Physiol Heart Circ Physiol 284: H1668-H1678, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Lloyd, P.G.1    Prior, B.M.2    Yang, H.T.3    Terjung, R.L.4
  • 22
    • 0035661833 scopus 로고    scopus 로고
    • Arteriogenesis and angiogenesis in rat ischemic hindlimb: Role of nitric oxide
    • Lloyd PG, Yang HT, and Terjung RL. Arteriogenesis and angiogenesis in rat ischemic hindlimb: role of nitric oxide. Am J Physiol Heart Circ Physiol 281: H2528-H2538, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Lloyd, P.G.1    Yang, H.T.2    Terjung, R.L.3
  • 24
    • 0020806141 scopus 로고
    • Blood flow to different skeletal muscle fiber types during contraction
    • Mackie BG and Terjung RL. Blood flow to different skeletal muscle fiber types during contraction. Am J Physiol Heart Circ Physiol 245: H265-H275, 1983.
    • (1983) Am J Physiol Heart Circ Physiol , vol.245
    • Mackie, B.G.1    Terjung, R.L.2
  • 25
    • 0034687598 scopus 로고    scopus 로고
    • Ischemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide
    • Matsunage T, Warltier DC, Weihrauch DW, Moniz M, Tessmer J, and Chilian WM. Ischemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide. Circulation 102: 3098-3103, 2000.
    • (2000) Circulation , vol.102 , pp. 3098-3103
    • Matsunage, T.1    Warltier, D.C.2    Weihrauch, D.W.3    Moniz, M.4    Tessmer, J.5    Chilian, W.M.6
  • 26
    • 0141992249 scopus 로고    scopus 로고
    • Differential expression of Flk-1 and Flt-1 in rat skeletal muscle in response to chronic ischaemia: Favourable effect of muscle activity
    • Milkiewicz M, Hudlicka O, Verhaeg J, Egginton S, and Brown MD. Differential expression of Flk-1 and Flt-1 in rat skeletal muscle in response to chronic ischaemia: favourable effect of muscle activity. Clin Sci (Lond) 105: 473-482, 2003.
    • (2003) Clin Sci (Lond) , vol.105 , pp. 473-482
    • Milkiewicz, M.1    Hudlicka, O.2    Verhaeg, J.3    Egginton, S.4    Brown, M.D.5
  • 28
    • 9344224614 scopus 로고    scopus 로고
    • Time course of changes in collateral blood flow, and isolated vessel size and gene expression following femoral artery occlusion in the rat
    • First published July 22; doi: 10.1152/ajpheart.00398.2004
    • Prior BM, Lloyd PG, Ren J, Li H, Yang HT, Laughlin MH, and Terjung RL. Time course of changes in collateral blood flow, and isolated vessel size and gene expression following femoral artery occlusion in the rat. Am J Physiol Heart Circ Physiol. First published July 22, 2004; doi: 10.1152/ajpheart.00398. 2004.
    • (2004) Am J Physiol Heart Circ Physiol
    • Prior, B.M.1    Lloyd, P.G.2    Ren, J.3    Li, H.4    Yang, H.T.5    Laughlin, M.H.6    Terjung, R.L.7
  • 29
    • 4344583344 scopus 로고    scopus 로고
    • What makes vessels grow with exercise training?
    • Prior BM, Yang HT, and Terjung RL. What makes vessels grow with exercise training? J Appl Physiol 97: 1119-1128, 2004.
    • (2004) J Appl Physiol , vol.97 , pp. 1119-1128
    • Prior, B.M.1    Yang, H.T.2    Terjung, R.L.3
  • 30
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • Quinn TP, Peters KG, De Vries C, Ferrara N, and Williams LT. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 90: 7533-7537, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7533-7537
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 34
    • 0000876311 scopus 로고
    • The histochemical demonstration of alkaline phosphatase activity with indoxyl phosphate
    • Seligman AM, Heymann H, and Barrnett RJ. The histochemical demonstration of alkaline phosphatase activity with indoxyl phosphate. J Histochem Cytochem 2: 441-442, 1954.
    • (1954) J Histochem Cytochem , vol.2 , pp. 441-442
    • Seligman, A.M.1    Heymann, H.2    Barrnett, R.J.3
  • 35
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, and Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845, 1992.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 36
    • 0036965433 scopus 로고    scopus 로고
    • The kinase insert domain-contraining receptor (KDR) is regulated by shear stress
    • Staalesen T, Risberg B, and Mattsson E. The kinase insert domain-contraining receptor (KDR) is regulated by shear stress. Scand Cardiovasc J 36: 368-372, 2002.
    • (2002) Scand Cardiovasc J , vol.36 , pp. 368-372
    • Staalesen, T.1    Risberg, B.2    Mattsson, E.3
  • 37
    • 4844228637 scopus 로고    scopus 로고
    • Capillary regression in vascular endothelial growth factor-deficient skeletal muscle
    • Tang K, Breen EC, Gerber HP, Ferrara N, and Wagner PD. Capillary regression in vascular endothelial growth factor-deficient skeletal muscle. Physiol Genomics 18: 63-69, 2004.
    • (2004) Physiol Genomics , vol.18 , pp. 63-69
    • Tang, K.1    Breen, E.C.2    Gerber, H.P.3    Ferrara, N.4    Wagner, P.D.5
  • 38
  • 39
    • 0030444979 scopus 로고    scopus 로고
    • Nitric oxide maintains dilation of immature and mature collaterals in rat hindlimb
    • Unthank JL, Nixon JC, and Dalsing MC. Nitric oxide maintains dilation of immature and mature collaterals in rat hindlimb. J Vasc Res 33: 471-479, 1996.
    • (1996) J Vasc Res , vol.33 , pp. 471-479
    • Unthank, J.L.1    Nixon, J.C.2    Dalsing, M.C.3
  • 40
    • 0035895715 scopus 로고    scopus 로고
    • Stimulation of arteriogenesis: A new concept for the treatment of arterial occlusive disease
    • Van Royen N, Piek JJ, Buschmann I, Hoefer I, Voskuil M, and Schaper W. Stimulation of arteriogenesis: a new concept for the treatment of arterial occlusive disease. Cardiovasc Res 49: 543-553, 2001.
    • (2001) Cardiovasc Res , vol.49 , pp. 543-553
    • Van Royen, N.1    Piek, J.J.2    Buschmann, I.3    Hoefer, I.4    Voskuil, M.5    Schaper, W.6
  • 42
    • 0032547763 scopus 로고    scopus 로고
    • Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: Role of flt-1
    • Wang H and Keiser JA. Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: role of flt-1. Circ Res 83: 832-840, 1998.
    • (1998) Circ Res , vol.83 , pp. 832-840
    • Wang, H.1    Keiser, J.A.2
  • 44
    • 0029058231 scopus 로고
    • Collateral development and angiogenesis after major artery ligation does not alter hindquarter vascular reactivity in conscious rabbits
    • Ward JE and Angus JA. Collateral development and angiogenesis after major artery ligation does not alter hindquarter vascular reactivity in conscious rabbits. J Cardiovasc Pharmacol 26: 96-106, 1995.
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 96-106
    • Ward, J.E.1    Angus, J.A.2
  • 47
    • 0029990658 scopus 로고    scopus 로고
    • Basic fibroblast growth factor increases collateral blood flow in rats with femoral arterial ligation
    • Yang HT, Deschenes MR, Ogilvie RW, and Terjung RL. Basic fibroblast growth factor increases collateral blood flow in rats with femoral arterial ligation. Circ Res 79: 62-69, 1996.
    • (1996) Circ Res , vol.79 , pp. 62-69
    • Yang, H.T.1    Deschenes, M.R.2    Ogilvie, R.W.3    Terjung, R.L.4
  • 48
    • 0033918682 scopus 로고    scopus 로고
    • Efficacy and specificity of bFGF increased collateral flow in experimental peripheral arterial insufficiency
    • Yang HT, Feng Y, Allen LA, Protter A, and Terjung RL. Efficacy and specificity of bFGF increased collateral flow in experimental peripheral arterial insufficiency. Am J Physiol Heart Circ Physiol 278: H1966-H1973, 2000.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Yang, H.T.1    Feng, Y.2    Allen, L.A.3    Protter, A.4    Terjung, R.L.5
  • 49
    • 0033695471 scopus 로고    scopus 로고
    • Prior exercise training increases collateral-dependent blood flow in rats after acute femoral artery occlusion
    • Yang HT, Laughlin MH, and Terjung RL. Prior exercise training increases collateral-dependent blood flow in rats after acute femoral artery occlusion. Am J Physiol Heart Circ Physiol 279: H1890-H1897, 2000.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Yang, H.T.1    Laughlin, M.H.2    Terjung, R.L.3
  • 50
    • 0028158862 scopus 로고
    • Peripheral adaptations in trained aged rats with femoral artery stenosis
    • Yang HT, Ogilvie RW, and Terjung RL. Peripheral adaptations in trained aged rats with femoral artery stenosis. Circ Res 74: 235-243, 1994.
    • (1994) Circ Res , vol.74 , pp. 235-243
    • Yang, H.T.1    Ogilvie, R.W.2    Terjung, R.L.3
  • 51
    • 0028840046 scopus 로고
    • Heparin increases exercise-induced collateral blood flow in rats with femoral artery ligation
    • Yang HT, Ogilvie RW, and Terjung RL. Heparin increases exercise-induced collateral blood flow in rats with femoral artery ligation. Circ Res 76: 448-456, 1995.
    • (1995) Circ Res , vol.76 , pp. 448-456
    • Yang, H.T.1    Ogilvie, R.W.2    Terjung, R.L.3
  • 53
    • 33750865883 scopus 로고    scopus 로고
    • Exercise training enhances basic fibroblast growth factor-induced collateral blood flow
    • Yang HT, Ogilvie RW, and Terjung RL. Exercise training enhances basic fibroblast growth factor-induced collateral blood flow. Am J Physiol Heart Circ Physiol 274: H2053-H2061, 1998.
    • (1998) Am J Physiol Heart Circ Physiol , vol.274
    • Yang, H.T.1    Ogilvie, R.W.2    Terjung, R.L.3
  • 54
    • 0036083225 scopus 로고    scopus 로고
    • Prior exercise training produces NO-dependent increases in collateral blood flow after acute arterial occlusion
    • Yang HT, Ren J, Laughlin MH, and Terjung RL. Prior exercise training produces NO-dependent increases in collateral blood flow after acute arterial occlusion. Am J Physiol Heart Circ Physiol 282: H301-H310, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Yang, H.T.1    Ren, J.2    Laughlin, M.H.3    Terjung, R.L.4
  • 55
    • 0027172598 scopus 로고
    • Angiotensin converting enzyme inhibition increases collateral-dependent muscle blood flow
    • Yang HT and Terjung RL. Angiotensin converting enzyme inhibition increases collateral-dependent muscle blood flow. J Appl Physiol 75: 452-457, 1993.
    • (1993) J Appl Physiol , vol.75 , pp. 452-457
    • Yang, H.T.1    Terjung, R.L.2
  • 57
    • 0031655427 scopus 로고    scopus 로고
    • Capillary growth in overloaded, hypertrophic adult rat skeletal muscle: An ultrastructural study
    • Zhou AL, Egginton S, Brown MD, and Hudlicka O. Capillary growth in overloaded, hypertrophic adult rat skeletal muscle: an ultrastructural study. Anat Rec 252: 49-63, 1998.
    • (1998) Anat Rec , vol.252 , pp. 49-63
    • Zhou, A.L.1    Egginton, S.2    Brown, M.D.3    Hudlicka, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.