VEGF121- and bFGF-induced increase in collateral blood flow requires normal nitric oxide production

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 3 49-3, 2001, Pages

  Yang, H T ^a   Yan, Z ^a   Abraham, Judith A ^b   Terjung, Ronald L ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b SCIOS INC   (United States)

Author keywords

Angiogenesis; Microsphere; Peripheral arterial insufficiency; Rat; Vascular remodeling

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL REACTIVITY; COLLATERAL CIRCULATION; CONTROLLED STUDY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM;

EID: 0034966636     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.3.h1097     Document Type: Article

References (37)

1. Blood flows within and among rat muscles as a function of time during high speed treadmill exercise
2. Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb
3. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
4. Role of nitric oxide in the angiogenic response in vitro to basic fibroblast growth factor
5. Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: Dose-response effect of basic fibroblast growth factor
6. Site-specific therapeutic angiogenesis after systemic administration of vascular endothelial growth factor
7. Inhibition of endothelial cell proliferatin and bFGF-induced phenotypic modulation by nitric oxide
8. Hypotensive activity of fibroblast growth factor
9. Molecular and biological properties of vascular endothelial growth factor
10. Exogenous, basal, and flow-reduced nitric oxide production and endothelial cell proliferation
11. Flow-induced arterial enlargement is inhibited by suppression of nitric oxide synthase activity in vivo
12. Review of preclinical and clinical results with vascular endothelial growth factors for therapeutic angiogenesis
13. Angiogenesis but not collateral growth is associated with ischemia after femoral artery occlusion
14. Nitric oxide mediates the mitogenic effects of insulin and vascular endothelial growth factor but not of leptin in endothelial cells
15. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries
16. Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion
17. Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium
18. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia
19. Podokinesis in endothelial cell migration: Role of nitric oxide
20. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
21. Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis
22. Vascular endothelial growth factor-induced endothelial cell migration and proliferatin depend on a nitric oxide-mediated decrease in protein kinase Cδ activity
23. Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells: Synergistic interaction with hypoxia
24. Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia
25. Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo
26. Role of NO in flow-induced remodeling of the rabbit common carotid artery
27. Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium
28. Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia
29. VEGF induces NO-dependent hyperpermeability in coronary venules
30. Basic fibroblast growth factor increases collateral blood flow in rats with femoral arterial ligation
31. Training increases muscle blood flow in rats with peripheral arterial insufficiency
32. bFGF increases collateral blood flow in aged rats with femoral artery ligation
33. Efficacy and specificity of bFGF increased collateral flow in experimental peripheral arterial insufficiency
34. Exercise training enhances basic fibroblast growth factor-induced collateral blood flow
35. Angiotensin-converting enzyme inhibition increases collateral-dependent muscle blood flow
36. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis