Efficacy and specificity of bFGF increased collateral flow in experimental peripheral arterial insufficiency

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 278, Issue 6 47-6, 2000, Pages

  Yang, H T ^a   Feng, Y ^a   Allen, Laura A ^a   Protter, Andrew ^b   Terjung, Ronald L ^a,c  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^b SCIOS INC   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

Basic fibroblast growth factor; Collateral circulation; Growth substances; Muscle blood flow; Vascular remodeling

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DISEASE; ARTICLE; BLOOD FLOW; BLOOD VESSEL OCCLUSION; COLLATERAL CIRCULATION; CONTROLLED STUDY; DOSE RESPONSE; NONHUMAN; PRIORITY JOURNAL; RAT; TREADMILL EXERCISE;

EID: 0033918682     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.278.6.h1966     Document Type: Article

References (31)

1. Arras M, Ito WD, Scholz D, Winkler B, Schaper J, and Schaper W. Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb. J Clin Invest 101: 40-50, 1998.
2. Baffour R, Berman J, Garb JL, Rhee SW, Kaufman J, and Friedmann P. Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: doseresponse effect of basic fibroblast growth factor. J Vasc Surg 16: 181-191, 1992.
3. Bauters C, Asahara T, Zheng LP, Takeshita S, Bunting S, Ferrara N, Symes JF, and Isner JM. Site-specific therapeutic angiogenesis after systemic administration of vascular endothelial growth factor. J Vasc Surg 21: 314-325, 1995.
4. Bauters C, Asahara T, Zheng LP, Takeshita S, Bunting S, Ferrara N, Symes JF, and Isner JM. Physiological assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb. Am J Physiol Heart Circ Physiol 267: H1263-H1271, 1994.
5. Chleboun JO and Martins RN. The development and enhancement of the collateral circulation in an animal model of lower limb ischaemia. Aust NZ J Surg 64: 202-207, 1994.
6. Dinn RF, Yang HT, and Terjung RL. The influence of pentoxifylline and torbafylline on muscle blood flow in animals with peripheral arterial insufficiency. J Clin Pharmacol 30: 704-710, 1990.
7. Dudley GA, Abraham WM, and Terjung RL. Influence of exercise intensity and duration on biochemical adaptations in skeletal muscle. J Appl Physiol 53: 844-850, 1982.
8. Hudlicka O, Brown M, and Egginton S. Angiogenesis in skeletal and cardiac muscle. Physiol Rev 72: 369-417, 1992.
9. Ito WD, Arras M, Scholz D, Winkler B, Htun P, and Schaper W. Angiogenesis but not collateral growth is associated with ischemia after femoral artery occlusion. Am J Physiol Heart Circ Physiol 273: H1255-H1265, 1997.
10. Laughlin MH and Armstrong RB. Muscular blood flow distribution patterns as a function of running speed in rats. Am J Physiol Heart Circ Physiol 243: H296-H306, 1982.
11. Lazarous DF, Shou M, Scheinowitz M, Hodge E, Thirumurti V, Kitsiou AN, Stiber JA, Lobo AD, Hunsberger S, Guetta E, Epstein SE, and Unger EF. Comparative effects of basic fibroblast growth factor and vascular endothelial growth factor on coronary collateral development and the arterial response to injury. Circulation 94: 1074-1082, 1996.
12. Lindner V, Lappi DA, Baird A, Majack RA, and Reidy MA. Role of basic fibroblast growth factor in vascular lesion formation. Circ Res 68: 106-113, 1991.
13. Liu L, Russell SM, and Nicoll CS. Analysis of the role of basic fibroblast growth factor in growth and differentiation of transplanted fetal rat paws and intestines. Endocrinology 126: 1764-1770, 1990.
14. Mackie BG and Terjung RL. Blood flow to different skeletal muscle fiber types during contraction. Am J Physiol Heart Circ Physiol 245: H265-H275, 1983.
15. Mathien GM and Terjung RL. Muscle blood flow in trained rats with peripheral arterial insufficiency. Am J Physiol Heart Circ Physiol 258: H759-H765, 1990.
16. Moscatelli D. Metabolism of receptor-bound and matrix-bound basis fibroblast growth factor by bovine capillary endothelial cells. J Cell Biol 107: 753-759, 1988.
17. Ornitz DM, Herr AB, Nilsson M, Westman J, Svahn C-M, and Waksman G. FGF binding and fgf receptor activation by synthetic heparan-derived di- and trisaccharides. Science 268: 432-436, 1995.
18. Rivard A, Fabre J-E, Silver M, Chen D, Murohara T, Kearney M, Magner M, Asahara T, and Isner J. Age-dependent impairment of angiogenesis. Circulation 99: 111-120, 1999.
19. Schaper W and Ito WD. Molecular mechanisms of coronary collateral vessel growth. Circ Res 79: 911-919, 1996.
20. Steel RGD and Torrie JH. Principles and Procedures of Statistics. New York: McGraw-Hill, 1960.
21. Takeshita S, Rossow ST, Kearney M, Zheng LP, Bauters C, Bunting S, Ferrara N, Symes JF, and Isner JM. Time course of increased cellular proliferation in collateral arteries after administration of vascular endothelial growth factor in a rabbit model of lower limb vascular insufficiency. Am J Pathol 147: 1649-1660, 1995.
22. Takeshita S, Zheng LP, Brogi E, Kearney M, Pu LQ, Bunting S, Ferrara N, Symes JF, and Isner JM. Therapeutic angiogenesis. A single intra-arterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hindlimb model. J Clin Invest 93: 662-670, 1994.
23. Vlodavsky I, Fuks Z, Ishai-Michaeli R, Bashkin P, Levi E, Korner G, Bar-Shavit R, and Klagsbrun M. Extracellular matrix-resident basic flbroblast growth factor: implication for the control of angiogenesis. J Cell Biochem 45: 167-176, 1991.
24. Walder CE, Errett CJ, Bunting S, Lindquist P, Ogez JR, Heinsohn HG, Ferrara N, and Thomas GR. Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia. J Cardiovasc Pharmacol 27: 91-98, 1996.
25. Whalen GF, Shing Y, and Folkman J. The fate of intravenously administered bFGF and the effect of heparin. Growth Factors 1: 157-164, 1989.
26. Yang HT, Deschenes MR, Ogilvie RW, and Terjung RL. Basic fibroblast growth factor increases collateral blood flow in rats with femoral arterial ligation. Circ Res 76: 62-69, 1996.
27. Yang HT, Dinn RF, and Terjung RL. Training increases muscle blood flow in rats with peripheral arterial insufficiency. J Appl Physiol 69: 1353-1359, 1990.
28. Yang HT and Feng Y. bFGF increases collateral blood flow in aged rats with femoral artery ligation. Am J Physiol Heart Circ Physiol 278: H85-H93, 2000.
29. Yang HT, Ogilvie RW, and Terjung RL. Exercise training enhances basic fibroblast growth factor-induced collateral blood flow. Am J Physiol Heart Circ Physiol 274: H2053-H2061, 1998.
30. Yang HT, Ogilvie RW, and Terjung RL. Heparin increases exercise-induced collateral blood flow in rats with femoral artery ligation. Circ Res 76: 448-456, 1995.
31. Yang HT and Terjung RL. Angiotensin-converting enzyme inhibition increases collateral-dependent muscle blood flow. J Appl Physiol 75: 452-457, 1993.