Artificial chromosomes: Ideal vectors?

Trends in Biotechnology

Volumn 18, Issue 5, 2000, Pages 218-223

  Brown, William R A ^a   Mee, P Joe ^b   Hong Shen, Ming ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; CENTROMERE; CHROMOSOME REPLICATION; CHROMOSOME STRUCTURE; DNA SEQUENCE; FIBROBLAST; GENE EXPRESSION; GENE REPLICATION; GENE THERAPY; MITOSIS; NONHUMAN; PLANT; PRIORITY JOURNAL; REVIEW; YEAST;

ANIMALS; CHROMOSOMES; CHROMOSOMES, ARTIFICIAL, YEAST; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC TECHNIQUES; GENETIC VECTORS; HUMANS; MAMMALS; PLANTS; PLASMODIUM FALCIPARUM;

MAMMALIA; SACCHAROMYCETALES;

EID: 0034193593     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-7799(00)01438-4     Document Type: Review

References (22)

1. Murray A.W.et al. Chromosome length controls mitotic chromosome segregation in yeast. Cell. 45:1986;529-536.
2. Blackburn E.H., Szostak J.W. The molecular structure of centromeres and telomeres. Annu. Rev. Biochem. 53:1984;163-194.
3. Heller R.et al. Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage. Proc. Natl. Acad. Sci. U. S. A. 93:1996;7125-7130.
4. Mills W.et al. Generation of an approximately 2.4 Mb human X centromere-based minichromosome by targeted telomere-associated chromosome fragmentation in DT40. Hum. Mol. Genet. 8:1999;751-761.
5. Shen M.H.et al. Human mini-chromosomes in mouse embryonal stem cells. Hum. Mol. Genet. 6:1997;1375-1382.
6. Shen M.H.et al. A structurally defined mini-chromosome vector for the mouse germ line. Curr. Biol. 10:1999;31-34.
7. Farr C.et al. Functional re-introduction of human telomeres into mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 88:1991;7006-7010.
8. Barnett M.A.et al. Telomere directed fragmentation of mammalian chromosomes. Nucleic Acids Res. 21:1993;27-36.
9. Hanish J.P.et al. Stringent sequence requirements for the formation of human telomeres. Proc. Natl. Acad. Sci. U. S. A. 91:1994;8861-8865.
10. duSart D.et al. A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA. Nat. Genet. 16:1997;144-153.
11. Larin Z.et al. A method for linking yeast artificial chromosomes. Nucleic Acids Res. 24:1996;4192-4196.
12. Marschall P.et al. Transfer of YACs up to 2.3 Mb intact into human cells with polyethylenimine. Gene Ther. 6:1999;1634-1637.
13. Harrington J.J.et al. Formation of de novo centromeres and construction of first-generation human artificial microchromosomes. Nat. Genet. 15:1997;345-355.
14. Ikeno M.et al. Construction of YAC-based mammalian artificial chromosomes. Nat. Biotechnol. 16:1998;431-439.
15. Taylor S.S.et al. Analysis of extrachromosomal structures containing human centromeric alphoid satellite DNA sequences in mouse cells. Chromosoma. 105:1996;70-81.
16. Somerville C., Somerville S. Plant functional genomics. Science. 285:1999;380-383.
17. Bowman S.et al. The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. Nature. 400:1999;532-538.
18. Smith A.J.H.et al. A site directed chromosomal translo cation induced in embryonic stem cells by Cre-loxP recombination. Nat. Genet. 9:1995;376-385.
19. Wijmenga C.et al. Chromosome 4q DNA rearrangements associated with facioscapulohumeral muscular dystrophy. Nat. Genet. 2:1992;26-30.
20. Tomizuka K.et al. Functional expression and germ line transmission of a human chromosome fragment in chimeric mice. Nat. Genet. 16:1997;133-143.
21. Tomizuka K.et al. Double trans-chromosomic mice. maintenance of two individual human chromosome fragments containing Ig heavy and k loci and expression of fully human antibodies Proc. Natl. Acad. Sci. U. S. A. 97:2000;722-727.
22. Hernandez D.et al. Transchromosomal mouse embryonal stem cell lines and chimeric mice that contain freely segregating fragments of human chromosome 21. Hum. Mol. Genet. 8:1999;923-933.