-
1
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau in to tangles of paired helical filaments/straight filaments
-
A. Alonso, T. Zaidi, M. Novak, I. Grundke-Iqbal, and K. Iqbal Hyperphosphorylation induces self-assembly of tau in to tangles of paired helical filaments/straight filaments Proc. Natl. Acad. Sci. 98 2001 6923 6928
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 6923-6928
-
-
Alonso, A.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
2
-
-
9444296174
-
Highly discriminating distance based topological index
-
A.T. Balaban Highly discriminating distance based topological index Chem. Phys. Lett. 89 1982 399 404
-
(1982)
Chem. Phys. Lett.
, vol.89
, pp. 399-404
-
-
Balaban, A.T.1
-
3
-
-
33845378719
-
Applications of graph theory in chemistry
-
A.T. Balaban Applications of graph theory in chemistry J. Chem. Inf. Comput. Sci. 25 1985 334 343
-
(1985)
J. Chem. Inf. Comput. Sci.
, vol.25
, pp. 334-343
-
-
Balaban, A.T.1
-
4
-
-
0001090251
-
The smallest graphs, trees and 4-trees with degenerate topological index
-
A.T. Balaban, and L.B. Quinar The smallest graphs, trees and 4-trees with degenerate topological index J. Math. Chem. 14 1983 163 233
-
(1983)
J. Math. Chem.
, vol.14
, pp. 163-233
-
-
Balaban, A.T.1
Quinar, L.B.2
-
6
-
-
0023202542
-
Use of molecular complexity indices in predictive pharmacology and toxicology: A QSAR approach (review article)
-
S.C. Basak Use of molecular complexity indices in predictive pharmacology and toxicology: a QSAR approach (review article) Med. Sci. Res. 15 1987 605
-
(1987)
Med. Sci. Res.
, vol.15
, pp. 605
-
-
Basak, S.C.1
-
7
-
-
0028321225
-
Molecular similarity and risk assessment: Analog selection and property estimation using graph invariants
-
S.C. Basak, and G.D. Grunwald Molecular similarity and risk assessment: analog selection and property estimation using graph invariants SAR QSAR Environ. Res. 2 1994 289 307
-
(1994)
SAR QSAR Environ. Res.
, vol.2
, pp. 289-307
-
-
Basak, S.C.1
Grunwald, G.D.2
-
8
-
-
0002398505
-
Estimation of lipophilicity from molecular structural similarity
-
S.C. Basak, and G.D. Grunwald Estimation of lipophilicity from molecular structural similarity New J. Chem. 19 1995 231 237
-
(1995)
New J. Chem.
, vol.19
, pp. 231-237
-
-
Basak, S.C.1
Grunwald, G.D.2
-
9
-
-
0021278802
-
Comparative study of lipophilicity versus topological molecular descriptors in biological correlations
-
S.C. Basak, D.K. Harriss, and V.R. Magnuson Comparative study of lipophilicity versus topological molecular descriptors in biological correlations J. Pharm. Sci. 73 1984 429 437
-
(1984)
J. Pharm. Sci.
, vol.73
, pp. 429-437
-
-
Basak, S.C.1
Harriss, D.K.2
Magnuson, V.R.3
-
10
-
-
45949126191
-
Topological indices: Their nature, mutual relatedness, and applications
-
S.C. Basak, V.R. Magnuson, G.J. Niemi, R.R. Regal, and G.D. Veith Topological indices: their nature, mutual relatedness, and applications Math. Model. 8 1987 300 305
-
(1987)
Math. Model.
, vol.8
, pp. 300-305
-
-
Basak, S.C.1
Magnuson, V.R.2
Niemi, G.J.3
Regal, R.R.4
Veith, G.D.5
-
11
-
-
0000422818
-
Optimal characterization of structure for prediction of properties
-
S.C. Basak, G.J. Niemi, and G.D. Veith Optimal characterization of structure for prediction of properties J. Math. Chem. 4 1990 185 205
-
(1990)
J. Math. Chem.
, vol.4
, pp. 185-205
-
-
Basak, S.C.1
Niemi, G.J.2
Veith, G.D.3
-
12
-
-
0028391743
-
Application of graph theoretical parameters in quantifying molecular similarity and structure-activity studies
-
S.C. Basak, S. Bertelsen, and G. Grunwald Application of graph theoretical parameters in quantifying molecular similarity and structure-activity studies J. Chem. Inf. Comput. Sci. 34 1994 270 276
-
(1994)
J. Chem. Inf. Comput. Sci.
, vol.34
, pp. 270-276
-
-
Basak, S.C.1
Bertelsen, S.2
Grunwald, G.3
-
13
-
-
0035224478
-
Neurofibrillary tangles and tau phosphorylation
-
J.P. Brion, M. Anderton, R. dayanandan, K. Leroy, S. Lovestone, J.N. Octave, L. Pradier, N. Touchnet, and G. Tremp Neurofibrillary tangles and tau phosphorylation Biochem. Soc. Symp. 67 2001 81 88
-
(2001)
Biochem. Soc. Symp.
, vol.67
, pp. 81-88
-
-
Brion, J.P.1
Anderton, M.2
Dayanandan, R.3
Leroy, K.4
Lovestone, S.5
Octave, J.N.6
Pradier, L.7
Touchnet, N.8
Tremp, G.9
-
14
-
-
33845379303
-
Atom pairs as molecular features in structure-activity studies: Definition and applications
-
R.E. Carhart, D.H. Smith, and R. Venkataraghavan Atom pairs as molecular features in structure-activity studies: definition and applications J. Chem. Inf. Comput. Sci. 25 1985 64 73
-
(1985)
J. Chem. Inf. Comput. Sci.
, vol.25
, pp. 64-73
-
-
Carhart, R.E.1
Smith, D.H.2
Venkataraghavan, R.3
-
15
-
-
0033815037
-
Inhibition of tau phosphorylation: A new therapeutic strategy for the treatment of Alzheimer's disease and other neurodegenerative disorders
-
A. Castro, and A. Martinez Inhibition of tau phosphorylation: a new therapeutic strategy for the treatment of Alzheimer's disease and other neurodegenerative disorders Expert Opin. Ther. Pat. 10 2000 1519 1527
-
(2000)
Expert Opin. Ther. Pat.
, vol.10
, pp. 1519-1527
-
-
Castro, A.1
Martinez, A.2
-
16
-
-
0034329543
-
Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and CDK5 are key participants
-
D.B. Flaherty, J.P. Soria, H.G. Tomasiewicz, and J.G. Wood Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and CDK5 are key participants J. Neurosci. Res. 62 2000 463 472
-
(2000)
J. Neurosci. Res.
, vol.62
, pp. 463-472
-
-
Flaherty, D.B.1
Soria, J.P.2
Tomasiewicz, H.G.3
Wood, J.G.4
-
17
-
-
0033087740
-
Superpendentic index: A novel topological descriptor for prediction of biological activity
-
S. Gupta, M. Singh, and A.K. Madan Superpendentic index: a novel topological descriptor for prediction of biological activity J. Chem. Inf. Comput. Sci. 39 1999 272 277
-
(1999)
J. Chem. Inf. Comput. Sci.
, vol.39
, pp. 272-277
-
-
Gupta, S.1
Singh, M.2
Madan, A.K.3
-
18
-
-
0034798063
-
Predicting anti-HIV activity: Computational approach using a novel topological descriptor
-
S. Gupta, M. Singh, and A.K. Madan Predicting anti-HIV activity: computational approach using a novel topological descriptor J. Comput. Aided Mol. Des. 15 2001 671 678
-
(2001)
J. Comput. Aided Mol. Des.
, vol.15
, pp. 671-678
-
-
Gupta, S.1
Singh, M.2
Madan, A.K.3
-
19
-
-
0037084418
-
Application of graph theory: Relationship of eccentric connectivity index and Wiener's index with anti-inflammatory activity
-
S. Gupta, M. Singh, and A.K. Madan Application of graph theory: Relationship of eccentric connectivity index and Wiener's index with anti-inflammatory activity J. Math. Anal. Appl. 266 2002 259 268
-
(2002)
J. Math. Anal. Appl.
, vol.266
, pp. 259-268
-
-
Gupta, S.1
Singh, M.2
Madan, A.K.3
-
20
-
-
0002658584
-
Algebric characterization of skeletal branching
-
I. Gutman, and M. Randic Algebric characterization of skeletal branching Chem. Phys. Lett. 47 1977 15 19
-
(1977)
Chem. Phys. Lett.
, vol.47
, pp. 15-19
-
-
Gutman, I.1
Randic, M.2
-
22
-
-
19244367909
-
Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35: Implications for Alzheimer's disease
-
F. Hernández, M. Pérez, J.J. Lucas, A.M. Mata, R. Bhat, and J. Avila Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35: implications for Alzheimer's disease J. Biol. Chem. 279 5 2004 3801 3806
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.5
, pp. 3801-3806
-
-
Hernández, F.1
Pérez, M.2
Lucas, J.J.3
Mata, A.M.4
Bhat, R.5
Avila, J.6
-
23
-
-
0001219776
-
Topological index; Newly proposed quantity characterizing the topological nature of structure of isomers of saturated hydrocarbons
-
H. Hosoya Topological index; newly proposed quantity characterizing the topological nature of structure of isomers of saturated hydrocarbons Bull. Chem. Soc. Jpn. 44 1971 2332 2337
-
(1971)
Bull. Chem. Soc. Jpn.
, vol.44
, pp. 2332-2337
-
-
Hosoya, H.1
-
24
-
-
0001650426
-
Topological index as strong sorting device for coding chemical structure
-
H. Hosoya Topological index as strong sorting device for coding chemical structure J. Chem. Doc. 12 1972 181 183
-
(1972)
J. Chem. Doc.
, vol.12
, pp. 181-183
-
-
Hosoya, H.1
-
25
-
-
0026731425
-
Tau protein kinase-I converts normal tau protein into a68-like component of paired helical filaments
-
K. Ishiguro, M. Takamatsu, K. Tomizawa, A. Omori, M. Takahashi, M. Arioka, T. Uchida, and K. Imahori Tau protein kinase-I converts normal tau protein into a68-like component of paired helical filaments J. Biol. Chem. 267 1992 10897 10901
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 10897-10901
-
-
Ishiguro, K.1
Takamatsu, M.2
Tomizawa, K.3
Omori, A.4
Takahashi, M.5
Arioka, M.6
Uchida, T.7
Imahori, K.8
-
26
-
-
0027692921
-
Traditional topological indexes vs electronic, geometrical, and combined molecular descriptors in QSAR/QSPR research
-
A.R. Katritzky, and E.V. Gordeeva Traditional topological indexes vs electronic, geometrical, and combined molecular descriptors in QSAR/QSPR research J. Chem. Inf. Comput. Sci. 33 1993 835 857
-
(1993)
J. Chem. Inf. Comput. Sci.
, vol.33
, pp. 835-857
-
-
Katritzky, A.R.1
Gordeeva, E.V.2
-
28
-
-
9144227739
-
Topological models for the prediction of cyclin-dependent kinase-2 inhibitory activity of aminothiazoles
-
V. Kumar, and A.K. Madan Topological models for the prediction of cyclin-dependent kinase-2 inhibitory activity of aminothiazoles MATCH Commun. Math. Comput. Chem. 51 2004 59 78
-
(2004)
MATCH Commun. Math. Comput. Chem.
, vol.51
, pp. 59-78
-
-
Kumar, V.1
Madan, A.K.2
-
29
-
-
0032820869
-
Tau protein as a therapeutic target in Alzheimer's disease and other neurodegenerative disorders
-
A.J. Larner Tau protein as a therapeutic target in Alzheimer's disease and other neurodegenerative disorders Expert Opin. Ther. Pat. 9 1999 1359 1370
-
(1999)
Expert Opin. Ther. Pat.
, vol.9
, pp. 1359-1370
-
-
Larner, A.J.1
-
30
-
-
0035808457
-
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease: A property common to most cyclin-dependent kinase inhibitors?
-
S. Leclerc, M. Garnier, R. Hoessel, D. Marko, J.A. Bibb, G.L. Snyder, P. Greengard, J. Biernat, Y.Z. Wu, E.M. Mandelkow, G. Eisenbrand, and L. Meijer Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease: a property common to most cyclin-dependent kinase inhibitors? J. Biol. Chem. 276 1 2001 251 260
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.1
, pp. 251-260
-
-
Leclerc, S.1
Garnier, M.2
Hoessel, R.3
Marko, D.4
Bibb, J.A.5
Snyder, G.L.6
Greengard, P.7
Biernat, J.8
Wu, Y.Z.9
Mandelkow, E.M.10
Eisenbrand, G.11
Meijer, L.12
-
31
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3 beta conditional transgenic mice
-
J.L. Lucas, F. Hernandez, P. Gomez-Ramos, M.A. Moran, R. Hen, and J. Avila Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3 beta conditional transgenic mice EMBO J. 20 2001 37 39
-
(2001)
EMBO J.
, vol.20
, pp. 37-39
-
-
Lucas, J.L.1
Hernandez, F.2
Gomez-Ramos, P.3
Moran, M.A.4
Hen, R.5
Avila, J.6
-
32
-
-
0037075791
-
First non-ATP glycogen synthase kinase-3 β (GSK3β) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease
-
A. Martinez, A. Mercedes, A. Castro, C. Perez, and F.J. Moreno First non-ATP glycogen synthase kinase-3 β (GSK3β) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease J. Med. Chem. 45 2002 1292 1299
-
(2002)
J. Med. Chem.
, vol.45
, pp. 1292-1299
-
-
Martinez, A.1
Mercedes, A.2
Castro, A.3
Perez, C.4
Moreno, F.J.5
-
33
-
-
0032850599
-
Distribution of active glycogen synthase kinase-3 beta (GSK-3 beta) in brains staged for Alzheimer disease neurofibrillary changes
-
J.J. Pei, E. Braak, H. Braak, I. Grundke-Iqbal, K. Iqbal, B. Winblad, and R.F. Cowburn Distribution of active glycogen synthase kinase-3 beta (GSK-3 beta) in brains staged for Alzheimer disease neurofibrillary changes J. Neuropathol. Exp. Neurol. 58 1999 1010 1019
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 1010-1019
-
-
Pei, J.J.1
Braak, E.2
Braak, H.3
Grundke-Iqbal, I.4
Iqbal, K.5
Winblad, B.6
Cowburn, R.F.7
-
34
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
C.J. Phiel, C.A. Wilson, V.M. Lee, and P.S. Klein GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides Nature 423 6938 2003 435 439
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
35
-
-
8644280181
-
On characterization of molecular branching
-
M. Randic On characterization of molecular branching J. Am. Chem. Soc. 97 1974 6609 6615
-
(1974)
J. Am. Chem. Soc.
, vol.97
, pp. 6609-6615
-
-
Randic, M.1
-
36
-
-
0000733018
-
Molecular profiles: Novel geometry-dependent molecular descriptors
-
M. Randic Molecular profiles: novel geometry-dependent molecular descriptors New J. Chem. 19 1995 781 791
-
(1995)
New J. Chem.
, vol.19
, pp. 781-791
-
-
Randic, M.1
-
37
-
-
0024017036
-
Search for useful graph theoretical invariants of molecular structure
-
M. Randic, P.J. Hansen, and P.C. Jurs Search for useful graph theoretical invariants of molecular structure J. Chem. Inf. Comput. Sci. 28 1988 60 68
-
(1988)
J. Chem. Inf. Comput. Sci.
, vol.28
, pp. 60-68
-
-
Randic, M.1
Hansen, P.J.2
Jurs, P.C.3
-
39
-
-
0002851282
-
The evolution of the concept of molecular similarity
-
M.A. Johnson G. Maggiora Wiley New York
-
D.H. Rouvray The evolution of the concept of molecular similarity M.A. Johnson G. Maggiora Concepts and Applications of Molecular Similarity 1990 Wiley New York pp. 15-42
-
(1990)
Concepts and Applications of Molecular Similarity
-
-
Rouvray, D.H.1
-
40
-
-
0344926464
-
Divergent roles of GSK3 and CDK5 in APP processing
-
J. Ryder, Y. Su, F. Liu, B. Li, Y. Zhou, and B. Ni Divergent roles of GSK3 and CDK5 in APP processing Biochem. Biophys. Res. Commun. 312 4 2003 922 929
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, Issue.4
, pp. 922-929
-
-
Ryder, J.1
Su, Y.2
Liu, F.3
Li, B.4
Zhou, Y.5
Ni, B.6
-
41
-
-
0012986327
-
Application of graph theory: Relationship of molecular connectivity index Wiener's index and eccentric connectivity index with diuretic activity
-
S. Sardana, and A.K. Madan Application of graph theory: relationship of molecular connectivity index Wiener's index and eccentric connectivity index with diuretic activity MATCH Commun. Math. Comput. Chem. 43 2001 85 98
-
(2001)
MATCH Commun. Math. Comput. Chem.
, vol.43
, pp. 85-98
-
-
Sardana, S.1
Madan, A.K.2
-
42
-
-
0036347566
-
Application of graph theory: Relationship of antimycobacterial activity of quinolone derivatives with eccentric connectivity index and Zagreb group parameter
-
S. Sardana, and A.K. Madan Application of graph theory: relationship of antimycobacterial activity of quinolone derivatives with eccentric connectivity index and Zagreb group parameter MATCH Commun. Math. Comput. Chem. 45 2002 35 53
-
(2002)
MATCH Commun. Math. Comput. Chem.
, vol.45
, pp. 35-53
-
-
Sardana, S.1
Madan, A.K.2
-
43
-
-
0036706729
-
Predicting anticonvulsant activity of benzamides/benzylamines: Computational approach using topological descriptors
-
S. Sardana, and A.K. Madan Predicting anticonvulsant activity of benzamides/benzylamines: computational approach using topological descriptors J. Comput. Aid. Mol. Des. 16 2002 1 6
-
(2002)
J. Comput. Aid. Mol. Des.
, vol.16
, pp. 1-6
-
-
Sardana, S.1
Madan, A.K.2
-
44
-
-
0036977012
-
Predicting anti HIV activity of TIBO derivarives: A computational approach using a novel topological descriptors
-
S. Sardana, and A.K. Madan Predicting anti HIV activity of TIBO derivarives: a computational approach using a novel topological descriptors J. Mol. Model. 8 2002 258 265
-
(2002)
J. Mol. Model.
, vol.8
, pp. 258-265
-
-
Sardana, S.1
Madan, A.K.2
-
45
-
-
0346123167
-
Relationship of Wiener's index and adjacent eccentric distance sum index with nitroxide free radicals and their precursors as modifiers against oxidative damages
-
S. Sardana, and A.K. Madan Relationship of Wiener's index and adjacent eccentric distance sum index with nitroxide free radicals and their precursors as modifiers against oxidative damages J. Mol. Str. (Theochem.) 638 2003 41 49
-
(2003)
J. Mol. Str. (Theochem.)
, vol.638
, pp. 41-49
-
-
Sardana, S.1
Madan, A.K.2
-
46
-
-
0002938511
-
Eccentric connectivity index: A novel highly discriminating topological descriptor for structure property and structure activity studies
-
V. Sharma, R. Goswami, and A.K. Madan Eccentric connectivity index: a novel highly discriminating topological descriptor for structure property and structure activity studies J. Chem. Inf. Comput. Sci. 37 1997 273 282
-
(1997)
J. Chem. Inf. Comput. Sci.
, vol.37
, pp. 273-282
-
-
Sharma, V.1
Goswami, R.2
Madan, A.K.3
-
47
-
-
0034731461
-
Glycogen synthase kinase-3 beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice
-
K. Spittaels, C. Van Den Haute, J. Van Drope, H. Geerts, M. Mercken, K. Bruynseels, R. Lasrado, K. Vandezande, I. Laenen, J. Van Lint, J. Vandenheede, D. Moechars, R. Loos, and F. Van Leuven Glycogen synthase kinase-3 beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice J. Biol. Chem. 275 2000 41340 41349
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41340-41349
-
-
Spittaels, K.1
Van Den Haute, C.2
Van Drope, J.3
Geerts, H.4
Mercken, M.5
Bruynseels, K.6
Lasrado, R.7
Vandezande, K.8
Laenen, I.9
Van Lint, J.10
Vandenheede, J.11
Moechars, D.12
Loos, R.13
Van Leuven, F.14
-
49
-
-
36849142106
-
Influence of interatomic forces on paraffin properties
-
H. Wiener Influence of interatomic forces on paraffin properties J. Chem. Phys. 15 1947 766
-
(1947)
J. Chem. Phys.
, vol.15
, pp. 766
-
-
Wiener, H.1
-
50
-
-
33947441259
-
Correlation of heat of isomerization and difference in heat of vaporization of isomers among paraffin hydrocarbons
-
H. Wiener Correlation of heat of isomerization and difference in heat of vaporization of isomers among paraffin hydrocarbons J. Am. Chem. Soc. 69 1947 2636 2638
-
(1947)
J. Am. Chem. Soc.
, vol.69
, pp. 2636-2638
-
-
Wiener, H.1
-
51
-
-
0029737421
-
Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I glycogen synthase kinase-3 beta and cyclin-dependent kinase-5, a component of TPK II
-
H. Yamaguchi, K. Ishiguro, T. Uchida, A. Takashima, C.A. Lemere, and K. Imahori Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I glycogen synthase kinase-3 beta and cyclin-dependent kinase-5, a component of TPK II Acta Neuropathol. 92 1996 232 241
-
(1996)
Acta Neuropathol.
, vol.92
, pp. 232-241
-
-
Yamaguchi, H.1
Ishiguro, K.2
Uchida, T.3
Takashima, A.4
Lemere, C.A.5
Imahori, K.6
|