-
1
-
-
0010731747
-
-
Marcel Decker, New York
-
Welling P. G., Lasagna L., and Banakar, U. V., The Drug Development Process: Increasing Efficiency and Cost Effectiveness, Marcel Decker, New York, 1996, pp vii-viii.
-
(1996)
The Drug Development Process: Increasing Efficiency and Cost Effectiveness
-
-
Welling, P.G.1
Lasagna, L.2
Banakar, U.V.3
-
2
-
-
0000422818
-
Optimal characterization of structure for prediction of properties
-
Basak S. C., Niemi G. J., and Veith G. D., Optimal characterization of structure for prediction of properties, J. Math. Chem. (1990) 4, 185-205.
-
(1990)
J. Math. Chem.
, vol.4
, pp. 185-205
-
-
Basak, S.C.1
Niemi, G.J.2
Veith, G.D.3
-
3
-
-
33845279214
-
Chemical applications of graph theory
-
Hansen P.J., and Jurs P.C., Chemical applications of graph theory, J. Chem. Educ. (1988) 65, 574-580.
-
(1988)
J. Chem. Educ.
, vol.65
, pp. 574-580
-
-
Hansen, P.J.1
Jurs, P.C.2
-
4
-
-
0345177880
-
-
CRC Press: Boca Raton
-
Trinajstic N., Chemical Graph Theory, CRC Press: Boca Raton, 1983, Vol. I, pp. 31-34.
-
(1983)
Chemical Graph Theory
, vol.1
, pp. 31-34
-
-
Trinajstic, N.1
-
5
-
-
0001219776
-
Topological index; newly proposed quantity characterizing the topological nature of structure of isomers of saturated hydrocarbons
-
Hosoya H., Topological index; newly proposed quantity characterizing the topological nature of structure of isomers of saturated hydrocarbons, Bull. Chem. Soc. Jpn. (1971) 44, 2332-2337.
-
(1971)
Bull. Chem. Soc. Jpn.
, vol.44
, pp. 2332-2337
-
-
Hosoya, H.1
-
6
-
-
0001650426
-
Topological index as strong sorting device for coding chemical structure
-
Hosoya H., Topological index as strong sorting device for coding chemical structure, J. Chem. Doc. (1972) 12, 181-183.
-
(1972)
J. Chem. Doc.
, vol.12
, pp. 181-183
-
-
Hosoya, H.1
-
7
-
-
8644280181
-
On characterization of molecular branching
-
Randic M., On characterization of molecular branching. J. Am. Chem. Soc. (1974) 97, 6609-6615.
-
(1974)
J. Am. Chem. Soc.
, vol.97
, pp. 6609-6615
-
-
Randic, M.1
-
9
-
-
0002977109
-
Steric fit in QSAR
-
Balaban A. T., Chiriac A., Motoc I., and Simon Z., Steric fit in QSAR, Lect. Notes Chem., (1980) 15, 22-27.
-
(1980)
Lect. Notes Chem.
, vol.15
, pp. 22-27
-
-
Balaban, A.T.1
Chiriac, A.2
Motoc, I.3
Simon, Z.4
-
10
-
-
9444296174
-
Highly discriminating distance based topological index
-
Balaban A. T., Highly discriminating distance based topological index, Chem. Phys. Lett. (1982) 89, 399-404.
-
(1982)
Chem. Phys. Lett.
, vol.89
, pp. 399-404
-
-
Balaban, A.T.1
-
11
-
-
33845378719
-
Applications of graph theory in chemistry
-
Balaban A. T., Applications of graph theory in chemistry, J. Chem. Inf. Comput. Sci. (1985) 25, 334-343.
-
(1985)
J. Chem. Inf. Comput. Sci.
, vol.25
, pp. 334-343
-
-
Balaban, A.T.1
-
12
-
-
0001090251
-
The smallest graphs, trees and 4-trees with degenerate topological index
-
Balaban A. T., and Quinar L. B., The smallest graphs, trees and 4-trees with degenerate topological index, J. Math. Chem. (1983) 14, 163-233.
-
(1983)
J. Math. Chem.
, vol.14
, pp. 163-233
-
-
Balaban, A.T.1
Quinar, L.B.2
-
13
-
-
36849142106
-
Influence of interatomic forces on paraffin properties
-
Wiener H., Influence of interatomic forces on paraffin properties, J. Chem. Phys., (1974) 15, 766-766.
-
(1974)
J. Chem. Phys.
, vol.15
, pp. 766-766
-
-
Wiener, H.1
-
14
-
-
33947441259
-
Correlation of heat of isomerization and difference in heat of vaporization of isomers among paraffin hydrocarbons
-
Wiener H., Correlation of heat of isomerization and difference in heat of vaporization of isomers among paraffin hydrocarbons, J. Am. Chem. Soc. (1947) 69, 2636-2638.
-
(1947)
J. Am. Chem. Soc.
, vol.69
, pp. 2636-2638
-
-
Wiener, H.1
-
15
-
-
0027659228
-
Wiener matrix; source of novel graph invariants
-
Randic M., Guo X., Oxely T., and Krishnapriyan H., Wiener matrix; source of novel graph invariants, J. Chem. Inf. Comput. Sci. (1993) 33, 709-716.
-
(1993)
J. Chem. Inf. Comput. Sci.
, vol.33
, pp. 709-716
-
-
Randic, M.1
Guo, X.2
Oxely, T.3
Krishnapriyan, H.4
-
16
-
-
0002658584
-
Algebric characterization of skeletal branching
-
Gutman I., and Randic M., Algebric characterization of skeletal branching, Chem. Phys. Lett. (1977) 47, 15-19.
-
(1977)
Chem. Phys. Lett.
, vol.47
, pp. 15-19
-
-
Gutman, I.1
Randic, M.2
-
17
-
-
36749120371
-
Graph theory and molecular orbitals.XII. Acyclic polyenes
-
Gutman I., Ruscic B., Trinajstic N., and Wicox C. F., Graph theory and molecular orbitals.XII. Acyclic polyenes, J. Chem. Phys. (1975) 62, 3399-3405.
-
(1975)
J. Chem. Phys.
, vol.62
, pp. 3399-3405
-
-
Gutman, I.1
Ruscic, B.2
Trinajstic, N.3
Wicox, C.F.4
-
18
-
-
0002938511
-
Eccentric connectivity index: A novel highly discriminating topological descriptor for structure property and structure activity studies
-
Sharma V., Goswami R., and Madan A. K., Eccentric connectivity index: A novel highly discriminating topological descriptor for structure property and structure activity studies, J. Chem. Inf. Comput. Sci. (1997) 37, 273-282.
-
(1997)
J. Chem. Inf. Comput. Sci.
, vol.37
, pp. 273-282
-
-
Sharma, V.1
Goswami, R.2
Madan, A.K.3
-
19
-
-
0037084418
-
Application of graph theory: Relationship of eccentric connectivity index and Wiener's index with anti-inflammatory activity
-
Gupta S., Singh M., and Madan A. K., Application of graph theory: Relationship of eccentric connectivity index and Wiener's index with anti-inflammatory activity, J. Math. Anal. Applic. (2002) 266, 259-268.
-
(2002)
J. Math. Anal. Applic.
, vol.266
, pp. 259-268
-
-
Gupta, S.1
Singh, M.2
Madan, A.K.3
-
20
-
-
0036347566
-
Application of graph theory: Relationship of antimycobacterial activity of quinolone derivatives with eccentric connectivity index and Zagreb group parameter
-
Sardana S., and Madan A. K., Application of graph theory: Relationship of antimycobacterial activity of quinolone derivatives with eccentric connectivity index and Zagreb group parameter, MATCH Commun. Math. Comput. Chem. (2002) 45, 36-53.
-
(2002)
MATCH Commun. Math. Comput. Chem.
, vol.45
, pp. 36-53
-
-
Sardana, S.1
Madan, A.K.2
-
21
-
-
1542455505
-
Application of graph theory: Relationship of molecular connectivity index, Wiener's index and eccentric connectivity index with diuretic activity
-
Sardana S., and Madan A. K., Application of graph theory: Relationship of molecular connectivity index, Wiener's index and eccentric connectivity index with diuretic activity, MATCH Commun. Math. Comput. Chem. (2001) 45, 36-53.
-
(2001)
MATCH Commun. Math. Comput. Chem.
, vol.45
, pp. 36-53
-
-
Sardana, S.1
Madan, A.K.2
-
22
-
-
0344393019
-
Perspectives on cancer therapy: Cell cycle blockers and perturbators
-
Dobashi Y., Takehana T., and Ooi A., Perspectives on cancer therapy: cell cycle blockers and perturbators, Curr. Med. Chem. (2003) 10, 2549-2558.
-
(2003)
Curr. Med. Chem.
, vol.10
, pp. 2549-2558
-
-
Dobashi, Y.1
Takehana, T.2
Ooi, A.3
-
23
-
-
0034807335
-
Recent advances and new directions in the discovery and development of cyclin-dependent kinase inhibitors
-
Fischer P. M., Recent advances and new directions in the discovery and development of cyclin-dependent kinase inhibitors, Curr. Opin. Drug Discov. Devel. (2001) 4, 623-634.
-
(2001)
Curr. Opin. Drug Discov. Devel.
, vol.4
, pp. 623-634
-
-
Fischer, P.M.1
-
24
-
-
0028491074
-
The cell cycle kinases
-
Pines J., The cell cycle kinases, Semin. Cancer Biol. (1994) 5, 305-313.
-
(1994)
Semin. Cancer Biol.
, vol.5
, pp. 305-313
-
-
Pines, J.1
-
25
-
-
0029849620
-
Cancer cell cycles
-
Sherr C., Cancer cell cycles, Science (1996) 274, 1672-1674.
-
(1996)
Science
, vol.274
, pp. 1672-1674
-
-
Sherr, C.1
-
26
-
-
0027938209
-
Cyclins and cancer II: Cyclins and CDK inhibitors come of age
-
Hunter T., and Pines J., Cyclins and cancer II: Cyclins and CDK inhibitors come of age, Cell (1994) 79, 573-582.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
27
-
-
9144261813
-
Olomoucine ii, new effective CDK inhibitor with strong cytotoxic properties
-
Lenobel R., Havli L., Kryscaron P.V., Otyepka M., and Strnad M., Olomoucine ii, new effective CDK inhibitor with strong cytotoxic properties, Scientific World J. (2001) 1 (Suppl 3), 128.
-
(2001)
Scientific World J.
, vol.1
, Issue.3 SUPPL.
, pp. 128
-
-
Lenobel, R.1
Havli, L.2
Kryscaron, P.V.3
Otyepka, M.4
Strnad, M.5
-
28
-
-
0029286242
-
Cyclins, CDKs and Cancer
-
Pines J., Cyclins, CDKs and Cancer, Semin. Cancer Biol. (1995) 6, 63-72.
-
(1995)
Semin. Cancer Biol.
, vol.6
, pp. 63-72
-
-
Pines, J.1
-
29
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell L. H., and Kastan M. B., Cell cycle control and cancer, Science (1994) 266, 1821-1828.
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
30
-
-
0141569038
-
Cell cycle progression without cyclin E/CDK2. Breaking down the walls of dogma
-
Gladden A. B., and Diehl J. A, Cell cycle progression without cyclin E/CDK2. Breaking down the walls of dogma, Cancer Cell (2003) 4, 160-162.
-
(2003)
Cancer Cell
, vol.4
, pp. 160-162
-
-
Gladden, A.B.1
Diehl, J.A.2
-
31
-
-
0030895204
-
When checkpoint fails
-
Paulovich A. G., Toczyski D. P., and Hartwell L. H., When checkpoint fails, Cell (1997) 88, 315-321.
-
(1997)
Cell
, vol.88
, pp. 315-321
-
-
Paulovich, A.G.1
Toczyski, D.P.2
Hartwell, L.H.3
-
32
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
Pardee A. B., A restriction point for control of normal animal cell proliferation, Proc. Natl. Acad. Sci. U. S. A. (1974) 71, 1286-1290.
-
(1974)
Proc. Natl. Acad. Sci. U. S. A.
, vol.71
, pp. 1286-1290
-
-
Pardee, A.B.1
-
33
-
-
0037302850
-
The use of cyclin-dependent kinase inhibitors alone or in combination with established cytotoxic drugs in cancer chemotherapy
-
Grant S., and Roberts J. D., The use of cyclin-dependent kinase inhibitors alone or in combination with established cytotoxic drugs in cancer chemotherapy, Drug Resist. Updat. (2003) 6, 15-26.
-
(2003)
Drug Resist. Updat.
, vol.6
, pp. 15-26
-
-
Grant, S.1
Roberts, J.D.2
-
34
-
-
0037194619
-
Discovery of aminothiazole inhibitors of cyclin-dependant kinase 2: Synthesis, X-ray crystallographic analysis and biological activities
-
Kim K. S., Kimball D. S., Misra R. N., Rawlins D. B., Hunt J. T., Xiao H. Y., Lu S., Qian L., Han W. C., Shan W., Mitt M., Cai Z. W., Poss M. A., Zhu H., Sack J. S., Tokarski J. S., Chang C. Y., Pavletich N., Kamath A., Humphreys W. G., Marathe P., Bursuker I., Keller K. A., Roongta U., Batorsky R., Mulheron J. G., Bol D., Fairchild C. R., Lee F. Y., and Webster K. R., Discovery of aminothiazole inhibitors of cyclin-dependant kinase 2: synthesis, X-ray crystallographic analysis and biological activities, J. Med. Chem. (2002) 45, 3905-3927.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3905-3927
-
-
Kim, K.S.1
Kimball, D.S.2
Misra, R.N.3
Rawlins, D.B.4
Hunt, J.T.5
Xiao, H.Y.6
Lu, S.7
Qian, L.8
Han, W.C.9
Shan, W.10
Mitt, M.11
Cai, Z.W.12
Poss, M.A.13
Zhu, H.14
Sack, J.S.15
Tokarski, J.S.16
Chang, C.Y.17
Pavletich, N.18
Kamath, A.19
Humphreys, W.G.20
Marathe, P.21
Bursuker, I.22
Keller, K.A.23
Roongta, U.24
Batorsky, R.25
Mulheron, J.G.26
Bol, D.27
Fairchild, C.R.28
Lee, F.Y.29
Webster, K.R.30
more..
-
35
-
-
0034798063
-
Predicting anti-HIV activity: Computational approach using a novel topological descriptor
-
Gupta S., Singh M., and Madan A. K., Predicting anti-HIV activity: Computational approach using a novel topological descriptor, J. Comput. Aid. Mol. Des. (2001) 15, 671-678.
-
(2001)
J. Comput. Aid. Mol. Des.
, vol.15
, pp. 671-678
-
-
Gupta, S.1
Singh, M.2
Madan, A.K.3
-
37
-
-
0037242297
-
Chemical and biological profile of dual Cdk1 and Cdk2 inhibitors
-
Ruetz S., Fabbro D., Zimmermann J., Meyer T., and Gray N., Chemical and biological profile of dual Cdk1 and Cdk2 inhibitors. Curr. Med. Chem. Anti-Canc. Agents (2003) 3, 1-14.
-
(2003)
Curr. Med. Chem. Anti-Canc. Agents
, vol.3
, pp. 1-14
-
-
Ruetz, S.1
Fabbro, D.2
Zimmermann, J.3
Meyer, T.4
Gray, N.5
|