Interaction of DNA polymerase I (Klenow fragment) with DNA substrates containing extrahelical bases: Implications for proofreading of frameshift errors during DNA synthesis

Biochemistry

Volumn 38, Issue 9, 1999, Pages 2661-2668

  Lam, Wai Chung ^a   Van Der Schans, Edwin J C ^a   Sowers, Lawrence C ^b   Millar, David P ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

ARTICLE; BASE PAIRING; DNA CLEAVAGE; DNA FLANKING REGION; DNA PROTEIN COMPLEX; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; FLUORESCENCE ANALYSIS; FRAMESHIFT MUTATION; PRIORITY JOURNAL; STEADY STATE;

2-AMINOPURINE; BASE PAIRING; DNA; DNA POLYMERASE I; DNA PRIMERS; EXODEOXYRIBONUCLEASE V; EXODEOXYRIBONUCLEASES; FRAMESHIFT MUTATION; HYDROLYSIS; KINETICS; NUCLEIC ACID HETERODUPLEXES; SUBSTRATE SPECIFICITY; TEMPLATES, GENETIC;

EID: 0033515064     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9820762     Document Type: Article

References (27)

1. Streisinger, G., Okada, J., Emrich, J., Newton, J., Tsugita, A., Terzaghi, E., and Inouye, M. (1966) Cold Spring Harbor Symp. Quant. Biol. 31, 77-84.
2. Ripley, L. S. (1990) Annu. Rev. Genet. 24, 189-213.
3. Kunkel, T. A., and Soni, A. (1988) J. Biol. Chem. 263, 14784-14789.
4. Kunkel, T. A. (1990) Biochemistry 29, 8003-8011.
5. Joyce, C. M., and Steitz, T. A. (1994) Annu. Rev. Biochem. 63, 777-822.
6. Ollis, D. L., Brick, P., Hamlin, R., Xuong, N. G., and Steitz, T. A. (1985) Nature 313, 762-766.
7. Freemont, P. S., Friedman, J. M., Beese, L. S., Sanderson, M., and Steitz, T. A. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 8924-8928.
8. Guest, C. R., Hochstrasser, R. A., Dupuy, C. G., Allen, D. J., Benkovic, S. J., and Millar, D. P. (1991) Biochemistry 30, 8759-8770.
9. Carver, T. E., Hochstrasser, R. A., and Millar, D. P. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 10670-10674.
10. Carver, T. E., and Millar, D. P. (1998) Biochemistry 37, 1898-1904.
11. Lam, W.-C., Van der Schans, E. J. C., Joyce, C. M., and Millar, D. P. (1998) Biochemistry 37, 1513-1522.
12. Gibson, K. J., and Benkovic, S. J. (1987) Nucleic Acids Res. 15, 6455-6467.
13. Eritja, R., Kaplan, B. E., Mhaskar, D., Sowers, L. C., Petruska, J., and Goodman, M. F. (1986) Nucleic Acids Res. 14, 5869-5884.
14. Atkinson, T., and Smith, M. (1984) in Oligonucleotide Synthesis, a Practical Approach (Gait, M. J., Ed.) IRL Press, Washington, DC.
15. Derbyshire, V., Grindley, N. D. F., and Joyce, C. M. (1991) EMBO J. 10, 17-24.
16. O'Connor, D. V., and Philips, D. R. (1988) Time-Correlated Single Photon Counting, p 271, Academic Press, London.
17. Derbyshire, V., Freemont, P., Sanderson, M. R., Beese, L., Friedman, J. M., Joyce, C. M., and Steitz, T. A. (1988) Science 240, 199-201.
18. Ward, D. C., Reich, E., and Stryer, L. (1969) J. Biol. Chem. 244, 1228-1237.
19. Guest, C. R., Hochastrasser, R. A., Sowers, L. C., and Millar, D. P. (1991) Biochemistry 30, 3271-3279.
20. Hochstrasser, R. A., Carver, T. E., Sowers, L. C., and Millar, D. P. (1994) Biochemistry 33, 11971-11979.
21. Bloom, L. B., Otto, M. R., Eritja, R., Reha-Krantz, L. J., Goodman, M. F., and Beechem, J. M. (1994) Biochemistry 33, 7576-7586.
22. Freemont, P. S., Friedman, J. M., Beese, L. S., Sanderson, M. R., and Steitz, T. A. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 8924-8928.
23. Beese, L., Derbyshire, V., and Steitz, T. A. (1993) Science 260, 352-355.
24. Cowart, M., Gibson, K. J., Allen, D. J., and Benkovic, S. J. (1989) Biochemistry 28, 1975-1983.
25. Kuchta, R. D., Mizrahi, V., Benkovic, P. A., Johnson, K. A., and Benkovic, S. J. (1987) Biochemistry 26, 8410.
26. Joyce, C. M., and Steitz, T. A. (1987) Trends Biochem. Sci. 12, 288-292.
27. Allen, D. J., Darke, P. L., and Benkovic, S. J. (1989) Biochemistry 28, 4601-4607.