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Volumn 7, Issue 4, 2004, Pages 479-484

The gastrointestinal tract and glucose tolerance

Author keywords

Gastric emptying; Glucose intolerance; Incretin

Indexed keywords

ADENYLATE KINASE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; GLUCOSE; GLUCAGON; INSULIN; PEPTIDE FRAGMENT; PROTEIN PRECURSOR;

EID: 12244296648     PISSN: 13631950     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mco.0000134375.01310.97     Document Type: Review
Times cited : (30)

References (55)
  • 1
    • 0029935830 scopus 로고    scopus 로고
    • Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of differing degrees of insulin resistance
    • Basu A, Alzaid A, Dinneen S, et al. Effects of a change in the pattern of insulin delivery on carbohydrate tolerance in diabetic and nondiabetic humans in the presence of differing degrees of insulin resistance. J Clin Invest 1996; 97:2351-2361.
    • (1996) J Clin Invest , vol.97 , pp. 2351-2361
    • Basu, A.1    Alzaid, A.2    Dinneen, S.3
  • 2
    • 0020615045 scopus 로고
    • Postprandial glucose and insulin responses to meals containing different carbohydrates in normal and diabetic subjects
    • Bantle JP, Laine DC, Castle GW, et al. Postprandial glucose and insulin responses to meals containing different carbohydrates in normal and diabetic subjects. N Engl J Med 1983; 309:7-12.
    • (1983) N Engl J Med , vol.309 , pp. 7-12
    • Bantle, J.P.1    Laine, D.C.2    Castle, G.W.3
  • 3
    • 0031054198 scopus 로고    scopus 로고
    • Impaired basal glucose effectiveness in NIDDM: Contribution of defects in glucose disappearance and production, measured using an optimized minimal model independent protocol
    • Basu A, Caumo A, Bettini F, et al. Impaired basal glucose effectiveness in NIDDM: contribution of defects in glucose disappearance and production, measured using an optimized minimal model independent protocol. Diabetes 1997; 46:421-432.
    • (1997) Diabetes , vol.46 , pp. 421-432
    • Basu, A.1    Caumo, A.2    Bettini, F.3
  • 4
    • 0023838435 scopus 로고
    • The disposal of an oral glucose load in patients with non-insulin-dependent diabetes
    • Ferrannini E, Simonson DC, Katz LD, et al. The disposal of an oral glucose load in patients with non-insulin-dependent diabetes. Metabolism 1988; 37:79-85.
    • (1988) Metabolism , vol.37 , pp. 79-85
    • Ferrannini, E.1    Simonson, D.C.2    Katz, L.D.3
  • 5
    • 0022467301 scopus 로고
    • Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues
    • Firth RG, Bell PM, Marsh HM, et al. Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues. J Clin Invest 1986; 77:1525-1532.
    • (1986) J Clin Invest , vol.77 , pp. 1525-1532
    • Firth, R.G.1    Bell, P.M.2    Marsh, H.M.3
  • 6
    • 0344549608 scopus 로고    scopus 로고
    • Incretins and their analogues as new antidiabetic drugs
    • Nauck MA, Meier JJ, Creutzfeldt W. Incretins and their analogues as new antidiabetic drugs. Drug News Perspect 2003; 16:413-422. Outline of the therapeutic potential of incretins and their analogues.
    • (2003) Drug News Perspect , vol.16 , pp. 413-422
    • Nauck, M.A.1    Meier, J.J.2    Creutzfeldt, W.3
  • 7
    • 0034111103 scopus 로고    scopus 로고
    • Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes
    • Vella A, Shah P, Basu R, et al. Effect of glucagon-like peptide 1(7-36) amide on glucose effectiveness and insulin action in people with type 2 diabetes. Diabetes 2000; 49:611-617.
    • (2000) Diabetes , vol.49 , pp. 611-617
    • Vella, A.1    Shah, P.2    Basu, R.3
  • 8
  • 9
    • 0028296643 scopus 로고
    • Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal
    • D'Alessio DA, Kahn SE, Leusner CR, Ensinck JW. Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal. J Clin Invest 1994; 93:2263-2266.
    • (1994) J Clin Invest , vol.93 , pp. 2263-2266
    • D'Alessio, D.A.1    Kahn, S.E.2    Leusner, C.R.3    Ensinck, J.W.4
  • 10
    • 0034974254 scopus 로고    scopus 로고
    • Glucose effectiveness: Measurement in diabetic and nondiabetic humans
    • Basu A, Rizza RA. Glucose effectiveness: measurement in diabetic and nondiabetic humans. Exp Clin Endocrinol Diabetes 2001; 109 (Suppl 2):S157-S165.
    • (2001) Exp Clin Endocrinol Diabetes , vol.109 , Issue.2 SUPPL.
    • Basu, A.1    Rizza, R.A.2
  • 11
    • 0032956247 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs
    • Sandhu H, Wiesenthal SR, MacDonald PE, et al. Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs. Diabetes 1999; 48:1045-1053.
    • (1999) Diabetes , vol.48 , pp. 1045-1053
    • Sandhu, H.1    Wiesenthal, S.R.2    MacDonald, P.E.3
  • 12
    • 0035123797 scopus 로고    scopus 로고
    • Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes
    • Vella A, Shah P, Basu R, et al. Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes. Diabetes 2001; 50:565-572.
    • (2001) Diabetes , vol.50 , pp. 565-572
    • Vella, A.1    Shah, P.2    Basu, R.3
  • 13
    • 0028139157 scopus 로고
    • Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle
    • Villanueva-Penacarrillo ML, Alcantara AI, Clemente F, et al. Potent glycogenic effect of GLP-1(7-36)amide in rat skeletal muscle. Diabetologia 1994; 37:1163-1166.
    • (1994) Diabetologia , vol.37 , pp. 1163-1166
    • Villanueva-Penacarrillo, M.L.1    Alcantara, A.I.2    Clemente, F.3
  • 14
    • 0027141309 scopus 로고
    • Presence of glucagon and glucagon-like peptide-1-(7-36)amide receptors in solubilized membranes of human adipose tissue
    • Merida E, Delgado E, Molina LM, et al. Presence of glucagon and glucagon-like peptide-1-(7-36)amide receptors in solubilized membranes of human adipose tissue. J Clin Endocrinol Metab 1993; 77:1654-1657.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1654-1657
    • Merida, E.1    Delgado, E.2    Molina, L.M.3
  • 16
    • 1842329143 scopus 로고    scopus 로고
    • Preserved GLP-I effects on glycogen synthase a activity and glucose metabolism in isolated hepatocytes and skeletal muscle from diabetic rats
    • Morales M, Lopez-Delgado MI, Alcantara A, et al. Preserved GLP-I effects on glycogen synthase a activity and glucose metabolism in isolated hepatocytes and skeletal muscle from diabetic rats. Diabetes 1997; 46:1264-1269.
    • (1997) Diabetes , vol.46 , pp. 1264-1269
    • Morales, M.1    Lopez-Delgado, M.I.2    Alcantara, A.3
  • 17
    • 0030607672 scopus 로고    scopus 로고
    • Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor
    • Knudsen LB, Pridal L. Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur J Pharmacol 1996; 318:429-435.
    • (1996) Eur J Pharmacol , vol.318 , pp. 429-435
    • Knudsen, L.B.1    Pridal, L.2
  • 18
    • 0030779816 scopus 로고    scopus 로고
    • High potency antagonists of the pancreatic glucagon-like peptide-1 receptor
    • Montrose-Rafizadeh C, Yang H, Rodgers BD, et al. High potency antagonists of the pancreatic glucagon-like peptide-1 receptor. J Biol Chem 1997; 272:21201-21206.
    • (1997) J Biol Chem , vol.272 , pp. 21201-21206
    • Montrose-Rafizadeh, C.1    Yang, H.2    Rodgers, B.D.3
  • 19
    • 0031863483 scopus 로고    scopus 로고
    • The inhibitory effect of glucagon-like peptide-1 (7-36)amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36)amide
    • Wettergren A, Wojdemann M, Holst JJ. The inhibitory effect of glucagon-like peptide-1 (7-36)amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36)amide. Peptides 1998; 19:877-882.
    • (1998) Peptides , vol.19 , pp. 877-882
    • Wettergren, A.1    Wojdemann, M.2    Holst, J.J.3
  • 20
    • 0036081143 scopus 로고    scopus 로고
    • GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion
    • Deacon CF, Plamboeck A, Moller S, Holst JJ. GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion. Am J Physiol Endocrinol Metab 2002; 282:E873-E879.
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Deacon, C.F.1    Plamboeck, A.2    Moller, S.3    Holst, J.J.4
  • 21
    • 0036035521 scopus 로고    scopus 로고
    • Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans
    • Vella A, Shah P, Reed AS, et al. Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans. Diabetologia 2002; 45:1410-1415.
    • (2002) Diabetologia , vol.45 , pp. 1410-1415
    • Vella, A.1    Shah, P.2    Reed, A.S.3
  • 22
    • 0026795010 scopus 로고
    • Carbohydrate metabolism in non-insulin-dependent diabetes mellitus
    • Dinneen S, Gerich J, Rizza R. Carbohydrate metabolism in non-insulin-dependent diabetes mellitus. N Engl J Med 1992; 327:707-713.
    • (1992) N Engl J Med , vol.327 , pp. 707-713
    • Dinneen, S.1    Gerich, J.2    Rizza, R.3
  • 23
    • 0029126551 scopus 로고
    • Mechanism of accelerated gastric emptying of liquids and hyperglycemia in patients with type II diabetes mellitus
    • Frank JW, Saslow SB, Camilleri M, et al. Mechanism of accelerated gastric emptying of liquids and hyperglycemia in patients with type II diabetes mellitus. Gastroenterology 1995; 109:755-765.
    • (1995) Gastroenterology , vol.109 , pp. 755-765
    • Frank, J.W.1    Saslow, S.B.2    Camilleri, M.3
  • 24
    • 0037339148 scopus 로고    scopus 로고
    • Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients
    • Gonlachanavit S, Hsu CW, Boden GH, et al. Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients. Dig Dis Sci 2003; 48:488-497. Effectively illustrates the importance of the rate of gastric emptying in the maintenance of glucose tolerance.
    • (2003) Dig Dis Sci , vol.48 , pp. 488-497
    • Gonlachanavit, S.1    Hsu, C.W.2    Boden, G.H.3
  • 25
    • 0034636549 scopus 로고    scopus 로고
    • Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus
    • Chandalia M, Garg A, Lutjohann D, et al. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 2000; 342:1392-1398.
    • (2000) N Engl J Med , vol.342 , pp. 1392-1398
    • Chandalia, M.1    Garg, A.2    Lutjohann, D.3
  • 26
    • 0037712155 scopus 로고    scopus 로고
    • Guar attenuates fall in postprandial blood pressure and slows gastric emptying of oral glucose in type 2 diabetes
    • Russo A, Stevens JE, Wilson T, et al. Guar attenuates fall in postprandial blood pressure and slows gastric emptying of oral glucose in type 2 diabetes. Dig Dis Sci 2003; 48:1221-1229. Illustrates the effect of guar on gastric emptying in glucose tolerance.
    • (2003) Dig Dis Sci , vol.48 , pp. 1221-1229
    • Russo, A.1    Stevens, J.E.2    Wilson, T.3
  • 27
    • 0141682407 scopus 로고    scopus 로고
    • Long-term effects of high dietary fiber intake on glucose tolerance and lipid metabolism in GK rats: Comparison among barley, rice, and cornstarch
    • Li J, Kaneko T, Qin LQ, et al. Long-term effects of high dietary fiber intake on glucose tolerance and lipid metabolism in GK rats: comparison among barley, rice, and cornstarch. Metabolism 2003; 52:1206-1210. Experimental evidence to support the beneficial effects of high dietary fiber.
    • (2003) Metabolism , vol.52 , pp. 1206-1210
    • Li, J.1    Kaneko, T.2    Qin, L.Q.3
  • 28
    • 0037569423 scopus 로고    scopus 로고
    • Postprandial triglycerides in response to high fat: Role of dietary carbohydrate
    • Kriketos AD, Sam W, Schubert T, et al. Postprandial triglycerides in response to high fat: role of dietary carbohydrate. Eur J Clin Invest 2003; 33:383-389. Demonstrates that by stimulating insulin secretion, the addition of carbohydrate to fat can dampen postprandial lipidemia.
    • (2003) Eur J Clin Invest , vol.33 , pp. 383-389
    • Kriketos, A.D.1    Sam, W.2    Schubert, T.3
  • 29
    • 0031664857 scopus 로고    scopus 로고
    • Subcutaneous glucagon-like peptide-1 improves postprandial glycaemic control over a 3-week period in patients with early type 2 diabetes
    • Lond
    • Todd JF, Edwards CM, Ghatei MA, et al. Subcutaneous glucagon-like peptide-1 improves postprandial glycaemic control over a 3-week period in patients with early type 2 diabetes. Clin Sci (Lond) 1998; 95:325-329.
    • (1998) Clin Sci , vol.95 , pp. 325-329
    • Todd, J.F.1    Edwards, C.M.2    Ghatei, M.A.3
  • 30
    • 0037667613 scopus 로고    scopus 로고
    • Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
    • Meier JJ, Gallwitz B, Salmen S, et al. Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. J Clin Endocrinol Metab 2003; 88:2719-2725. Proof that continuous intravenous GLP-1 can delay gastric emptying, suppress glucagon, and increase insulin secretion to improve glucose tolerance in patients with type 2 diabetes.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2719-2725
    • Meier, J.J.1    Gallwitz, B.2    Salmen, S.3
  • 31
    • 0032970549 scopus 로고    scopus 로고
    • Modulation of gastric sensory and motor functions by nitrergic and alpha2-adrenergic agents in humans
    • Thumshirn M, Camilleri M, Choi MG, Zinsmeister AR. Modulation of gastric sensory and motor functions by nitrergic and alpha2-adrenergic agents in humans. Gastroenterology 1999; 116:573-585.
    • (1999) Gastroenterology , vol.116 , pp. 573-585
    • Thumshirn, M.1    Camilleri, M.2    Choi, M.G.3    Zinsmeister, A.R.4
  • 32
    • 0029925139 scopus 로고    scopus 로고
    • Impaired accommodation of proximal stomach to a meal in functional dyspepsia
    • Gilja OH, Hausken T, Wilhelmsen I, Berstad A. Impaired accommodation of proximal stomach to a meal in functional dyspepsia. Dig Dis Sci 1996; 41:689-696.
    • (1996) Dig Dis Sci , vol.41 , pp. 689-696
    • Gilja, O.H.1    Hausken, T.2    Wilhelmsen, I.3    Berstad, A.4
  • 33
    • 0028177577 scopus 로고
    • Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
    • Wettergren A, Petersen H, Orskov C, et al. Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man. Scand J Gastroenterol 1994; 29:501-505.
    • (1994) Scand J Gastroenterol , vol.29 , pp. 501-505
    • Wettergren, A.1    Petersen, H.2    Orskov, C.3
  • 34
    • 0030966001 scopus 로고    scopus 로고
    • Differential effects of subcutaneous GLP-1 on gastric emptying, antroduodenal motility, and pancreatic function in men
    • Schirra J, Kuwert P, Wank U, et al. Differential effects of subcutaneous GLP-1 on gastric emptying, antroduodenal motility, and pancreatic function in men. Proc Assoc Am Physicians 1997; 109:84-97.
    • (1997) Proc Assoc Am Physicians , vol.109 , pp. 84-97
    • Schirra, J.1    Kuwert, P.2    Wank, U.3
  • 35
    • 0036086315 scopus 로고    scopus 로고
    • Effect of GLP-1 on gastric volume, emptying, maximum volume ingested, and postprandial symptoms in humans
    • Delgado-Aros S, Kim DY, Burton DD, et al. Effect of GLP-1 on gastric volume, emptying, maximum volume ingested, and postprandial symptoms in humans. Am J Physiol Gastrointest Liver Physiol 2002; 282:G424-G431.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282
    • Delgado-Aros, S.1    Kim, D.Y.2    Burton, D.D.3
  • 36
    • 0038713668 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 and feeding on gastric volumes in diabetes mellitus with cardio-vagal dysfunction
    • Delgado-Aros S, Vella A, Camilleri M, et al. Effects of glucagon-like peptide-1 and feeding on gastric volumes in diabetes mellitus with cardio-vagal dysfunction. Neurogastroenterol Motil 2003; 15:435-443. Examination of the effects of GLP-1 on gastric function in the presence of autonomic neuropathy.
    • (2003) Neurogastroenterol Motil , vol.15 , pp. 435-443
    • Delgado-Aros, S.1    Vella, A.2    Camilleri, M.3
  • 37
    • 0019184861 scopus 로고
    • Gastric motility 1 year after proximal gastric vagotomy
    • Stadaas JO. Gastric motility 1 year after proximal gastric vagotomy. Scand J Gastroenterol 1980; 15:799-804.
    • (1980) Scand J Gastroenterol , vol.15 , pp. 799-804
    • Stadaas, J.O.1
  • 38
    • 0026093265 scopus 로고
    • Gastric adaptive relaxation and symptoms after vagotomy
    • Hartley MN, Mackie CR. Gastric adaptive relaxation and symptoms after vagotomy. Br J Surg 1991; 78:24-27.
    • (1991) Br J Surg , vol.78 , pp. 24-27
    • Hartley, M.N.1    Mackie, C.R.2
  • 39
    • 0028847792 scopus 로고
    • Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study
    • Hwang JH, Perseghin G, Rothman DL, et al. Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study. J Clin Invest 1995; 95:783-787.
    • (1995) J Clin Invest , vol.95 , pp. 783-787
    • Hwang, J.H.1    Perseghin, G.2    Rothman, D.L.3
  • 40
    • 0028172989 scopus 로고
    • 13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus
    • Cline GW, Rothman DL, Magnusson I, et al. 13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus. J Clin Invest 1994; 94:2369-2376.
    • (1994) J Clin Invest , vol.94 , pp. 2369-2376
    • Cline, G.W.1    Rothman, D.L.2    Magnusson, I.3
  • 41
    • 0034847718 scopus 로고    scopus 로고
    • Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration
    • Vella A, Shah P, Basu R, et al. Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration. Diabetologia 2001; 44:729-737.
    • (2001) Diabetologia , vol.44 , pp. 729-737
    • Vella, A.1    Shah, P.2    Basu, R.3
  • 42
    • 0037569417 scopus 로고    scopus 로고
    • Increased intestinal permeability as a cause of fluctuating postprandial blood glucose levels in Type 1 diabetic patients
    • Damci T, Nuhoglu I, Devranoglu G, et al. Increased intestinal permeability as a cause of fluctuating postprandial blood glucose levels in Type 1 diabetic patients. Eur J Clin Invest 2003; 33:397-401. Interesting observation of increased intestinal permeability in type 1 diabetes that merits further investigation.
    • (2003) Eur J Clin Invest , vol.33 , pp. 397-401
    • Damci, T.1    Nuhoglu, I.2    Devranoglu, G.3
  • 43
    • 0041922363 scopus 로고    scopus 로고
    • Prior exercise enhances passive absorption of intraduodenal glucose
    • Pencek RR, Koyama Y, Lacy DB, et al. Prior exercise enhances passive absorption of intraduodenal glucose. J Appl Physiol 2003; 95:1132-1138. Mechanistic investigation of the effect of exercise on glucose tolerance.
    • (2003) J Appl Physiol , vol.95 , pp. 1132-1138
    • Pencek, R.R.1    Koyama, Y.2    Lacy, D.B.3
  • 44
    • 0030056028 scopus 로고    scopus 로고
    • Effect of prior exercise on the partitioning of an intestinal glucose load between splanchnic bed and skeletal muscle
    • Hamilton KS, Gibbons FK, Bracy DP, et al. Effect of prior exercise on the partitioning of an intestinal glucose load between splanchnic bed and skeletal muscle. J Clin Invest 1996; 98:125-135.
    • (1996) J Clin Invest , vol.98 , pp. 125-135
    • Hamilton, K.S.1    Gibbons, F.K.2    Bracy, D.P.3
  • 45
    • 0026354412 scopus 로고
    • Magnitude of negative arterial-portal glucose gradient alters net hepatic glucose balance in conscious dogs
    • Pagliassotti MJ, Myers SR, Moore MC, et al. Magnitude of negative arterial-portal glucose gradient alters net hepatic glucose balance in conscious dogs. Diabetes 1991; 40:1659-1668.
    • (1991) Diabetes , vol.40 , pp. 1659-1668
    • Pagliassotti, M.J.1    Myers, S.R.2    Moore, M.C.3
  • 46
    • 0036033650 scopus 로고    scopus 로고
    • The role of hepatic portal glucose sensing in modulating responses to hypoglycaemia in man
    • Smith D, Pernet A, Reid H, et al. The role of hepatic portal glucose sensing in modulating responses to hypoglycaemia in man. Diabetologia 2002; 45:1416-1424.
    • (2002) Diabetologia , vol.45 , pp. 1416-1424
    • Smith, D.1    Pernet, A.2    Reid, H.3
  • 47
    • 0020513612 scopus 로고
    • Differential effects of oral, peripheral intravenous, and intraportal glucose on hepatic glucose uptake and insulin and glucagon extraction in conscious dogs
    • Ishida T, Chap Z, Chou J, et al. Differential effects of oral, peripheral intravenous, and intraportal glucose on hepatic glucose uptake and insulin and glucagon extraction in conscious dogs. J Clin Invest 1983; 72:590-601.
    • (1983) J Clin Invest , vol.72 , pp. 590-601
    • Ishida, T.1    Chap, Z.2    Chou, J.3
  • 48
    • 0035434115 scopus 로고    scopus 로고
    • Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor
    • Burcelin R, Da Costa A, Drucker D, Thorens B. Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor. Diabetes 2001; 50:1720-1728.
    • (2001) Diabetes , vol.50 , pp. 1720-1728
    • Burcelin, R.1    Da Costa, A.2    Drucker, D.3    Thorens, B.4
  • 49
    • 0042804811 scopus 로고    scopus 로고
    • Enteral infusion of glucose at rates approximating EGP enhances glucose disposal but does not cause hypoglycemia
    • Zangeneh F, Basu R, Shah P, et al. Enteral infusion of glucose at rates approximating EGP enhances glucose disposal but does not cause hypoglycemia. Am J Physiol Endocrinol Metab 2003; 285:E280-E286. Demonstration that enteral glucose feeding does not cause hypoglycemia in humans but may enhance peripheral glucose disposal.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Zangeneh, F.1    Basu, R.2    Shah, P.3
  • 50
    • 0036326233 scopus 로고    scopus 로고
    • Effect of enteral vs. parenteral glucose delivery on initial splanchnic glucose uptake in nondiabetic humans
    • Vella A, Shah P, Basu R, et al. Effect of enteral vs. parenteral glucose delivery on initial splanchnic glucose uptake in nondiabetic humans. Am J Physiol Endocrinol Metab 2002; 283:E259-E266.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Vella, A.1    Shah, P.2    Basu, R.3
  • 51
    • 0035805218 scopus 로고    scopus 로고
    • Metabolic effects of indinavir in healthy HIV-seronegative men
    • Noor MA, Lo JC, Mulligan K, et al. Metabolic effects of indinavir in healthy HIV-seronegative men. AIDS 2001; 15:F11-F18.
    • (2001) AIDS , vol.15
    • Noor, M.A.1    Lo, J.C.2    Mulligan, K.3
  • 52
    • 0037192590 scopus 로고    scopus 로고
    • Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: A randomized, placebo-controlled study
    • Noor MA, Seneviratne T, Aweeka FT, et al. Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study. AIDS 2002; 16:F1-F8.
    • (2002) AIDS , vol.16
    • Noor, M.A.1    Seneviratne, T.2    Aweeka, F.T.3
  • 53
    • 0037380408 scopus 로고    scopus 로고
    • Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens
    • Woerle HJ, Mariuz PR, Meyer C, et al. Mechanisms for the deterioration in glucose tolerance associated with HIV protease inhibitor regimens. Diabetes 2003; 52:918-925. Mechanistic study of worsening glucose tolerance associated with protease inhibitors.
    • (2003) Diabetes , vol.52 , pp. 918-925
    • Woerle, H.J.1    Mariuz, P.R.2    Meyer, C.3
  • 54
    • 0037227753 scopus 로고    scopus 로고
    • Use of a novel triple-tracer approach to assess postprandial glucose metabolism
    • Basu R, Di Camillo B, Toffolo G, Basu A, Shah P, Vella A, Rizza R, Cobelli C. Use of a novel triple-tracer approach to assess postprandial glucose metabolism. Am J Physiol Endocrinol Metab 2003; 284:E55-E69. Promising new methodology to measure and model glucose metabolism, avoiding the limitations of the minimal model.
    • (2003) Am J Physiol Endocrinol Metab , vol.284
    • Basu, R.1    Di Camillo, B.2    Toffolo, G.3    Basu, A.4    Shah, P.5    Vella, A.6    Rizza, R.7    Cobelli, C.8
  • 55
    • 0038353641 scopus 로고    scopus 로고
    • Mechanisms of the age-associated deterioration in glucose tolerance: Contribution of alterations in insulin secretion, action, and clearance
    • Basu R, Breda E, Oberg AL, et al. Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance. Diabetes 2003; 52:1738-1748. Mechanistic study of the mechanisms by which aging contributes to glucose intolerance.
    • (2003) Diabetes , vol.52 , pp. 1738-1748
    • Basu, R.1    Breda, E.2    Oberg, A.L.3


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