-
1
-
-
0020615045
-
Postprandial glucose and insulin responses to meals containing different carbohydrates in normal and diabetic subjects
-
Bantle, J.P., D.C. Laine, G.W. Castle, J.W. Thomas, B.J. Hoogwerf, and F.C. Goetz. 1983. Postprandial glucose and insulin responses to meals containing different carbohydrates in normal and diabetic subjects. N. Engl. J. Med. 309:7-12.
-
(1983)
N. Engl. J. Med.
, vol.309
, pp. 7-12
-
-
Bantle, J.P.1
Laine, D.C.2
Castle, G.W.3
Thomas, J.W.4
Hoogwerf, B.J.5
Goetz, F.C.6
-
2
-
-
0024590095
-
Relationship between glucose tolerance, insulin secretion, and insulin action in non-obese individuals with varying degrees of glucose tolerance
-
Reaven, G.M., C.B. Hollenbeck, and Y.-D.I. Chen. 1993. Relationship between glucose tolerance, insulin secretion, and insulin action in non-obese individuals with varying degrees of glucose tolerance. Diabetologia. 32:52-55.
-
(1993)
Diabetologia
, vol.32
, pp. 52-55
-
-
Reaven, G.M.1
Hollenbeck, C.B.2
Chen, Y.-D.I.3
-
3
-
-
0022571557
-
Gastric inhibitory polypeptide responses and glucose turnover rates after natural meals in type II diabetic patients
-
Osei, K., J.M. Falko, T.M. O'Dorisio, P.G. Fields, and B. Bossetti. 1986. Gastric inhibitory polypeptide responses and glucose turnover rates after natural meals in type II diabetic patients. J. Clin. Endocrinol. & Metab. 62:325-330.
-
(1986)
J. Clin. Endocrinol. & Metab.
, vol.62
, pp. 325-330
-
-
Osei, K.1
Falko, J.M.2
O'Dorisio, T.M.3
Fields, P.G.4
Bossetti, B.5
-
4
-
-
0022467301
-
Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus: Role of hepatic and extrahepatic tissues
-
Firth, R.G., P.M. Bell, H.M. Marsh, I. Hansen, and R.A. Rizza. 1986. Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus: role of hepatic and extrahepatic tissues. J. Clin. Invest. 77:1525-1532.
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 1525-1532
-
-
Firth, R.G.1
Bell, P.M.2
Marsh, H.M.3
Hansen, I.4
Rizza, R.A.5
-
5
-
-
0023838435
-
The disposal of an oral glucose load in patients with non-insulin-dependent diabetes
-
Ferrannini, E., D.C. Simonson, L.D. Katz, G. Reichard, Jr., S. Bevilacqua, E.J. Barrett, M. Olsson, and R.A. DeFronzo. 1988. The disposal of an oral glucose load in patients with non-insulin-dependent diabetes. Metabolism. 37: 79-85.
-
(1988)
Metabolism
, vol.37
, pp. 79-85
-
-
Ferrannini, E.1
Simonson, D.C.2
Katz, L.D.3
Reichard Jr., G.4
Bevilacqua, S.5
Barrett, E.J.6
Olsson, M.7
DeFronzo, R.A.8
-
6
-
-
0024539271
-
Effects of basal insulin supplementation on disposition of mixed meal in obese patients with NIDDM
-
McMahon, M., H.M. Marsh, and R.A. Rizza. 1989. Effects of basal insulin supplementation on disposition of mixed meal in obese patients with NIDDM. Diabetes. 38:291-303.
-
(1989)
Diabetes
, vol.38
, pp. 291-303
-
-
McMahon, M.1
Marsh, H.M.2
Rizza, R.A.3
-
7
-
-
0025066579
-
Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM
-
Mitrakou, A., D. Kelley, T. Veneman, T. Jenssen, T. Pangburn, J. Reilly, and J. Gerich. 1990. Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM. Diabetes. 39:1381-1390.
-
(1990)
Diabetes
, vol.39
, pp. 1381-1390
-
-
Mitrakou, A.1
Kelley, D.2
Veneman, T.3
Jenssen, T.4
Pangburn, T.5
Reilly, J.6
Gerich, J.7
-
8
-
-
0025966024
-
Contribution to postprandial hyperglycemia and effect on initial splanchnic glucose clearance of hepatic glucose cycling in glucose-intolerant or NIDDM patients
-
Butler, R.C., and R.A. Rizza. 1991. Contribution to postprandial hyperglycemia and effect on initial splanchnic glucose clearance of hepatic glucose cycling in glucose-intolerant or NIDDM patients. Diabetes. 40:73-81.
-
(1991)
Diabetes
, vol.40
, pp. 73-81
-
-
Butler, R.C.1
Rizza, R.A.2
-
9
-
-
0027967674
-
Impaired postprandial glucose utilization in non-insulin-dependent diabetes mellitus
-
Kelley, D., M. Mokan, and T. Veneman. 1994. Impaired postprandial glucose utilization in non-insulin-dependent diabetes mellitus. Metabolism. 43: 1549-1557.
-
(1994)
Metabolism
, vol.43
, pp. 1549-1557
-
-
Kelley, D.1
Mokan, M.2
Veneman, T.3
-
10
-
-
0014898491
-
Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes
-
Shen, S.W., G.M. Reaven, and J.W. Farquhar. 1970. Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J. Clin. Invest. 49:2151-2160.
-
(1970)
J. Clin. Invest.
, vol.49
, pp. 2151-2160
-
-
Shen, S.W.1
Reaven, G.M.2
Farquhar, J.W.3
-
11
-
-
0017670714
-
Glucose, insulin and somatostatin infusion for the determination of insulin sensitivity
-
Harano, Y., S. Ohgaku, H. Hidaka, K. Haneda, R. Kikkawa, Y. Shigeta, and H. Abe. 1977. Glucose, insulin and somatostatin infusion for the determination of insulin sensitivity. J. Clin. Endocrinol. & Metab. 45:1124-1127.
-
(1977)
J. Clin. Endocrinol. & Metab.
, vol.45
, pp. 1124-1127
-
-
Harano, Y.1
Ohgaku, S.2
Hidaka, H.3
Haneda, K.4
Kikkawa, R.5
Shigeta, Y.6
Abe, H.7
-
12
-
-
0018773348
-
Insulin sensitivity and insulin binding to monocytes in maturity-onset diabetes
-
DeFronzo, R., D. Deibert, R. Hendler, P. Felig, and V. Soman. 1979. Insulin sensitivity and insulin binding to monocytes in maturity-onset diabetes. J. Clin. Invest. 63:939-946.
-
(1979)
J. Clin. Invest.
, vol.63
, pp. 939-946
-
-
DeFronzo, R.1
Deibert, D.2
Hendler, R.3
Felig, P.4
Soman, V.5
-
13
-
-
0019415752
-
Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus
-
Kolterman, O.G., R.S. Gray, J. Griffin, P. Burstein, J. Insel, J.A. Scarlett, and J.M. Olefsky. 1981. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. J. Clin. Invest. 68:957-969.
-
(1981)
J. Clin. Invest.
, vol.68
, pp. 957-969
-
-
Kolterman, O.G.1
Gray, R.S.2
Griffin, J.3
Burstein, P.4
Insel, J.5
Scarlett, J.A.6
Olefsky, J.M.7
-
14
-
-
0019761497
-
Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus
-
Rizza, R.A., L.J. Mandarino, and J.E. Gerich. 1981. Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus. Diabetes. 30:990-995.
-
(1981)
Diabetes
, vol.30
, pp. 990-995
-
-
Rizza, R.A.1
Mandarino, L.J.2
Gerich, J.E.3
-
15
-
-
0017871767
-
Relationship between the plasma glucose level and glucose uptake in the conscious dog
-
Cherrington, A.D., P.E. Williams, and M.S. Harris. 1978. Relationship between the plasma glucose level and glucose uptake in the conscious dog. Metabolism. 27:787-791.
-
(1978)
Metabolism
, vol.27
, pp. 787-791
-
-
Cherrington, A.D.1
Williams, P.E.2
Harris, M.S.3
-
16
-
-
0018084372
-
Hyperglycemia inhibits glucose production in man independent of changes in glucoregulatory hormones
-
Sacca, L., R. Hendler, and R.S. Sherwin. 1978. Hyperglycemia inhibits glucose production in man independent of changes in glucoregulatory hormones. J. Clin. Endocrinol. & Metab. 47:1160-1161.
-
(1978)
J. Clin. Endocrinol. & Metab.
, vol.47
, pp. 1160-1161
-
-
Sacca, L.1
Hendler, R.2
Sherwin, R.S.3
-
17
-
-
0019447449
-
Glucose disposal is not proportional to plasma glucose level in man
-
Best, J.D., G.J. Taborsky, Jr., J.B. Halter, and D. Porte, Jr. 1981. Glucose disposal is not proportional to plasma glucose level in man. Diabetes. 30: 847-850.
-
(1981)
Diabetes
, vol.30
, pp. 847-850
-
-
Best, J.D.1
Taborsky Jr., G.J.2
Halter, J.B.3
Porte Jr., D.4
-
18
-
-
0021867605
-
Comparison of insulin-mediated and glucose-mediated glucose disposal in patients with insulin-dependent diabetes mellitus and in nondiabetic subjects
-
Hansen, I.L., P.E. Cryer, and R.A. Rizza. 1985. Comparison of insulin-mediated and glucose-mediated glucose disposal in patients with insulin-dependent diabetes mellitus and in nondiabetic subjects. Diabetes. 34:751-755.
-
(1985)
Diabetes
, vol.34
, pp. 751-755
-
-
Hansen, I.L.1
Cryer, P.E.2
Rizza, R.A.3
-
19
-
-
0022551871
-
Direct evidence for a stimulatory effect of hyperglycemia per se on peripheral glucose disposal in type II diabetes
-
Capaldo, B., D. Santoro, G. Riccardi, N. Perrotti, and L. Saccà. 1986. Direct evidence for a stimulatory effect of hyperglycemia per se on peripheral glucose disposal in type II diabetes. J. Clin. Invest. 77:1285-1290.
-
(1986)
J. Clin. Invest.
, vol.77
, pp. 1285-1290
-
-
Capaldo, B.1
Santoro, D.2
Riccardi, G.3
Perrotti, N.4
Saccà, L.5
-
20
-
-
0027999957
-
Assessment of insulin action and glucose effectiveness in diabetic and nondiabetic humans
-
Alzaid, A.A., S.F. Dinneen, D.J. Turk, A. Caumo, C. Cobelli, and R.A. Rizza. 1994. Assessment of insulin action and glucose effectiveness in diabetic and nondiabetic humans. J. Clin. Invest. 94:2341-2348.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 2341-2348
-
-
Alzaid, A.A.1
Dinneen, S.F.2
Turk, D.J.3
Caumo, A.4
Cobelli, C.5
Rizza, R.A.6
-
21
-
-
0027983920
-
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
-
Nolan, J.J., B. Ludvik, P. Beerdsen, M. Joyce, and J. Olefsky. 1994. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N. Engl. J. Med. 331:1188-1193.
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1188-1193
-
-
Nolan, J.J.1
Ludvik, B.2
Beerdsen, P.3
Joyce, M.4
Olefsky, J.5
-
22
-
-
0026596851
-
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus
-
Gutniak, M., C. Orskov, J.J. Holst, B. Ahren, and S. Efendic. 1992. Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N. Engl. J. Med. 326:1316-1322.
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 1316-1322
-
-
Gutniak, M.1
Orskov, C.2
Holst, J.J.3
Ahren, B.4
Efendic, S.5
-
23
-
-
0027972684
-
[Lys(B28), Pro(B29)]-human insulin. A rapidly absorbed analogue of human insulin
-
Howey, D.C., R.R. Bowsher, R.L. Brunelle, and J.R. Woodworth. 1994. [Lys(B28), Pro(B29)]-human insulin. A rapidly absorbed analogue of human insulin. Diabetes. 43:396-402.
-
(1994)
Diabetes
, vol.43
, pp. 396-402
-
-
Howey, D.C.1
Bowsher, R.R.2
Brunelle, R.L.3
Woodworth, J.R.4
-
24
-
-
0023836241
-
Incretin effect due to increased secretion and decreased clearance of insulin in normal humans
-
Shuster, L.T., V.L.W. Go, R.A. Rizza, P.C. O'Brien, and F.J. Service. 1988. Incretin effect due to increased secretion and decreased clearance of insulin in normal humans. Diabetes. 37:200-203.
-
(1988)
Diabetes
, vol.37
, pp. 200-203
-
-
Shuster, L.T.1
Go, V.L.W.2
Rizza, R.A.3
O'Brien, P.C.4
Service, F.J.5
-
25
-
-
0019950002
-
Practical closed-loop insulin delivery. A system for the maintenance of overnight euglycemia and the calculation of basal insulin requirements in insulin-dependent diabetics
-
White, N.H., D. Skor, and J.V. Santiago. 1982. Practical closed-loop insulin delivery. A system for the maintenance of overnight euglycemia and the calculation of basal insulin requirements in insulin-dependent diabetics. Ann. Intern. Med. 97:210-213.
-
(1982)
Ann. Intern. Med.
, vol.97
, pp. 210-213
-
-
White, N.H.1
Skor, D.2
Santiago, J.V.3
-
26
-
-
0028084848
-
Assessment of insulin action in NIDDM in the presence of dynamic changes in insulin and glucose concentration
-
Katz, H., M. Homan, M. Jensen, A. Caumo, C. Cobelli, and R. Rizza. 1994. Assessment of insulin action in NIDDM in the presence of dynamic changes in insulin and glucose concentration. Diabetes. 43:289-296.
-
(1994)
Diabetes
, vol.43
, pp. 289-296
-
-
Katz, H.1
Homan, M.2
Jensen, M.3
Caumo, A.4
Cobelli, C.5
Rizza, R.6
-
27
-
-
0027223164
-
Quantitation of measurement error with optimal segments: Basis for adaptive time course smoothing
-
Bradley, D.C., G.M. Steil, and R.N. Bergman. 1993. Quantitation of measurement error with optimal segments: basis for adaptive time course smoothing. Am. J. Physiol. 264:E902-911.
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Bradley, D.C.1
Steil, G.M.2
Bergman, R.N.3
-
28
-
-
77049274176
-
Measurement of size and turnover rate of body glucose pool by the isotope dilution method
-
Steele, R., J.S. Wall, R.C. De Bodo, N. Altszuler, S.P. Kiang, and C. Bjerknes. 1956. Measurement of size and turnover rate of body glucose pool by the isotope dilution method. Am. J. Physiol. 187:15-24.
-
(1956)
Am. J. Physiol.
, vol.187
, pp. 15-24
-
-
Steele, R.1
Wall, J.S.2
De Bodo, R.C.3
Altszuler, N.4
Kiang, S.P.5
Bjerknes, C.6
-
29
-
-
0011523940
-
Robust statistics for testing equality of means or variances
-
Tiku, M.L. 1982. Robust statistics for testing equality of means or variances. Communications in Statistics-Theory and Methods. 11:2543-2558.
-
(1982)
Communications in Statistics-Theory and Methods
, vol.11
, pp. 2543-2558
-
-
Tiku, M.L.1
-
31
-
-
0021912102
-
Impact of the "early peak" of insulin secretion on glucose utilization in man
-
Bratusch-Marrain, P.R., and W.K. Waldhäusl. 1985. Impact of the "early peak" of insulin secretion on glucose utilization in man. Horm. Metabol. Res. 17:163-164.
-
(1985)
Horm. Metabol. Res.
, vol.17
, pp. 163-164
-
-
Bratusch-Marrain, P.R.1
Waldhäusl, W.K.2
-
32
-
-
0024216182
-
Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes
-
Bruce, D.G., D.J. Chisholm, L.H. Storlien, and E.W. Kraegen. 1988. Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes. Diabetes. 37:736-744.
-
(1988)
Diabetes
, vol.37
, pp. 736-744
-
-
Bruce, D.G.1
Chisholm, D.J.2
Storlien, L.H.3
Kraegen, E.W.4
-
33
-
-
0024422762
-
Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans
-
Luzi, L., and R.A. DeFronzo. 1989. Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans. Am. J. Physiol. 257:E241-E246.
-
(1989)
Am. J. Physiol.
, vol.257
-
-
Luzi, L.1
DeFronzo, R.A.2
-
34
-
-
0023264686
-
Loss of early phase of insulin release in humans impairs glucose tolerance and blunts thermic effect of glucose
-
Calles-Escandon, J., and D.C. Robbins. 1987. Loss of early phase of insulin release in humans impairs glucose tolerance and blunts thermic effect of glucose. Diabetes. 36:1167-1172.
-
(1987)
Diabetes
, vol.36
, pp. 1167-1172
-
-
Calles-Escandon, J.1
Robbins, D.C.2
-
35
-
-
0018602014
-
Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
-
National Diabetes Data Group. 1979. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 28:1039-1057.
-
(1979)
Diabetes
, vol.28
, pp. 1039-1057
-
-
-
36
-
-
0025943822
-
Effects of pancreas transplantation on postprandial glucose metabolism
-
Katz, H., M. Homan, J. Velosa, P. Robertson, and R. Rizza. 1991. Effects of pancreas transplantation on postprandial glucose metabolism. N. Engl. J. Med. 325:1278-1283.
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 1278-1283
-
-
Katz, H.1
Homan, M.2
Velosa, J.3
Robertson, P.4
Rizza, R.5
-
37
-
-
0026443620
-
Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs
-
Giacca, A., S.J. Fisher, Z.Q. Shi, R. Gupta, H.L.A. Lickley, and M. Vranic. 1992. Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs. J. Clin. Invest. 90:1769-1777.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1769-1777
-
-
Giacca, A.1
Fisher, S.J.2
Shi, Z.Q.3
Gupta, R.4
Lickley, H.L.A.5
Vranic, M.6
-
38
-
-
0027526476
-
Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo
-
Bradley, D.C., R.A. Poulin, and R.N. Bergman. 1993. Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo. Diabetes. 42:296-306.
-
(1993)
Diabetes
, vol.42
, pp. 296-306
-
-
Bradley, D.C.1
Poulin, R.A.2
Bergman, R.N.3
-
39
-
-
0021343484
-
Transhepatic glucagon gradients in man: Evidence for glucagon extraction by human liver
-
Jaspan, J.B., J. Ruddick, and E. Rayfield. 1984. Transhepatic glucagon gradients in man: evidence for glucagon extraction by human liver. J. Clin. Endocrinol. & Metab. 58:287-292.
-
(1984)
J. Clin. Endocrinol. & Metab.
, vol.58
, pp. 287-292
-
-
Jaspan, J.B.1
Ruddick, J.2
Rayfield, E.3
-
40
-
-
0016040157
-
Portal and peripheral vein immunoreactive glucagon concentrations after arginine or glucose infusions
-
Blackard, W.G., N.C. Nelson, and S.S. Andrews. 1974. Portal and peripheral vein immunoreactive glucagon concentrations after arginine or glucose infusions. Diabetes. 23:199-202.
-
(1974)
Diabetes
, vol.23
, pp. 199-202
-
-
Blackard, W.G.1
Nelson, N.C.2
Andrews, S.S.3
-
41
-
-
0017684132
-
The role of the liver in glucagon metabolism
-
Jaspan, J.B., A.H. Huen, C.G. Morley, A.R. Moossa, and A.H. Rubenstein. 1977. The role of the liver in glucagon metabolism. J. Clin. Invest. 60:421-428.
-
(1977)
J. Clin. Invest.
, vol.60
, pp. 421-428
-
-
Jaspan, J.B.1
Huen, A.H.2
Morley, C.G.3
Moossa, A.R.4
Rubenstein, A.H.5
-
42
-
-
0019542722
-
Hepatic metabolism of glucagon in the dog: Contribution of the liver to overall metabolic disposal of glucagon
-
Jaspan, J.B., K.S. Polonsky, M. Lewis, J. Pensler, W. Pugh, A.R. Moossa, and A.H. Rubenstein. 1981. Hepatic metabolism of glucagon in the dog: contribution of the liver to overall metabolic disposal of glucagon. Am. J. Physiol. 240:E233-E244.
-
(1981)
Am. J. Physiol.
, vol.240
-
-
Jaspan, J.B.1
Polonsky, K.S.2
Lewis, M.3
Pensler, J.4
Pugh, W.5
Moossa, A.R.6
Rubenstein, A.H.7
-
43
-
-
0028883204
-
Failure of glucagon suppression contributes to postprandial hyperglycemia in IDDM
-
Dinneen, S., A. Alzaid, D. Turk, and R. Rizza. 1995. Failure of glucagon suppression contributes to postprandial hyperglycemia in IDDM. Diabetologia. 38:337-343.
-
(1995)
Diabetologia
, vol.38
, pp. 337-343
-
-
Dinneen, S.1
Alzaid, A.2
Turk, D.3
Rizza, R.4
-
44
-
-
0019479354
-
Effects of somatostatin on gastrointestinal propagation and absorption of oral glucose in man
-
Johansson, C., O. Wisen, S. Efendic, and K. Uvnuäs-Wallensten. 1981. Effects of somatostatin on gastrointestinal propagation and absorption of oral glucose in man. Digestion. 22:126-137.
-
(1981)
Digestion
, vol.22
, pp. 126-137
-
-
Johansson, C.1
Wisen, O.2
Efendic, S.3
Uvnuäs-Wallensten, K.4
-
45
-
-
0021873259
-
14C labeled substrates
-
14C labeled substrates. Am. J. Physiol. 17:391-399.
-
(1985)
Am. J. Physiol.
, vol.17
, pp. 391-399
-
-
Katz, J.1
-
46
-
-
0020078617
-
Pathways of carbon flux in gluconeogenesis
-
Brosnan, J.T. 1982. Pathways of carbon flux in gluconeogenesis. Fed. Proc. 41:91-94.
-
(1982)
Fed. Proc.
, vol.41
, pp. 91-94
-
-
Brosnan, J.T.1
-
47
-
-
0023227752
-
Use of variable insulin infusion to assess insulin action in obesity: Defects in both the kinetics and amplitude of response
-
Doeden, B., and R. Rizza. 1987. Use of variable insulin infusion to assess insulin action in obesity: defects in both the kinetics and amplitude of response. J. Clin. Endocrinol. & Metab. 64:902-908.
-
(1987)
J. Clin. Endocrinol. & Metab.
, vol.64
, pp. 902-908
-
-
Doeden, B.1
Rizza, R.2
|