No influence of the endothelin receptor antagonist bosentan on basal and indomethacin-induced reduction of cerebral blood flow in pigs

Acta Anaesthesiologica Scandinavica

Volumn 47, Issue 2, 2003, Pages 200-207

  Rasmussen, Mads ^a   Poulsen, P H ^a   Treiber, A ^c   Delahaye, S ^c   Tankisi, A ^a   Cold, G E ^a   Therkelsen, K ^b   Gjedde, A ^a   Astrup, J ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

^c ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

Bosentan; Cerebral blood flow; Cerebral metabolic rate of oxygen; Endothelin; Indomethacin; Positron emission tomography

Indexed keywords

BOSENTAN; DRUG METABOLITE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; FENTANYL; INDOMETACIN; KETAMINE; MIDAZOLAM; NITROUS OXIDE; PANCURONIUM; PLACEBO; RO 48 5033; UNCLASSIFIED DRUG;

ANESTHESIA; ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; FEMALE; NONHUMAN; OXYGEN CONSUMPTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SWINE; VASOCONSTRICTION;

ANESTHESIA; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIHYPERTENSIVE AGENTS; BRAIN; BRAIN CHEMISTRY; CEREBROVASCULAR CIRCULATION; DRUG INTERACTIONS; FEMALE; INDOMETHACIN; OXYGEN CONSUMPTION; RECEPTORS, ENDOTHELIN; SULFONAMIDES; SWINE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 12244293415     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.2003.00019.x     Document Type: Article

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