Characterization of the pulmonary arterial response to endothelin-1 and bosentan in neonatal pigs

Annals of Thoracic Surgery

Volumn 70, Issue 5, 2000, Pages 1522-1530

  Domkowski, Patrick W ^a   Cockerham, John T ^a   Kot, Peter A ^a   Myers, Jeff L ^a   Hopkins, Richard A ^a,b  

^a BROWN UNIVERSITY   (United States)

^b Cardiothoracic Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOSENTAN; ENDOTHELIN 1;

ANIMAL EXPERIMENT; BLOOD VESSEL REACTIVITY; CONFERENCE PAPER; FEMALE; IMPEDANCE; LUNG VASCULAR RESISTANCE; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; SWINE; VASOCONSTRICTION; YOUNG MODULUS;

ANIMALS; ANIMALS, NEWBORN; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; ENDOTHELIN-1; FEMALE; MALE; MODELS, ANIMAL; PULMONARY ARTERY; RANDOM ALLOCATION; RECEPTORS, ENDOTHELIN; SULFONAMIDES; SWINE; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 0033767485     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(00)01820-8     Document Type: Conference Paper

References (24)

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
2. The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
3. Cloning and expression of a cDNA encoding an endothelin receptor
4. Endothelin-1 has a dilator effect on neonatal pig pulmonary vasculature
5. Maturational changes in endothelium-derived relaxations in newborn piglet pulmonary circulation
6. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
7. Endothelin peptides: Biological action and pathophysiological significance in the lung
8. Functional evidence of different endothelin receptors in the lung
9. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor
10. Interaction among ET-1, endothelium-derived nitric oxide and prostacyclin in pulmonary arteries and veins
11. International union of pharmacology nomenclature of endothelin receptors
12. Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist
13. In vivo pharmacology of Ro 46-2005, the first synthetic nonpeptide endothelin receptor antagonist: Implications for endothelin physiology
14. Pulmonary hydraulic impedance response to hypoxia and hypercapnia in newborn pigs
15. Pulmonary hydraulic impedance response to cromakalim in newborn pigs
16. In vivo validation of the transit-time ultrasonic volume flow meter
17. Circulatory effects of endothelin in newborn piglets
18. Endothelin(B) receptor agonist produce vasodilation in intact newborn lambs with pulmonary hypertension
19. BQ123, an ET(A) receptor antagonist, attenuated endothelin-1 induced vasoconstriction in rat pulmonary circulation
20. The role of endothelin and endothelin receptor subtypes in regulation of fetal pulmonary vascular tone
21. Pulmonary vascular input impedance in the newborn and infant pig
22. An analysis of the pulsatile hemodynamic responses of the pulmonary circulation to acute and chronic pulmonary venous hypertension in the awake dog
23. Changes in the distensibility of the intrapulmonary arteries in the normal newborn and growing pig
24. Recent advances in the treatment of pediatric pulmonary artery hypertension