The microenvironment of AFT024 cells maintains primitive human hematopoiesis by counteracting contact mediated inhibition of proliferation

Cell Communication and Adhesion

Volumn 9, Issue 3, 2002, Pages 149-159

  Punzel, Michael ^a   Gupta, Pankaj ^b   Verfaillie, Catherine M ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

AFT024; Human hematopoietic stems cells; O sulfated heparane sulfate glycosaminoglycans; Proliferation inhibition

Indexed keywords

CYTOKINE; INTERLEUKIN 3; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROTEOHEPARAN SULFATE;

ANIMAL CELL; CELL ADHESION; CELL CONTACT; CELL CULTURE; CELL CYCLE; CELL GROWTH; CELL LINE; CELL METABOLISM; CELL PROLIFERATION; CELL VIABILITY; CONTACT INHIBITION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXTRACELLULAR MATRIX; FETUS; FETUS CELL; GROWTH INHIBITION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HYPOTHESIS; LIVER CELL; MICROENVIRONMENT; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTE; REVIEW; STEM CELL;

ANIMALIA; MURINAE;

EID: 12244263452     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.1080/15419060214521     Document Type: Review

References (43)

1. Itoh K, Tezuka H, Sakoda H, Konno M, Nagata K, Uchiyama T, Uchino H, Mori KJ (1989). Reproducible establishment of hematopoietic supportive stromal cell lines from murine bone marrow. Exp Hematol 17: 145-153.
2. Issaad C, Croisille L, Katz A, Vainchenker W, Coulombel L (1993). A murine stromal cell line allows proliferation of very primitive human CD34++/38- progenitor cells in long-term cultures and semisolid assays. Blood 81: 2916-2924.
3. Berardi AC, Meffre E, Pflumio F, Katz A, Vainchenker W, Schiff C, Coulombel L (1997). Individual CD34+/CD38low/CD19-/CD10- progenitor cells from human cord blood generate B lymphocytes and granulocytes. Blood 89: 3554-3564.
4. Sutherland HJ, Eaves CJ, Landsdorp PM, Thacker JD, Hogge DE (1991). Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood 78: 666-672.
5. Burroughs JM, Gupta P, Verfaillie CM (1994). Soluble factors from the mouse fibroblast cell line M2-10B4 support in vitro hematopoiesis. Exp Hematol 22: 1095-1101.
6. Baum CM, Weissman IL, Tsukamoto AS, Buckle AM, Peault B (1992). Isolation of a candidate human hematopoietic stem-cell population. Proc Natl Acad Sci USA 89: 2804-2808.
7. Murray L, DiGiusto D, Chen B, Chen S, Combs J, Conti A, Galy A, Negrin R, Tricot G, Tsukamoto A (1994). Analysis of human stem cell populations. Blood Cells 20: 364-370.
8. Young JC, Bruno E, Luens KM, Wu S, Backer M, Murray LJ (1996). Thrombopoietin stimulates megakaryocytopoiesis, myelopoiesis, and expansion of CD34+ progenitor cells from single CD34+/Thy-1+/Lin- primitive progenitor cells. Blood 88: 1619-1631.
9. Rawlings DJ, Quan SG, Kato RM, Witte ON (1995). Long-term culture system for selective growth of human B-cell progenitors. Proc Natl Acad Sci USA 92: 1570-1574.
10. Rawlings DJ, Quan S, Hao QL, Thiemann FT, Smogorzewska M, Witte ON, Crooks GM (1997). Differentiation of human CD34+ CD38- cord blood stem cells into B cell progenitors in vitro. Exp Hematol 25: 66-72.
11. Hao QL, Smogorzewska EM, Barsky LW, Crooks GM (1998). In vitro identification of single CD34+/CD38- cells with both lymphoid and myeloid potential. Blood 91: 4145-4151.
12. Breems DA, Blokland EAW, Neben S, Ploemacher RE (1994). Frequency analysis of human primitive hematopoietic stem cell subsets using a cobblestone area forming cell assay. Leukemia 8: 1095-1104.
13. Moore KA, Hideo E, Lemischka IR (1997). In vitro maintenance of highly purified, transplantable hematopoietic stem cells. Blood 89: 4337-4347.
14. Thiemann FT, Moore KA, Smogorzewska EM, Lemischka IR, Crooks GM (1998). The murine stromal cell line AFT024 acts specifically on human CD34+CD38- progenitors to maintain primitive function and immunophenotype in vitro. Exp Hematol 26: 612-619.
15. Punzel M, Gupta P, Roodell M, Mortari F, Verfaillie CM (1999). Factor(s) secreted by AFT024 fetal liver cells following stimulation with human cytokines are important for human LTC-IC growth. Leukemia 13: 1079-1084.
16. Punzel M, Wissink SD, Miller JS, Moore KA, Lemischka IR, Verfaillie CM (1999). The myeloid-lymphoid initiating cell (ML-IC) assay assesses the fate of multipotent human progenitors in vitro. Blood 93: 3750-3756.
17. Punzel M, Moore KA, Lemischka IR, Verfaillie CM (1999). The type of stromal feeder used in limiting dilution assays influences frequency and maintenance assessment of human long-term culture initiating cells. Leukemia 13: 92-97.
18. Miller JS, McCullar V, Punzel M, Lemischka IR, Moore KA (1999). Single adult human CD34(+)/Lin-/CD38(-) progenitors give rise to natural killercells, B-lineage cells, dendritic: cells, and myeloid cells. Blood 93: 96-106.
19. Verfaillie CM, Catanzarro PM (1996). Direct contact with stroma inhibits proliferation of long-term culture initiating cells. Leukemia 10: 498-504.
20. Hurley RW, McCarthy JB, Verfaillie CM (1995). Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest 96: 5111-5119.
21. Verfaillie CM (1992). Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis. Blood 79: 2821-2826.
22. Jiang Y, Zhao RC, Verfaillie CM (2000). Abnormal integrin-mediated regulation of chronic myelogenous leukemia CD34+ cell proliferation: BCR/ABL up-regulates the cyclin-dependent kinase inhibitor, p27Kip, which is relocated to the cell cytoplasm and incapable of regulating cdk2 activity. Proc Natl Acad Sci USA 97: 10538-10543.
23. Jiang Y, Prosper F, Verfaillie CM (1999). Opposing effects of engagement of integrins and stimulation of cytokinereceptors on cell cycle progression of normal human hematopoietic progenitors. Blood 95: 846-854.
24. Gupta P, McCarthy JB, Verfaillie CM (1996). Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells. Blood 87: 3229-3236.
25. Gupta P, Oegema TR, Brazil JJ, Dudek AZ, Slungaard A, Verfaillie CM (1998). Structurally specific heparan sulfate support primitive human hematopoiesis by formation of a multimolecular stem cell niche. Blood 92: 4641-4651.
26. Gupta P, Oegema TR, Brazil JJ, Dudek AZ, Slungaard A, Verfaillie CM (2000). Human LTC-IC can be maintained for at least 5 weeks in vitro when interleukin-3 and a single chemokine are combined with O-sulfated heparan sulfates: Requirement for optimal binding interactions of heparan sulfate with early-acting cytokines and matrix proteins. Blood 95: 147-155.
27. Miller JS, Oelkers S, Verfaillie CM, McGlave PB (1992). Role of Monocytes in the expansion of human activated natural killer cells. Blood 80: 2221-2229.
28. Wasteson A (1971). A method for the determination of the molecular weight and molecular weight distribution of chondroitin sulfate. J Chromatogr 59: 87-97.
29. Conrad GW, Hamilton C, Haynes E (1977). Differences in glycosaminoglycans synthesized by fibroblast-like cells from chick cornea, heart and skin. J Biol Chem 252: 6861-6870.
30. Trescony PV, Oegema TR, Farnam BJ, Deloria LB (1989). Analysis of heparan sulfate from the Engelbreth-Holm-Swarm (EHS) tumor. Connect Tissue Res 19: 219-242.
31. Verfaillie CM, Catanzarro PM, Li WM (1994). Macrophage inflammatory protein-1α, Interleukin-3 and diffusible marrow stromal factors maintain human hematopoietic stem cells for at least eight weeks in vitro. J Exp Med 179: 643-649.
32. Verfaillie CM, Miller JS (1995). A novel single cell proliferation assay demonstrates that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC. Blood 86: 2137-2145.
33. Gupta P, Blazar BR, Gupta K, Verfaillie CM (1998). Human CD34(+) bone marrow cells regulate stromal production of interleukin-6 and granulocyte colony-stimulating factor and increase the colony-stimulating activity of stroma. Blood 91: 3724-3733.
34. Moore KA, Pytowski B, Witte L, Hickling D, Lemischka IR (1997). Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs. Proc Natl Acad Sci USA 94: 4011-4016.
35. Moore KA, Lemischka IR (1998). Defining the stem cell niche in the hematopoietic microenvironment. Blood 92: 1971 (abstract).
36. Moore KA, Lemischka IR (2000). The molecular profile of AFT024, a stem cell supporting stromal cell line. Blood 96: 2448 (abstract).
37. Han W, Ye Q, Moore MA (2000). A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells. Blood 9: 1616-1625.
38. Drzeniek Z, Siebertz B, Stocker G, Just U, Ostertag W, Greiling H, Haubeck HD (1997). Proteoglycan synthesis in haematopoietic cells: Isolation and characterization of heparan sulphate proteoglycans expressed by the bone-marrow stromal cell line MS-5. Biochem J 327: 473-480.
39. Kaji T, Yamada A, Miyajima S, Yamamoto C, Fujiwara Y, Wright TN, Kinsella MG (2000). Cell density dependent regulation of proteoglycan synthesis by transforming groth factor beta (1) in cultured bovine aortic endothelial cells. J Biol Chem 275: 1463-1470.
40. Brown CT, Nugent MA, Lau FW, Randall-Trinkaus V (1999). Characterizations of proteoglycans synthesized by cultured corneal fibroblasts in response to transforming growth factor and fetal calf serum. J Biol Chem 274: 7111-7119.
41. Wegrowski Y, Paltot V, Gillery P, Kalis B, Randoux A, Marquart FX (1995). Stimulation of sulfated glycosaminoglycan and decorin production in adult dermal fibroblasts by recombinant human interleukin-4. Biochem J 307: 673-678.
42. Maiti A, Maki G, Johnson P (1998). TNF-alpha production of CD44-mediated leukocyte adhesion by sulfation. Science 282: 941-943.
43. Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K, Pietrzkowski Z, Kowalska M, Gewirtz A, Emerson S, Ratajczak M (2001). Numerous growth factors, cytokines and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 97: 3075-3085.