Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells

Blood

Volumn 87, Issue 8, 1996, Pages 3229-3236

  Gupta, Pankaj ^a   McCarthy, James B ^a   Verfaillie, Catherine M ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIV OF MINNESOTA HOSP AND CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE;

ARTICLE; CELL CLONE; CELL CULTURE; CELL DIFFERENTIATION; CLONOGENESIS; FIBROBLAST; GEL FILTRATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STROMA CELL;

EID: 0029915836     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.8.3229.bloodjournal8783229     Document Type: Article

References (44)

1. Dexter TM, Coutinho LH, Spooncer E, Hey worth CM, Daniel CP, Schiro R, Chang J, Allen TD: Stromal cells in hematopoiesis. Ciba Found Symp 148:76, 1990
2. Sutherland HJ, Eaves CJ, Eaves AC, Dragowska W, Lansdorp PM: Characterization and partial purification of human marrow cells capable of initiating long term hematopoiesis in vitro. Blood 74:1563, 1989
3. Sutherland HJ, Eaves CJ, Lansdorp PM, Thacker JD, Hogge DE: Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood 78:666, 1991
4. Verfaillie CM: Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis. Blood 79:2821, 1992
5. Verfaillie CM: Soluble factor(s) produced by human bone marrow stroma increase cytokine-induced proliferation and maturation of primitive hematopoietic progenitors while preventing their terminal differentiation. Blood 82:2045, 1993
6. Verfaillie CM, Catanzarro PM, Li W: Macrophage inflammatory protein 1α, interleukin 3 and diffusible marrow stromal factors maintain human hematopoietic stem cells for at least eight weeks in vitro. J Exp Med 179:643, 1994
7. Burroughs J, Gupta P, Blazar B, Verfaillie CM: Diffusible factors from the murine cell Une M2-10B4 support human in vitro hematopoiesis. Exp Hematol 22:1095, 1994
8. Gupta P, Verfaillie CM: Soluble factors derived from human hematopoietic progenitors and precursors regulate cytokme production by human bone marrow stroma. Clin Res 41:644a, 1993 (abstr)
9. + cells into the myeloid lineage. Blood 80:1405, 1992
10. - progenitor cells. Blood 77:1218, 1991
11. Verfaillie CM, Miller JS: A novel single-cell proliferation assay shows that long-term culture-initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC. Blood 86:2137, 1995
12. Spooncer E, Gallagher JT, Krizsa F, Dexter TM: Regulation of haemopoiesis in long-term bone marrow cultures. IV. Glycosaminoglycan synthesis and the stimulation of haemopoiesis by b-D-xylosides. J Cell Biol 96:510, 1983
13. Roberts R, Gallagher J, Spooncer E, Allen TD, Bloomfield P, Dexter TM: Heparan sulfate bound growth factors: A mechanism for stromal cell mediated haemopoiesis. Nature 332:376, 1988
14. Bruno E, Luikart SD, Dixit V, Long MW, Hoffman R: Heparan sulfate proteoglycans (HS-PG) modulates the adhesion of pluripotent hematopoietic stem cells to cytokines. Exp Hematol 21:1025, 1993 (abstr)
15. Long MW, Bridcll R, Walter AW, Bruno E, Hoffman R: Human hematopoietic stem cell adherence to cytokines and matrix molecules J Clin Invest 90:251, 1992
16. Luikart SD, Maniglia CA, Furcht JT, McCarthy JB, Oegema Jr TR: A heparan sulfate-containing fraction of bone marrow stroma induces maturation of HL-60 cells in vitro. Cancer Res 50:3781, 1990
17. Hurley RW, McCarthy JB, Verfaillie CM: Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest 96:511, 1995
18. Gallagher JT, Spooncer E, Dexter TM: Role of the cellular matrix in haemopoiesis: I. Synthesis of glycosaminoglycans by mouse bone marrow cell cultures. J Cell Sci 63:155, 1983
19. Gordon MY, Riley GP, Watt SM, Greaves MF: Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment. Nature 326:403, 1987
20. Morris AJ, Dexter TM, Gallagher JT: Metabolic properties of a homogeneous proteoglycan of a haemopoietic stem cell line, FDCP-mix. Biochem J 260:479, 1989
21. Morris AJ, Turnbull JE, Riley GP, Gordon MY, Gallagher JT: Production of heparan sulphate proteoglycans by human bone marrow stromal cells. J Cell Sci 99:149, 1991
22. Wight TN, Kinsella MG, Keating A, Singer JW: Proteoglycans in human long-term bone marrow cultures: Biochemical and ultrastructural analyses. Blood 67:1333, 1986
23. Gallagher JT, Lyon M, Steward WP: Structure and function of heparan sulfate proteoglycans. Biochem J 236:313, 1986
24. Nurcombe V, Ford MD, Wildschut JA, Bartlett PF: Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan. Science 260:103, 1993
25. Maccarana M, Casu B, Lindahl U: Minimal sequence in heparin/heparan sulfate required for binding of basic FGF. J Biol Chem 268:23898, 1993
26. Fedarko NS, Ishihara M, Conrad HE: Control of cell division in hepatoma cells by exogenous heparan sulfate proteoglycan. J Cell Physiol 139:287, 1989
27. Wight TN, Kinsella MG, Qwarnstrom EE: The role of proteoglycans in cell adhesion, migration and proliferation. Curr Opin Cell Biol 4:793, 1992
28. Siczkowski M, Clarke D, Gordon MY: Binding of primitive hematopoietic progenitor cells to marrow stromal cells involves heparan sulfate. Blood 80:912, 1992
29. Han ZC, Wan HY, Bellucci S, Shen ZX, Maffrand JP, Pascal M, Petitou M, Lormeau JC, Caen JP: Glycosaminoglycans stimulate megakaryocytopoiesis in vitro and in vivo. Exp Hematol 21:1016, 1993 (abstr)
30. Graham GJ, Wright EG, Hewick R, Wolpe SD, Wilkie NM, Donaldson D, Lorimore S, Pragnell IB: Identification and characterization of an inhibitor of haematopoietic stem cell proliferation. Nature 344:442, 1990
31. Yamaguchi Y, Mann DM, Ruoslahti E: Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature 346:281, 1990
32. Brunner G, Gabrilove J, Rifkin DB, Wilson ET: Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan. J Cell Biol 114:1275, 1991
33. Ornitz DM, Herr AB, Nilsson M, Westman J, Svahn CM, Waksman G: FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. Science 268:432, 1995
34. McCarthy JB, Chelberg MK, Mickelson DJ, Furcht LT: Localization and chemical synthesis of flbronectin peptides with melanoma adhesion and heparin binding activities. Biochem 27:1380, 1988
35. Verfaillie C, Blakolmer K, McGlave P: Purified primitive human hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma. J Exp Med 172:509, 1990
36. Verfaillie CM, Benis A, Iida G, McGlave PB, McCarthy JB: Adhesion of committed human hematopoietic progenitors to synthetic peptides from the C-terminal heparin-binding domain of ribronectin: Cooperation between the integrin a4b1 and the CD44 adhesion receptor. Blood 84:1802, 1994
37. Trescony PV, Oegema TR, Famam BJ, Deloria LB: Analysis of heparan sulfate from the Engelbreth-Holm-Swarm (EHS) tumor. Connect Tissue Res 19:219, 1989
38. Brown DM, Michael AF, Oegema TR: Glycosaminoglycan synthesis by glomeruli in vivo and in vitro. Biochim Biophys Acta 674:96, 1981
39. Conrad GW, Hamilton C, Hayes E: Differences in glycosaminoglycans synthesized by fibroblast-like cells from chick cornea, heart and skin. J Biol Chem 252:6861, 1977
40. McDevitt CA, Muir H: Gel electrophoresis of proteoglycans and glycosaminoglycans on large-pore composite polyacrylamideagarose gels. Anal Biochem 44:612, 1971
41. Price LKH, Choi HU, Rosenberg L, Stanley ER: The predominant form of secreted colony stimulating factor-1 is a proteoglycan. J Biol Chem 267:2190, 1992
42. Lowry PA, Deacon D, Whitefield P, McGrath HE, Quesenberry PJ: Stem cell factor induction of in vitro murine hematopoietic colony formation by "subliminal" cytokine combinations: The role of "anchor factors". Blood 80:663, 1992
43. Prestrelski SJ, Fox FM, Arakawa T: Binding of heparin to basic fibroblast growth factor induces a conformational change. Arch Biochem Biophys 293:314, 1992
44. Omitz DM, Yayon A, Flanagan JG, Svahn CM, Levi E, Leder P: Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol Cell Biol 12:240, 1992