-
1
-
-
0002917945
-
Epidemiologic trends
-
Barnes PJ, Grunstein MM, Leff AR, Woolcock AJ, eds. Philadelphia, PA: Lippincott Raven
-
Burney PGJ. Epidemiologic trends. In: Barnes PJ, Grunstein MM, Leff AR, Woolcock AJ, eds. Asthma. Philadelphia, PA: Lippincott Raven; 1997:35-47.
-
(1997)
Asthma
, pp. 35-47
-
-
Burney, P.G.J.1
-
3
-
-
0033604599
-
Therapeutic strategies for allergic diseases
-
Barnes PJ. Therapeutic strategies for allergic diseases. Nature. 1999;402:B31-B37.
-
(1999)
Nature
, vol.402
-
-
Barnes, P.J.1
-
4
-
-
1542278045
-
The need for new therapy
-
Hansel TT, Barnes PJ, eds. Basel, Switzerland: Karger
-
Barnes PJ, Hansel TT. The need for new therapy. In: Hansel TT, Barnes PJ, eds. New drugs for asthma, allergy and COPD. Basel, Switzerland: Karger;2001:2-5.
-
(2001)
New Drugs for Asthma, Allergy and COPD
, pp. 2-5
-
-
Barnes, P.J.1
Hansel, T.T.2
-
5
-
-
0000842911
-
Protein C
-
High KA, Robert HR, eds. Tokyo: Marcel Dekker
-
Suzuki K. Protein C. In: High KA, Robert HR, eds. Molecular Basis of Thrombosis and Hemostasis. Tokyo: Marcel Dekker; 1995:395-423.
-
(1995)
Molecular Basis of Thrombosis and Hemostasis
, pp. 395-423
-
-
Suzuki, K.1
-
6
-
-
0032845209
-
Regulation and functions of the protein C anticoagulant pathway
-
Esmon CT, Gu JM, Xu J, Qu D, Stearns-Kurosawa DJ, Kurosawa S. Regulation and functions of the protein C anticoagulant pathway. Haematologica. 1999;84:363-368.
-
(1999)
Haematologica
, vol.84
, pp. 363-368
-
-
Esmon, C.T.1
Gu, J.M.2
Xu, J.3
Qu, D.4
Stearns-Kurosawa, D.J.5
Kurosawa, S.6
-
7
-
-
0031861489
-
Protein C anticoagulant system in patients with interstitial lung disease
-
Kobayashi H, Gabazza EC, Taguchi O, et al. Protein C anticoagulant system in patients with interstitial lung disease. Am J Respir Crit Care Med. 1998;157:1850-1854.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1850-1854
-
-
Kobayashi, H.1
Gabazza, E.C.2
Taguchi, O.3
-
8
-
-
20244382519
-
Decreased protein C activation is associated with abnormal collagen turnover in the intraalveolar space of patients with interstitial lung disease
-
Yasui H, Gabazza EC, Taguchi O, et al. Decreased protein C activation is associated with abnormal collagen turnover in the intraalveolar space of patients with interstitial lung disease. Clin Appl Thromb Hemost. 2000;6:202-205.
-
(2000)
Clin Appl Thromb Hemost
, vol.6
, pp. 202-205
-
-
Yasui, H.1
Gabazza, E.C.2
Taguchi, O.3
-
9
-
-
0036905914
-
Activation of protein C pathway in the airways
-
Hataji O, Taguchi O, Gabazza EC, Yuda H, Suzuki K, Adachi Y. Activation of protein C pathway in the airways. Lung. 2002;180:47-59.
-
(2002)
Lung
, vol.180
, pp. 47-59
-
-
Hataji, O.1
Taguchi, O.2
Gabazza, E.C.3
Yuda, H.4
Suzuki, K.5
Adachi, Y.6
-
10
-
-
0034955797
-
Intratracheal administration of activated protein c inhibits bleomycin-induced lung fibrosis in the mouse
-
Yasui H, Gabazza EC, Tamaki S, et al. Intratracheal administration of activated protein c inhibits bleomycin-induced lung fibrosis in the mouse. Am J Respir Crit Care Med. 2001;163:1660-1668.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1660-1668
-
-
Yasui, H.1
Gabazza, E.C.2
Tamaki, S.3
-
11
-
-
0037086296
-
Bleomycin-induced lung fibrosis: The authors should have used another method to induce pulmonary lesions resembling human idiopathic pulmonary fibrosis
-
Gabazza EC, Taguchi O, Adachi Y. Bleomycin-induced lung fibrosis: the authors should have used another method to induce pulmonary lesions resembling human idiopathic pulmonary fibrosis [letter]. Am J Respir Crit Care Med. 2002;165:845-846.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 845-846
-
-
Gabazza, E.C.1
Taguchi, O.2
Adachi, Y.3
-
12
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001;344:699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
13
-
-
0034019454
-
Role of activated protein C in Helicobacter pylori-associated gastritis
-
Oka S, Gabazza EC, Taguchi Y, et al. Role of activated protein C in Helicobacter pylori-associated gastritis. Infect Immun. 2000;68:2863-2869.
-
(2000)
Infect Immun
, vol.68
, pp. 2863-2869
-
-
Oka, S.1
Gabazza, E.C.2
Taguchi, Y.3
-
14
-
-
0038290189
-
Activated protein C inhibits the expression of platelet-derived growth factor in the lung
-
Shimizu S, Gabazza EC, Taguchi O, et al. Activated protein C inhibits the expression of platelet-derived growth factor in the lung. Am J Respir Crit Care Med. 2003;167:1416-1426.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1416-1426
-
-
Shimizu, S.1
Gabazza, E.C.2
Taguchi, O.3
-
15
-
-
0035815747
-
Gene expression profile of antithrombotic protein C defines new mechanism modulating inflammation and apoptosis
-
Joyce DE, Gelbert L, Ciaccia A, DeHoff B, Grinnell BW. Gene expression profile of antithrombotic protein C defines new mechanism modulating inflammation and apoptosis. J Biol Chem. 2001;276:11199-11203.
-
(2001)
J Biol Chem
, vol.276
, pp. 11199-11203
-
-
Joyce, D.E.1
Gelbert, L.2
Ciaccia, A.3
DeHoff, B.4
Grinnell, B.W.5
-
16
-
-
0028925756
-
Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR)
-
Fukudome K, Esmon CT. Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). J Biol Chem. 1995;270:5571-5577.
-
(1995)
J Biol Chem
, vol.270
, pp. 5571-5577
-
-
Fukudome, K.1
Esmon, C.T.2
-
17
-
-
0032742158
-
Endothelial protein C receptor
-
Esmon CT, Xu J, Gu JM, et al. Endothelial protein C receptor. Thromb Haemost. 1999;82:251-258.
-
(1999)
Thromb Haemost
, vol.82
, pp. 251-258
-
-
Esmon, C.T.1
Xu, J.2
Gu, J.M.3
-
18
-
-
0031781163
-
An improved murine model of asthma: Selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerolised allergen
-
Temelkovski J, Hogan SP, Shepherd DP, Foster PS, Kumar RK. An improved murine model of asthma: selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerolised allergen. Thorax. 1998;53:849-856.
-
(1998)
Thorax
, vol.53
, pp. 849-856
-
-
Temelkovski, J.1
Hogan, S.P.2
Shepherd, D.P.3
Foster, P.S.4
Kumar, R.K.5
-
19
-
-
0030800586
-
Non-invasive measurement of airway responsiveness in allergic mice using barometric plethysmography
-
Hamelmann E, Schwarze J, Takeda K, et al. Non-invasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med. 1997;156:766-775.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 766-775
-
-
Hamelmann, E.1
Schwarze, J.2
Takeda, K.3
-
20
-
-
0029808482
-
Intracellular demonstration of active TGFbeta1 in B cells and plasma cells of autoimmune mice. IgG-bound TGFbeta1 suppresses neutrophil function and host defense against Staphylococcus aureus infection
-
Caver TE, O'Sullivan FX, Gold LI, Gresham HD. Intracellular demonstration of active TGFbeta1 in B cells and plasma cells of autoimmune mice. IgG-bound TGFbeta1 suppresses neutrophil function and host defense against Staphylococcus aureus infection. J Clin Invest. 1996;8:2496-2506.
-
(1996)
J Clin Invest
, vol.8
, pp. 2496-2506
-
-
Caver, T.E.1
O'Sullivan, F.X.2
Gold, L.I.3
Gresham, H.D.4
-
21
-
-
0032951303
-
Acetylcholine-induced endothelium-derived contracting factor in hypoxic pulmonary hypertensive rats
-
Maruyama J, Yokochi A, Maruyama K, Nosaka S. Acetylcholine-induced endothelium-derived contracting factor in hypoxic pulmonary hypertensive rats. J Appl Physiol. 1999;86:1687-1695.
-
(1999)
J Appl Physiol
, vol.86
, pp. 1687-1695
-
-
Maruyama, J.1
Yokochi, A.2
Maruyama, K.3
Nosaka, S.4
-
22
-
-
0033835030
-
Thrombin stimulates the expression of PDGF in lung epithelial cells
-
Shimizu S, Gabazza EC, Hayashi T, Ido M, Adachi Y, Suzuki K. Thrombin stimulates the expression of PDGF in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2000;279:L503-510.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Shimizu, S.1
Gabazza, E.C.2
Hayashi, T.3
Ido, M.4
Adachi, Y.5
Suzuki, K.6
-
23
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 1983;11:1475-1489.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
24
-
-
0032522489
-
Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production
-
Bonder CS, Dickensheets HL, Finlay-Jones JJ, Donnelly RP, Hart PH. Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production. J Immunol. 1998;160:4048-4056.
-
(1998)
J Immunol
, vol.160
, pp. 4048-4056
-
-
Bonder, C.S.1
Dickensheets, H.L.2
Finlay-Jones, J.J.3
Donnelly, R.P.4
Hart, P.H.5
-
25
-
-
0001606677
-
Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules
-
Chen XH, Patel BK, Wang LM, et al. Jak1 expression is required for mediating interleukin-4-induced tyrosine phosphorylation of insulin receptor substrate and Stat6 signaling molecules. J Biol Chem. 1997;272:6556-6560.
-
(1997)
J Biol Chem
, vol.272
, pp. 6556-6560
-
-
Chen, X.H.1
Patel, B.K.2
Wang, L.M.3
-
26
-
-
0032813814
-
Thrombin in the airways of asthmatic patients
-
Gabazza EC, Taguchi O, Tamaki S, et al. Thrombin in the airways of asthmatic patients. Lung. 1999;177:253-262.
-
(1999)
Lung
, vol.177
, pp. 253-262
-
-
Gabazza, E.C.1
Taguchi, O.2
Tamaki, S.3
-
27
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
Coughlin SR. Thrombin signalling and protease-activated receptors. Nature. 2000;407:258-264.
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
28
-
-
0032793201
-
Alpha-Thrombin stimulates contraction of human bronchial rings by activation of protease-activated receptors
-
Hauck RW, Schulz C, Schomig A, Hoffman RK, Panettieri RA Jr. Alpha-Thrombin stimulates contraction of human bronchial rings by activation of protease-activated receptors. Am J Physiol. 1999;1277:L22-L29.
-
(1999)
Am J Physiol
, vol.1277
-
-
Hauck, R.W.1
Schulz, C.2
Schomig, A.3
Hoffman, R.K.4
Panettieri Jr., R.A.5
-
29
-
-
10544228517
-
Protein C activation in NIDDM patients
-
Gabazza EC, Takeya H, Deguchi H, et al. Protein C activation in NIDDM patients. Diabetologia. 1996;39:1455-1461.
-
(1996)
Diabetologia
, vol.39
, pp. 1455-1461
-
-
Gabazza, E.C.1
Takeya, H.2
Deguchi, H.3
-
30
-
-
0027175429
-
Eosinophil cationic granule proteins impair thrombomodulin function. A potential mechanism for thromboembolism in hypereosinophilic heart disease
-
Slungaard A, Vercellotti GM, Tran T, Gleich GJ, Key NS. Eosinophil cationic granule proteins impair thrombomodulin function. A potential mechanism for thromboembolism in hypereosinophilic heart disease. J Clin Invest. 1993;91:1721-1730.
-
(1993)
J Clin Invest
, vol.91
, pp. 1721-1730
-
-
Slungaard, A.1
Vercellotti, G.M.2
Tran, T.3
Gleich, G.J.4
Key, N.S.5
-
31
-
-
0037036069
-
Activation of endothelial cell protease activated receptor 1 by the protein C pathway
-
Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W. Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science. 2002;296:1880-1882.
-
(2002)
Science
, vol.296
, pp. 1880-1882
-
-
Riewald, M.1
Petrovan, R.J.2
Donner, A.3
Mueller, B.M.4
Ruf, W.5
-
32
-
-
0032750835
-
Th2 cytokines and GATA-3 in asthma: New insights into the regulation of airway inflammation
-
Ray A, Cohn L. Th2 cytokines and GATA-3 in asthma: new insights into the regulation of airway inflammation. J Clin Invest. 1999;104:985-993.
-
(1999)
J Clin Invest
, vol.104
, pp. 985-993
-
-
Ray, A.1
Cohn, L.2
-
33
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K, van Deursen J, Sangster MY, et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature. 1996;380:630-633.
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
Van Deursen, J.2
Sangster, M.Y.3
-
35
-
-
0032476742
-
Essential role of nuclear kappaB in the induction of eosinophilia in allergic airway inflammation
-
Yang L, Cohn L, Zhang DH, Homer R, Ray A, Ray P. Essential role of nuclear kappaB in the induction of eosinophilia in allergic airway inflammation. J Exp Med. 1998;188:1739-1750.
-
(1998)
J Exp Med
, vol.188
, pp. 1739-1750
-
-
Yang, L.1
Cohn, L.2
Zhang, D.H.3
Homer, R.4
Ray, A.5
Ray, P.6
-
36
-
-
0028804551
-
Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
-
Sha WC, Liou HC, Tuomanen EI, Baltimore D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell. 1995;80:321-330.
-
(1995)
Cell
, vol.80
, pp. 321-330
-
-
Sha, W.C.1
Liou, H.C.2
Tuomanen, E.I.3
Baltimore, D.4
-
37
-
-
0035222187
-
A critical role for NF-kappa B in GATA-3 expression and Th2 differentiation in allergic airway inflammation
-
Das J, Chen CH, Yang L, Cohn L, Ray P, Ray A. A critical role for NF-kappa B in GATA-3 expression and Th2 differentiation in allergic airway inflammation. Nat Immunol. 2001;1:45-50.
-
(2001)
Nat Immunol
, vol.1
, pp. 45-50
-
-
Das, J.1
Chen, C.H.2
Yang, L.3
Cohn, L.4
Ray, P.5
Ray, A.6
-
38
-
-
0031842614
-
Interaction of STAT6 and NF-κB: Direct association and synergistic activation of interleukin-4 induced transcription
-
Shen CH, Stavenezer J. Interaction of STAT6 and NF-κB: direct association and synergistic activation of interleukin-4 induced transcription. Mol Cell Biol. 1998;18:3395-3404.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3395-3404
-
-
Shen, C.H.1
Stavenezer, J.2
-
39
-
-
0345062267
-
Functional synergism of STA6 with either NF-κB or PU.1 to mediate IL-4-induced activation of IgE germline gene transcription
-
Stutz AM, Woisetschlager M. Functional synergism of STA6 with either NF-κB or PU.1 to mediate IL-4-induced activation of IgE germline gene transcription. J Immunol. 1999;163:4383-4391.
-
(1999)
J Immunol
, vol.163
, pp. 4383-4391
-
-
Stutz, A.M.1
Woisetschlager, M.2
-
40
-
-
0030445634
-
Involvement of nuclear factor-kappa B activation in IgE synthesis in human B cells
-
Yanagihara Y, Basaki Y, Ikizawa K, Kajiwara K, Koshio T, Akiyama K. Involvement of nuclear factor-kappa B activation in IgE synthesis in human B cells. J Allergy Clin Immunol. 1996;98:S224-229.
-
(1996)
J Allergy Clin Immunol
, vol.98
-
-
Yanagihara, Y.1
Basaki, Y.2
Ikizawa, K.3
Kajiwara, K.4
Koshio, T.5
Akiyama, K.6
-
41
-
-
0036344597
-
Direct effect of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman DA, Huang X, Koth LL, et al. Direct effect of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med. 2002;8:885-889.
-
(2002)
Nat Med
, vol.8
, pp. 885-889
-
-
Kuperman, D.A.1
Huang, X.2
Koth, L.L.3
|