-
1
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell LH, Weinert TA 1989 Checkpoints: controls that ensure the order of cell cycle events. Science 246:629-634
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
2
-
-
0027090115
-
Mammalian genes induced by radiation; activation of genes associated with growth control
-
Fornace Jr AJ 1992 Mammalian genes induced by radiation; activation of genes associated with growth control. Annu Rev Genet 26:507-526
-
(1992)
Annu Rev Genet
, vol.26
, pp. 507-526
-
-
Fornace Jr., A.J.1
-
3
-
-
0033615657
-
Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line
-
Hayakawa J, Ohmichi M, Kurachi H, Ikegami H, Kimura A, Matsuoka T, Jikihara H, Mercola D, Murata Y 1999 Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line. J Biol Chem 274:31648-31654
-
(1999)
J Biol Chem
, vol.274
, pp. 31648-31654
-
-
Hayakawa, J.1
Ohmichi, M.2
Kurachi, H.3
Ikegami, H.4
Kimura, A.5
Matsuoka, T.6
Jikihara, H.7
Mercola, D.8
Murata, Y.9
-
4
-
-
0034326803
-
Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin
-
HayakawaJ, Ohmichi M, Kurachi H, Kanda Y, Hisamoto K, Nishio Y, Adachi K, Tasaka K, Kanzaki T, Murata Y 2000 Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin. Cancer Res 60:5988-5994
-
(2000)
Cancer Res
, vol.60
, pp. 5988-5994
-
-
Hayakawa, J.1
Ohmichi, M.2
Kurachi, H.3
Kanda, Y.4
Hisamoto, K.5
Nishio, Y.6
Adachi, K.7
Tasaka, K.8
Kanzaki, T.9
Murata, Y.10
-
5
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME 1999 Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96:857-868
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
6
-
-
0027521658
-
Fusion of a fork head domain geneto PAX3 in the solid tumour alveolar rhabdomyosarcoma
-
Galili N, Davis RJ, Fredericks WJ, Mukhopadhyay S, Rauscher 3rd FJ, Emanuel BS, Rovera G, Barr FG 1993 Fusion of a fork head domain geneto PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet 5:230-235
-
(1993)
Nat Genet
, vol.5
, pp. 230-235
-
-
Galili, N.1
Davis, R.J.2
Fredericks, W.J.3
Mukhopadhyay, S.4
Rauscher III, F.J.5
Emanuel, B.S.6
Rovera, G.7
Barr, F.G.8
-
7
-
-
0030869789
-
AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a Forkhead transcriptional factor subfamily
-
Hillion J, Le Coniat M, Jonveaux P, Berger R, Bernard OA 1997 AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a Forkhead transcriptional factor subfamily. Blood 90:3714-3719
-
(1997)
Blood
, vol.90
, pp. 3714-3719
-
-
Hillion, J.1
Le Coniat, M.2
Jonveaux, P.3
Berger, R.4
Bernard, O.A.5
-
8
-
-
0032518255
-
Cloning and characterization of three human Forkhead genes that comprise an FKHR-like gene subfamily
-
Anderson MJ, Viars CS, Czekay S, Cavenee WK, Arden KC 1998 Cloning and characterization of three human Forkhead genes that comprise an FKHR-like gene subfamily. Genomics 47:187-199
-
(1998)
Genomics
, vol.47
, pp. 187-199
-
-
Anderson, M.J.1
Viars, C.S.2
Czekay, S.3
Cavenee, W.K.4
Arden, K.C.5
-
9
-
-
0031031378
-
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
-
Borkhardt A, Repp R, Haas OA, Leis T, Harbott J, Kreuder J, Hammermann J, Henn T, Lampert F 1997 Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23). Oncogene 14:195-202
-
(1997)
Oncogene
, vol.14
, pp. 195-202
-
-
Borkhardt, A.1
Repp, R.2
Haas, O.A.3
Leis, T.4
Harbott, J.5
Kreuder, J.6
Hammermann, J.7
Henn, T.8
Lampert, F.9
-
10
-
-
0030659557
-
The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G 1997 The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389:994-999
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
11
-
-
0030744833
-
Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells
-
Villunger A, Egle A, Kos M, Hartmann BL, Geley S, Kofler R, Greil R 1997 Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells. Cancer Res 57:3331-3334
-
(1997)
Cancer Res
, vol.57
, pp. 3331-3334
-
-
Villunger, A.1
Egle, A.2
Kos, M.3
Hartmann, B.L.4
Geley, S.5
Kofler, R.6
Greil, R.7
-
12
-
-
0036892132
-
Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis
-
Rokudai S, Fujita N, Kitahara O, Nakamura Y, Tsuruo T 2002 Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis. Mol Cell Biol 22:8695-8708
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8695-8708
-
-
Rokudai, S.1
Fujita, N.2
Kitahara, O.3
Nakamura, Y.4
Tsuruo, T.5
-
13
-
-
0037134040
-
DNA repair pathway stimulated by the Forkhead transcription factor FOXO3a through the Gadd45 protein
-
Tran H, Brunet A, Grenier JM, Datta SR, Fornace Jr AJ, DiStefano PS, Chiang LW, Greenberg ME 2002 DNA repair pathway stimulated by the Forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296:530-534
-
(2002)
Science
, vol.296
, pp. 530-534
-
-
Tran, H.1
Brunet, A.2
Grenier, J.M.3
Datta, S.R.4
Fornace Jr., A.J.5
DiStefano, P.S.6
Chiang, L.W.7
Greenberg, M.E.8
-
14
-
-
0021878218
-
Augmentation of Adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion
-
Hamilton TC, Winker MA, Louie KG, Batist G, Behrens BC, Tsuruo T, Grotzinger KR, McKoy WM, Young RC, Ozols RF 1985 Augmentation of Adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion. Biochem Pharmacol 34:2583-2586
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 2583-2586
-
-
Hamilton, T.C.1
Winker, M.A.2
Louie, K.G.3
Batist, G.4
Behrens, B.C.5
Tsuruo, T.6
Grotzinger, K.R.7
McKoy, W.M.8
Young, R.C.9
Ozols, R.F.10
-
15
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME 1997 Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231-241
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
16
-
-
0034212582
-
Involvement of 14-3-3 proteins in nuclear localization of telomerase
-
Seimiyam H, Sawada H, Muramatsu Y, Shimizu M, Ohko K, Yamane K, Tsuruo T 2000 Involvement of 14-3-3 proteins in nuclear localization of telomerase. EMBO J 19:2652-2661
-
(2000)
EMBO J
, vol.19
, pp. 2652-2661
-
-
Seimiyam, H.1
Sawada, H.2
Muramatsu, Y.3
Shimizu, M.4
Ohko, K.5
Yamane, K.6
Tsuruo, T.7
-
17
-
-
18544367200
-
Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel
-
Mabuchi S, Ohmichi M, Kimura A, Hisamoto K, Hayakawa J, Nishio Y, Adachi K, Takahashi K, Arimoto-Ishida E, Nakatsuji Y, Tasaka K, Murata Y 2002 Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel. J Biol Chem 277:33490-33500
-
(2002)
J Biol Chem
, vol.277
, pp. 33490-33500
-
-
Mabuchi, S.1
Ohmichi, M.2
Kimura, A.3
Hisamoto, K.4
Hayakawa, J.5
Nishio, Y.6
Adachi, K.7
Takahashi, K.8
Arimoto-Ishida, E.9
Nakatsuji, Y.10
Tasaka, K.11
Murata, Y.12
-
18
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
19
-
-
0032723879
-
Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human ovarian cancer cell line
-
Kimura A, Ohmichi M, Kurachi H, Ikegami H, Hayakawa J, Tasaka K, Kanada Y, Jikihara H, Matsuura N, Murata Y 1999 Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human ovarian cancer cell line. Cancer Res 59:5133-5142
-
(1999)
Cancer Res
, vol.59
, pp. 5133-5142
-
-
Kimura, A.1
Ohmichi, M.2
Kurachi, H.3
Ikegami, H.4
Hayakawa, J.5
Tasaka, K.6
Kanada, Y.7
Jikihara, H.8
Matsuura, N.9
Murata, Y.10
-
20
-
-
0034647542
-
Activation of the luteinizing hormone beta promoter by gonadotropin-releasing hormone requires c-Jun NH2-terminal protein kinase
-
Yokoi T, Ohmichi M, Tasaka K, Kimura A, Kanda Y, Hayakawa J, Tahara M, Hisamoto K, Kurachi H, Murata Y 2000 Activation of the luteinizing hormone beta promoter by gonadotropin-releasing hormone requires c-Jun NH2-terminal protein kinase. J Biol Chem 275:21639-21647
-
(2000)
J Biol Chem
, vol.275
, pp. 21639-21647
-
-
Yokoi, T.1
Ohmichi, M.2
Tasaka, K.3
Kimura, A.4
Kanda, Y.5
Hayakawa, J.6
Tahara, M.7
Hisamoto, K.8
Kurachi, H.9
Murata, Y.10
-
21
-
-
0034603087
-
Prolactin-releasing peptide activation of the prolactin promoter is differentially mediated by extracellular signal-regulated protein kinase and c-Jun N-terminal protein kinase
-
Kimura A, Ohmichi M, Tasaka K, Kanda Y, Ikegami H, Hayakawa J, Hisamoto K, Morishige K, Hinuma S, Kurachi H, Murata Y 2000 Prolactin-releasing peptide activation of the prolactin promoter is differentially mediated by extracellular signal-regulated protein kinase and c-Jun N-terminal protein kinase. J Biol Chem 275:3667-3674
-
(2000)
J Biol Chem
, vol.275
, pp. 3667-3674
-
-
Kimura, A.1
Ohmichi, M.2
Tasaka, K.3
Kanda, Y.4
Ikegami, H.5
Hayakawa, J.6
Hisamoto, K.7
Morishige, K.8
Hinuma, S.9
Kurachi, H.10
Murata, Y.11
-
22
-
-
0022345333
-
X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2[d(pGpG)]]
-
Sherman SE, Gibson D, Wang AH, Lippard SJ 1985 X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2[d(pGpG)]]. Science 230:412-417
-
(1985)
Science
, vol.230
, pp. 412-417
-
-
Sherman, S.E.1
Gibson, D.2
Wang, A.H.3
Lippard, S.J.4
-
23
-
-
0023750017
-
Increased DNA repair as a mechanism of acquired resistance to cis-diaminedichloroplatinum (II) in human ovarian cancer cell linens
-
Masuda H, Ozols RF, Lai G-M, Fojo A, Rothenberg M, Hamilton TC 1988 Increased DNA repair as a mechanism of acquired resistance to cis-diaminedichloroplatinum (II) in human ovarian cancer cell linens. Cancer Res 48:5713-5716
-
(1988)
Cancer Res
, vol.48
, pp. 5713-5716
-
-
Masuda, H.1
Ozols, R.F.2
Lai, G.-M.3
Fojo, A.4
Rothenberg, M.5
Hamilton, T.C.6
-
24
-
-
0027472165
-
Mechanisms of drug resistance in ovarian cancer
-
Johnson SW, Ozols RF, Hamilton TC 1993 Mechanisms of drug resistance in ovarian cancer. Cancer 71:644-649
-
(1993)
Cancer
, vol.71
, pp. 644-649
-
-
Johnson, S.W.1
Ozols, R.F.2
Hamilton, T.C.3
-
25
-
-
0027511187
-
Mechanisms and modulation of resistance to chemotherapy in ovarian cancer
-
Perez RP, Hamilton TC, Ozols RF, Young RC 1993 Mechanisms and modulation of resistance to chemotherapy in ovarian cancer. Cancer 71:1571-1580
-
(1993)
Cancer
, vol.71
, pp. 1571-1580
-
-
Perez, R.P.1
Hamilton, T.C.2
Ozols, R.F.3
Young, R.C.4
-
26
-
-
0031020450
-
Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in untreated human ovarian cancer cell lines
-
Johnson SW, Laub PB, Beesley JS, Ozols RF, Hamilton TC 1997 Increased platinum-DNA damage tolerance is associated with cisplatin resistance and cross-resistance to various chemotherapeutic agents in untreated human ovarian cancer cell lines. Cancer Res 57:850-856
-
(1997)
Cancer Res
, vol.57
, pp. 850-856
-
-
Johnson, S.W.1
Laub, P.B.2
Beesley, J.S.3
Ozols, R.F.4
Hamilton, T.C.5
-
27
-
-
0029808528
-
Preclinical combination therapy with gemcitabine and mechanisms of resistance
-
Peters GJ, Ruiz van Haperen VW, Bergman AM, Veerman G, Smitskamp-Wilms E, van Moorsel CJ, Kuiper CM, Braakhuis BJ 1996 Preclinical combination therapy with gemcitabine and mechanisms of resistance. Semin Oncol 23:16-24
-
(1996)
Semin Oncol
, vol.23
, pp. 16-24
-
-
Peters, G.J.1
Ruiz Van Haperen, V.W.2
Bergman, A.M.3
Veerman, G.4
Smitskamp-Wilms, E.5
Van Moorsel, C.J.6
Kuiper, C.M.7
Braakhuis, B.J.8
-
28
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S, Moelling K 1999 Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 286:1741-1744
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
-
29
-
-
0034699325
-
Phosphorylation and nuclear exclusion of the Forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells
-
Jackson JG, Kreisberg JI, Koterba AP, Yee D, Brattain MG 2000 Phosphorylation and nuclear exclusion of the Forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells. Oncogene 19:4574-4581
-
(2000)
Oncogene
, vol.19
, pp. 4574-4581
-
-
Jackson, J.G.1
Kreisberg, J.I.2
Koterba, A.P.3
Yee, D.4
Brattain, M.G.5
-
30
-
-
0037472647
-
Estrogen regulation of Pak1 and FKHR Pathways in breast cancer cells
-
Mazumdar A, Kumar R 2003 Estrogen regulation of Pak1 and FKHR Pathways in breast cancer cells. FEBS Lett 535:6-10
-
(2003)
FEBS Lett
, vol.535
, pp. 6-10
-
-
Mazumdar, A.1
Kumar, R.2
-
31
-
-
0035992286
-
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of Taxol and mitogen-activated protein kinase kinase inhibition
-
MacKeigan JP, Taxman DJ, Hunter D, Earp 3rd HS, Graves LM, Ting JP 2002 Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of Taxol and mitogen-activated protein kinase kinase inhibition. Clin Cancer Res 8:7091-2099
-
(2002)
Clin Cancer Res
, vol.8
, pp. 7091-12099
-
-
MacKeigan, J.P.1
Taxman, D.J.2
Hunter, D.3
Earp III, H.S.4
Graves, L.M.5
Ting, J.P.6
-
32
-
-
0037229714
-
Overexpression of AKT2/protein kinase Bβ leads to up-regulation of β1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells
-
Arboleda MJ, Lyons JF, Kabbinavar FF, Bray MR, Snow BE, Ayala R, Danino M, Karlan BY, Slamon DJ 2003 Overexpression of AKT2/protein kinase Bβ leads to up-regulation of β1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells. Cancer Res 63:196-206
-
(2003)
Cancer Res
, vol.63
, pp. 196-206
-
-
Arboleda, M.J.1
Lyons, J.F.2
Kabbinavar, F.F.3
Bray, M.R.4
Snow, B.E.5
Ayala, R.6
Danino, M.7
Karlan, B.Y.8
Slamon, D.J.9
-
33
-
-
0037424469
-
A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-β 1 signaling cascade
-
Kobayashi H, Suzuki M, Tanaka Y, Kanayama N, Terao T 2003 A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-β 1 signaling cascade. J Biol Chem 278:7790-7799
-
(2003)
J Biol Chem
, vol.278
, pp. 7790-7799
-
-
Kobayashi, H.1
Suzuki, M.2
Tanaka, Y.3
Kanayama, N.4
Terao, T.5
|