Manipulation of innate immunity by bacterial pathogens

Current Opinion in Immunology

Volumn 17, Issue 1, 2005, Pages 25-28

  Portnoy, Daniel A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; INTERFERON; TOLL LIKE RECEPTOR 4;

BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; HOST; IMMUNOPATHOGENESIS; INFLAMMATION; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; MYCOBACTERIOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN INDUCTION; PROTEIN MODIFICATION; REVIEW; YERSINIA;

EID: 11844288885     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2004.11.002     Document Type: Article

References (38)

1. K. Takeda, T. Kaisho, and S. Akira Toll-like receptors Annu Rev Immunol 21 2003 335 376
2. B. Beutler Inferences, questions and possibilities in Toll-like receptor signalling Nature 430 2004 257 263
3. A. Ozinsky, D.M. Underhill, J.D. Fontenot, A.M. Hajjar, K.D. Smith, C.B. Wilson, L. Schroeder, and A. Aderem The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors Proc Natl Acad Sci USA 97 2000 13766 13771
4. A. Aderem Phagocytosis and the inflammatory response J Infect Dis 187(Suppl 2) 2003 S340 S345
5. T.R. Hawn, A. Verbon, K.D. Lettinga, L.P. Zhao, S.S. Li, R.J. Laws, S.J. Skerrett, B. Beutler, L. Schroeder, and A. Nachman A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease J Exp Med 198 2003 1563 1572
6. A. Vazquez-Torres, B.A. Vallance, M.A. Bergman, B.B. Finlay, B.T. Cookson, J. Jones-Carson, and F.C. Fang Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network J Immunol 172 2004 6202 6208
7. A. Sing, D. Rost, N. Tvardovskaia, A. Roggenkamp, A. Wiedemann, C.J. Kirschning, M. Aepfelbacher, and J. Heesemann Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression J Exp Med 196 2002 1017 1024
8. J. Mecsas Use of signature-tagged mutagenesis in pathogenesis studies Curr Opin Microbiol 5 2002 33 37
9. C.M. Sassetti, and E.J. Rubin Genetic requirements for mycobacterial survival during infection Proc Natl Acad Sci USA 100 2003 12989 12994 This reference describes an elegant use of microbial genomics and microarray analysis to identify bacterial genes that are required for growth in animals.
10. P. Cossart, and P.J. Sansonetti Bacterial invasion: the paradigms of enteroinvasive pathogens Science 304 2004 242 248
11. J.E. Galan The cell biology of microbial infections: coming of age J Cell Biol 158 2002 387 388
12. M.W. Hornef, M.J. Wick, M. Rhen, and S. Normark Bacterial strategies for overcoming host innate and adaptive immune responses Nat Immunol 3 2002 1033 1040
13. R.P. Darveau, T.T. Pham, K. Lemley, R.A. Reife, B.W. Bainbridge, S.R. Coats, W.N. Howald, S.S. Way, and A.M. Hajjar Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both Toll-like receptors 2 and 4 Infect Immun 72 2004 5041 5051 In this manuscript a previously unrecognized heterogeneity of lipid A is observed for a dental pathogen. These different lipid A molecules have distinct biological activities.
14. H. D'Hauteville, S. Khan, D.J. Maskell, A. Kussak, A. Weintraub, J. Mathison, R.J. Ulevitch, N. Wuscher, C. Parsot, and P.J. Sansonetti Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium J Immunol 168 2002 5240 5251
15. K. Kawasaki, R.K. Ernst, and S.I. Miller 3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through Toll-like receptor 4 J Biol Chem 279 2004 20044 20048
16. R. Rebeil, R.K. Ernst, B.B. Gowen, S.I. Miller, and B.J. Hinnebusch Variation in lipid A structure in the pathogenic yersiniae Mol Microbiol 52 2004 1363 1373
17. R.R. Brubaker Interleukin-10 and inhibition of innate immunity to Yersiniae: roles of Yops and LcrV (V antigen) Infect Immun 71 2003 3673 3681
18. E.J. Kerschen, D.A. Cohen, A.M. Kaplan, and S.C. Straley The plague virulence protein YopM targets the innate immune response by causing a global depletion of NK cells Infect Immun 72 2004 4589 4602 In this paper, one of the Yersinia effector molecules that traffics to the cell nucleus modifies innate immune responses that cause a depletion of NK cells.
19. M. Mackaness Cellular resistance to infection J Exp Med 116 1962 381
20. E.R. Unanue Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response Immunol Rev 158 1997 11 25
21. D.A. Portnoy, V. Auerbuch, and I.J. Glomski The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity J Cell Biol 158 2002 409 414
22. R.L. McCaffrey, P. Fawcett, M. O'Riordan, K.D. Lee, E.A. Havell, P.O. Brown, and D.A. Portnoy A specific gene expression program triggered by Gram-positive bacteria in the cytosol Proc Natl Acad Sci USA 101 2004 11386 11391
23. M. O'Riordan, C.H. Yi, R. Gonzales, K.D. Lee, and D.A. Portnoy Innate recognition of bacteria by a macrophage cytosolic surveillance pathway Proc Natl Acad Sci USA 99 2002 13861 13866
24. •].
25. •].
26. + macrophages.
27. N. Inohara, and G. Nunez NODs: intracellular proteins involved in inflammation and apoptosis Nat Rev Immunol 3 2003 371 382
28. L.L. Lenz, S. Mohammadi, A. Geissler, and D.A. Portnoy SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis Proc Natl Acad Sci USA 100 2003 12432 12437
29. T. Watanabe, A. Kitani, P.J. Murray, and W. Strober NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses Nat Immunol 5 2004 800 808
30. T.R. Frieden, T.R. Sterling, S.S. Munsiff, C.J. Watt, and C. Dye Tuberculosis Lancet 362 2003 887 899
31. G.J. Nau, J.F. Richmond, A. Schlesinger, E.G. Jennings, E.S. Lander, and R.A. Young Human macrophage activation programs induced by bacterial pathogens Proc Natl Acad Sci USA 99 2002 1503 1508
32. S.A. Stanley, S. Raghavan, W.W. Hwang, and J.S. Cox Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system Proc Natl Acad Sci USA 100 2003 13001 13006
33. S.M. Fortune, A. Solache, A. Jaeger, P.J. Hill, J.T. Belisle, B.R. Bloom, E.J. Rubin, and J.D. Ernst Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms J Immunol 172 2004 6272 6280 This manuscript shows that M. tuberculosis has two molecules that suppress macrophage responses to IFN-γ, a lipoprotein and a peptidoglycan fragment.
34. R.K. Pai, M. Convery, T.A. Hamilton, W.H. Boom, and C.V. Harding Inhibition of IFN-gamma-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: a potential mechanism for immune evasion J Immunol 171 2003 175 184
35. •].
36. •].
37. •], it was discovered that a specific mutation in M. tuberculosis causes the bacteria to be hypervirulent in mice.
38. S.E. Girardin, J.P. Hugot, and P.J. Sansonetti Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing Trends Immunol 24 2003 652 658