Directed evolution of protein inhibitors of DNA-nucleases by in vitro compartmentalization (IVC) and nano-droplet delivery

Journal of Molecular Biology

Volumn 345, Issue 5, 2005, Pages 1015-1026

  Bernath, Kalia ^a,b   Magdassi, Shlomo ^b   Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

colicin; directed evolution; emulsion; immunity protein; nano droplets

Indexed keywords

COBALT; COLICIN; COLICIN E9; DEOXYRIBONUCLEASE; ENZYME INHIBITOR; NICKEL; NUCLEASE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL COMPARTMENTALIZATION; DIRECTED MOLECULAR EVOLUTION; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE LIBRARY; GENE MUTATION; GENE TECHNOLOGY; GENETIC ENGINEERING; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NANOTECHNOLOGY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RNA TRANSLATION; TRANSPORT KINETICS;

EID: 11844273937     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.11.017     Document Type: Article

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