The metabotropic P2Y 4 receptor participates in the commitment to differentiation and cell death of human neuroblastoma SH-SY5Y cells

Neurobiology of Disease

Volumn 18, Issue 1, 2005, Pages 100-109

  Cavaliere, Fabio ^a   Nestola, Valeria ^a   Amadio, Susanna ^a,b   D'Ambrosi, Nadia ^a,b   Angelini, Daniela F ^a   Sancesario, Giuseppe ^a,b   Bernardi, Giorgio ^a,b   Volonté, Cinzia ^a,c  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c CNR   (Italy)

Author keywords

Dibutiryl cAMP; Extracellular nucleotides; Immediate early genes; Neurofilament proteins; UTP

Indexed keywords

BUCLADESINE; METABOTROPIC RECEPTOR; NEUROFILAMENT PROTEIN; PROTEIN C FOS; PURINE P2X1 RECEPTOR; PURINE P2X2 RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X4 RECEPTOR; PURINE P2X5 RECEPTOR; PURINE P2X6 RECEPTOR; PURINE P2X7 RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y12 RECEPTOR; PURINE P2Y2 RECEPTOR; PURINE P2Y4 RECEPTOR; PURINE P2Y6 RECEPTOR; TRANSCRIPTION FACTOR FOSB; URIDINE TRIPHOSPHATE; NEUROFILAMENT PROTEIN L; PURINE P2 RECEPTOR; TRANSCRIPTION FACTOR;

ARTICLE; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; CYTOFLUOROMETRY; DNA DAMAGE; GENETIC LINKAGE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; BRAIN TUMOR; CELL DIFFERENTIATION; CELL TRANSFORMATION; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; IMMEDIATE EARLY GENE; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

BRAIN NEOPLASMS; BUCLADESINE; CELL DEATH; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, IMMEDIATE-EARLY; HUMANS; NEUROBLASTOMA; NEUROFILAMENT PROTEINS; RECEPTORS, PURINERGIC P2; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION; URIDINE TRIPHOSPHATE;

EID: 11844266620     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.09.001     Document Type: Article

References (66)

1. M.S. Airaksinen, and M. Saarma The GDNF family: signalling, biological functions and therapeutic value Nat. Rev., Neurosci. 5 2002 383 394
2. S. Amadio, N. D'Ambrosi, F. Cavaliere, B. Murra, G. Sancesario, G. Bernardi, G. Burnstock, and C. Volonté P2 receptor modulation and cytotoxic function in cultured CNS neurons Neuropharmacology 42 2002 489 501
3. J.C. Baskey, B.E. Kalisch, W.L. Davis, S.O. Meakin, and R.J. Rylett PC12nnr5 cells expressing TrkA receptors undergo morphological but not cholinergic phenotypic differentiation in response to nerve growth factor J. Neurochem. 80 2002 501 511
4. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 252
5. V. Bronte, B. Macino, A. Zambon, A. Rosato, S. Mandruzzato, P. Zanovello, and D. Collavo Protein tyrosine kinases and phosphatases control apoptosis induced by extracellular adenosine 5′ triphosphate Biochem. Biophys. Res. Commun. 218 1996 344 351
6. F. Cavaliere, G. Sancesario, G. Bernardi, and C. Volonté Extracellular ATP and nerve growth factor intensify hypoglycemia-induced cell death in primary neurons: role of P2 and NGFRp75 receptors J. Neurochem. 83 2002 1129 1138
7. F. Cavaliere, F. Florenzano, S. Amadio, F.R. Fusco, M.T. Viscomi, N. D'Ambrosi, F. Vacca, G. Sancesario, G. Bernardi, M. Molinari, and C. Volonté Up-regulation of P2X2, P2X4 receptor and ischemic cell death: prevention by P2 antagonists Neuroscience 120 2003 85 98
8. F. Cavaliere, S. Amadio, G. Sancesario, G. Bernardi, C. Volonté, and Synaptic P2X7 and oxygen/glucose deprivation in organotypic hippocampal cultures J. Cereb. Blood Flow Metab. 24 2004 392 398
9. F. Cavaliere, S. Amadio, D.F. Angelini, G. Sancesario, G. Bernardi, and C. Volonte Role of the metabotropic P2Y4 receptor during hypoglycemia: cross talk with the ionotropic NMDAR1 receptor Exp. Cell Res. 300 2004 149 158
10. J.H. Cho, I.S. Kwon, S. Kim, S.H. Ghil, M.J. Tsai, Y.S. Kim, Y.D. Lee, and H. Suh-Kim Overexpression of BETA2/NeuroD induces neurite outgrowth in F11 neuroblastoma cells J. Neurochem. 77 2001 103 109
11. P. Correale, P. Tagliaferri, R. Guarrasi, M. Caraglia, M. Giuliano, M.R. Marinetti, A.R. Bianco, and A. Procopio Extracellular adenosine 5′ triphosphate involvement in the death of LAK-engaged human tumor cells via P2X-receptor activation Immunol. Lett. 55 1997 69 78
12. N. D'Ambrosi, F. Cavaliere, D. Merlo, L. Milazzo, D. Mercanti, and C. Volonté Antagonists of P2 receptor prevent NGF-dependent neuritogenesis in PC12 cells Neuropharmacology 39 2000 1083 1094
13. N. D'Ambrosi, B. Murra, F. Cavaliere, S. Amadio, G. Bernardi, G. Burnstock, and C. Volonté Interaction between ATP and nerve growth factor signalling in the survival and neuritic outgrowth from PC12 cells Neuroscience 108 2001 527 534
14. Z. Darzynkiewicz, G. Juan, X. Li, W. Gorczyca, T. Murakami, and F. Traganos Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis) Cytometry 27 1997 1 20
15. R. Dhavan, and L.H. Tsai A decade of CDK5 Nat. Rev., Mol. Cell Biol. 2 2001 749 759
16. F. Di Virgilio, P. Chiozzi, D. Ferrari, S. Falzoni, J.M. Sanz, A. Morelli, M. Torboli, G. Bolognesi, and O.R. Baricordi Nucleotide receptors: an emerging family of regulatory molecules in blood cells Blood 97 2001 587 600
17. G. Duncan, R.A. Riach, M.R. Williams, S.F. Webb, A.P. Dawson, and J.R. Reddan Calcium mobilisation modulates growth of lens cells Cell Calcium 19 1996 83 89
18. M. Encinas, M. Iglesias, N. Llecha, and J.X. Comella Extracellular- regulated kinases and phosphatidylinositol 3-kinase are involved in brain-derived neurotrophic factor-mediated survival and neuritogenesis of the neuroblastoma cell line SH-SY5Y J. Neurochem. 73 1999 1409 1421
19. J.M. Estrela, E. Obrador, J. Navarro, M.C. Lasso de la Vega, and J.A. Pellicer Elimination of Ehrlich tumours by ATP-induced growth inhibition, glutathione depletion and X-rays Nat. Med. 1 1995 84 88
20. W.G. Fang, F. Pirnia, Y.J. Bang, C.E. Myers, and J.B. Trepel P2-purinergic receptor agonists inhibit the growth of androgen-independent prostate carcinoma cells J. Clin. Invest. 89 1992 191 196
21. N.J. Francis, and S.C. Landis Cellular and molecular determinants of sympathetic neuron development Annu. Rev. Neurosci. 22 1999 541 566
22. D.A. Frank, and M.E. Greenberg CREB: a mediator of long-term memory from mollusks to mammals Cell 79 1994 5 8
23. B.B. Fredholm, M.P. Abbracchio, G. Burnstock, J.W. Daly, T.K. Harden, K.A. Jacobson, P. Leff, and M. Williams Nomenclature and classification of purino-ceptors Pharmacol. Rev. 46 1994 143 156
24. A.V. Greig, C. Linge, G. Terenghi, D.A. McGrouther, and G. Burnstock Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes J. Invest. Dermatol. 120 2003 1007 1015
25. T. Hishiki, Y. Nimura, E. Isogai, K. Kondo, S. Ichimiya, Y. Nakamura, T. Ozaki, S. Sakiyama, M. Hirose, N. Seki, H. Takahashi, N. Ohnuma, M. Tanabe, and A. Nakagawara Glial cell line-derived neurotrophic factor/neurturin-induced differentiation and its enhancement by retinoic acid in primary human neuroblastomas expressing c-Ret, GFR alpha-1, and GFR alpha-2 Cancer Res. 58 1998 2158 2165
26. M. Höpfner, K. Lemmer, A. Jansen, C. Hanski, E.O. Riecken, M. Gavish, B. Mann, H. Buhr, G. Glassmeier, and H. Scherubl Expression of functional P2-purinergic receptors in primary cultures of human colorectal carcinoma cells Biochem. Biophys. Res. Commun. 251 1998 811 817
27. M. Höpfner, K. Maaser, B. von Lampe, B. Barthel, C. Hanski, E.O. Riecken, M. Zeitz, and H. Scherubl Growth inhibition and apoptosis induced by P2Y2-receptors in human colorectal carcinoma cells: Involvement of intracellular calcium and cyclic AMP Int. J. Colorectal Dis. 16 2001 154 166
28. E.J. Huang, and L.F. Reichardt Neurotrophins: roles in neuronal development and function Annu. Rev. Neurosci. 24 2001 677 736
29. S. Humbert, R. Dhavan, and L.H. Tsai p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton J. Cell Sci. 113 2000 975 983
30. S. Jenab, and C.E. Inturrisi Retinoic acid regulation of mu opioid receptor and c-fos mRNAs and AP-1 DNA binding in SH-SY5Y neuroblastoma cells Brain Res., Mol. Brain Res. 99 2002 34 39
31. A.C. Katzur, T. Koshimizu, M. Tomic, A. Schultze-Mosgau, O. Ortmann, and S.S. Stojilkovic Expression and responsiveness of P2Y2 receptors inhuman endometrial cancer cell lines J. Clin. Endocrinol. Metab. 84 1999 4085 4091
32. B. Kim, P.S. Leventhal, A.R. Saltiel, and E.L. Feldman Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation J. Biol. Chem. 272 1997 21268 21273
33. R. Lalonde, and C. Strazielle Neurobehavioral characteristics of mice with modified intermediate filament genes Rev. Neurosci. 14 2003 369 385
34. A. La Sala, D. Ferrari, S. Corinti, A. Cavani, F. Di Virgilio, and G. Girolomoni Extracellular ATP induces a distorted maturation of dendritic cells and inhibits their capacity to initiate Th1 responses J. Immunol. 166 2001 1611 1617
35. S.N. Lawson, and P.J. Waddell Soma neurofilament immunoreactivity is related to cell size and fibre conduction velocity in rat primary sensory neurons J. Physiol. 435 1991 41 63
36. S.Y. Lee, S.C. Wolff, R.A. Nicholas, and S.M. O'Grady P2Y receptors modulate ion channel function through interactions involving the C-terminal domain Mol. Pharmacol. 63 2003 878 885
37. S. Leppa, M. Eriksson, R. Saffrich, W. Ansorge, and D. Bohmann Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells Mol. Cell. Biol. 21 2001 4369 4378
38. B.S. Li, L. Zhang, J. Gu, N.D. Amin, and H.C. Pant Integrin a1b1-mediated activation of cyclin-dependent kinase 5 activity is involved in neurite outgrowth and human neurofilament protein H lys-ser-pro tail domain phosphorylation J. Neurosci. 20 2000 6055 6062
39. G. Lopez-Carballo, L. Moreno, S. Masiá, P. Perez, and D. Barettino Activation of the phosphatidylinositol 3-kinase/akt signaling pathway by retinoic acid is required for neural differentiation of SH-SY5Y human neuroblastoma cells J. Biol. Chem. 277 2002 25297 25304
40. K. Maaser, M. Hopfner, A. Jansen, G. Weisinger, M. Gavish, A.P. Kozikowski, A. Weizman, P. Carayon, E.O. Riecken, M. Zeitz, and H. Scherubl Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells Br. J. Cancer 85 2001 1771 1780
41. R. Masgrau, J.M. Servitja, K.W. Young, R. Pardo, E. Sarri, R. Nahorski, and F. Picatoste Characterization of the metabotropic glutamate receptors mediating phospholipase C activation and calcium release in cerebellar granule cells: calcium-dependence of the phospholipase C response Eur. J. Neurosci. 13 2001 248 256
42. C.M. McConville, and J. Forsyth Neuroblastoma-a developmental perspective Cancer Lett. 197 2003 3 9
43. M. Miloso, D. Villa, M. Crimi, S. Galbiati, E. Donzelli, G. Nicolini, and G. Tredici Retinoic acid-induced neuritogenesis of human neuroblastoma SH-SY5Y cells is ERK independent and PKC dependent J. Neurosci. Res. 75 2004 241 252
44. F.B. Morrone, M.C. Jacques-Silva, A.P. Horn, A. Bernardi, G. Schwartsmann, R. Rodnight, and G. Lenz Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines J. Neuro-Oncol. 64 2003 211 218
45. A. Nakagawara Trk receptor tyrosine kinases: a bridge between cancer and neural development Cancer Lett. 169 2001 107 114
46. T. Nakagawa, M. Takahashi, T. Ozaki, K. Watanabe, S. Todo, H. Mizuguchi, T. Hayakawa, and A. Nakagawara Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter Mol. Cell. Biol. 22 2002 2575 2585
47. M.J. Perry, S.N. Lawson, and J. Robertson Neurofilament immunoreactivity in populations of rat primary afferent neurons: a quantitative study of phosphorylated and non-phosphorylated subunits J. Neurocytol. 20 1991 746 758
48. K. Sak, T.E. Webb, K. Samuel, M. Kelve, and J. Jarv Only pyrimidinoceptors are functionally expressed in mouse neuroblastoma cell lines Mol. Cell. Biol. Res. Commun. 1 1999 203 208
49. K. Sak, K. Samuel, M. Kelve, and T.E. Webb Pharmacological characterisation of pyrimidinoceptor responses in NG108-15 cells Eur. J. Pharmacol. 415 2001 127 133
50. M.W. Salter, and L.V. Kalia Src kinases: a hub for NMDA receptor regulation Nat. Rev., Neurosci. 5 2004 317 328
51. M.J. Sanz, and F. Di Virgilio Kinetics and mechanism of ATP-dependent IL-1b release from microglial cells J. Immunol. 164 2000 4893 4898
52. C.L. Sayas, M.T. Moreno-Flores, J. Avila, and F. Wandosell The neurite retraction induced by lysophosphatidic acid increases Alzheimer's disease-like Tau phosphorylation J. Biol. Chem. 274 1999 37046 37052
53. S.M. Schrier, B.I. Florea, G.J. Mulder, J.F. Nagelkerke, and A.P. Ijzerman Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine Biochem. Pharmacol. 63 2002 1119 1126
54. A. Schultze-Mosgau, A.C. Katzur, K.K. Arora, S.S. Stojilkovic, K. Diedrich, and O. Ortmann Characterization of calcium-mobilizing, purinergic P2Y(2) receptors in human ovarian cancer cells Mol. Hum. Reprod. 6 2000 435 442
55. S.R. Shaver P2Y receptors: biological advances and therapeutic opportunities Curr. Opin. Drug Discovery Dev. 4 2001 665 670
56. S.B. Shelton, and G.V.W. Johnson Cyclin-dependent kinase-5 in neurodegeneration J. Neurochem. 88 2004 1313 1326
57. M. Sieber-Blum Factors controlling lineage specification in the neural crest Int. Rev. Cytol. 197 2000 1 33
58. S.L. Song, and S.H. Chueh P2 purinoceptor-mediated inhibition of cyclic AMP accumulation in NG108-15 cells Brain Res. 734 1996 243 251
59. Y. Sugiura, L. Ma, B. Sun, H. Shimada, W.E. Laug, R.C. Seeger, and Y.A. DeClerck The plasminogen activator (PA) system in neuroblastoma: role of PA inhibitor-1 in metastasis Cancer Res. 59 1999 1327 1336
60. M. Tortarolo, P. Veglianese, N. Calvaresi, A. Botturi, C. Rossi, A. Giorgini, A. Migheli, and C. Bendotti Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression Mol. Cell. Neurosci. 23 2003 180 192
61. L. van der Weyden, V. Rakyan, B.M. Luttrell, M.B. Morris, and A.D. Conigrave Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells Immunol. Cell Biol. 78 2000 467 473
62. C. Volonté, M.T. Ciotti, and L. Battistini Development of a method for measuring cell number: application to CNS primary neuronal cultures Cytometry 17 1994 274 276
63. C. Volonté, S. Amadio, F. Cavaliere, N. D'Ambrosi, F. Vacca, and G. Bernardi Extracellular ATP and neurodegeneration Curr. Drug Target CNS Neurol. Disord. 2 2003 403 412
64. H. Yamakuni, N. Kawaguchi, Y. Ohtani, J. Nakamura, T. Katayama, T. Nakagawa, M. Minami, and M. Satoh ATP induces leukemia inhibitory factor mRNA in cultured rat astrocytes J. Neuroimmunol. 129 2002 43 50
65. J. Zhang, P.K. Krishnamurthy, and G.V.W. Johnson Cdk5 phosphorylates p53 and regulates its activity J. Neurochem. 81 2002 307 313
66. A.U. Ziganshin, L.E. Ziganshina, and G. Burnstock P2 receptors: theoretical background for the use in clinical practice Bull. Exp. Biol. Med. 134 2002 313 317