Fungal metabolite sulfamisterin suppresses sphingolipid synthesis through inhibition of serine palmitoyltransferase

Biochemistry

Volumn 44, Issue 1, 2005, Pages 268-277

  Yamaji Hasegawa, Akiko ^a   Takahashi, Atsushi ^b   Tetsuka, Yasuyuki ^b   Senoh, Yukiko ^a   Kobayashi, Toshihide ^a,c  

^a RIKEN   (Japan)

^b Hokko Chem Indust Company Limited ^*  (Japan)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; CELLS; ENZYMES; METABOLITES; MOLECULAR STRUCTURE;

APOPTOSIS; PROLIFERATION; SERINE PALMITOYLTRANSFERASE (SPT); SPHINGOLIPIDS;

LIPIDS;

ANTIBIOTIC AGENT; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; SPHINGOSINE; SULFAMISTERIN; THERMOZYMOCIDIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHO CELL; FUNGUS; IC 50; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ACYLTRANSFERASES; ANIMALS; CHO CELLS; CRICETINAE; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; FUNGI; KINETICS; SERINE C-PALMITOYLTRANSFERASE; SPHINGOLIPIDS; SPHINGOSINE;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 11844253797     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048605l     Document Type: Article

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